| MeSH term | MeSH ID | Detail |
|---|---|---|
| Leukemia, Prolymphocytic | D015463 | 2 associated lipids |
| Decapitation | D049248 | 2 associated lipids |
| Dementia | D003704 | 2 associated lipids |
| Dysbiosis | D064806 | 2 associated lipids |
| Paracoccidioidomycosis | D010229 | 2 associated lipids |
| Intracranial Hemorrhages | D020300 | 2 associated lipids |
| Myoglobinuria | D009212 | 3 associated lipids |
| Dyslexia | D004410 | 3 associated lipids |
| Albinism | D000417 | 3 associated lipids |
| Short Bowel Syndrome | D012778 | 3 associated lipids |
DHA
Dha is a lipid of Fatty Acyls (FA) class. Dha is associated with abnormalities such as Atherosclerosis, Consumption-archaic term for TB, Chronic disease, Cardiovascular Diseases and Diabetes Mellitus, Non-Insulin-Dependent. The involved functions are known as Inflammation, Oxidation, fatty acid oxidation, Fatty Acid Metabolism and Lipid Metabolism. Dha often locates in Hepatic, Protoplasm, Mucous Membrane, Epithelium and outer membrane. The associated genes with DHA are IMPACT gene, FATE1 gene, GAPDH gene, THOC4 gene and SLC33A1 gene. The related lipids are stearidonic acid, Fatty Acids, Total cholesterol, Lipopolysaccharides and Dietary Fatty Acid. The related experimental models are Mouse Model, Transgenic Model, Animal Disease Models and Arthritis, Experimental.
Cross Reference
Introduction
To understand associated biological information of DHA, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with DHA?
DHA is suspected in Cardiovascular Diseases, Obesity, Ischemia, Hypertensive disease, Coronary Arteriosclerosis, Cerebrovascular accident and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with DHA
PubChem Associated disorders and diseases
What pathways are associated with DHA
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with DHA?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with DHA?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with DHA?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with DHA?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with DHA?
Mouse Model
Mouse Model are used in the study 'Homeostatic regulation of photoreceptor cell integrity: significance of the potent mediator neuroprotectin D1 biosynthesized from docosahexaenoic acid: the Proctor Lecture.' (Bazan NG, 2007), Mouse Model are used in the study 'Omega-3 fatty acids EPA and DHA: health benefits throughout life.' (Swanson D et al., 2012), Mouse Model are used in the study 'Docosahexaenoic acid attenuates hepatic inflammation, oxidative stress, and fibrosis without decreasing hepatosteatosis in a Ldlr(-/-) mouse model of western diet-induced nonalcoholic steatohepatitis.' (Depner CM et al., 2013) and Mouse Model are used in the study 'Wax esters from the marine copepod Calanus finmarchicus reduce diet-induced obesity and obesity-related metabolic disorders in mice.' (Höper AC et al., 2014).
Transgenic Model
Transgenic Model are used in the study 'Loss of MAP function leads to hippocampal synapse loss and deficits in the Morris Water Maze with aging.' (Ma QL et al., 2014).
Animal Disease Models
Animal Disease Models are used in the study 'Fish oil increases muscle protein mass and modulates Akt/FOXO, TLR4, and NOD signaling in weanling piglets after lipopolysaccharide challenge.' (Liu Y et al., 2013).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with DHA
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Shikano M et al. | Complete discrimination of docosahexaenoate from arachidonate by 85 kDa cytosolic phospholipase A2 during the hydrolysis of diacyl- and alkenylacylglycerophosphoethanolamine. | 1994 | Biochim. Biophys. Acta | pmid:8180247 |
| Bouziane M et al. | Dietary protein deficiency affects n-3 and n-6 polyunsaturated fatty acids hepatic storage and very low density lipoprotein transport in rats on different diets. | 1994 | Lipids | pmid:8177019 |
| Andersson L et al. | Hydrolysis of phosphatidylethanolamine by human pancreatic phospholipase A2. Effect of bile salts. | 1994 | Scand. J. Gastroenterol. | pmid:8171289 |
| Ter-Karapetian VA | [The use of marine products in the prevention and treatment of vascular diseases of the heart and brain]. | 1994 | Voen Med Zh | pmid:8165800 |
| Demoz A et al. | Modulation of plasma and hepatic oxidative status and changes in plasma lipid profile by n-3 (EPA and DHA), n-6 (corn oil) and a 3-thia fatty acid in rats. | 1994 | Biochim. Biophys. Acta | pmid:8161562 |
| Anderson RE et al. | Plasma lipid changes in PRCD-affected and normal miniature poodles given oral supplements of linseed oil. Indications for the involvement of n-3 fatty acids in inherited retinal degenerations. | 1994 | Exp. Eye Res. | pmid:8157107 |
| Rodriguez de Turco EB et al. | Docosahexaenoic acid is taken up by the inner segment of frog photoreceptors leading to an active synthesis of docosahexaenoyl-inositol lipids: similarities in metabolism in vivo and in vitro. | 1994 | Curr. Eye Res. | pmid:8156822 |
| Zhu BQ et al. | Is the reduction of myocardial infarct size by dietary fish oil the result of altered platelet function? | 1994 | Am. Heart J. | pmid:8154411 |
| Leung FW | Prostaglandins mediate fish oil protection against ethanol-induced gastric mucosal injury in rats. | 1994 | Dig. Dis. Sci. | pmid:8149856 |
| Shiina T et al. | Eicosapentaenoic acid and docosahexaenoic acid suppress the proliferation of vascular smooth muscle cells. | 1993 | Atherosclerosis | pmid:8141854 |
| Bénistant C et al. | Platelet inhibitory functions of aortic endothelial cells. Effects of eicosapentaenoic and docosahexaenoic acids. | 1993 | Atherosclerosis | pmid:8141848 |
| Schjøtt J et al. | Infusion of EPA and DHA lipid emulsions: effects on heart lipids and tolerance to ischaemia-reperfusion in the isolated rat heart. | 1993 | Scand. J. Clin. Lab. Invest. | pmid:8140399 |
| Hardy SJ et al. | In vitro activation of rat brain protein kinase C by polyenoic very-long-chain fatty acids. | 1994 | J. Neurochem. | pmid:8133282 |
| Piatti G et al. | Delaying effects of dietary eicosapentaenoic-docosahexaenoic acids on development of "fatty streaks" in hypercholesterolaemic rabbits. A morphological study by scanning electron microscopy. | 1993 | Drugs Exp Clin Res | pmid:8131713 |
| Honoré E et al. | External blockade of the major cardiac delayed-rectifier K+ channel (Kv1.5) by polyunsaturated fatty acids. | 1994 | Proc. Natl. Acad. Sci. U.S.A. | pmid:8127910 |
| Henderson WR et al. | Oral absorption of omega-3 fatty acids in patients with cystic fibrosis who have pancreatic insufficiency and in healthy control subjects. | 1994 | J. Pediatr. | pmid:8120709 |
| Somers SD and Erickson KL | Alteration of tumor necrosis factor-alpha production by macrophages from mice fed diets high in eicosapentaenoic and docosahexaenoic fatty acids. | 1994 | Cell. Immunol. | pmid:8118867 |
| Wakabayashi S et al. | In vivo cerebral incorporation of radiolabeled fatty acids after acute unilateral orbital enucleation in adult hooded Long-Evans rats. | 1994 | J. Cereb. Blood Flow Metab. | pmid:8113326 |
| Alvarez RA et al. | Docosapentaenoic acid is converted to docosahexaenoic acid in the retinas of normal and prcd-affected miniature poodle dogs. | 1994 | Invest. Ophthalmol. Vis. Sci. | pmid:8112987 |
| Ikai K et al. | Leukotriene A4 hydrolase in human skin. | 1994 | J. Invest. Dermatol. | pmid:8106755 |
| Spady DK | Regulatory effects of individual n-6 and n-3 polyunsaturated fatty acids on LDL transport in the rat. | 1993 | J. Lipid Res. | pmid:8105015 |
| Bourre JM et al. | Dietary alpha-linolenic acid at 1.3 g/kg maintains maximal docosahexaenoic acid concentration in brain, heart and liver of adult rats. | 1993 | J. Nutr. | pmid:8100576 |
| Orii T et al. | [Peroxisomal disorders--DNA analysis]. | 1993 | Nippon Rinsho | pmid:8096253 |
| Crawford MA | Aspirin in pregnancy. | 1993 | Lancet | pmid:8095644 |
| Hanai T et al. | Comparison of prostanoids and their precursor fatty acids in human hepatocellular carcinoma and noncancerous reference tissues. | 1993 | J. Surg. Res. | pmid:8094103 |
| Fonlupt P et al. | Incorporation of arachidonic and docosahexaenoic acids into phospholipids of rat brain membranes. | 1994 | Neurosci. Lett. | pmid:8084475 |
| Alberghina M et al. | Differential transport of docosahexaenoate and palmitate through the blood-retina and blood-brain barrier of the rat. | 1994 | Neurosci. Lett. | pmid:8084474 |
| Pyzh MV et al. | [Food supplement containing ω-3 polyunsaturated fatty acids prevents experimental thrombotic occlusion of coronary arteries in dogs]. | 1993 | Kardiologiia | pmid:8084128 |
| Jump DB et al. | Coordinate regulation of glycolytic and lipogenic gene expression by polyunsaturated fatty acids. | 1994 | J. Lipid Res. | pmid:8077846 |
| McVeigh GE et al. | Fish oil improves arterial compliance in non-insulin-dependent diabetes mellitus. | 1994 | Arterioscler. Thromb. | pmid:8068603 |
| Sukenik A et al. | Dietary lipids from marine unicellular algae enhance the amount of liver and blood omega-3 fatty acids in rats. | 1994 | Ann. Nutr. Metab. | pmid:8067689 |
| Karanian JW et al. | Lipoxygenase stimulating effects of hydroxylated docosahexaenoates produced by human platelets. | 1994 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:8066103 |
| Takahashi M et al. | Effect of docosahexaenoic acid on azoxymethane-induced colon carcinogenesis in rats. | 1994 | Cancer Lett. | pmid:8062213 |
| Reddy S et al. | The influence of maternal vegetarian diet on essential fatty acid status of the newborn. | 1994 | Eur J Clin Nutr | pmid:8055852 |
| Brand MD et al. | Liposomes from mammalian liver mitochondria are more polyunsaturated and leakier to protons than those from reptiles. | 1994 | Comp. Biochem. Physiol. Biochem. Mol. Biol. | pmid:8055185 |
| North JA et al. | Cell fatty acid composition affects free radical formation during lipid peroxidation. | 1994 | Am. J. Physiol. | pmid:8048478 |
| Felouati BE et al. | Oestradiol-induced changes in the composition of phospholipid classes of quail oviduct: specific replacement of arachidonic acid by docosahexaenoic acid in alkenylacyl-glycerophosphoethanolamine. | 1994 | Biochem. J. | pmid:8042978 |
| Wang H et al. | The effects of n-3 fatty acids on the secretion of carboxyl-terminally truncated forms of human apoprotein B. | 1994 | J. Biol. Chem. | pmid:8034600 |
| Haglund O et al. | Effects of fish oil on some parameters of fibrinolysis and lipoprotein(a) in healthy subjects. | 1994 | Am. J. Cardiol. | pmid:8023790 |
| Sacks FM et al. | Short report: the effect of fish oil on blood pressure and high-density lipoprotein-cholesterol levels in phase I of the Trials of Hypertension Prevention. | 1994 | J. Hypertens. | pmid:8021472 |
| Shahar E et al. | Dietary n-3 polyunsaturated fatty acids and smoking-related chronic obstructive pulmonary disease. Atherosclerosis Risk in Communities Study Investigators. | 1994 | N. Engl. J. Med. | pmid:8015569 |
| Carlson SE et al. | Long-chain fatty acids and early visual and cognitive development of preterm infants. | 1994 | Eur J Clin Nutr | pmid:7995262 |
| Belluzzi A et al. | Effects of new fish oil derivative on fatty acid phospholipid-membrane pattern in a group of Crohn's disease patients. | 1994 | Dig. Dis. Sci. | pmid:7995183 |
| Bright JM et al. | The effects of n-3 fatty acid supplementation on bleeding time, plasma fatty acid composition, and in vitro platelet aggregation in cats. | 1994 Jul-Aug | J. Vet. Intern. Med. | pmid:7983618 |
| Brossard N et al. | Stable isotope tracer and gas-chromatography combustion isotope ratio mass spectrometry to study the in vivo compartmental metabolism of docosahexaenoic acid. | 1994 | Anal. Biochem. | pmid:7978245 |
| Thies F et al. | Preferential incorporation of sn-2 lysoPC DHA over unesterified DHA in the young rat brain. | 1994 | Am. J. Physiol. | pmid:7977854 |
| Imre SG et al. | Increased proportion of docosahexanoic acid and high lipid peroxidation capacity in erythrocytes of stroke patients. | 1994 | Stroke | pmid:7974583 |
| Yano Y et al. | Production of docosahexaenoic acid by marine bacteria isolated from deep sea fish. | 1994 | Lipids | pmid:7968276 |
| Hardy SC and Kleinman RE | Fat and cholesterol in the diet of infants and young children: implications for growth, development, and long-term health. | 1994 | J. Pediatr. | pmid:7965456 |
| Gibson RA et al. | Ratios of linoleic acid to alpha-linolenic acid in formulas for term infants. | 1994 | J. Pediatr. | pmid:7965453 |