DHA

Dha is a lipid of Fatty Acyls (FA) class. Dha is associated with abnormalities such as Atherosclerosis, Consumption-archaic term for TB, Chronic disease, Cardiovascular Diseases and Diabetes Mellitus, Non-Insulin-Dependent. The involved functions are known as Inflammation, Oxidation, fatty acid oxidation, Fatty Acid Metabolism and Lipid Metabolism. Dha often locates in Hepatic, Protoplasm, Mucous Membrane, Epithelium and outer membrane. The associated genes with DHA are IMPACT gene, FATE1 gene, GAPDH gene, THOC4 gene and SLC33A1 gene. The related lipids are stearidonic acid, Fatty Acids, Total cholesterol, Lipopolysaccharides and Dietary Fatty Acid. The related experimental models are Mouse Model, Transgenic Model, Animal Disease Models and Arthritis, Experimental.

Cross Reference

Introduction

To understand associated biological information of DHA, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with DHA?

DHA is suspected in Cardiovascular Diseases, Obesity, Ischemia, Hypertensive disease, Coronary Arteriosclerosis, Cerebrovascular accident and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with DHA

MeSH term MeSH ID Detail
Dyslexia D004410 3 associated lipids
Albinism D000417 3 associated lipids
Short Bowel Syndrome D012778 3 associated lipids
Depression, Postpartum D019052 3 associated lipids
Dyskinesias D020820 3 associated lipids
Biliary Atresia D001656 4 associated lipids
Spinocerebellar Ataxias D020754 4 associated lipids
Milk Hypersensitivity D016269 4 associated lipids
Diabetes Complications D048909 4 associated lipids
Hypercalciuria D053565 4 associated lipids
Intracranial Arteriosclerosis D002537 4 associated lipids
Chondrodysplasia Punctata, Rhizomelic D018902 4 associated lipids
Peroxisomal Disorders D018901 5 associated lipids
Macular Degeneration D008268 5 associated lipids
Chronic Pain D059350 5 associated lipids
Vibrio Infections D014735 5 associated lipids
Abortion, Habitual D000026 5 associated lipids
Keratitis, Herpetic D016849 5 associated lipids
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma D054218 5 associated lipids
Hyperlipoproteinemia Type IV D006953 6 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with DHA

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with DHA?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with DHA?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with DHA?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with DHA?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with DHA?

Mouse Model

Mouse Model are used in the study 'Homeostatic regulation of photoreceptor cell integrity: significance of the potent mediator neuroprotectin D1 biosynthesized from docosahexaenoic acid: the Proctor Lecture.' (Bazan NG, 2007), Mouse Model are used in the study 'Omega-3 fatty acids EPA and DHA: health benefits throughout life.' (Swanson D et al., 2012), Mouse Model are used in the study 'Docosahexaenoic acid attenuates hepatic inflammation, oxidative stress, and fibrosis without decreasing hepatosteatosis in a Ldlr(-/-) mouse model of western diet-induced nonalcoholic steatohepatitis.' (Depner CM et al., 2013) and Mouse Model are used in the study 'Wax esters from the marine copepod Calanus finmarchicus reduce diet-induced obesity and obesity-related metabolic disorders in mice.' (Höper AC et al., 2014).

Transgenic Model

Transgenic Model are used in the study 'Loss of MAP function leads to hippocampal synapse loss and deficits in the Morris Water Maze with aging.' (Ma QL et al., 2014).

Animal Disease Models

Animal Disease Models are used in the study 'Fish oil increases muscle protein mass and modulates Akt/FOXO, TLR4, and NOD signaling in weanling piglets after lipopolysaccharide challenge.' (Liu Y et al., 2013).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with DHA

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Per page 10 20 50 100 | Total 7336
Authors Title Published Journal PubMed Link
Li L et al. Resolvin D1 promotes the interleukin-4-induced alternative activation in BV-2 microglial cells. 2014 J Neuroinflammation pmid:24708771
Chatterjee A et al. The pro-resolving lipid mediator maresin 1 (MaR1) attenuates inflammatory signaling pathways in vascular smooth muscle and endothelial cells. 2014 PLoS ONE pmid:25409514
Abe E et al. Novel lysophospholipid acyltransferase PLAT1 of Aurantiochytrium limacinum F26-b responsible for generation of palmitate-docosahexaenoate-phosphatidylcholine and phosphatidylethanolamine. 2014 PLoS ONE pmid:25090090
Lane K et al. Bioavailability and potential uses of vegetarian sources of omega-3 fatty acids: a review of the literature. 2014 Crit Rev Food Sci Nutr pmid:24261532
Maffei S et al. Effects of ω-3 PUFAs supplementation on myocardial function and oxidative stress markers in typical Rett syndrome. 2014 Mediators Inflamm. pmid:24526821
Saito H and Ishikawa S Lipid classes and fatty acid profile of cultured and wild black rockfish, Sebastes schlegeli. 2014 J Oleo Sci pmid:24829130
Nakagawa F et al. 4-Hydroxy hexenal derived from dietary n-3 polyunsaturated fatty acids induces anti-oxidative enzyme heme oxygenase-1 in multiple organs. 2014 Biochem. Biophys. Res. Commun. pmid:24361890
Yamanushi TT et al. Oral administration of eicosapentaenoic acid or docosahexaenoic acid modifies cardiac function and ameliorates congestive heart failure in male rats. 2014 J. Nutr. pmid:24523492
Russell CD and Schwarze J The role of pro-resolution lipid mediators in infectious disease. 2014 Immunology pmid:24400794
AlSaleh A et al. Interaction between a CSK gene variant and fish oil intake influences blood pressure in healthy adults. 2014 J. Nutr. pmid:24401815
Paterniti I et al. Docosahexaenoic acid attenuates the early inflammatory response following spinal cord injury in mice: in-vivo and in-vitro studies. 2014 J Neuroinflammation pmid:24405628
Chen J et al. Aspirin-triggered resolvin D1 down-regulates inflammatory responses and protects against endotoxin-induced acute kidney injury. 2014 Toxicol. Appl. Pharmacol. pmid:24709673
Kermack AJ et al. A randomised controlled trial of a preconceptional dietary intervention in women undergoing IVF treatment (PREPARE trial). 2014 BMC Womens Health pmid:25407227
Wang JL et al. Preparation and characterization of novel lipid carriers containing microalgae oil for food applications. 2014 J. Food Sci. pmid:24446860
Chang G et al. The relationship of oxygen uptake rate and k(L)a with rheological properties in high cell density cultivation of docosahexaenoic acid by Schizochytrium sp. S31. 2014 Bioresour. Technol. pmid:24292203
Rius B et al. Resolvin D1 primes the resolution process initiated by calorie restriction in obesity-induced steatohepatitis. 2014 FASEB J. pmid:24249635
Liu L et al. Higher efficacy of dietary DHA provided as a phospholipid than as a triglyceride for brain DHA accretion in neonatal piglets. 2014 J. Lipid Res. pmid:24470588
de Waal H et al. The effect of souvenaid on functional brain network organisation in patients with mild Alzheimer's disease: a randomised controlled study. 2014 PLoS ONE pmid:24475144
Desai A et al. Depletion of brain docosahexaenoic acid impairs recovery from traumatic brain injury. 2014 PLoS ONE pmid:24475126
Amiri-Jami M et al. Engineering of EPA/DHA omega-3 fatty acid production by Lactococcus lactis subsp. cremoris MG1363. 2014 Appl. Microbiol. Biotechnol. pmid:24389665