| MeSH term | MeSH ID | Detail |
|---|---|---|
| Keratitis, Herpetic | D016849 | 5 associated lipids |
| Phenylketonuria, Maternal | D017042 | 1 associated lipids |
| Glucose Intolerance | D018149 | 13 associated lipids |
| Carcinoma, Embryonal | D018236 | 8 associated lipids |
| Trophoblastic Tumor, Placental Site | D018245 | 1 associated lipids |
| Pneumonia, Bacterial | D018410 | 16 associated lipids |
| Ventricular Dysfunction, Left | D018487 | 33 associated lipids |
| Sepsis | D018805 | 11 associated lipids |
| Carcinoma, Lewis Lung | D018827 | 22 associated lipids |
| Peroxisomal Disorders | D018901 | 5 associated lipids |
DHA
Dha is a lipid of Fatty Acyls (FA) class. Dha is associated with abnormalities such as Atherosclerosis, Consumption-archaic term for TB, Chronic disease, Cardiovascular Diseases and Diabetes Mellitus, Non-Insulin-Dependent. The involved functions are known as Inflammation, Oxidation, fatty acid oxidation, Fatty Acid Metabolism and Lipid Metabolism. Dha often locates in Hepatic, Protoplasm, Mucous Membrane, Epithelium and outer membrane. The associated genes with DHA are IMPACT gene, FATE1 gene, GAPDH gene, THOC4 gene and SLC33A1 gene. The related lipids are stearidonic acid, Fatty Acids, Total cholesterol, Lipopolysaccharides and Dietary Fatty Acid. The related experimental models are Mouse Model, Transgenic Model, Animal Disease Models and Arthritis, Experimental.
Cross Reference
Introduction
To understand associated biological information of DHA, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with DHA?
DHA is suspected in Cardiovascular Diseases, Obesity, Ischemia, Hypertensive disease, Coronary Arteriosclerosis, Cerebrovascular accident and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with DHA
PubChem Associated disorders and diseases
What pathways are associated with DHA
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with DHA?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with DHA?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with DHA?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with DHA?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with DHA?
Mouse Model
Mouse Model are used in the study 'Homeostatic regulation of photoreceptor cell integrity: significance of the potent mediator neuroprotectin D1 biosynthesized from docosahexaenoic acid: the Proctor Lecture.' (Bazan NG, 2007), Mouse Model are used in the study 'Omega-3 fatty acids EPA and DHA: health benefits throughout life.' (Swanson D et al., 2012), Mouse Model are used in the study 'Docosahexaenoic acid attenuates hepatic inflammation, oxidative stress, and fibrosis without decreasing hepatosteatosis in a Ldlr(-/-) mouse model of western diet-induced nonalcoholic steatohepatitis.' (Depner CM et al., 2013) and Mouse Model are used in the study 'Wax esters from the marine copepod Calanus finmarchicus reduce diet-induced obesity and obesity-related metabolic disorders in mice.' (Höper AC et al., 2014).
Transgenic Model
Transgenic Model are used in the study 'Loss of MAP function leads to hippocampal synapse loss and deficits in the Morris Water Maze with aging.' (Ma QL et al., 2014).
Animal Disease Models
Animal Disease Models are used in the study 'Fish oil increases muscle protein mass and modulates Akt/FOXO, TLR4, and NOD signaling in weanling piglets after lipopolysaccharide challenge.' (Liu Y et al., 2013).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with DHA
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Mori TA | Dietary n-3 PUFA and CVD: a review of the evidence. | 2014 | Proc Nutr Soc | pmid:24119287 |
| Zhu G et al. | Enhanced production of docosahexaenoic acid in mammalian cells. | 2014 | PLoS ONE | pmid:24788769 |
| Martin CR et al. | Resolvin D1 and lipoxin A4 improve alveolarization and normalize septal wall thickness in a neonatal murine model of hyperoxia-induced lung injury. | 2014 | PLoS ONE | pmid:24892762 |
| Makrides M et al. | Four-year follow-up of children born to women in a randomized trial of prenatal DHA supplementation. | 2014 | JAMA | pmid:24794375 |
| Mirakaj V et al. | Vagus nerve controls resolution and pro-resolving mediators of inflammation. | 2014 | J. Exp. Med. | pmid:24863066 |
| Chen R et al. | [Effects of docosahexaenoic acid on hypoxia-induced pulmonary arterial hypertension]. | 2014 | Zhonghua Jie He He Hu Xi Za Zhi | pmid:24796591 |
| Ooi SY and Andrews JM | Commentary: The association between high dietary intake of docosahexaenoic acid and reduced risk of Crohn's disease. | 2014 | Aliment. Pharmacol. Ther. | pmid:24803245 |
| Ramon S et al. | The specialized proresolving mediator 17-HDHA enhances the antibody-mediated immune response against influenza virus: a new class of adjuvant? | 2014 | J. Immunol. | pmid:25392529 |
| Velten M et al. | Maternal dietary docosahexaenoic acid supplementation attenuates fetal growth restriction and enhances pulmonary function in a newborn mouse model of perinatal inflammation. | 2014 | J. Nutr. | pmid:24453131 |
| Mereghetti P et al. | A Fourier transform infrared spectroscopy study of cell membrane domain modifications induced by docosahexaenoic acid. | 2014 | Biochim. Biophys. Acta | pmid:25018005 |
| Lager S et al. | Differential regulation of placental amino acid transport by saturated and unsaturated fatty acids. | 2014 | Am. J. Physiol., Cell Physiol. | pmid:25143349 |
| Nishinaka T et al. | Involvement of the long-chain fatty acid receptor GPR40 in depression-related behavior. | 2014 | J. Pharmacol. Sci. | pmid:24758921 |
| Nagao K et al. | Comparison of the lipid-lowering effects of four different n-3 highly unsaturated fatty acids in HepG2 cells. | 2014 | J Oleo Sci | pmid:25213447 |
| Nanjappa D et al. | Oxylipin diversity in the diatom family Leptocylindraceae reveals DHA derivatives in marine diatoms. | 2014 | Mar Drugs | pmid:24445306 |
| Begum G et al. | Docosahexaenoic acid reduces ER stress and abnormal protein accumulation and improves neuronal function following traumatic brain injury. | 2014 | J. Neurosci. | pmid:24599472 |
| Koppenol A et al. | Effect of the ratio of dietary n-3 fatty acids eicosapentaenoic acid and docosahexaenoic acid on broiler breeder performance, egg quality, and yolk fatty acid composition at different breeder ages. | 2014 | Poult. Sci. | pmid:24604849 |
| Levy BD and Serhan CN | Resolution of acute inflammation in the lung. | 2014 | Annu. Rev. Physiol. | pmid:24313723 |
| Stoffel W et al. | Obesity resistance and deregulation of lipogenesis in Δ6-fatty acid desaturase (FADS2) deficiency. | 2014 | EMBO Rep. | pmid:24378641 |
| Jiang M et al. | Isolation and characterization of the diatom Phaeodactylum Δ5-elongase gene for transgenic LC-PUFA production in Pichia pastoris. | 2014 | Mar Drugs | pmid:24608969 |
| Hixson SM et al. | Changes in tissue lipid and fatty acid composition of farmed rainbow trout in response to dietary camelina oil as a replacement of fish oil. | 2014 | Lipids | pmid:24264359 |