| MeSH term | MeSH ID | Detail |
|---|---|---|
| Death, Sudden, Cardiac | D016757 | 12 associated lipids |
| Neurodegenerative Diseases | D019636 | 32 associated lipids |
| Lupus Nephritis | D008181 | 8 associated lipids |
| Parkinsonian Disorders | D020734 | 20 associated lipids |
| Neuralgia | D009437 | 28 associated lipids |
| Peripheral Nerve Injuries | D059348 | 6 associated lipids |
| Muscular Dystrophy, Duchenne | D020388 | 11 associated lipids |
| Keratitis, Herpetic | D016849 | 5 associated lipids |
| Sleep Wake Disorders | D012893 | 7 associated lipids |
| Burkholderia Infections | D019121 | 7 associated lipids |
DHA
Dha is a lipid of Fatty Acyls (FA) class. Dha is associated with abnormalities such as Atherosclerosis, Consumption-archaic term for TB, Chronic disease, Cardiovascular Diseases and Diabetes Mellitus, Non-Insulin-Dependent. The involved functions are known as Inflammation, Oxidation, fatty acid oxidation, Fatty Acid Metabolism and Lipid Metabolism. Dha often locates in Hepatic, Protoplasm, Mucous Membrane, Epithelium and outer membrane. The associated genes with DHA are IMPACT gene, FATE1 gene, GAPDH gene, THOC4 gene and SLC33A1 gene. The related lipids are stearidonic acid, Fatty Acids, Total cholesterol, Lipopolysaccharides and Dietary Fatty Acid. The related experimental models are Mouse Model, Transgenic Model, Animal Disease Models and Arthritis, Experimental.
Cross Reference
Introduction
To understand associated biological information of DHA, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with DHA?
DHA is suspected in Cardiovascular Diseases, Obesity, Ischemia, Hypertensive disease, Coronary Arteriosclerosis, Cerebrovascular accident and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with DHA
PubChem Associated disorders and diseases
What pathways are associated with DHA
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with DHA?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with DHA?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with DHA?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with DHA?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with DHA?
Mouse Model
Mouse Model are used in the study 'Homeostatic regulation of photoreceptor cell integrity: significance of the potent mediator neuroprotectin D1 biosynthesized from docosahexaenoic acid: the Proctor Lecture.' (Bazan NG, 2007), Mouse Model are used in the study 'Omega-3 fatty acids EPA and DHA: health benefits throughout life.' (Swanson D et al., 2012), Mouse Model are used in the study 'Docosahexaenoic acid attenuates hepatic inflammation, oxidative stress, and fibrosis without decreasing hepatosteatosis in a Ldlr(-/-) mouse model of western diet-induced nonalcoholic steatohepatitis.' (Depner CM et al., 2013) and Mouse Model are used in the study 'Wax esters from the marine copepod Calanus finmarchicus reduce diet-induced obesity and obesity-related metabolic disorders in mice.' (Höper AC et al., 2014).
Transgenic Model
Transgenic Model are used in the study 'Loss of MAP function leads to hippocampal synapse loss and deficits in the Morris Water Maze with aging.' (Ma QL et al., 2014).
Animal Disease Models
Animal Disease Models are used in the study 'Fish oil increases muscle protein mass and modulates Akt/FOXO, TLR4, and NOD signaling in weanling piglets after lipopolysaccharide challenge.' (Liu Y et al., 2013).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with DHA
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
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| Kelley DS et al. | Docosahexaenoic acid supplementation improved lipocentric but not glucocentric markers of insulin sensitivity in hypertriglyceridemic men. | 2012 | Metab Syndr Relat Disord | pmid:21999398 |
| Murphy RA et al. | n-3 polyunsaturated fatty acids: the potential role for supplementation in cancer. | 2012 | Curr Opin Clin Nutr Metab Care | pmid:22366922 |
| Larsen BM et al. | Pre-treatment with an intravenous lipid emulsion containing fish oil (eicosapentaenoic and docosahexaenoic acid) decreases inflammatory markers after open-heart surgery in infants: a randomized, controlled trial. | 2012 | Clin Nutr | pmid:22136963 |
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| Phang M et al. | Acute supplementation with eicosapentaenoic acid reduces platelet microparticle activity in healthy subjects. | 2012 | J. Nutr. Biochem. | pmid:22137256 |
| Ortiz-Alvarado O et al. | Omega-3 fatty acids eicosapentaenoic acid and docosahexaenoic acid in the management of hypercalciuric stone formers. | 2012 | Urology | pmid:22000931 |
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| Hall JC et al. | Docosahexaenoic acid, but not eicosapentaenoic acid, reduces the early inflammatory response following compression spinal cord injury in the rat. | 2012 | J. Neurochem. | pmid:22404382 |
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| Betancor MB et al. | Selenium inclusion decreases oxidative stress indicators and muscle injuries in sea bass larvae fed high-DHA microdiets. | 2012 | Br. J. Nutr. | pmid:22409905 |
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| Betancor MB et al. | Vitamin C enhances vitamin E status and reduces oxidative stress indicators in sea bass larvae fed high DHA microdiets. | 2012 | Lipids | pmid:23086553 |
| Hou L et al. | Reduction of n-3 PUFAs, specifically DHA and EPA, and enhancement of peroxisomal beta-oxidation in type 2 diabetic rat heart. | 2012 | Cardiovasc Diabetol | pmid:23057715 |
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| Serhan CN et al. | Macrophage proresolving mediator maresin 1 stimulates tissue regeneration and controls pain. | 2012 | FASEB J. | pmid:22253477 |
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| Tian H et al. | 14S,21R-dihydroxy-docosahexaenoic acid treatment enhances mesenchymal stem cell amelioration of renal ischemia/reperfusion injury. | 2012 | Stem Cells Dev. | pmid:21846180 |
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| Finlin BS et al. | DHA reduces the atrophy-associated Fn14 protein in differentiated myotubes during coculture with macrophages. | 2012 | J. Nutr. Biochem. | pmid:21852085 |
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| Kisos H et al. | Increased neuronal α-synuclein pathology associates with its accumulation in oligodendrocytes in mice modeling α-synucleinopathies. | 2012 | PLoS ONE | pmid:23077527 |
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| Richardson AJ et al. | Docosahexaenoic acid for reading, cognition and behavior in children aged 7-9 years: a randomized, controlled trial (the DOLAB Study). | 2012 | PLoS ONE | pmid:22970149 |
| Rasti B et al. | Comparative study of the oxidative and physical stability of liposomal and nanoliposomal polyunsaturated fatty acids prepared with conventional and Mozafari methods. | 2012 | Food Chem | pmid:22980870 |
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| Moore RL et al. | Oxidative stability of an extended shelf-life dairy-based beverage system designed to contribute to heart health. | 2012 | J. Dairy Sci. | pmid:22981572 |
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| Angulo J et al. | Effects of polyunsaturated fatty acids from plant oils and algae on milk fat yield and composition are associated with mammary lipogenic and SREBF1 gene expression. | 2012 | Animal | pmid:22717104 |
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| Jin F et al. | Supplementation of milled chia seeds increases plasma ALA and EPA in postmenopausal women. | 2012 | Plant Foods Hum Nutr | pmid:22538527 |
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| Rossmeisl M et al. | Metabolic effects of n-3 PUFA as phospholipids are superior to triglycerides in mice fed a high-fat diet: possible role of endocannabinoids. | 2012 | PLoS ONE | pmid:22701720 |
| Xiong A et al. | Distinct roles of different forms of vitamin E in DHA-induced apoptosis in triple-negative breast cancer cells. | 2012 | Mol Nutr Food Res | pmid:22707267 |
| Carter JR et al. | Fish oil and neurovascular control in humans. | 2012 | Am. J. Physiol. Heart Circ. Physiol. | pmid:22707560 |
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| Dhobale M et al. | Association of brain-derived neurotrophic factor and tyrosine kinase B receptor in pregnancy. | 2012 | Neuroscience | pmid:22542551 |
| Sharma S et al. | High-fat diet transition reduces brain DHA levels associated with altered brain plasticity and behaviour. | 2012 | Sci Rep | pmid:22666534 |
| Tang X et al. | Short term effects of different omega-3 fatty acid formulation on lipid metabolism in mice fed high or low fat diet. | 2012 | Lipids Health Dis | pmid:22676394 |
| Imam MH and Lindor KD | Primary sclerosing cholangitis: providing a safe and effective treatment. | 2012 | Expert Rev Gastroenterol Hepatol | pmid:22646247 |
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