| MeSH term | MeSH ID | Detail |
|---|---|---|
| Melanoma | D008545 | 69 associated lipids |
| Colitis | D003092 | 69 associated lipids |
| Coronary Disease | D003327 | 70 associated lipids |
| Hyperlipidemias | D006949 | 73 associated lipids |
| Leukemia | D007938 | 74 associated lipids |
| Stomach Ulcer | D013276 | 75 associated lipids |
| Alzheimer Disease | D000544 | 76 associated lipids |
| Pancreatic Neoplasms | D010190 | 77 associated lipids |
| Diabetes Mellitus, Experimental | D003921 | 85 associated lipids |
| Atherosclerosis | D050197 | 85 associated lipids |
DHA
Dha is a lipid of Fatty Acyls (FA) class. Dha is associated with abnormalities such as Atherosclerosis, Consumption-archaic term for TB, Chronic disease, Cardiovascular Diseases and Diabetes Mellitus, Non-Insulin-Dependent. The involved functions are known as Inflammation, Oxidation, fatty acid oxidation, Fatty Acid Metabolism and Lipid Metabolism. Dha often locates in Hepatic, Protoplasm, Mucous Membrane, Epithelium and outer membrane. The associated genes with DHA are IMPACT gene, FATE1 gene, GAPDH gene, THOC4 gene and SLC33A1 gene. The related lipids are stearidonic acid, Fatty Acids, Total cholesterol, Lipopolysaccharides and Dietary Fatty Acid. The related experimental models are Mouse Model, Transgenic Model, Animal Disease Models and Arthritis, Experimental.
Cross Reference
Introduction
To understand associated biological information of DHA, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with DHA?
DHA is suspected in Cardiovascular Diseases, Obesity, Ischemia, Hypertensive disease, Coronary Arteriosclerosis, Cerebrovascular accident and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with DHA
PubChem Associated disorders and diseases
What pathways are associated with DHA
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with DHA?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with DHA?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with DHA?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with DHA?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with DHA?
Mouse Model
Mouse Model are used in the study 'Homeostatic regulation of photoreceptor cell integrity: significance of the potent mediator neuroprotectin D1 biosynthesized from docosahexaenoic acid: the Proctor Lecture.' (Bazan NG, 2007), Mouse Model are used in the study 'Omega-3 fatty acids EPA and DHA: health benefits throughout life.' (Swanson D et al., 2012), Mouse Model are used in the study 'Docosahexaenoic acid attenuates hepatic inflammation, oxidative stress, and fibrosis without decreasing hepatosteatosis in a Ldlr(-/-) mouse model of western diet-induced nonalcoholic steatohepatitis.' (Depner CM et al., 2013) and Mouse Model are used in the study 'Wax esters from the marine copepod Calanus finmarchicus reduce diet-induced obesity and obesity-related metabolic disorders in mice.' (Höper AC et al., 2014).
Transgenic Model
Transgenic Model are used in the study 'Loss of MAP function leads to hippocampal synapse loss and deficits in the Morris Water Maze with aging.' (Ma QL et al., 2014).
Animal Disease Models
Animal Disease Models are used in the study 'Fish oil increases muscle protein mass and modulates Akt/FOXO, TLR4, and NOD signaling in weanling piglets after lipopolysaccharide challenge.' (Liu Y et al., 2013).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with DHA
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Fritsche KL and Cassity NA | Metabolism of [3H]arachidonic acid by n-3 polyunsaturated fatty acid-enriched piglet alveolar macrophages. | 1996 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:8981628 |
| Martin DD et al. | The fatty acid composition of human gliomas differs from that found in nonmalignant brain tissue. | 1996 | Lipids | pmid:8972462 |
| Khalfoun B et al. | Docosahexaenoic and eicosapentaenoic acids inhibit in vitro human lymphocyte-endothelial cell adhesion. | 1996 | Transplantation | pmid:8970622 |
| Brossard N et al. | Metabolic fate of an oral tracer dose of [13C]docosahexaenoic acid triglycerides in the rat. | 1996 | Am. J. Physiol. | pmid:8967415 |
| Futamura Y | Toxicity of amiodarone on mouse pulmonary endothelial cells cultured with or without alveolar macrophages. | 1996 | J Toxicol Sci | pmid:8959650 |
| Foreman-van Drongelen MM et al. | Influence of feeding artificial-formula milks containing docosahexaenoic and arachidonic acids on the postnatal long-chain polyunsaturated fatty acid status of healthy preterm infants. | 1996 | Br. J. Nutr. | pmid:8958000 |
| Garratt JC et al. | Blockade of two voltage-dependent potassium channels, mKv1.1 and mKv1.2, by docosahexaenoic acid. | 1996 | Eur. J. Pharmacol. | pmid:8957264 |
| Ohira T et al. | Improvement by eicosanoids in cancer cachexia induced by LLC-IL6 transplantation. | 1996 | J. Cancer Res. Clin. Oncol. | pmid:8954167 |
| Awad AB et al. | The effect of unsaturated fatty acids on membrane composition and signal transduction in HT-29 human colon cancer cells. | 1996 | Cancer Lett. | pmid:8950205 |
| Reinboth JJ et al. | Light elicits the release of docosahexaenoic acid from membrane phospholipids in the rat retina in vitro. | 1996 | Exp. Eye Res. | pmid:8943700 |
| Katoku Y et al. | Effect of the cholesterol content of a formula on the lipid compositions of plasma lipoproteins and red blood cell membranes in early infancy. | 1996 | Am. J. Clin. Nutr. | pmid:8942411 |
| Suzuki Y et al. | Trial of docosahexaenoic acid supplementation on a Japanese patient with a peroxisome biogenesis defect. | 1996 | Acta Paediatr Jpn | pmid:8942014 |
| Poling JS et al. | Docosahexaenoic acid block of neuronal voltage-gated K+ channels: subunit selective antagonism by zinc. | 1996 | Neuropharmacology | pmid:8938727 |
| Krämer HJ et al. | Fish oil fatty acids and human platelets: dose-dependent decrease in dienoic and increase in trienoic thromboxane generation. | 1996 | Biochem. Pharmacol. | pmid:8937428 |
| De Craemer D et al. | Dietary docosahexaenoic acid has little effect on peroxisomes in healthy mice. | 1996 | Lipids | pmid:8934448 |
| Santos GA and Silversides FG | Utilization of the sex-linked gene for imperfect albinism (S*ALS). 1. Effect of early weight loss on chick metabolism. | 1996 | Poult. Sci. | pmid:8933584 |
| Agren JJ et al. | Fish diet, fish oil and docosahexaenoic acid rich oil lower fasting and postprandial plasma lipid levels. | 1996 | Eur J Clin Nutr | pmid:8933125 |
| Santos FF et al. | Alterations in rabbit retina lipid metabolism induced by detachment. Decreased incorporation of [3H]DHA into phospholipids. | 1995-1996 | Int Ophthalmol | pmid:8926126 |
| Carballeira NM et al. | Phospholipid fatty acid composition of gorgonians of the genus Pseudopterogorgia: identification of tetracosapolyenoic acids. | 1996 | Comp. Biochem. Physiol. B, Biochem. Mol. Biol. | pmid:8925444 |
| Zerouga M et al. | Phospholipid class as a determinant in docosahexaenoic acid's effect on tumor cell viability. | 1996 Sep-Oct | Anticancer Res. | pmid:8917399 |