| MeSH term | MeSH ID | Detail |
|---|---|---|
| Inflammation | D007249 | 119 associated lipids |
| Prostatic Neoplasms | D011471 | 126 associated lipids |
| Cell Transformation, Neoplastic | D002471 | 126 associated lipids |
| Hemolysis | D006461 | 131 associated lipids |
| Carcinoma, Hepatocellular | D006528 | 140 associated lipids |
| Edema | D004487 | 152 associated lipids |
| Colonic Neoplasms | D003110 | 161 associated lipids |
| Adenocarcinoma | D000230 | 166 associated lipids |
| Lung Neoplasms | D008175 | 171 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
DHA
Dha is a lipid of Fatty Acyls (FA) class. Dha is associated with abnormalities such as Atherosclerosis, Consumption-archaic term for TB, Chronic disease, Cardiovascular Diseases and Diabetes Mellitus, Non-Insulin-Dependent. The involved functions are known as Inflammation, Oxidation, fatty acid oxidation, Fatty Acid Metabolism and Lipid Metabolism. Dha often locates in Hepatic, Protoplasm, Mucous Membrane, Epithelium and outer membrane. The associated genes with DHA are IMPACT gene, FATE1 gene, GAPDH gene, THOC4 gene and SLC33A1 gene. The related lipids are stearidonic acid, Fatty Acids, Total cholesterol, Lipopolysaccharides and Dietary Fatty Acid. The related experimental models are Mouse Model, Transgenic Model, Animal Disease Models and Arthritis, Experimental.
Cross Reference
Introduction
To understand associated biological information of DHA, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with DHA?
DHA is suspected in Cardiovascular Diseases, Obesity, Ischemia, Hypertensive disease, Coronary Arteriosclerosis, Cerebrovascular accident and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with DHA
PubChem Associated disorders and diseases
What pathways are associated with DHA
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with DHA?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with DHA?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with DHA?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with DHA?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with DHA?
Mouse Model
Mouse Model are used in the study 'Homeostatic regulation of photoreceptor cell integrity: significance of the potent mediator neuroprotectin D1 biosynthesized from docosahexaenoic acid: the Proctor Lecture.' (Bazan NG, 2007), Mouse Model are used in the study 'Omega-3 fatty acids EPA and DHA: health benefits throughout life.' (Swanson D et al., 2012), Mouse Model are used in the study 'Docosahexaenoic acid attenuates hepatic inflammation, oxidative stress, and fibrosis without decreasing hepatosteatosis in a Ldlr(-/-) mouse model of western diet-induced nonalcoholic steatohepatitis.' (Depner CM et al., 2013) and Mouse Model are used in the study 'Wax esters from the marine copepod Calanus finmarchicus reduce diet-induced obesity and obesity-related metabolic disorders in mice.' (Höper AC et al., 2014).
Transgenic Model
Transgenic Model are used in the study 'Loss of MAP function leads to hippocampal synapse loss and deficits in the Morris Water Maze with aging.' (Ma QL et al., 2014).
Animal Disease Models
Animal Disease Models are used in the study 'Fish oil increases muscle protein mass and modulates Akt/FOXO, TLR4, and NOD signaling in weanling piglets after lipopolysaccharide challenge.' (Liu Y et al., 2013).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
NCBI Entrez Crosslinks
All references with DHA
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Moallem U et al. | Dietary α-linolenic acid from flaxseed oil improved folliculogenesis and IVF performance in dairy cows, similar to eicosapentaenoic and docosahexaenoic acids from fish oil. | 2013 | Reproduction | pmid:24062566 |
| Alessandri JM et al. | Polyunsaturated fatty acids in the central nervous system: evolution of concepts and nutritional implications throughout life. | 2004 Nov-Dec | Reprod. Nutr. Dev. | pmid:15762297 |
| Alessandri JM et al. | Polyunsaturated fatty acids status in blood, heart, liver, intestine, retina and brain of newborn piglets fed either sow milk or a milk replacer diet. | 1996 | Reprod. Nutr. Dev. | pmid:8881596 |
| Lauritzen L et al. | Maternal fish oil supplementation in lactation: effect on developmental outcome in breast-fed infants. | 2005 Sep-Oct | Reprod. Nutr. Dev. | pmid:16188206 |
| Young GS et al. | Effect of randomized supplementation with high dose olive, flax or fish oil on serum phospholipid fatty acid levels in adults with attention deficit hyperactivity disorder. | 2005 Sep-Oct | Reprod. Nutr. Dev. | pmid:16188207 |
| Stillwell W et al. | Docosahexaenoic acid affects cell signaling by altering lipid rafts. | 2005 Sep-Oct | Reprod. Nutr. Dev. | pmid:16188208 |
| Sergeeva M et al. | Regulation of intracellular calcium levels by polyunsaturated fatty acids, arachidonic acid and docosahexaenoic acid, in astrocytes: possible involvement of phospholipase A2. | 2005 Sep-Oct | Reprod. Nutr. Dev. | pmid:16188212 |
| Burdge GC and Calder PC | Conversion of alpha-linolenic acid to longer-chain polyunsaturated fatty acids in human adults. | 2005 Sep-Oct | Reprod. Nutr. Dev. | pmid:16188209 |
| Burdge GC et al. | Docosahexaenoic acid is selectively enriched in plasma phospholipids during pregnancy in Trinidadian women--results of a pilot study. | 2006 Jan-Feb | Reprod. Nutr. Dev. | pmid:16438916 |
| Meher AP et al. | Preconceptional omega-3 fatty acid supplementation on a micronutrient-deficient diet improves the reproductive cycle in Wistar rats. | 2013 | Reprod. Fertil. Dev. | pmid:23137932 |
| Kiernan M et al. | The effect of the in vitro supplementation of exogenous long-chain fatty acids on bovine sperm cell function. | 2013 | Reprod. Fertil. Dev. | pmid:23036717 |
| Kaeoket K et al. | Effect of docosahexaenoic acid on quality of cryopreserved boar semen in different breeds. | 2010 | Reprod. Domest. Anim. | pmid:19090818 |
| Alexopoulos E et al. | Treatment of severe IgA nephropathy with omega-3 fatty acids: the effect of a "very low dose" regimen. | 2004 | Ren Fail | pmid:15462115 |
| Mariee AD and Abd-Ellah MF | Protective effect of docosahexaenoic acid against cyclosporine A-induced nephrotoxicity in rats: a possible mechanism of action. | 2011 | Ren Fail | pmid:21219208 |
| Hammond BG et al. | Safety assessment of DHA-rich microalgae from Schizochytrium sp. | 2002 | Regul. Toxicol. Pharmacol. | pmid:12052009 |
| Abril R et al. | Safety assessment of DHA-rich microalgae from Schizochytrium sp. Part V: target animal safety/toxicity study in growing swine. | 2003 | Regul. Toxicol. Pharmacol. | pmid:12662911 |
| Hammond BG et al. | Safety assessment of DHA-rich microalgae from Schizochytrium sp. | 2001 | Regul. Toxicol. Pharmacol. | pmid:11350202 |
| Hammond BG et al. | Safety assessment of DHA-rich microalgae from Schizochytrium sp. | 2001 | Regul. Toxicol. Pharmacol. | pmid:11350203 |
| Blum R et al. | Genotoxicity and subchronic toxicity studies of DHA-rich oil in rats. | 2007 | Regul. Toxicol. Pharmacol. | pmid:17933446 |
| Blum R et al. | One-generation reproductive toxicity study of DHA-rich oil in rats. | 2007 | Regul. Toxicol. Pharmacol. | pmid:17976878 |