| MeSH term | MeSH ID | Detail |
|---|---|---|
| Inflammation | D007249 | 119 associated lipids |
| Cell Transformation, Neoplastic | D002471 | 126 associated lipids |
| Prostatic Neoplasms | D011471 | 126 associated lipids |
| Hemolysis | D006461 | 131 associated lipids |
| Carcinoma, Hepatocellular | D006528 | 140 associated lipids |
| Edema | D004487 | 152 associated lipids |
| Colonic Neoplasms | D003110 | 161 associated lipids |
| Adenocarcinoma | D000230 | 166 associated lipids |
| Lung Neoplasms | D008175 | 171 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
DHA
Dha is a lipid of Fatty Acyls (FA) class. Dha is associated with abnormalities such as Atherosclerosis, Consumption-archaic term for TB, Chronic disease, Cardiovascular Diseases and Diabetes Mellitus, Non-Insulin-Dependent. The involved functions are known as Inflammation, Oxidation, fatty acid oxidation, Fatty Acid Metabolism and Lipid Metabolism. Dha often locates in Hepatic, Protoplasm, Mucous Membrane, Epithelium and outer membrane. The associated genes with DHA are IMPACT gene, FATE1 gene, GAPDH gene, THOC4 gene and SLC33A1 gene. The related lipids are stearidonic acid, Fatty Acids, Total cholesterol, Lipopolysaccharides and Dietary Fatty Acid. The related experimental models are Mouse Model, Transgenic Model, Animal Disease Models and Arthritis, Experimental.
Cross Reference
Introduction
To understand associated biological information of DHA, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with DHA?
DHA is suspected in Cardiovascular Diseases, Obesity, Ischemia, Hypertensive disease, Coronary Arteriosclerosis, Cerebrovascular accident and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with DHA
PubChem Associated disorders and diseases
What pathways are associated with DHA
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with DHA?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with DHA?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with DHA?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with DHA?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with DHA?
Mouse Model
Mouse Model are used in the study 'Homeostatic regulation of photoreceptor cell integrity: significance of the potent mediator neuroprotectin D1 biosynthesized from docosahexaenoic acid: the Proctor Lecture.' (Bazan NG, 2007), Mouse Model are used in the study 'Omega-3 fatty acids EPA and DHA: health benefits throughout life.' (Swanson D et al., 2012), Mouse Model are used in the study 'Docosahexaenoic acid attenuates hepatic inflammation, oxidative stress, and fibrosis without decreasing hepatosteatosis in a Ldlr(-/-) mouse model of western diet-induced nonalcoholic steatohepatitis.' (Depner CM et al., 2013) and Mouse Model are used in the study 'Wax esters from the marine copepod Calanus finmarchicus reduce diet-induced obesity and obesity-related metabolic disorders in mice.' (Höper AC et al., 2014).
Transgenic Model
Transgenic Model are used in the study 'Loss of MAP function leads to hippocampal synapse loss and deficits in the Morris Water Maze with aging.' (Ma QL et al., 2014).
Animal Disease Models
Animal Disease Models are used in the study 'Fish oil increases muscle protein mass and modulates Akt/FOXO, TLR4, and NOD signaling in weanling piglets after lipopolysaccharide challenge.' (Liu Y et al., 2013).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with DHA
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Li L et al. | Resolvin D1 promotes the interleukin-4-induced alternative activation in BV-2 microglial cells. | 2014 | J Neuroinflammation | pmid:24708771 |
| Chatterjee A et al. | The pro-resolving lipid mediator maresin 1 (MaR1) attenuates inflammatory signaling pathways in vascular smooth muscle and endothelial cells. | 2014 | PLoS ONE | pmid:25409514 |
| Lane K et al. | Bioavailability and potential uses of vegetarian sources of omega-3 fatty acids: a review of the literature. | 2014 | Crit Rev Food Sci Nutr | pmid:24261532 |
| Steffens JP et al. | Testosterone regulates bone response to inflammation. | 2014 | Horm. Metab. Res. | pmid:24526374 |
| Maffei S et al. | Effects of ω-3 PUFAs supplementation on myocardial function and oxidative stress markers in typical Rett syndrome. | 2014 | Mediators Inflamm. | pmid:24526821 |
| Saito H and Ishikawa S | Lipid classes and fatty acid profile of cultured and wild black rockfish, Sebastes schlegeli. | 2014 | J Oleo Sci | pmid:24829130 |
| Yaxin W et al. | Resolvin D1 attenuates lipopolysaccharide induced acute lung injury through CXCL-12/CXCR4 pathway. | 2014 | J. Surg. Res. | pmid:24387839 |
| Leigh NJ et al. | Expression of resolvin D1 biosynthetic pathways in salivary epithelium. | 2014 | J. Dent. Res. | pmid:24389810 |
| O'Connor-Robison CI et al. | The impact of dietary long-chain polyunsaturated fatty acids on bone and cartilage in gilts and sows. | 2014 | J. Anim. Sci. | pmid:25184850 |
| Nakagawa F et al. | 4-Hydroxy hexenal derived from dietary n-3 polyunsaturated fatty acids induces anti-oxidative enzyme heme oxygenase-1 in multiple organs. | 2014 | Biochem. Biophys. Res. Commun. | pmid:24361890 |
| Saito H | Lipid characteristics of five epinephelinae fishes, Epinephelus fasciatus, Epinephelus retouti, Cephalopholis aurantia, Cephalopholis miniatus, and Variola louti, in the Coral Reef. | 2014 | J Oleo Sci | pmid:24717545 |
| Freund Levi Y et al. | Transfer of omega-3 fatty acids across the blood-brain barrier after dietary supplementation with a docosahexaenoic acid-rich omega-3 fatty acid preparation in patients with Alzheimer's disease: the OmegAD study. | 2014 | J. Intern. Med. | pmid:24410954 |
| Russell CD and Schwarze J | The role of pro-resolution lipid mediators in infectious disease. | 2014 | Immunology | pmid:24400794 |
| AlSaleh A et al. | Interaction between a CSK gene variant and fish oil intake influences blood pressure in healthy adults. | 2014 | J. Nutr. | pmid:24401815 |
| Zhao H et al. | Pulmonary delivery of docosahexaenoic acid mitigates bleomycin-induced pulmonary fibrosis. | 2014 | BMC Pulm Med | pmid:24742272 |
| Wu A et al. | Dietary strategy to repair plasma membrane after brain trauma: implications for plasticity and cognition. | 2014 | Neurorehabil Neural Repair | pmid:23911971 |
| Ganesan B et al. | Fortification of foods with omega-3 polyunsaturated fatty acids. | 2014 | Crit Rev Food Sci Nutr | pmid:24188235 |
| Chang G et al. | The relationship of oxygen uptake rate and k(L)a with rheological properties in high cell density cultivation of docosahexaenoic acid by Schizochytrium sp. S31. | 2014 | Bioresour. Technol. | pmid:24292203 |
| Liu L et al. | Higher efficacy of dietary DHA provided as a phospholipid than as a triglyceride for brain DHA accretion in neonatal piglets. | 2014 | J. Lipid Res. | pmid:24470588 |
| de Waal H et al. | The effect of souvenaid on functional brain network organisation in patients with mild Alzheimer's disease: a randomised controlled study. | 2014 | PLoS ONE | pmid:24475144 |