| MeSH term | MeSH ID | Detail |
|---|---|---|
| Inflammation | D007249 | 119 associated lipids |
| Cell Transformation, Neoplastic | D002471 | 126 associated lipids |
| Prostatic Neoplasms | D011471 | 126 associated lipids |
| Hemolysis | D006461 | 131 associated lipids |
| Carcinoma, Hepatocellular | D006528 | 140 associated lipids |
| Edema | D004487 | 152 associated lipids |
| Colonic Neoplasms | D003110 | 161 associated lipids |
| Adenocarcinoma | D000230 | 166 associated lipids |
| Lung Neoplasms | D008175 | 171 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
DHA
Dha is a lipid of Fatty Acyls (FA) class. Dha is associated with abnormalities such as Atherosclerosis, Consumption-archaic term for TB, Chronic disease, Cardiovascular Diseases and Diabetes Mellitus, Non-Insulin-Dependent. The involved functions are known as Inflammation, Oxidation, fatty acid oxidation, Fatty Acid Metabolism and Lipid Metabolism. Dha often locates in Hepatic, Protoplasm, Mucous Membrane, Epithelium and outer membrane. The associated genes with DHA are IMPACT gene, FATE1 gene, GAPDH gene, THOC4 gene and SLC33A1 gene. The related lipids are stearidonic acid, Fatty Acids, Total cholesterol, Lipopolysaccharides and Dietary Fatty Acid. The related experimental models are Mouse Model, Transgenic Model, Animal Disease Models and Arthritis, Experimental.
Cross Reference
Introduction
To understand associated biological information of DHA, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with DHA?
DHA is suspected in Cardiovascular Diseases, Obesity, Ischemia, Hypertensive disease, Coronary Arteriosclerosis, Cerebrovascular accident and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with DHA
PubChem Associated disorders and diseases
What pathways are associated with DHA
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with DHA?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with DHA?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with DHA?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with DHA?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with DHA?
Mouse Model
Mouse Model are used in the study 'Homeostatic regulation of photoreceptor cell integrity: significance of the potent mediator neuroprotectin D1 biosynthesized from docosahexaenoic acid: the Proctor Lecture.' (Bazan NG, 2007), Mouse Model are used in the study 'Omega-3 fatty acids EPA and DHA: health benefits throughout life.' (Swanson D et al., 2012), Mouse Model are used in the study 'Docosahexaenoic acid attenuates hepatic inflammation, oxidative stress, and fibrosis without decreasing hepatosteatosis in a Ldlr(-/-) mouse model of western diet-induced nonalcoholic steatohepatitis.' (Depner CM et al., 2013) and Mouse Model are used in the study 'Wax esters from the marine copepod Calanus finmarchicus reduce diet-induced obesity and obesity-related metabolic disorders in mice.' (Höper AC et al., 2014).
Transgenic Model
Transgenic Model are used in the study 'Loss of MAP function leads to hippocampal synapse loss and deficits in the Morris Water Maze with aging.' (Ma QL et al., 2014).
Animal Disease Models
Animal Disease Models are used in the study 'Fish oil increases muscle protein mass and modulates Akt/FOXO, TLR4, and NOD signaling in weanling piglets after lipopolysaccharide challenge.' (Liu Y et al., 2013).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with DHA
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Litman BJ et al. | The role of docosahexaenoic acid containing phospholipids in modulating G protein-coupled signaling pathways: visual transduction. | 2001 Apr-Jun | J. Mol. Neurosci. | pmid:11478379 |
| Farooqui AA and Horrocks LA | Plasmalogens, phospholipase A2, and docosahexaenoic acid turnover in brain tissue. | 2001 Apr-Jun | J. Mol. Neurosci. | pmid:11478381 |
| Faust PL et al. | The peroxisome deficient PEX2 Zellweger mouse: pathologic and biochemical correlates of lipid dysfunction. | 2001 Apr-Jun | J. Mol. Neurosci. | pmid:11478384 |
| Salem N et al. | Alterations in brain function after loss of docosahexaenoate due to dietary restriction of n-3 fatty acids. | 2001 Apr-Jun | J. Mol. Neurosci. | pmid:11478385 |
| Martinez M | Restoring the DHA levels in the brains of Zellweger patients. | 2001 Apr-Jun | J. Mol. Neurosci. | pmid:11478386 |
| Katz R et al. | Brain uptake and utilization of fatty acids: recommendations for future research. | 2001 Apr-Jun | J. Mol. Neurosci. | pmid:11478387 |
| Watkins PA et al. | Brain uptake and utilization of fatty acids: applications to peroxisomal biogenesis diseases. | 2001 Apr-Jun | J. Mol. Neurosci. | pmid:11478388 |
| Le Petit-Thévenin J et al. | Effects of arachidonic and docosahexaenoic acids on secretion and degradation of bile salt-dependent lipase in AR4-2J cells. | 2001 | J. Lipid Res. | pmid:11483623 |
| Pawlosky RJ et al. | Physiological compartmental analysis of alpha-linolenic acid metabolism in adult humans. | 2001 | J. Lipid Res. | pmid:11483627 |
| O'Connor DL et al. | Growth and development in preterm infants fed long-chain polyunsaturated fatty acids: a prospective, randomized controlled trial. | 2001 | Pediatrics | pmid:11483801 |
| Auestad N et al. | Growth and development in term infants fed long-chain polyunsaturated fatty acids: a double-masked, randomized, parallel, prospective, multivariate study. | 2001 | Pediatrics | pmid:11483802 |
| Pasquier E et al. | Effects of delta5 polyunsaturated fatty acids of maritime pine (Pinus pinaster) seed oil on the fatty acid profile of the developing brain of rats. | 2001 | Lipids | pmid:11485159 |
| Urquhart P et al. | Profile of eicosanoids produced by human saphenous vein endothelial cells and the effect of dietary fatty acids. | 2001 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:11487303 |
| Harris MA et al. | Effects of conjugated linoleic acids and docosahexaenoic acid on rat liver and reproductive tissue fatty acids, prostaglandins and matrix metalloproteinase production. | 2001 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:11487304 |
| Reich EE et al. | Interactions between apolipoprotein E gene and dietary alpha-tocopherol influence cerebral oxidative damage in aged mice. | 2001 | J. Neurosci. | pmid:11487622 |
| Voigt RG et al. | A randomized, double-blind, placebo-controlled trial of docosahexaenoic acid supplementation in children with attention-deficit/hyperactivity disorder. | 2001 | J. Pediatr. | pmid:11487742 |
| Bradley MO et al. | Tumor targeting by conjugation of DHA to paclitaxel. | 2001 | J Control Release | pmid:11489499 |
| Grobas S et al. | Influence of source and percentage of fat added to diet on performance and fatty acid composition of egg yolks of two strains of laying hens. | 2001 | Poult. Sci. | pmid:11495470 |
| Su HM et al. | Peroxisomal straight-chain Acyl-CoA oxidase and D-bifunctional protein are essential for the retroconversion step in docosahexaenoic acid synthesis. | 2001 | J. Biol. Chem. | pmid:11500517 |
| Araya J et al. | Red wine raises plasma HDL and preserves long-chain polyunsaturated fatty acids in rat kidney and erythrocytes. | 2001 | Br. J. Nutr. | pmid:11502232 |