| MeSH term | MeSH ID | Detail |
|---|---|---|
| Precursor T-Cell Lymphoblastic Leukemia-Lymphoma | D054218 | 5 associated lipids |
| Acute Lung Injury | D055371 | 33 associated lipids |
| Geographic Atrophy | D057092 | 1 associated lipids |
| Acute Kidney Injury | D058186 | 34 associated lipids |
| Plaque, Amyloid | D058225 | 19 associated lipids |
| Plaque, Atherosclerotic | D058226 | 7 associated lipids |
| Peripheral Arterial Disease | D058729 | 7 associated lipids |
| Peripheral Nerve Injuries | D059348 | 6 associated lipids |
| Chronic Pain | D059350 | 5 associated lipids |
| Dysbiosis | D064806 | 2 associated lipids |
DHA
Dha is a lipid of Fatty Acyls (FA) class. Dha is associated with abnormalities such as Atherosclerosis, Consumption-archaic term for TB, Chronic disease, Cardiovascular Diseases and Diabetes Mellitus, Non-Insulin-Dependent. The involved functions are known as Inflammation, Oxidation, fatty acid oxidation, Fatty Acid Metabolism and Lipid Metabolism. Dha often locates in Hepatic, Protoplasm, Mucous Membrane, Epithelium and outer membrane. The associated genes with DHA are IMPACT gene, FATE1 gene, GAPDH gene, THOC4 gene and SLC33A1 gene. The related lipids are stearidonic acid, Fatty Acids, Total cholesterol, Lipopolysaccharides and Dietary Fatty Acid. The related experimental models are Mouse Model, Transgenic Model, Animal Disease Models and Arthritis, Experimental.
Cross Reference
Introduction
To understand associated biological information of DHA, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with DHA?
DHA is suspected in Cardiovascular Diseases, Obesity, Ischemia, Hypertensive disease, Coronary Arteriosclerosis, Cerebrovascular accident and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with DHA
PubChem Associated disorders and diseases
What pathways are associated with DHA
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with DHA?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with DHA?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with DHA?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with DHA?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with DHA?
Mouse Model
Mouse Model are used in the study 'Homeostatic regulation of photoreceptor cell integrity: significance of the potent mediator neuroprotectin D1 biosynthesized from docosahexaenoic acid: the Proctor Lecture.' (Bazan NG, 2007), Mouse Model are used in the study 'Omega-3 fatty acids EPA and DHA: health benefits throughout life.' (Swanson D et al., 2012), Mouse Model are used in the study 'Docosahexaenoic acid attenuates hepatic inflammation, oxidative stress, and fibrosis without decreasing hepatosteatosis in a Ldlr(-/-) mouse model of western diet-induced nonalcoholic steatohepatitis.' (Depner CM et al., 2013) and Mouse Model are used in the study 'Wax esters from the marine copepod Calanus finmarchicus reduce diet-induced obesity and obesity-related metabolic disorders in mice.' (Höper AC et al., 2014).
Transgenic Model
Transgenic Model are used in the study 'Loss of MAP function leads to hippocampal synapse loss and deficits in the Morris Water Maze with aging.' (Ma QL et al., 2014).
Animal Disease Models
Animal Disease Models are used in the study 'Fish oil increases muscle protein mass and modulates Akt/FOXO, TLR4, and NOD signaling in weanling piglets after lipopolysaccharide challenge.' (Liu Y et al., 2013).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with DHA
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| de Urquiza AM et al. | Docosahexaenoic acid, a ligand for the retinoid X receptor in mouse brain. | 2000 | Science | pmid:11118147 |
| Stockard JE et al. | Effect of docosahexaenoic acid content of maternal diet on auditory brainstem conduction times in rat pups. | 2000 Sep-Dec | Dev. Neurosci. | pmid:11111168 |
| Innis SM | The role of dietary n-6 and n-3 fatty acids in the developing brain. | 2000 Sep-Dec | Dev. Neurosci. | pmid:11111165 |
| Auestad N | Infant nutrition--brain development--disease in later life. An introduction. | 2000 Sep-Dec | Dev. Neurosci. | pmid:11111164 |
| Song JH et al. | Polyunsaturated (n-3) fatty acids susceptible to peroxidation are increased in plasma and tissue lipids of rats fed docosahexaenoic acid-containing oils. | 2000 | J. Nutr. | pmid:11110863 |
| Mezzano D et al. | Cardiovascular risk factors in vegetarians. Normalization of hyperhomocysteinemia with vitamin B(12) and reduction of platelet aggregation with n-3 fatty acids. | 2000 | Thromb. Res. | pmid:11108902 |
| Baldessarini RJ et al. | Fatty acid derivatives of clozapine: prolonged antidopaminergic activity of docosahexaenoylclozapine in the rat. | 2001 | Neuropsychopharmacology | pmid:11106876 |
| Decsi T et al. | Fatty acid composition of human milk in Hungary. | 2000 | Acta Paediatr. | pmid:11106060 |
| Ikemoto A et al. | Effect of n-3 fatty acid deficiency on fatty acid composition and metabolism of aminophospholipids in rat brain synaptosomes. | 2000 | Lipids | pmid:11104017 |
| Wang M et al. | Induction of mammary differentiation by mammary-derived growth inhibitor-related gene that interacts with an omega-3 fatty acid on growth inhibition of breast cancer cells. | 2000 | Cancer Res. | pmid:11103817 |
| Lapillonne A et al. | The use of low-EPA fish oil for long-chain polyunsaturated fatty acid supplementation of preterm infants. | 2000 | Pediatr. Res. | pmid:11102555 |
| Freedman SD et al. | Fatty acids in cystic fibrosis. | 2000 | Curr Opin Pulm Med | pmid:11100964 |
| Rissanen T et al. | Fish oil-derived fatty acids, docosahexaenoic acid and docosapentaenoic acid, and the risk of acute coronary events: the Kuopio ischaemic heart disease risk factor study. | 2000 | Circulation | pmid:11094031 |
| Otto SJ et al. | The effect of supplementation with docosahexaenoic and arachidonic acid derived from single cell oils on plasma and erythrocyte fatty acids of pregnant women in the second trimester. | 2000 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:11090260 |
| Chen ZY and Istfan NW | Docosahexaenoic acid is a potent inducer of apoptosis in HT-29 colon cancer cells. | 2000 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:11090257 |
| Fokkema MR et al. | Short-term supplementation of low-dose gamma-linolenic acid (GLA), alpha-linolenic acid (ALA), or GLA plus ALA does not augment LCP omega 3 status of Dutch vegans to an appreciable extent. | 2000 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:11090255 |
| Louw L and Dannhauser A | Keloids in rural black South Africans. Part 2: dietary fatty acid intake and total phospholipid fatty acid profile in the blood of keloid patients. | 2000 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:11090250 |
| Diep QN et al. | Docosahexaenoic acid, a peroxisome proliferator-activated receptor-alpha ligand, induces apoptosis in vascular smooth muscle cells by stimulation of p38 mitogen-activated protein kinase. | 2000 | Hypertension | pmid:11082155 |
| Moriguchi T et al. | Behavioral deficits associated with dietary induction of decreased brain docosahexaenoic acid concentration. | 2000 | J. Neurochem. | pmid:11080210 |
| Contreras MA et al. | Nutritional deprivation of alpha-linolenic acid decreases but does not abolish turnover and availability of unacylated docosahexaenoic acid and docosahexaenoyl-CoA in rat brain. | 2000 | J. Neurochem. | pmid:11080190 |
| Totland GK et al. | Proliferation of mitochondria and gene expression of carnitine palmitoyltransferase and fatty acyl-CoA oxidase in rat skeletal muscle, heart and liver by hypolipidemic fatty acids. | 2000 | Biol. Cell | pmid:11071041 |
| Lim SY and Suzuki H | Effect of dietary docosahexaenoic acid and phosphatidylcholine on maze behavior and fatty acid composition of plasma and brain lipids in mice. | 2000 | Int J Vitam Nutr Res | pmid:11068705 |
| Lopez-Alarcon M et al. | Illness-induced anorexia in the breast-fed infants. Role of IL-1beta and TNF-alpha. | 2000 | Adv. Exp. Med. Biol. | pmid:11065112 |
| Decsi T et al. | Low contribution of docosahexaenoic acid to the fatty acid composition of mature human milk in Hungary. | 2000 | Adv. Exp. Med. Biol. | pmid:11065108 |
| Savino F et al. | Arachidonic (AA) and docosahexaenoic (DHA) acid content in healthy infants fed with an HA milk formula supplemented with LCPUFA and in breast fed infants. | 2000 | Adv. Exp. Med. Biol. | pmid:11065107 |
| Lauritizen L et al. | Dietary fish and the docosahexaenoic acid (DHA) content of human milk. | 2000 | Adv. Exp. Med. Biol. | pmid:11065103 |
| Smit EN et al. | Docosahexaenoic acid (DHA) status of breastfed malnourished infants and their mothers in North Pakistan. | 2000 | Adv. Exp. Med. Biol. | pmid:11065099 |
| Granot E et al. | Breast-fed and formula-fed infants do not differ in immunocompetent cell cytokine production despite differences in cell membrane fatty acid composition. | 2000 | Am. J. Clin. Nutr. | pmid:11063450 |
| Sherman MP | Human milk, fatty acids, and the immune response: a new glimpse. | 2000 | Am. J. Clin. Nutr. | pmid:11063429 |
| Salem ML et al. | N-3 polyunsaturated fatty acids accentuate B16 melanoma growth and metastasis through suppression of tumoricidal function of T cells and macrophages. | 2000 Sep-Oct | Anticancer Res. | pmid:11062743 |
| Pakala R et al. | Vascular smooth muscle cells preloaded with eicosapentaenoic acid and docosahexaenoic acid fail to respond to serotonin stimulation. | 2000 | Atherosclerosis | pmid:11058699 |
| Surai PF et al. | Effect of long-term supplementation with arachidonic or docosahexaenoic acids on sperm production in the broiler chicken. | 2000 | J. Reprod. Fertil. | pmid:11058441 |
| Hosokawa M et al. | Conversion to docosahexaenoic acid-containing phosphatidylserine from squid skin lecithin by phospholipase D-mediated transphosphatidylation. | 2000 | J. Agric. Food Chem. | pmid:11052698 |
| Gerber MJ et al. | Profiles of a healthful diet and its relationship to biomarkers in a population sample from Mediterranean southern France. | 2000 | J Am Diet Assoc | pmid:11043701 |
| Garcia HS et al. | Synthesis of glycerides containing n-3 fatty acids and conjugated linoleic acid by solvent-free acidolysis of fish oil. | 2000 | Biotechnol. Bioeng. | pmid:11042555 |
| Luquain C et al. | Bis(monoacylglycerol) phosphate in rat uterine stromal cells: structural characterization and specific esterification of docosahexaenoic acid. | 2000 | Biochem. J. | pmid:11042136 |
| Arterburn LM et al. | In vitro genotoxicity testing of ARASCO and DHASCO oils. | 2000 | Food Chem. Toxicol. | pmid:11038233 |
| Jenski LJ et al. | Docosahexaenoic acid-containing phosphatidylcholine affects the binding of monoclonal antibodies to purified Kb reconstituted into liposomes. | 2000 | Biochim. Biophys. Acta | pmid:11030589 |
| House S | Stages in reproduction particularly vulnerable to xenobiotic hazards and nutritional deficits. | 2000 | Nutr Health | pmid:11028931 |
| Qian SY et al. | EPR detection of lipid-derived free radicals from PUFA, LDL, and cell oxidations. | 2000 | Free Radic. Biol. Med. | pmid:11025200 |
| Glozman S et al. | Docosahexaenoic acid-deficient phosphatidyl serine and high alpha-tocopherol in a fetal mouse brain over-expressing Cu/Zn-superoxide dismutase. | 2000 | Biochim. Biophys. Acta | pmid:11018466 |
| Favrelère S et al. | Age-related changes in ethanolamine glycerophospholipid fatty acid levels in rat frontal cortex and hippocampus. | 2000 Sep-Oct | Neurobiol. Aging | pmid:11016534 |
| Petrik MB et al. | Highly unsaturated (n-3) fatty acids, but not alpha-linolenic, conjugated linoleic or gamma-linolenic acids, reduce tumorigenesis in Apc(Min/+) mice. | 2000 | J. Nutr. | pmid:11015469 |
| MartÃnez-Cayuela M et al. | Metabolism of palmitic and docosahexaenoic acids in Reuber H35 hepatoma cells. | 2000 | J. Biochem. | pmid:11011136 |
| Xi S et al. | 15-hydroxyeicosatrienoic acid (15-HETrE) suppresses epidermal hyperproliferation via the modulation of nuclear transcription factor (AP-1) and apoptosis. | 2000 | Arch. Dermatol. Res. | pmid:10994774 |
| Cunnane SC | Commentary on the workshop statement. Essentiality of and recommended dietary intakes for Omega-6 and Omega-3 fatty acids. | 2000 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:10991770 |
| Wijendran V et al. | Fetal erythrocyte phospholipid polyunsaturated fatty acids are altered in pregnancy complicated with gestational diabetes mellitus. | 2000 | Lipids | pmid:10984116 |
| Hamilton L et al. | n-3 fatty acid deficiency decreases phosphatidylserine accumulation selectively in neuronal tissues. | 2000 | Lipids | pmid:10984109 |
| Hsu FF et al. | Electrospray ionization mass spectrometric analyses of changes in tissue phospholipid molecular species during the evolution of hyperlipidemia and hyperglycemia in Zucker diabetic fatty rats. | 2000 | Lipids | pmid:10984107 |
| Mori TA et al. | Differential effects of eicosapentaenoic acid and docosahexaenoic acid on vascular reactivity of the forearm microcirculation in hyperlipidemic, overweight men. | 2000 | Circulation | pmid:10982541 |