DHA

Dha is a lipid of Fatty Acyls (FA) class. Dha is associated with abnormalities such as Atherosclerosis, Consumption-archaic term for TB, Chronic disease, Cardiovascular Diseases and Diabetes Mellitus, Non-Insulin-Dependent. The involved functions are known as Inflammation, Oxidation, fatty acid oxidation, Fatty Acid Metabolism and Lipid Metabolism. Dha often locates in Hepatic, Protoplasm, Mucous Membrane, Epithelium and outer membrane. The associated genes with DHA are IMPACT gene, FATE1 gene, GAPDH gene, THOC4 gene and SLC33A1 gene. The related lipids are stearidonic acid, Fatty Acids, Total cholesterol, Lipopolysaccharides and Dietary Fatty Acid. The related experimental models are Mouse Model, Transgenic Model, Animal Disease Models and Arthritis, Experimental.

Cross Reference

Introduction

To understand associated biological information of DHA, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with DHA?

DHA is suspected in Cardiovascular Diseases, Obesity, Ischemia, Hypertensive disease, Coronary Arteriosclerosis, Cerebrovascular accident and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with DHA

MeSH term MeSH ID Detail
Trophoblastic Tumor, Placental Site D018245 1 associated lipids
Phenylketonuria, Maternal D017042 1 associated lipids
Refsum Disease, Infantile D052919 1 associated lipids
Pulmonary Valve Stenosis D011666 1 associated lipids
Cerebrovascular Trauma D020214 1 associated lipids
Histiocytoma, Malignant Fibrous D051677 1 associated lipids
Decapitation D049248 2 associated lipids
Communication Disorders D003147 1 associated lipids
Geographic Atrophy D057092 1 associated lipids
Lordosis D008141 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with DHA

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with DHA?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with DHA?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with DHA?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with DHA?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with DHA?

Mouse Model

Mouse Model are used in the study 'Homeostatic regulation of photoreceptor cell integrity: significance of the potent mediator neuroprotectin D1 biosynthesized from docosahexaenoic acid: the Proctor Lecture.' (Bazan NG, 2007), Mouse Model are used in the study 'Omega-3 fatty acids EPA and DHA: health benefits throughout life.' (Swanson D et al., 2012), Mouse Model are used in the study 'Docosahexaenoic acid attenuates hepatic inflammation, oxidative stress, and fibrosis without decreasing hepatosteatosis in a Ldlr(-/-) mouse model of western diet-induced nonalcoholic steatohepatitis.' (Depner CM et al., 2013) and Mouse Model are used in the study 'Wax esters from the marine copepod Calanus finmarchicus reduce diet-induced obesity and obesity-related metabolic disorders in mice.' (Höper AC et al., 2014).

Transgenic Model

Transgenic Model are used in the study 'Loss of MAP function leads to hippocampal synapse loss and deficits in the Morris Water Maze with aging.' (Ma QL et al., 2014).

Animal Disease Models

Animal Disease Models are used in the study 'Fish oil increases muscle protein mass and modulates Akt/FOXO, TLR4, and NOD signaling in weanling piglets after lipopolysaccharide challenge.' (Liu Y et al., 2013).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with DHA

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Authors Title Published Journal PubMed Link
Bakker EC et al. Early nutrition, essential fatty acid status and visual acuity of term infants at 7 months of age. 1999 Eur J Clin Nutr pmid:10557000
Elmore JS et al. Effect of the polyunsaturated fatty acid composition of beef muscle on the profile of aroma volatiles. 1999 J. Agric. Food Chem. pmid:10564028
Purepa. 1999 Drugs R D pmid:10566043
Agostoni C et al. Long-chain polyunsaturated fatty acids in human milk. 1999 Acta Paediatr Suppl pmid:10569226
Freedman SD et al. A membrane lipid imbalance plays a role in the phenotypic expression of cystic fibrosis in cftr(-/-) mice. 1999 Proc. Natl. Acad. Sci. U.S.A. pmid:10570187
Madsen L et al. Eicosapentaenoic and docosahexaenoic acid affect mitochondrial and peroxisomal fatty acid oxidation in relation to substrate preference. 1999 Lipids pmid:10574660
Yoshida H et al. Effect of dietary seal and fish oils on triacylglycerol metabolism in rats. 1999 J. Nutr. Sci. Vitaminol. pmid:10575632
Bisogno T et al. Biosynthesis and inactivation of N-arachidonoylethanolamine (anandamide) and N-docosahexaenoylethanolamine in bovine retina. 1999 Arch. Biochem. Biophys. pmid:10577359
Jørgensen MH et al. Does human milk DHA level affect functional outcome in infants? 1999 J Hum Lact pmid:10578769
Samples BL et al. Polyunsaturated fatty acids enhance the heat induced stress response in rainbow trout (Oncorhynchus mykiss) leukocytes. 1999 Comp. Biochem. Physiol. B, Biochem. Mol. Biol. pmid:10582313
Norrish AE et al. Prostate cancer risk and consumption of fish oils: a dietary biomarker-based case-control study. 1999 Br. J. Cancer pmid:10584888
Conquer JA et al. Effect of supplementation with dietary seal oil on selected cardiovascular risk factors and hemostatic variables in healthy male subjects. 1999 Thromb. Res. pmid:10588467
Levy R and Herzberg GR Hydrolysis of long-chain, n-3 fatty acid enriched chylomicrons by cardiac lipoprotein lipase. 1999 Can. J. Physiol. Pharmacol. pmid:10588486
Senkal M et al. Outcome and cost-effectiveness of perioperative enteral immunonutrition in patients undergoing elective upper gastrointestinal tract surgery: a prospective randomized study. 1999 Arch Surg pmid:10593328
LeVine SM et al. Microchemical analysis of retina layers in pigmented and albino rats by Fourier transform infrared microspectroscopy. 1999 Biochim. Biophys. Acta pmid:10594378
Kageyama K et al. Cytotoxicity of docosahexaenoic acid and eicosapentaenoic acid in tumor cells and the dependence on binding to serum proteins and incorporation into intracellular lipids. 2000 Jan-Feb Oncol. Rep. pmid:10601596
Miyazaki M et al. Dietary docosahexaenoic acid ameliorates, but rapeseed oil and safflower oil accelerate renal injury in stroke-prone spontaneously hypertensive rats as compared with soybean oil, which is associated with expression for renal transforming growth factor-beta, fibronectin and renin. 2000 Biochim. Biophys. Acta pmid:10601699
Retterstøl K et al. The pathway from arachidonic to docosapentaenoic acid (20:4n-6 to 22:5n-6) and from eicosapentaenoic to docosahexaenoic acid (20:5n-3 to 22:6n-3) studied in testicular cells from immature rats. 2000 Biochim. Biophys. Acta pmid:10601701
Nitsan Z et al. Enrichment of poultry products with omega3 fatty acids by dietary supplementation with the alga Nannochloropsis and mantur oil. 1999 J. Agric. Food Chem. pmid:10606584
McGahon BM et al. Age-related changes in synaptic function: analysis of the effect of dietary supplementation with omega-3 fatty acids. 1999 Neuroscience pmid:10613520