DHA

Dha is a lipid of Fatty Acyls (FA) class. Dha is associated with abnormalities such as Atherosclerosis, Consumption-archaic term for TB, Chronic disease, Cardiovascular Diseases and Diabetes Mellitus, Non-Insulin-Dependent. The involved functions are known as Inflammation, Oxidation, fatty acid oxidation, Fatty Acid Metabolism and Lipid Metabolism. Dha often locates in Hepatic, Protoplasm, Mucous Membrane, Epithelium and outer membrane. The associated genes with DHA are IMPACT gene, FATE1 gene, GAPDH gene, THOC4 gene and SLC33A1 gene. The related lipids are stearidonic acid, Fatty Acids, Total cholesterol, Lipopolysaccharides and Dietary Fatty Acid. The related experimental models are Mouse Model, Transgenic Model, Animal Disease Models and Arthritis, Experimental.

Cross Reference

Introduction

To understand associated biological information of DHA, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with DHA?

DHA is suspected in Cardiovascular Diseases, Obesity, Ischemia, Hypertensive disease, Coronary Arteriosclerosis, Cerebrovascular accident and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with DHA

MeSH term MeSH ID Detail
Trophoblastic Tumor, Placental Site D018245 1 associated lipids
Phenylketonuria, Maternal D017042 1 associated lipids
Refsum Disease, Infantile D052919 1 associated lipids
Pulmonary Valve Stenosis D011666 1 associated lipids
Cerebrovascular Trauma D020214 1 associated lipids
Histiocytoma, Malignant Fibrous D051677 1 associated lipids
Decapitation D049248 2 associated lipids
Communication Disorders D003147 1 associated lipids
Geographic Atrophy D057092 1 associated lipids
Lordosis D008141 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with DHA

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with DHA?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with DHA?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with DHA?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with DHA?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with DHA?

Mouse Model

Mouse Model are used in the study 'Homeostatic regulation of photoreceptor cell integrity: significance of the potent mediator neuroprotectin D1 biosynthesized from docosahexaenoic acid: the Proctor Lecture.' (Bazan NG, 2007), Mouse Model are used in the study 'Omega-3 fatty acids EPA and DHA: health benefits throughout life.' (Swanson D et al., 2012), Mouse Model are used in the study 'Docosahexaenoic acid attenuates hepatic inflammation, oxidative stress, and fibrosis without decreasing hepatosteatosis in a Ldlr(-/-) mouse model of western diet-induced nonalcoholic steatohepatitis.' (Depner CM et al., 2013) and Mouse Model are used in the study 'Wax esters from the marine copepod Calanus finmarchicus reduce diet-induced obesity and obesity-related metabolic disorders in mice.' (Höper AC et al., 2014).

Transgenic Model

Transgenic Model are used in the study 'Loss of MAP function leads to hippocampal synapse loss and deficits in the Morris Water Maze with aging.' (Ma QL et al., 2014).

Animal Disease Models

Animal Disease Models are used in the study 'Fish oil increases muscle protein mass and modulates Akt/FOXO, TLR4, and NOD signaling in weanling piglets after lipopolysaccharide challenge.' (Liu Y et al., 2013).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with DHA

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Authors Title Published Journal PubMed Link
Ghebremeskel K et al. Maternal diet high in fat reduces docosahexaenoic acid in liver lipids of newborn and sucking rat pups. 1999 Br. J. Nutr. pmid:10615212
Makrides M et al. A critical appraisal of the role of dietary long-chain polyunsaturated fatty acids on neural indices of term infants: a randomized, controlled trial. 2000 Pediatrics pmid:10617701
Tolley EA and Carlson SE Considerations of statistical power in infant studies of visual acuity development and docosahexaenoic acid status. 2000 Am. J. Clin. Nutr. pmid:10617938
Connor SL et al. Cheek cell phospholipids in human infants: a marker of docosahexaenoic and arachidonic acids in the diet, plasma, and red blood cells. 2000 Am. J. Clin. Nutr. pmid:10617942
Connor WE Importance of n-3 fatty acids in health and disease. 2000 Am. J. Clin. Nutr. pmid:10617967
Innis SM Essential fatty acids in infant nutrition: lessons and limitations from animal studies in relation to studies on infant fatty acid requirements. 2000 Am. J. Clin. Nutr. pmid:10617978
Neuringer M Infant vision and retinal function in studies of dietary long-chain polyunsaturated fatty acids: methods, results, and implications. 2000 Am. J. Clin. Nutr. pmid:10617981
Carlson SE Behavioral methods used in the study of long-chain polyunsaturated fatty acid nutrition in primate infants. 2000 Am. J. Clin. Nutr. pmid:10617982
Crawford M Placental delivery of arachidonic and docosahexaenoic acids: implications for the lipid nutrition of preterm infants. 2000 Am. J. Clin. Nutr. pmid:10617983
Al MD et al. Long-chain polyunsaturated fatty acids, pregnancy, and pregnancy outcome. 2000 Am. J. Clin. Nutr. pmid:10617984
Jensen CL et al. Effect of docosahexaenoic acid supplementation of lactating women on the fatty acid composition of breast milk lipids and maternal and infant plasma phospholipids. 2000 Am. J. Clin. Nutr. pmid:10617985
Makrides M and Gibson RA Long-chain polyunsaturated fatty acid requirements during pregnancy and lactation. 2000 Am. J. Clin. Nutr. pmid:10617987
Auestad N and Innis SM Dietary n-3 fatty acid restriction during gestation in rats: neuronal cell body and growth-cone fatty acids. 2000 Am. J. Clin. Nutr. pmid:10617988
Dutta-Roy AK Transport mechanisms for long-chain polyunsaturated fatty acids in the human placenta. 2000 Am. J. Clin. Nutr. pmid:10617989
Stordy BJ Dark adaptation, motor skills, docosahexaenoic acid, and dyslexia. 2000 Am. J. Clin. Nutr. pmid:10617990
Burgess JR et al. Long-chain polyunsaturated fatty acids in children with attention-deficit hyperactivity disorder. 2000 Am. J. Clin. Nutr. pmid:10617991
James MJ et al. Dietary polyunsaturated fatty acids and inflammatory mediator production. 2000 Am. J. Clin. Nutr. pmid:10617994
Kremer JM n-3 fatty acid supplements in rheumatoid arthritis. 2000 Am. J. Clin. Nutr. pmid:10617995
Hughes DA and Pinder AC n-3 polyunsaturated fatty acids inhibit the antigen-presenting function of human monocytes. 2000 Am. J. Clin. Nutr. pmid:10617997
Ziboh VA et al. Metabolism of polyunsaturated fatty acids by skin epidermal enzymes: generation of antiinflammatory and antiproliferative metabolites. 2000 Am. J. Clin. Nutr. pmid:10617998