| MeSH term | MeSH ID | Detail |
|---|---|---|
| Trophoblastic Tumor, Placental Site | D018245 | 1 associated lipids |
| Phenylketonuria, Maternal | D017042 | 1 associated lipids |
| Refsum Disease, Infantile | D052919 | 1 associated lipids |
| Pulmonary Valve Stenosis | D011666 | 1 associated lipids |
| Cerebrovascular Trauma | D020214 | 1 associated lipids |
| Histiocytoma, Malignant Fibrous | D051677 | 1 associated lipids |
| Decapitation | D049248 | 2 associated lipids |
| Communication Disorders | D003147 | 1 associated lipids |
| Geographic Atrophy | D057092 | 1 associated lipids |
| Lordosis | D008141 | 1 associated lipids |
DHA
Dha is a lipid of Fatty Acyls (FA) class. Dha is associated with abnormalities such as Atherosclerosis, Consumption-archaic term for TB, Chronic disease, Cardiovascular Diseases and Diabetes Mellitus, Non-Insulin-Dependent. The involved functions are known as Inflammation, Oxidation, fatty acid oxidation, Fatty Acid Metabolism and Lipid Metabolism. Dha often locates in Hepatic, Protoplasm, Mucous Membrane, Epithelium and outer membrane. The associated genes with DHA are IMPACT gene, FATE1 gene, GAPDH gene, THOC4 gene and SLC33A1 gene. The related lipids are stearidonic acid, Fatty Acids, Total cholesterol, Lipopolysaccharides and Dietary Fatty Acid. The related experimental models are Mouse Model, Transgenic Model, Animal Disease Models and Arthritis, Experimental.
Cross Reference
Introduction
To understand associated biological information of DHA, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with DHA?
DHA is suspected in Cardiovascular Diseases, Obesity, Ischemia, Hypertensive disease, Coronary Arteriosclerosis, Cerebrovascular accident and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with DHA
PubChem Associated disorders and diseases
What pathways are associated with DHA
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with DHA?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with DHA?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with DHA?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with DHA?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with DHA?
Mouse Model
Mouse Model are used in the study 'Homeostatic regulation of photoreceptor cell integrity: significance of the potent mediator neuroprotectin D1 biosynthesized from docosahexaenoic acid: the Proctor Lecture.' (Bazan NG, 2007), Mouse Model are used in the study 'Omega-3 fatty acids EPA and DHA: health benefits throughout life.' (Swanson D et al., 2012), Mouse Model are used in the study 'Docosahexaenoic acid attenuates hepatic inflammation, oxidative stress, and fibrosis without decreasing hepatosteatosis in a Ldlr(-/-) mouse model of western diet-induced nonalcoholic steatohepatitis.' (Depner CM et al., 2013) and Mouse Model are used in the study 'Wax esters from the marine copepod Calanus finmarchicus reduce diet-induced obesity and obesity-related metabolic disorders in mice.' (Höper AC et al., 2014).
Transgenic Model
Transgenic Model are used in the study 'Loss of MAP function leads to hippocampal synapse loss and deficits in the Morris Water Maze with aging.' (Ma QL et al., 2014).
Animal Disease Models
Animal Disease Models are used in the study 'Fish oil increases muscle protein mass and modulates Akt/FOXO, TLR4, and NOD signaling in weanling piglets after lipopolysaccharide challenge.' (Liu Y et al., 2013).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with DHA
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Soubias O and Gawrisch K | Rhodopsin-lipid interactions studied by NMR. | 2013 | Meth. Enzymol. | pmid:23374188 |
| Ishida T et al. | Distinct regulation of plasma LDL cholesterol by eicosapentaenoic acid and docosahexaenoic acid in high fat diet-fed hamsters: participation of cholesterol ester transfer protein and LDL receptor. | 2013 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:23375839 |
| Milic I et al. | Simultaneous detection of low and high molecular weight carbonylated compounds derived from lipid peroxidation by electrospray ionization-tandem mass spectrometry. | 2013 | Anal. Chem. | pmid:23186270 |
| Xu J et al. | Expression of a type 2 diacylglycerol acyltransferase from Thalassiosira pseudonana in yeast leads to incorporation of docosahexaenoic acid β-oxidation intermediates into triacylglycerol. | 2013 | FEBS J. | pmid:24128189 |
| Kimura R et al. | DHA attenuates postprandial hyperlipidemia via activating PPARα in intestinal epithelial cells. | 2013 | J. Lipid Res. | pmid:24133194 |
| Rovito D et al. | Omega-3 PUFA ethanolamides DHEA and EPEA induce autophagy through PPARγ activation in MCF-7 breast cancer cells. | 2013 | J. Cell. Physiol. | pmid:23168911 |
| Sato SB et al. | Inhibition of constitutive Akt (PKB) phosphorylation by docosahexaenoic acid in the human breast cancer cell line MDA-MB-453. | 2013 | Biochim. Biophys. Acta | pmid:23085420 |
| Faizan M et al. | Dietary alpha-tocopherol affects tissue vitamin e and malondialdehyde levels but does not change antioxidant enzymes and fatty acid composition in farmed Atlantic salmon (Salmo salar L.). | 2013 | Int J Vitam Nutr Res | pmid:25008014 |
| Al-Taan O et al. | Changes in plasma and erythrocyte omega-6 and omega-3 fatty acids in response to intravenous supply of omega-3 fatty acids in patients with hepatic colorectal metastases. | 2013 | Lipids Health Dis | pmid:23648075 |
| Marze S et al. | In vitro digestion of fish oils rich in n-3 polyunsaturated fatty acids studied in emulsion and at the oil-water interface. | 2013 | Food Funct | pmid:23086175 |
| Liu J et al. | Screening and characterization of Isochrysis strains and optimization of culture conditions for docosahexaenoic acid production. | 2013 | Appl. Microbiol. Biotechnol. | pmid:23423326 |
| Metherel AH et al. | Butylated hydroxytoluene can protect polyunsaturated fatty acids in dried blood spots from degradation for up to 8 weeks at room temperature. | 2013 | Lipids Health Dis | pmid:23425563 |
| Carlson SE et al. | DHA supplementation and pregnancy outcomes. | 2013 | Am. J. Clin. Nutr. | pmid:23426033 |
| Mozaffari-Khosravi H et al. | Eicosapentaenoic acid versus docosahexaenoic acid in mild-to-moderate depression: a randomized, double-blind, placebo-controlled trial. | 2013 | Eur Neuropsychopharmacol | pmid:22910528 |
| Cardenia V et al. | Health-related lipids components of sardine muscle as affected by photooxidation. | 2013 | Food Chem. Toxicol. | pmid:23500769 |
| Dalli J et al. | The novel 13S,14S-epoxy-maresin is converted by human macrophages to maresin 1 (MaR1), inhibits leukotriene A4 hydrolase (LTA4H), and shifts macrophage phenotype. | 2013 | FASEB J. | pmid:23504711 |
| Mickleborough TD | Omega-3 polyunsaturated fatty acids in physical performance optimization. | 2013 | Int J Sport Nutr Exerc Metab | pmid:23400626 |
| Bagley HN et al. | Maternal docosahexaenoic acid increases adiponectin and normalizes IUGR-induced changes in rat adipose deposition. | 2013 | J Obes | pmid:23533720 |
| Dangour AD and Allen E | Do omega-3 fats boost brain function in adults? Are we any closer to an answer? | 2013 | Am. J. Clin. Nutr. | pmid:23535110 |
| Miller E et al. | A short-term n-3 DPA supplementation study in humans. | 2013 | Eur J Nutr | pmid:22729967 |
| Ribeiro T et al. | Direct supplementation of diet is the most efficient way of enriching broiler meat with n-3 long-chain polyunsaturated fatty acids. | 2013 | Br. Poult. Sci. | pmid:24397512 |
| Singh A et al. | Gene-metabolite expression in blood can discriminate allergen-induced isolated early from dual asthmatic responses. | 2013 | PLoS ONE | pmid:23844124 |
| Muldoon MF et al. | Concurrent physical activity modifies the association between n3 long-chain fatty acids and cardiometabolic risk in midlife adults. | 2013 | J. Nutr. | pmid:23884386 |
| Watson AM et al. | Taurine supplementation of plant derived protein and n-3 fatty acids are critical for optimal growth and development of cobia, Rachycentron canadum. | 2013 | Lipids | pmid:23884630 |
| Rayapudi S et al. | Vitamin A and fish oils for retinitis pigmentosa. | 2013 | Cochrane Database Syst Rev | pmid:24357340 |
| Nyuar KB et al. | Regular consumption of Nile river fish could ameliorate the low milk DHA of Southern Sudanese women living in Khartoum City area. | 2013 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:23706881 |
| Terrando N et al. | Aspirin-triggered resolvin D1 prevents surgery-induced cognitive decline. | 2013 | FASEB J. | pmid:23709617 |
| Fietkau R et al. | A disease-specific enteral nutrition formula improves nutritional status and functional performance in patients with head and neck and esophageal cancer undergoing chemoradiotherapy: results of a randomized, controlled, multicenter trial. | 2013 | Cancer | pmid:23765693 |
| Alhazzaa R et al. | Bioconversion of α-linolenic acid into n-3 long-chain polyunsaturated fatty acid in hepatocytes and ad hoc cell culture optimisation. | 2013 | PLoS ONE | pmid:24040040 |
| Laird BD et al. | Dietary advice on Inuit traditional food use needs to balance benefits and risks of mercury, selenium, and n3 fatty acids. | 2013 | J. Nutr. | pmid:23616502 |
| Sala-Vila A et al. | Eicosapentaenoic acid in serum phospholipids relates to a less atherogenic lipoprotein profile in subjects with familial hypercholesterolemia. | 2013 | J. Nutr. Biochem. | pmid:23618530 |
| Shida T et al. | Colonic delivery of docosahexaenoic acid improves impaired glucose tolerance via GLP-1 secretion and suppresses pancreatic islet hyperplasia in diabetic KK-A(y) mice. | 2013 | Int J Pharm | pmid:23618969 |
| Johnston DT et al. | Red blood cell omega-3 fatty acid levels and neurocognitive performance in deployed U.S. Servicemembers. | 2013 | Nutr Neurosci | pmid:22748167 |
| Ravacci GR et al. | Lipid raft disruption by docosahexaenoic acid induces apoptosis in transformed human mammary luminal epithelial cells harboring HER-2 overexpression. | 2013 | J. Nutr. Biochem. | pmid:22749134 |
| Nicholson T et al. | The role of marine n-3 fatty acids in improving cardiovascular health: a review. | 2013 | Food Funct | pmid:23325431 |
| Hamaoka N et al. | Oxidative stability of lipids rich in EPA and DHA extracted from fermented scallop ovary. | 2013 | J. Food Sci. | pmid:23915081 |
| Jing K et al. | Omega-3 polyunsaturated fatty acids and cancer. | 2013 | Anticancer Agents Med Chem | pmid:23919748 |
| Santos VC et al. | Effects of DHA-rich fish oil supplementation on lymphocyte function before and after a marathon race. | 2013 | Int J Sport Nutr Exerc Metab | pmid:23239683 |
| O'Sullivan BP et al. | Evolution of pancreatic function during the first year in infants with cystic fibrosis. | 2013 | J. Pediatr. | pmid:23245194 |
| Harris WS et al. | Omega-3 fatty acids and cardiovascular disease: new developments and applications. | 2013 | Postgrad Med | pmid:24200766 |
| Fenton JI and McCaskey SJ | Curcumin and docosahexaenoic acid block insulin-induced colon carcinoma cell proliferation. | 2013 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:23266210 |
| Rogers LK et al. | DHA supplementation: current implications in pregnancy and childhood. | 2013 | Pharmacol. Res. | pmid:23266567 |
| Otsuka R et al. | Higher serum EPA or DHA, and lower ARA compositions with age independent fatty acid intake in Japanese aged 40 to 79. | 2013 | Lipids | pmid:23389403 |
| Andrade-Vieira R et al. | Omega-3 polyunsaturated fatty acid promotes the inhibition of glycolytic enzymes and mTOR signaling by regulating the tumor suppressor LKB1. | 2013 | Cancer Biol. Ther. | pmid:24025358 |
| Lachance C et al. | Fenretinide corrects the imbalance between omega-6 to omega-3 polyunsaturated fatty acids and inhibits macrophage inflammatory mediators via the ERK pathway. | 2013 | PLoS ONE | pmid:24069363 |
| Leggieri E et al. | Clinical effects of diet supplementation with DHA in pediatric patients suffering from cystic fibrosis. | 2013 | Minerva Pediatr. | pmid:24051972 |
| Cunnane SC et al. | Docosahexaenoic acid homeostasis, brain aging and Alzheimer's disease: Can we reconcile the evidence? | 2013 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:22575581 |
| Zou Z et al. | Inhibition of the HER2 pathway by n-3 polyunsaturated fatty acids prevents breast cancer in fat-1 transgenic mice. | 2013 | J. Lipid Res. | pmid:24052576 |
| Song X et al. | Different impacts of short-chain fatty acids on saturated and polyunsaturated fatty acid biosynthesis in Aurantiochytrium sp. SD116. | 2013 | J. Agric. Food Chem. | pmid:24053543 |
| Kenchegowda S et al. | Involvement of pigment epithelium-derived factor, docosahexaenoic acid and neuroprotectin D1 in corneal inflammation and nerve integrity after refractive surgery. | 2013 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:22579364 |