DHA
Dha is a lipid of Fatty Acyls (FA) class. Dha is associated with abnormalities such as Atherosclerosis, Consumption-archaic term for TB, Chronic disease, Cardiovascular Diseases and Diabetes Mellitus, Non-Insulin-Dependent. The involved functions are known as Inflammation, Oxidation, fatty acid oxidation, Fatty Acid Metabolism and Lipid Metabolism. Dha often locates in Hepatic, Protoplasm, Mucous Membrane, Epithelium and outer membrane. The associated genes with DHA are IMPACT gene, FATE1 gene, GAPDH gene, THOC4 gene and SLC33A1 gene. The related lipids are stearidonic acid, Fatty Acids, Total cholesterol, Lipopolysaccharides and Dietary Fatty Acid. The related experimental models are Mouse Model, Transgenic Model, Animal Disease Models and Arthritis, Experimental.
Cross Reference
Introduction
To understand associated biological information of DHA, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with DHA?
DHA is suspected in Cardiovascular Diseases, Obesity, Ischemia, Hypertensive disease, Coronary Arteriosclerosis, Cerebrovascular accident and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with DHA
PubChem Associated disorders and diseases
What pathways are associated with DHA
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with DHA?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with DHA?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with DHA?
Related references are published most in these journals:
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What genes are associated with DHA?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with DHA?
Mouse Model
Mouse Model are used in the study 'Homeostatic regulation of photoreceptor cell integrity: significance of the potent mediator neuroprotectin D1 biosynthesized from docosahexaenoic acid: the Proctor Lecture.' (Bazan NG, 2007), Mouse Model are used in the study 'Omega-3 fatty acids EPA and DHA: health benefits throughout life.' (Swanson D et al., 2012), Mouse Model are used in the study 'Docosahexaenoic acid attenuates hepatic inflammation, oxidative stress, and fibrosis without decreasing hepatosteatosis in a Ldlr(-/-) mouse model of western diet-induced nonalcoholic steatohepatitis.' (Depner CM et al., 2013) and Mouse Model are used in the study 'Wax esters from the marine copepod Calanus finmarchicus reduce diet-induced obesity and obesity-related metabolic disorders in mice.' (Höper AC et al., 2014).
Transgenic Model
Transgenic Model are used in the study 'Loss of MAP function leads to hippocampal synapse loss and deficits in the Morris Water Maze with aging.' (Ma QL et al., 2014).
Animal Disease Models
Animal Disease Models are used in the study 'Fish oil increases muscle protein mass and modulates Akt/FOXO, TLR4, and NOD signaling in weanling piglets after lipopolysaccharide challenge.' (Liu Y et al., 2013).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with DHA
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Hsiao HM et al. | Resolvin D1 Reduces Emphysema and Chronic Inflammation. | 2015 | Am. J. Pathol. | pmid:26468975 |
| Maekawa T et al. | Antagonistic effects of IL-17 and D-resolvins on endothelial Del-1 expression through a GSK-3β-C/EBPβ pathway. | 2015 | Nat Commun | pmid:26374165 |
| Herrera BS et al. | LXA4 actions direct fibroblast function and wound closure. | 2015 | Biochem. Biophys. Res. Commun. | pmid:26188508 |
| Guichardant M et al. | Omega-3 polyunsaturated fatty acids and oxygenated metabolism in atherothrombosis. | 2015 | Biochim. Biophys. Acta | pmid:25263947 |
| Gavzan H et al. | Synergistic effect of docosahexaenoic acid on anticonvulsant activity of valproic acid and lamotrigine in animal seizure models. | 2015 | Naunyn Schmiedebergs Arch. Pharmacol. | pmid:26018398 |
| Chiang N et al. | Identification of resolvin D2 receptor mediating resolution of infections and organ protection. | 2015 | J. Exp. Med. | pmid:26195725 |
| Wang X et al. | Resolution of inflammation is altered in Alzheimer's disease. | 2015 | Alzheimers Dement | pmid:24530025 |
| Orban T et al. | Serum levels of lipid metabolites in age-related macular degeneration. | 2015 | FASEB J. | pmid:26187344 |
| Wang CW et al. | Maresin 1 Biosynthesis and Proresolving Anti-infective Functions with Human-Localized Aggressive Periodontitis Leukocytes. | 2015 | Infect. Immun. | pmid:26667839 |
| Hashim RB et al. | Fatty acid compositions of silver catfish, Pangasius sp. farmed in several rivers of Pahang, Malaysia. | 2015 | J Oleo Sci | pmid:25748380 |
| Tyurina YY et al. | LC/MS analysis of cardiolipins in substantia nigra and plasma of rotenone-treated rats: Implication for mitochondrial dysfunction in Parkinson's disease. | 2015 | Free Radic. Res. | pmid:25740198 |
| Clouard C et al. | Dietary linoleic and α-linolenic acids affect anxiety-related responses and exploratory activity in growing pigs. | 2015 | J. Nutr. | pmid:25644359 |
| Sekhon-Loodu S et al. | Docosahexaenoic acid ester of phloridzin inhibit lipopolysaccharide-induced inflammation in THP-1 differentiated macrophages. | 2015 | Int. Immunopharmacol. | pmid:25637769 |
| Wang Y et al. | Mesoscopic simulation studies on the formation mechanism of drug loaded polymeric micelles. | 2015 | Colloids Surf B Biointerfaces | pmid:26454543 |
| Berge RK et al. | Krill oil reduces plasma triacylglycerol level and improves related lipoprotein particle concentration, fatty acid composition and redox status in healthy young adults - a pilot study. | 2015 | Lipids Health Dis | pmid:26666303 |
| Yoshinaga K et al. | Differential effects of triacylglycerol positional isomers containing n-3 series highly unsaturated fatty acids on lipid metabolism in C57BL/6J mice. | 2015 | J. Nutr. Biochem. | pmid:25448607 |
| Wang Y et al. | Maresin 1 Inhibits Epithelial-to-Mesenchymal Transition in Vitro and Attenuates Bleomycin Induced Lung Fibrosis in Vivo. | 2015 | Shock | pmid:26196843 |
| Block RC et al. | The effects of aspirin on platelet function and lysophosphatidic acids depend on plasma concentrations of EPA and DHA. | 2015 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:25555354 |
| Wijendran V et al. | Long-chain polyunsaturated fatty acids attenuate the IL-1β-induced proinflammatory response in human fetal intestinal epithelial cells. | 2015 | Pediatr. Res. | pmid:26270575 |
| Mansara PP et al. | Differential Ratios of Omega Fatty Acids (AA/EPA+DHA) Modulate Growth, Lipid Peroxidation and Expression of Tumor Regulatory MARBPs in Breast Cancer Cell Lines MCF7 and MDA-MB-231. | 2015 | PLoS ONE | pmid:26325577 |