| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hypothyroidism | D007037 | 32 associated lipids |
| Vision Disorders | D014786 | 10 associated lipids |
| Melanoma | D008545 | 69 associated lipids |
| Pain, Postoperative | D010149 | 13 associated lipids |
| Asthma | D001249 | 52 associated lipids |
| Kidney Diseases | D007674 | 29 associated lipids |
| Weight Gain | D015430 | 101 associated lipids |
| Hypersensitivity, Delayed | D006968 | 43 associated lipids |
| Glioma | D005910 | 112 associated lipids |
| Cell Transformation, Neoplastic | D002471 | 126 associated lipids |
| Hypercholesterolemia | D006937 | 91 associated lipids |
| Liver Neoplasms, Experimental | D008114 | 46 associated lipids |
| Bone Diseases, Metabolic | D001851 | 9 associated lipids |
| Obesity | D009765 | 29 associated lipids |
| Thrombosis | D013927 | 49 associated lipids |
| Uterine Neoplasms | D014594 | 18 associated lipids |
| Peritonitis | D010538 | 38 associated lipids |
| Proteinuria | D011507 | 30 associated lipids |
| Adrenoleukodystrophy | D000326 | 29 associated lipids |
| Refsum Disease | D012035 | 19 associated lipids |
DHA
Dha is a lipid of Fatty Acyls (FA) class. Dha is associated with abnormalities such as Atherosclerosis, Consumption-archaic term for TB, Chronic disease, Cardiovascular Diseases and Diabetes Mellitus, Non-Insulin-Dependent. The involved functions are known as Inflammation, Oxidation, fatty acid oxidation, Fatty Acid Metabolism and Lipid Metabolism. Dha often locates in Hepatic, Protoplasm, Mucous Membrane, Epithelium and outer membrane. The associated genes with DHA are IMPACT gene, FATE1 gene, GAPDH gene, THOC4 gene and SLC33A1 gene. The related lipids are stearidonic acid, Fatty Acids, Total cholesterol, Lipopolysaccharides and Dietary Fatty Acid. The related experimental models are Mouse Model, Transgenic Model, Animal Disease Models and Arthritis, Experimental.
Cross Reference
Introduction
To understand associated biological information of DHA, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with DHA?
DHA is suspected in Cardiovascular Diseases, Obesity, Ischemia, Hypertensive disease, Coronary Arteriosclerosis, Cerebrovascular accident and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with DHA
PubChem Associated disorders and diseases
What pathways are associated with DHA
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with DHA?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with DHA?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with DHA?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with DHA?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with DHA?
Mouse Model
Mouse Model are used in the study 'Homeostatic regulation of photoreceptor cell integrity: significance of the potent mediator neuroprotectin D1 biosynthesized from docosahexaenoic acid: the Proctor Lecture.' (Bazan NG, 2007), Mouse Model are used in the study 'Omega-3 fatty acids EPA and DHA: health benefits throughout life.' (Swanson D et al., 2012), Mouse Model are used in the study 'Docosahexaenoic acid attenuates hepatic inflammation, oxidative stress, and fibrosis without decreasing hepatosteatosis in a Ldlr(-/-) mouse model of western diet-induced nonalcoholic steatohepatitis.' (Depner CM et al., 2013) and Mouse Model are used in the study 'Wax esters from the marine copepod Calanus finmarchicus reduce diet-induced obesity and obesity-related metabolic disorders in mice.' (Höper AC et al., 2014).
Transgenic Model
Transgenic Model are used in the study 'Loss of MAP function leads to hippocampal synapse loss and deficits in the Morris Water Maze with aging.' (Ma QL et al., 2014).
Animal Disease Models
Animal Disease Models are used in the study 'Fish oil increases muscle protein mass and modulates Akt/FOXO, TLR4, and NOD signaling in weanling piglets after lipopolysaccharide challenge.' (Liu Y et al., 2013).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with DHA
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Véricel E et al. | Moderate oral supplementation with docosahexaenoic acid improves platelet function and oxidative stress in type 2 diabetic patients. | 2015 | Thromb. Haemost. | pmid:25832443 |
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| Picado C et al. | Effects of a fish oil enriched diet on aspirin intolerant asthmatic patients: a pilot study. | 1988 | Thorax | pmid:3353894 |
| Maldjian A et al. | Changes in sperm quality and lipid composition during cryopreservation of boar semen. | 2005 | Theriogenology | pmid:15626408 |
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| Cerolini S et al. | Effect of docosahexaenoic acid and alpha-tocopherol enrichment in chicken sperm on semen quality, sperm lipid composition and susceptibility to peroxidation. | 2006 | Theriogenology | pmid:16530814 |
| Brinsko SP et al. | Effect of feeding a DHA-enriched nutriceutical on the quality of fresh, cooled and frozen stallion semen. | 2005 | Theriogenology | pmid:15725455 |
| Gholami H et al. | Effect of feeding a docosahexaenoic acid-enriched nutriceutical on the quality of fresh and frozen-thawed semen in Holstein bulls. | 2010 | Theriogenology | pmid:20708237 |
| Gliozzi TM et al. | Quality and lipid composition of spermatozoa in rabbits fed DHA and vitamin E rich diets. | 2009 | Theriogenology | pmid:19121864 |
| Am-in N et al. | Lipid profiles of sperm and seminal plasma from boars having normal or low sperm motility. | 2011 | Theriogenology | pmid:21167582 |
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| Hsu K | Long-chain polyunsaturated fatty acids as anti-HIV supplementation during breastfeeding. | 2009 | Taiwan J Obstet Gynecol | pmid:19346195 |
| Young C et al. | Docosahexaenoic acid inhibits synaptic transmission and epileptiform activity in the rat hippocampus. | 2000 | Synapse | pmid:10881029 |
| Nakamura M et al. | Optimal dose of preoperative enteral immunonutrition for patients with esophageal cancer. | 2009 | Surg. Today | pmid:19784723 |
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| Green D et al. | A double-blind, placebo-controlled trial of fish oil concentrate (MaxEpa) in stroke patients. | 1985 Jul-Aug | Stroke | pmid:3895595 |
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| Imre SG et al. | Increased proportion of docosahexanoic acid and high lipid peroxidation capacity in erythrocytes of stroke patients. | 1994 | Stroke | pmid:7974583 |
| Nury T et al. | Induction of oxiapoptophagy on 158N murine oligodendrocytes treated by 7-ketocholesterol-, 7β-hydroxycholesterol-, or 24(S)-hydroxycholesterol: Protective effects of α-tocopherol and docosahexaenoic acid (DHA; C22:6 n-3). | 2015 | Steroids | pmid:25683890 |
| Ramaprasad TR et al. | Spray-dried milk supplemented with alpha-linolenic acid or eicosapentaenoic acid and docosahexaenoic acid decreases HMG Co A reductase activity and increases biliary secretion of lipids in rats. | 2006 | Steroids | pmid:16499938 |
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