DHA

Dha is a lipid of Fatty Acyls (FA) class. Dha is associated with abnormalities such as Atherosclerosis, Consumption-archaic term for TB, Chronic disease, Cardiovascular Diseases and Diabetes Mellitus, Non-Insulin-Dependent. The involved functions are known as Inflammation, Oxidation, fatty acid oxidation, Fatty Acid Metabolism and Lipid Metabolism. Dha often locates in Hepatic, Protoplasm, Mucous Membrane, Epithelium and outer membrane. The associated genes with DHA are IMPACT gene, FATE1 gene, GAPDH gene, THOC4 gene and SLC33A1 gene. The related lipids are stearidonic acid, Fatty Acids, Total cholesterol, Lipopolysaccharides and Dietary Fatty Acid. The related experimental models are Mouse Model, Transgenic Model, Animal Disease Models and Arthritis, Experimental.

Cross Reference

Introduction

To understand associated biological information of DHA, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with DHA?

DHA is suspected in Cardiovascular Diseases, Obesity, Ischemia, Hypertensive disease, Coronary Arteriosclerosis, Cerebrovascular accident and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with DHA

MeSH term MeSH ID Detail
Myocardial Reperfusion Injury D015428 20 associated lipids
Erythema D004890 22 associated lipids
Neoplasms, Hormone-Dependent D009376 23 associated lipids
Spinal Cord Injuries D013119 34 associated lipids
Ventricular Fibrillation D014693 16 associated lipids
Anaphylaxis D000707 35 associated lipids
Hyperlipidemias D006949 73 associated lipids
Pneumonia D011014 10 associated lipids
Coronary Artery Disease D003324 47 associated lipids
Encephalomyelitis, Autoimmune, Experimental D004681 26 associated lipids
Catalepsy D002375 30 associated lipids
Dermatitis, Atopic D003876 19 associated lipids
Vitamin E Deficiency D014811 29 associated lipids
Cardiomegaly D006332 31 associated lipids
Leiomyoma D007889 8 associated lipids
Niemann-Pick Diseases D009542 25 associated lipids
Peritoneal Neoplasms D010534 16 associated lipids
Nutrition Disorders D009748 6 associated lipids
Glomerulonephritis, IGA D005922 7 associated lipids
Pregnancy Complications, Cardiovascular D011249 11 associated lipids
Cardiomyopathy, Dilated D002311 15 associated lipids
Uveitis D014605 14 associated lipids
Biliary Atresia D001656 4 associated lipids
Cachexia D002100 21 associated lipids
Arthus Reaction D001183 8 associated lipids
Learning Disorders D007859 11 associated lipids
Retinitis Pigmentosa D012174 6 associated lipids
Angina Pectoris D000787 27 associated lipids
Angina, Unstable D000789 14 associated lipids
Vascular Diseases D014652 16 associated lipids
Pregnancy Complications, Hematologic D011250 11 associated lipids
Heart Defects, Congenital D006330 20 associated lipids
Listeriosis D008088 12 associated lipids
Anemia D000740 21 associated lipids
Infant, Premature, Diseases D007235 7 associated lipids
Hyperlipoproteinemias D006951 15 associated lipids
Fatty Liver, Alcoholic D005235 11 associated lipids
Keratitis D007634 7 associated lipids
Parkinson Disease D010300 53 associated lipids
Down Syndrome D004314 18 associated lipids
Carcinoma 256, Walker D002279 22 associated lipids
Central Nervous System Diseases D002493 10 associated lipids
Albinism D000417 3 associated lipids
Thymus Neoplasms D013953 15 associated lipids
Dysmenorrhea D004412 9 associated lipids
Myocarditis D009205 3 associated lipids
Influenza, Human D007251 11 associated lipids
Abortion, Habitual D000026 5 associated lipids
Basal Ganglia Diseases D001480 8 associated lipids
Dyskinesia, Drug-Induced D004409 15 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with DHA

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with DHA?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with DHA?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with DHA?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with DHA?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with DHA?

Mouse Model

Mouse Model are used in the study 'Homeostatic regulation of photoreceptor cell integrity: significance of the potent mediator neuroprotectin D1 biosynthesized from docosahexaenoic acid: the Proctor Lecture.' (Bazan NG, 2007), Mouse Model are used in the study 'Omega-3 fatty acids EPA and DHA: health benefits throughout life.' (Swanson D et al., 2012), Mouse Model are used in the study 'Docosahexaenoic acid attenuates hepatic inflammation, oxidative stress, and fibrosis without decreasing hepatosteatosis in a Ldlr(-/-) mouse model of western diet-induced nonalcoholic steatohepatitis.' (Depner CM et al., 2013) and Mouse Model are used in the study 'Wax esters from the marine copepod Calanus finmarchicus reduce diet-induced obesity and obesity-related metabolic disorders in mice.' (Höper AC et al., 2014).

Transgenic Model

Transgenic Model are used in the study 'Loss of MAP function leads to hippocampal synapse loss and deficits in the Morris Water Maze with aging.' (Ma QL et al., 2014).

Animal Disease Models

Animal Disease Models are used in the study 'Fish oil increases muscle protein mass and modulates Akt/FOXO, TLR4, and NOD signaling in weanling piglets after lipopolysaccharide challenge.' (Liu Y et al., 2013).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with DHA

Download all related citations
Per page 10 20 50 100 | Total 7336
Authors Title Published Journal PubMed Link
Das UN et al. Can tumour cell drug resistance be reversed by essential fatty acids and their metabolites? 1998 Prostaglandins Leukot. Essent. Fatty Acids pmid:9482165
Prasad MR et al. Regional membrane phospholipid alterations in Alzheimer's disease. 1998 Neurochem. Res. pmid:9482271
Nieuwenhuys CM and Hornstra G The effects of purified eicosapentaenoic and docosahexaenoic acids on arterial thrombosis tendency and platelet function in rats. 1998 Biochim. Biophys. Acta pmid:9487152
Ramesh G and Das UN Effect of cis-unsaturated fatty acids on Meth-A ascitic tumour cells in vitro and in vivo. 1998 Cancer Lett. pmid:9489490
Calviello G et al. Dietary supplementation with eicosapentaenoic and docosahexaenoic acid inhibits growth of Morris hepatocarcinoma 3924A in rats: effects on proliferation and apoptosis. 1998 Int. J. Cancer pmid:9495237
Alessandri JM et al. Docosahexaenoic acid concentrations in retinal phospholipids of piglets fed an infant formula enriched with long-chain polyunsaturated fatty acids: effects of egg phospholipids and fish oils with different ratios of eicosapentaenoic acid to docosahexaenoic acid. 1998 Am. J. Clin. Nutr. pmid:9497179
Hirafuji M et al. [Specific modulation of vascular smooth muscle cell functions by docosahexaenoic acid]. 1997 Nippon Yakurigaku Zasshi pmid:9503427
Woltil HA et al. Long-chain polyunsaturated fatty acid status and early growth of low birth weight infants. 1998 Eur. J. Pediatr. pmid:9504790
Morita N and Shirai J Effects of microcapsulated docosahexaenoic acid preparation on properties of dough and bread. 1997 J. Nutr. Sci. Vitaminol. pmid:9505244
Hansen JB et al. Effects of highly purified eicosapentaenoic acid and docosahexaenoic acid on fatty acid absorption, incorporation into serum phospholipids and postprandial triglyceridemia. 1998 Lipids pmid:9507234