DHA
Dha is a lipid of Fatty Acyls (FA) class. Dha is associated with abnormalities such as Atherosclerosis, Consumption-archaic term for TB, Chronic disease, Cardiovascular Diseases and Diabetes Mellitus, Non-Insulin-Dependent. The involved functions are known as Inflammation, Oxidation, fatty acid oxidation, Fatty Acid Metabolism and Lipid Metabolism. Dha often locates in Hepatic, Protoplasm, Mucous Membrane, Epithelium and outer membrane. The associated genes with DHA are IMPACT gene, FATE1 gene, GAPDH gene, THOC4 gene and SLC33A1 gene. The related lipids are stearidonic acid, Fatty Acids, Total cholesterol, Lipopolysaccharides and Dietary Fatty Acid. The related experimental models are Mouse Model, Transgenic Model, Animal Disease Models and Arthritis, Experimental.
Cross Reference
Introduction
To understand associated biological information of DHA, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with DHA?
DHA is suspected in Cardiovascular Diseases, Obesity, Ischemia, Hypertensive disease, Coronary Arteriosclerosis, Cerebrovascular accident and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with DHA
PubChem Associated disorders and diseases
What pathways are associated with DHA
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with DHA?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with DHA?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with DHA?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with DHA?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with DHA?
Mouse Model
Mouse Model are used in the study 'Homeostatic regulation of photoreceptor cell integrity: significance of the potent mediator neuroprotectin D1 biosynthesized from docosahexaenoic acid: the Proctor Lecture.' (Bazan NG, 2007), Mouse Model are used in the study 'Omega-3 fatty acids EPA and DHA: health benefits throughout life.' (Swanson D et al., 2012), Mouse Model are used in the study 'Docosahexaenoic acid attenuates hepatic inflammation, oxidative stress, and fibrosis without decreasing hepatosteatosis in a Ldlr(-/-) mouse model of western diet-induced nonalcoholic steatohepatitis.' (Depner CM et al., 2013) and Mouse Model are used in the study 'Wax esters from the marine copepod Calanus finmarchicus reduce diet-induced obesity and obesity-related metabolic disorders in mice.' (Höper AC et al., 2014).
Transgenic Model
Transgenic Model are used in the study 'Loss of MAP function leads to hippocampal synapse loss and deficits in the Morris Water Maze with aging.' (Ma QL et al., 2014).
Animal Disease Models
Animal Disease Models are used in the study 'Fish oil increases muscle protein mass and modulates Akt/FOXO, TLR4, and NOD signaling in weanling piglets after lipopolysaccharide challenge.' (Liu Y et al., 2013).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with DHA
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Liu YJ | [Biological activity and mechanism of action of eicosapentaenic acid and docosahexaenoic acid from fish oil]. | 1987 | Sheng Li Ke Xue Jin Zhan | pmid:2823380 |
| Goodnight SH | Effects of dietary fish oil and omega-3 fatty acids on platelets and blood vessels. | 1988 | Semin. Thromb. Hemost. | pmid:2845585 |
| McEwen BJ et al. | Effects of omega-3 polyunsaturated fatty acids on platelet function in healthy subjects and subjects with cardiovascular disease. | 2013 | Semin. Thromb. Hemost. | pmid:23329646 |
| Tam VC | Lipidomic profiling of bioactive lipids by mass spectrometry during microbial infections. | 2013 | Semin. Immunol. | pmid:24084369 |
| Carlson SE | Docosahexaenoic acid and arachidonic acid in infant development. | 2001 | Semin Neonatol | pmid:11988033 |
| Lee HN et al. | Resolution of inflammation as a novel chemopreventive strategy. | 2013 | Semin Immunopathol | pmid:23370700 |
| Ozawa H | [Omega-3 polyunsaturated fatty acids and mental disorders]. | 2009 | Seishin Shinkeigaku Zasshi | pmid:20344875 |
| Ozawa H | [Mood disorders and omega 3 polyunsaturated fatty acids]. | 2009 | Seishin Shinkeigaku Zasshi | pmid:20344877 |
| Nakagome K et al. | [Clinical application of omega 3 polyunsaturated fatty acids in psychiatry]. | 2009 | Seishin Shinkeigaku Zasshi | pmid:20344878 |
| Hamazaki T et al. | [Emotion and omega 3 polyunsaturated fatty acids]. | 2009 | Seishin Shinkeigaku Zasshi | pmid:20344879 |
| Matsuoka Y and Nishi D | [Possible use of omega 3 polyunsaturated fatty acids for prevention of PTSD]. | 2009 | Seishin Shinkeigaku Zasshi | pmid:20344880 |
| Yoshikawa T | [Schizophrenia and omega 3 polyunsaturated fatty acids]. | 2009 | Seishin Shinkeigaku Zasshi | pmid:20344881 |
| Yui K et al. | [Effects of arachidonic acids on social behavior in patients with autism spectrum disorders]. | 2009 | Seishin Shinkeigaku Zasshi | pmid:20217968 |
| Arita M and Isobe Y | [Structure and function of anti-inflammatory lipid mediators derived from omega-3 polyunsaturated fatty acids]. | 2008 | Seikagaku | pmid:19086412 |
| Masuzawa Y | [The mysteries of docosahexaenoic acid--possible functions of C22 polyenoic fatty acids]. | 1988 | Seikagaku | pmid:2976795 |
| Zhang Q and Ma Y | [Determination of EPA and DHA in marine microalgaes by GC]. | 2004 | Se Pu | pmid:15807130 |
| Lu J et al. | [Analysis of fatty acids in tissues of Penaeus vannamei cultured in sea- and fresh-waters by ultrasonic extraction-capillary gas chromatography]. | 2005 | Se Pu | pmid:16013568 |
| Seki H et al. | Resolvins as regulators of the immune system. | 2010 | ScientificWorldJournal | pmid:20454764 |
| Börgeson E and Godson C | Molecular circuits of resolution in renal disease. | 2010 | ScientificWorldJournal | pmid:20623097 |
| Morris T et al. | New perspectives on aspirin and the endogenous control of acute inflammatory resolution. | 2006 | ScientificWorldJournal | pmid:16951898 |