DHA
Dha is a lipid of Fatty Acyls (FA) class. Dha is associated with abnormalities such as Atherosclerosis, Consumption-archaic term for TB, Chronic disease, Cardiovascular Diseases and Diabetes Mellitus, Non-Insulin-Dependent. The involved functions are known as Inflammation, Oxidation, fatty acid oxidation, Fatty Acid Metabolism and Lipid Metabolism. Dha often locates in Hepatic, Protoplasm, Mucous Membrane, Epithelium and outer membrane. The associated genes with DHA are IMPACT gene, FATE1 gene, GAPDH gene, THOC4 gene and SLC33A1 gene. The related lipids are stearidonic acid, Fatty Acids, Total cholesterol, Lipopolysaccharides and Dietary Fatty Acid. The related experimental models are Mouse Model, Transgenic Model, Animal Disease Models and Arthritis, Experimental.
Cross Reference
Introduction
To understand associated biological information of DHA, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with DHA?
DHA is suspected in Cardiovascular Diseases, Obesity, Ischemia, Hypertensive disease, Coronary Arteriosclerosis, Cerebrovascular accident and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with DHA
PubChem Associated disorders and diseases
What pathways are associated with DHA
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with DHA?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with DHA?
Related references are published most in these journals:
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What lipids are associated with DHA?
Related references are published most in these journals:
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What genes are associated with DHA?
Related references are published most in these journals:
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What common seen animal models are associated with DHA?
Mouse Model
Mouse Model are used in the study 'Homeostatic regulation of photoreceptor cell integrity: significance of the potent mediator neuroprotectin D1 biosynthesized from docosahexaenoic acid: the Proctor Lecture.' (Bazan NG, 2007), Mouse Model are used in the study 'Omega-3 fatty acids EPA and DHA: health benefits throughout life.' (Swanson D et al., 2012), Mouse Model are used in the study 'Docosahexaenoic acid attenuates hepatic inflammation, oxidative stress, and fibrosis without decreasing hepatosteatosis in a Ldlr(-/-) mouse model of western diet-induced nonalcoholic steatohepatitis.' (Depner CM et al., 2013) and Mouse Model are used in the study 'Wax esters from the marine copepod Calanus finmarchicus reduce diet-induced obesity and obesity-related metabolic disorders in mice.' (Höper AC et al., 2014).
Transgenic Model
Transgenic Model are used in the study 'Loss of MAP function leads to hippocampal synapse loss and deficits in the Morris Water Maze with aging.' (Ma QL et al., 2014).
Animal Disease Models
Animal Disease Models are used in the study 'Fish oil increases muscle protein mass and modulates Akt/FOXO, TLR4, and NOD signaling in weanling piglets after lipopolysaccharide challenge.' (Liu Y et al., 2013).
Related references are published most in these journals:
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NCBI Entrez Crosslinks
All references with DHA
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Werkman SH and Carlson SE | A randomized trial of visual attention of preterm infants fed docosahexaenoic acid until nine months. | 1996 | Lipids | pmid:8649241 |
| Jørgensen MH et al. | Visual acuity and erythrocyte docosahexaenoic acid status in breast-fed and formula-fed term infants during the first four months of life. | 1996 | Lipids | pmid:8649242 |
| Balestrieri GP et al. | Fish oil supplementation in patients with heterozygous familial hypercholesterolemia. | 1996 | Recenti Prog Med | pmid:8650428 |
| Beijers RJ and Schaafsma A | Long-chain polyunsaturated fatty acid content in Dutch preterm breast milk; differences in the concentrations of docosahexaenoic acid and arachidonic acid due to length of gestation. | 1996 | Early Hum. Dev. | pmid:8654314 |
| Moore SA et al. | Docosahexaenoic acid synthesis in human skin fibroblasts involves peroxisomal retroconversion of tetracosahexaenoic acid. | 1995 | J. Lipid Res. | pmid:8656081 |
| Luthria DL et al. | Regulation of the biosynthesis of 4,7,10,13,16,19-docosahexaenoic acid. | 1996 | J. Biol. Chem. | pmid:8663162 |
| Marzo I et al. | Biosynthesis of docosahexaenoic acid in human cells: evidence that two different delta 6-desaturase activities may exist. | 1996 | Biochim. Biophys. Acta | pmid:8664338 |
| Innis SM et al. | Feeding formula without arachidonic acid and docosahexaenoic acid has no effect on preferential looking acuity or recognition memory in healthy full-term infants at 9 mo of age. | 1996 | Am. J. Clin. Nutr. | pmid:8669412 |
| Rotstein NP et al. | Active synthesis of C24:5, n-3 fatty acid in retina. | 1996 | Biochem. J. | pmid:8670163 |
| Lagarde M | [Biosynthesis and functions of eicosanoids. Recent data]. | 1995 | C. R. Seances Soc. Biol. Fil. | pmid:8673630 |
| Tamura M and Suzuki H | Effect of docosahexaenoic acid and sardine oil diets on the ultrastructure of hepatocytes in adult mice. | 1995 | J. Nutr. Sci. Vitaminol. | pmid:8676220 |
| Yamane M et al. | Subcellular localization of docosahexaenoic acid and arachidonic acid omega-hydroxylation activity in the brain, liver and colonic adenocarcinoma. | 1996 | J Chromatogr A | pmid:8680600 |
| Innis SM and Hansen JW | Plasma fatty acid responses, metabolic effects, and safety of microalgal and fungal oils rich in arachidonic and docosahexaenoic acids in healthy adults. | 1996 | Am. J. Clin. Nutr. | pmid:8694015 |
| Lim BO et al. | Effects of n-3 polyunsaturated fatty acids and lectins on immunoglobulin production by spleen lymphocytes of Sprague-Dawley rats. | 1996 | Biosci. Biotechnol. Biochem. | pmid:8695902 |
| Chen Y et al. | Docosahexaenoic acid modulates the interactions of the interphotoreceptor retinoid-binding protein with 11-cis-retinal. | 1996 | J. Biol. Chem. | pmid:8702792 |
| Hammes HP et al. | Acceleration of experimental diabetic retinopathy in the rat by omega-3 fatty acids. | 1996 | Diabetologia | pmid:8721768 |
| Carlson SE et al. | Visual acuity and fatty acid status of term infants fed human milk and formulas with and without docosahexaenoate and arachidonate from egg yolk lecithin. | 1996 | Pediatr. Res. | pmid:8726246 |
| De Caterina R and Libby P | Control of endothelial leukocyte adhesion molecules by fatty acids. | 1996 | Lipids | pmid:8729095 |
| Croset M et al. | In vivo compartmental metabolism of 13C-docosahexaenoic acid, studied by gas chromatography-combustion isotope ratio mass spectrometry. | 1996 | Lipids | pmid:8729104 |
| Martinez M | Docosahexaenoic acid therapy in docosahexaenoic acid-deficient patients with disorders of peroxisomal biogenesis. | 1996 | Lipids | pmid:8729110 |
| Gibson RA et al. | Effect of dietary docosahexaenoic acid on brain composition and neural function in term infants. | 1996 | Lipids | pmid:8729115 |
| Connor WE et al. | Increased docosahexaenoic acid levels in human newborn infants by administration of sardines and fish oil during pregnancy. | 1996 | Lipids | pmid:8729116 |
| Green P and Yavin E | Natural and accelerated docosahexaenoic acid accumulation in the prenatal rat brain. | 1996 | Lipids | pmid:8729125 |
| Cerolini S et al. | Preferential mobilisation of docosahexaenoic acid from adipose tissue triacylglycerol of the chick embryo. | 1996 | Biochem. Soc. Trans. | pmid:8736823 |
| Boehm G et al. | Docosahexaenoic and arachidonic acid content of serum and red blood cell membrane phospholipids of preterm infants fed breast milk, standard formula or formula supplemented with n-3 and n-6 long-chain polyunsaturated fatty acids. | 1996 | Eur. J. Pediatr. | pmid:8741041 |
| McLennan P et al. | The cardiovascular protective role of docosahexaenoic acid. | 1996 | Eur. J. Pharmacol. | pmid:8741170 |
| Sasaki H et al. | [Immunosuppressive effect of intravenously injected docosahexaenoic acid on single lung allotransplantation in the rat]. | 1996 | Nihon Kyobu Geka Gakkai Zasshi | pmid:8741552 |
| Degrace P et al. | Intestinal lymph absorption of butter, corn oil, cod liver oil, menhaden oil, and eicosapentaenoic and docosahexaenoic acid ethyl esters in rats. | 1996 | Lipids | pmid:8743053 |
| Yamada Y et al. | Effect of eicosapentaenoic acid and docosahexaenoic acid on diabetic osteopenia. | 1995 | Diabetes Res. Clin. Pract. | pmid:8745204 |
| Boswell K et al. | Preclinical evaluation of single-cell oils that are highly enriched with arachidonic acid and docosahexaenoic acid. | 1996 | Food Chem. Toxicol. | pmid:8761351 |
| Weisinger HS et al. | Effect of dietary n-3 deficiency on the electroretinogram in the guinea pig. | 1996 | Ann. Nutr. Metab. | pmid:8773733 |
| Maccoll AJ et al. | Erythrocyte morphology and filterability in rats fed on diets containing different fats and oils. | 1996 | Br. J. Nutr. | pmid:8774223 |
| Rotstein NP et al. | Docosahexaenoic acid is required for the survival of rat retinal photoreceptors in vitro. | 1996 | J. Neurochem. | pmid:8780010 |
| Lecomte M et al. | Docosahexaenoic acid is a major n-3 polyunsaturated fatty acid in bovine retinal microvessels. | 1996 | J. Neurochem. | pmid:8780049 |
| Palozza P et al. | n-3 fatty acids induce oxidative modifications in human erythrocytes depending on dose and duration of dietary supplementation. | 1996 | Am. J. Clin. Nutr. | pmid:8780337 |
| Minami M and Noguchi M | Effects of low-dose eicosapentaenoic acid, docosahexaenoic acid and dietary fat on the incidence, growth and cell kinetics of mammary carcinomas in rats. | 1996 Sep-Oct | Oncology | pmid:8784475 |
| Willumsen N et al. | Eicosapentaenoic acid, but not docosahexaenoic acid, increases mitochondrial fatty acid oxidation and upregulates 2,4-dienoyl-CoA reductase gene expression in rats. | 1996 | Lipids | pmid:8784738 |
| Innis SM et al. | Blood lipid docosahexaenoic and arachidonic acid in term gestation infants fed formulas with high docosahexaenoic acid, low eicosapentaenoic acid fish oil. | 1996 | Lipids | pmid:8784742 |
| Dembitsky VM and Rezanka T | Unusually high levels of eicosatetraenoic, eicosapentaenoic, and docosahexaenoic fatty acids in Palestinian freshwater sponges. | 1996 | Lipids | pmid:8784746 |
| Mitjavila MT et al. | Effect of degree of unsaturation in dietary fatty acids on arachidonic acid mobilization by peritoneal macrophages. | 1996 | Lipids | pmid:8784749 |
| Simonelli F et al. | Evaluation of fatty acids in membrane phospholipids of erythrocytes in retinitis pigmentosa patients. | 1996 | Ophthalmic Res. | pmid:8792359 |
| Carnielli VP et al. | The very low birth weight premature infant is capable of synthesizing arachidonic and docosahexaenoic acids from linoleic and linolenic acids. | 1996 | Pediatr. Res. | pmid:8798265 |
| Xu LZ et al. | Ligand specificity of brain lipid-binding protein. | 1996 | J. Biol. Chem. | pmid:8798739 |
| Fernández-Bañares F et al. | Changes of the mucosal n3 and n6 fatty acid status occur early in the colorectal adenoma-carcinoma sequence. | 1996 | Gut | pmid:8801207 |
| Huang MC and Craig-Schmidt MC | Arachidonate and docosahexaenoate added to infant formula influence fatty acid composition and subsequent eicosanoid production in neonatal pigs. | 1996 | J. Nutr. | pmid:8814208 |
| Pöschl JM et al. | Dietary docosahexaenoic acid improves red blood cell deformability in rats. | 1996 | Thromb. Res. | pmid:8822144 |
| Bayorh MA et al. | Effects of MaxEPA on salt-induced hypertension: relationship to [3H]nitrobenzylthioinosine binding sites. | 1996 | Clin. Exp. Hypertens. | pmid:8822232 |
| Polette A et al. | N-3 fatty acid-induced lipid peroxidation in human platelets is prevented by catechins. | 1996 | Thromb. Haemost. | pmid:8822591 |
| Ku K et al. | The effects of omega-3 polyunsaturated (correction of polyunsatulated) fatty acids on the recovery of cardiac function following cold preservation and reperfusion in hyperlipidemic rats. | 1996 | Transplantation | pmid:8824469 |
| Khair-el-Din TA et al. | Inhibition of macrophage nitric-oxide production and Ia-expression by docosahexaenoic acid, a constituent of fetal and neonatal serum. | 1996 | Am. J. Reprod. Immunol. | pmid:8831896 |