DHA

Dha is a lipid of Fatty Acyls (FA) class. Dha is associated with abnormalities such as Atherosclerosis, Consumption-archaic term for TB, Chronic disease, Cardiovascular Diseases and Diabetes Mellitus, Non-Insulin-Dependent. The involved functions are known as Inflammation, Oxidation, fatty acid oxidation, Fatty Acid Metabolism and Lipid Metabolism. Dha often locates in Hepatic, Protoplasm, Mucous Membrane, Epithelium and outer membrane. The associated genes with DHA are IMPACT gene, FATE1 gene, GAPDH gene, THOC4 gene and SLC33A1 gene. The related lipids are stearidonic acid, Fatty Acids, Total cholesterol, Lipopolysaccharides and Dietary Fatty Acid. The related experimental models are Mouse Model, Transgenic Model, Animal Disease Models and Arthritis, Experimental.

Cross Reference

Introduction

To understand associated biological information of DHA, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with DHA?

DHA is suspected in Cardiovascular Diseases, Obesity, Ischemia, Hypertensive disease, Coronary Arteriosclerosis, Cerebrovascular accident and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with DHA

MeSH term MeSH ID Detail
Retinal Detachment D012163 10 associated lipids
Carcinoma, Lewis Lung D018827 22 associated lipids
Choline Deficiency D002796 16 associated lipids
Medulloblastoma D008527 22 associated lipids
Zellweger Syndrome D015211 39 associated lipids
Atrial Fibrillation D001281 16 associated lipids
Coronary Thrombosis D003328 7 associated lipids
Ventricular Dysfunction, Left D018487 33 associated lipids
Aortic Diseases D001018 11 associated lipids
Genetic Predisposition to Disease D020022 24 associated lipids
Hepatitis C D006526 7 associated lipids
Atherosclerosis D050197 85 associated lipids
Leukemia-Lymphoma, Adult T-Cell D015459 25 associated lipids
Multiple Sclerosis, Relapsing-Remitting D020529 7 associated lipids
Metabolic Syndrome D024821 44 associated lipids
Dyslexia D004410 3 associated lipids
Hypercalciuria D053565 4 associated lipids
Diabetes, Gestational D016640 8 associated lipids
Acute Coronary Syndrome D054058 11 associated lipids
Plaque, Atherosclerotic D058226 7 associated lipids
Malnutrition D044342 6 associated lipids
Insulin Resistance D007333 99 associated lipids
Diabetes Complications D048909 4 associated lipids
Sleep Apnea, Obstructive D020181 9 associated lipids
Peripheral Arterial Disease D058729 7 associated lipids
Intracranial Arteriosclerosis D002537 4 associated lipids
Macular Degeneration D008268 5 associated lipids
Dyslipidemias D050171 7 associated lipids
Asthma, Exercise-Induced D001250 10 associated lipids
Deficiency Diseases D003677 12 associated lipids
Pregnancy Complications D011248 19 associated lipids
Myoglobinuria D009212 3 associated lipids
Weight Loss D015431 56 associated lipids
Critical Illness D016638 13 associated lipids
Blister D001768 16 associated lipids
Memory Disorders D008569 33 associated lipids
Glucose Intolerance D018149 13 associated lipids
Parkinson Disease, Secondary D010302 17 associated lipids
Dry Eye Syndromes D015352 10 associated lipids
Acute Lung Injury D055371 33 associated lipids
Death, Sudden, Cardiac D016757 12 associated lipids
Neurodegenerative Diseases D019636 32 associated lipids
Lupus Nephritis D008181 8 associated lipids
Parkinsonian Disorders D020734 20 associated lipids
Neuralgia D009437 28 associated lipids
Peripheral Nerve Injuries D059348 6 associated lipids
Muscular Dystrophy, Duchenne D020388 11 associated lipids
Keratitis, Herpetic D016849 5 associated lipids
Sleep Wake Disorders D012893 7 associated lipids
Burkholderia Infections D019121 7 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with DHA

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with DHA?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with DHA?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with DHA?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with DHA?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with DHA?

Mouse Model

Mouse Model are used in the study 'Homeostatic regulation of photoreceptor cell integrity: significance of the potent mediator neuroprotectin D1 biosynthesized from docosahexaenoic acid: the Proctor Lecture.' (Bazan NG, 2007), Mouse Model are used in the study 'Omega-3 fatty acids EPA and DHA: health benefits throughout life.' (Swanson D et al., 2012), Mouse Model are used in the study 'Docosahexaenoic acid attenuates hepatic inflammation, oxidative stress, and fibrosis without decreasing hepatosteatosis in a Ldlr(-/-) mouse model of western diet-induced nonalcoholic steatohepatitis.' (Depner CM et al., 2013) and Mouse Model are used in the study 'Wax esters from the marine copepod Calanus finmarchicus reduce diet-induced obesity and obesity-related metabolic disorders in mice.' (Höper AC et al., 2014).

Transgenic Model

Transgenic Model are used in the study 'Loss of MAP function leads to hippocampal synapse loss and deficits in the Morris Water Maze with aging.' (Ma QL et al., 2014).

Animal Disease Models

Animal Disease Models are used in the study 'Fish oil increases muscle protein mass and modulates Akt/FOXO, TLR4, and NOD signaling in weanling piglets after lipopolysaccharide challenge.' (Liu Y et al., 2013).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with DHA

Download all related citations
Per page 10 20 50 100 | Total 7336
Authors Title Published Journal PubMed Link
Das UN et al. Can tumour cell drug resistance be reversed by essential fatty acids and their metabolites? 1998 Prostaglandins Leukot. Essent. Fatty Acids pmid:9482165
Prasad MR et al. Regional membrane phospholipid alterations in Alzheimer's disease. 1998 Neurochem. Res. pmid:9482271
Nieuwenhuys CM and Hornstra G The effects of purified eicosapentaenoic and docosahexaenoic acids on arterial thrombosis tendency and platelet function in rats. 1998 Biochim. Biophys. Acta pmid:9487152
Ramesh G and Das UN Effect of cis-unsaturated fatty acids on Meth-A ascitic tumour cells in vitro and in vivo. 1998 Cancer Lett. pmid:9489490
Calviello G et al. Dietary supplementation with eicosapentaenoic and docosahexaenoic acid inhibits growth of Morris hepatocarcinoma 3924A in rats: effects on proliferation and apoptosis. 1998 Int. J. Cancer pmid:9495237
Alessandri JM et al. Docosahexaenoic acid concentrations in retinal phospholipids of piglets fed an infant formula enriched with long-chain polyunsaturated fatty acids: effects of egg phospholipids and fish oils with different ratios of eicosapentaenoic acid to docosahexaenoic acid. 1998 Am. J. Clin. Nutr. pmid:9497179
Hirafuji M et al. [Specific modulation of vascular smooth muscle cell functions by docosahexaenoic acid]. 1997 Nippon Yakurigaku Zasshi pmid:9503427
Woltil HA et al. Long-chain polyunsaturated fatty acid status and early growth of low birth weight infants. 1998 Eur. J. Pediatr. pmid:9504790
Morita N and Shirai J Effects of microcapsulated docosahexaenoic acid preparation on properties of dough and bread. 1997 J. Nutr. Sci. Vitaminol. pmid:9505244
Hansen JB et al. Effects of highly purified eicosapentaenoic acid and docosahexaenoic acid on fatty acid absorption, incorporation into serum phospholipids and postprandial triglyceridemia. 1998 Lipids pmid:9507234