| MeSH term | MeSH ID | Detail |
|---|---|---|
| Precancerous Conditions | D011230 | 48 associated lipids |
| Carcinoma | D002277 | 18 associated lipids |
| Hypotension | D007022 | 41 associated lipids |
| Acute Kidney Injury | D058186 | 34 associated lipids |
| Dementia | D003704 | 2 associated lipids |
| Heart Failure | D006333 | 36 associated lipids |
| Coronary Disease | D003327 | 70 associated lipids |
| Prostatic Neoplasms | D011471 | 126 associated lipids |
| Hypersensitivity | D006967 | 22 associated lipids |
| Brain Neoplasms | D001932 | 15 associated lipids |
DHA
Dha is a lipid of Fatty Acyls (FA) class. Dha is associated with abnormalities such as Atherosclerosis, Consumption-archaic term for TB, Chronic disease, Cardiovascular Diseases and Diabetes Mellitus, Non-Insulin-Dependent. The involved functions are known as Inflammation, Oxidation, fatty acid oxidation, Fatty Acid Metabolism and Lipid Metabolism. Dha often locates in Hepatic, Protoplasm, Mucous Membrane, Epithelium and outer membrane. The associated genes with DHA are IMPACT gene, FATE1 gene, GAPDH gene, THOC4 gene and SLC33A1 gene. The related lipids are stearidonic acid, Fatty Acids, Total cholesterol, Lipopolysaccharides and Dietary Fatty Acid. The related experimental models are Mouse Model, Transgenic Model, Animal Disease Models and Arthritis, Experimental.
Cross Reference
Introduction
To understand associated biological information of DHA, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with DHA?
DHA is suspected in Cardiovascular Diseases, Obesity, Ischemia, Hypertensive disease, Coronary Arteriosclerosis, Cerebrovascular accident and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with DHA
PubChem Associated disorders and diseases
What pathways are associated with DHA
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with DHA?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with DHA?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with DHA?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with DHA?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with DHA?
Mouse Model
Mouse Model are used in the study 'Homeostatic regulation of photoreceptor cell integrity: significance of the potent mediator neuroprotectin D1 biosynthesized from docosahexaenoic acid: the Proctor Lecture.' (Bazan NG, 2007), Mouse Model are used in the study 'Omega-3 fatty acids EPA and DHA: health benefits throughout life.' (Swanson D et al., 2012), Mouse Model are used in the study 'Docosahexaenoic acid attenuates hepatic inflammation, oxidative stress, and fibrosis without decreasing hepatosteatosis in a Ldlr(-/-) mouse model of western diet-induced nonalcoholic steatohepatitis.' (Depner CM et al., 2013) and Mouse Model are used in the study 'Wax esters from the marine copepod Calanus finmarchicus reduce diet-induced obesity and obesity-related metabolic disorders in mice.' (Höper AC et al., 2014).
Transgenic Model
Transgenic Model are used in the study 'Loss of MAP function leads to hippocampal synapse loss and deficits in the Morris Water Maze with aging.' (Ma QL et al., 2014).
Animal Disease Models
Animal Disease Models are used in the study 'Fish oil increases muscle protein mass and modulates Akt/FOXO, TLR4, and NOD signaling in weanling piglets after lipopolysaccharide challenge.' (Liu Y et al., 2013).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with DHA
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| pmid:28316988 | ||||
| Karmali RA et al. | The effects of dietary omega-3 fatty acids on the DU-145 transplantable human prostatic tumor. | 1987 Nov-Dec | Anticancer Res. | pmid:2831791 |
| pmid:28319894 | ||||
| Covens AL et al. | The effect of dietary supplementation with fish oil fatty acids on surgically induced endometriosis in the rabbit. | 1988 | Fertil. Steril. | pmid:2832216 |
| pmid:28322829 | ||||
| pmid:28324081 | ||||
| pmid:28330470 | ||||
| pmid:28330907 | ||||
| pmid:28330911 | ||||
| Ackman RG | Some possible effects on lipid biochemistry of differences in the distribution on glycerol of long-chain n-3 fatty acids in the fats of marine fish and marine mammals. | 1988 | Atherosclerosis | pmid:2833284 |
| pmid:28333036 | ||||
| pmid:28335478 | ||||
| pmid:28335828 | ||||
| pmid:28338369 | ||||
| pmid:28341437 | ||||
| pmid:28342541 | ||||
| pmid:28342772 | ||||
| pmid:28342842 | ||||
| pmid:28343553 | ||||
| pmid:28346830 | ||||
| Blachier F et al. | Arachidonic acid metabolism and casein secretion in lactating rabbit mammary epithelial cells: effects of inhibitors of prostaglandins and leukotrienes synthesis. | 1988 | Prostaglandins | pmid:2834771 |
| pmid:28347768 | ||||
| pmid:28347928 | ||||
| pmid:28355511 | ||||
| pmid:28356106 | ||||
| pmid:28359716 | ||||
| Nielsen M et al. | [3H]diazepam specific binding to rat cortex in vitro is enhanced by oleic, arachidonic and docosahexenoic acid isolated from pig brain. | 1988 | Eur. J. Pharmacol. | pmid:2836212 |
| Mottola G et al. | Aspirin-triggered resolvin D1 attenuates PDGF-induced vascular smooth muscle cell migration via the cyclic adenosine monophosphate/protein kinase A (cAMP/PKA) pathway. | 2017 | PLoS ONE | pmid:28362840 |
| pmid:28364876 | ||||
| pmid:28365353 | ||||
| Garg ML et al. | Effect of dietary cholesterol and/or omega 3 fatty acids on lipid composition and delta 5-desaturase activity of rat liver microsomes. | 1988 | J. Nutr. | pmid:2836574 |
| Burak C et al. | Effects of the flavonol quercetin and α-linolenic acid on n-3 PUFA status in metabolically healthy men and women: a randomised, double-blinded, placebo-controlled, crossover trial. | 2017 | Br. J. Nutr. | pmid:28366181 |
| pmid:28369884 | ||||
| pmid:28372209 | ||||
| pmid:28373143 | ||||
| pmid:28379169 | ||||
| pmid:28379964 | ||||
| pmid:28385289 | ||||
| pmid:28388313 | ||||
| Croset M et al. | Different metabolic behavior of long-chain n-3 polyunsaturated fatty acids in human platelets. | 1988 | Biochim. Biophys. Acta | pmid:2839237 |
| pmid:28394002 | ||||
| pmid:28400162 | ||||
| pmid:28403232 | ||||
| pmid:28404641 | ||||
| Hörcher U | [Omega-3-fatty acids from fish oil for the prevention of myocardial infarct]. | 1988 | Pharm Unserer Zeit | pmid:2840674 |
| Debbabi M et al. | Comparison of the effects of major fatty acids present in the Mediterranean diet (oleic acid, docosahexaenoic acid) and in hydrogenated oils (elaidic acid) on 7-ketocholesterol-induced oxiapoptophagy in microglial BV-2 cells. | 2017 | Chem. Phys. Lipids | pmid:28408132 |
| pmid:28409336 | ||||
| Souza CO et al. | Milk protein-based formulas containing different oils affect fatty acids balance in term infants: A randomized blinded crossover clinical trial. | 2017 | Lipids Health Dis | pmid:28410612 |
| pmid:28410617 | ||||
| pmid:28410665 | ||||
| pmid:28410667 | ||||
| pmid:28410668 | ||||
| pmid:28410669 | ||||
| Ishiguro J et al. | [Effects of ethyl eicosapentaenoate (EPA-E) and its metabolite on the drug and fatty acid metabolizing enzyme systems in rat liver]. | 1988 | Yakugaku Zasshi | pmid:2841446 |
| Cardiovascular effects of n-3 fatty acids. | 1988 | N. Engl. J. Med. | pmid:2841599 | |
| Palmblad J and Gyllenhammar H | Effect of dietary lipids on immunity and inflammation. Review article. | 1988 | APMIS | pmid:2841953 |
| pmid:28422962 | ||||
| pmid:28424185 | ||||
| pmid:28430183 | ||||
| pmid:28430821 | ||||
| pmid:28433363 | ||||
| pmid:28433582 | ||||
| pmid:28438023 | ||||
| pmid:28441337 | ||||
| pmid:28442547 | ||||
| Garg ML et al. | Fish oil reduces cholesterol and arachidonic acid content more efficiently in rats fed diets containing low linoleic acid to saturated fatty acid ratios. | 1988 | Biochim. Biophys. Acta | pmid:2844278 |
| pmid:28443847 | ||||
| pmid:28446501 | ||||
| Goodnight SH | Effects of dietary fish oil and omega-3 fatty acids on platelets and blood vessels. | 1988 | Semin. Thromb. Hemost. | pmid:2845585 |
| pmid:28456627 | ||||
| pmid:28457318 | ||||
| pmid:28462988 | ||||
| pmid:28463780 | ||||
| pmid:28465065 | ||||
| pmid:28465323 | ||||
| pmid:28465656 | ||||
| pmid:28468627 | ||||
| Lawson LD and Hughes BG | Absorption of eicosapentaenoic acid and docosahexaenoic acid from fish oil triacylglycerols or fish oil ethyl esters co-ingested with a high-fat meal. | 1988 | Biochem. Biophys. Res. Commun. | pmid:2847723 |
| pmid:28481011 | ||||
| Wong SH and Marsh JB | Inhibition of apolipoprotein secretion and phosphatidate phosphohydrolase activity by eicosapentaenoic and docosahexaenoic acids in the perfused rat liver. | 1988 | Metab. Clin. Exp. | pmid:2848178 |
| pmid:28483666 | ||||
| pmid:28495174 | ||||
| pmid:28500069 | ||||
| pmid:28502496 | ||||
| pmid:28511049 | ||||
| Shimokawa H et al. | Dietary omega 3 polyunsaturated fatty acids augment endothelium-dependent relaxation to bradykinin in coronary microvessels of the pig. | 1988 | Br. J. Pharmacol. | pmid:2851360 |
| pmid:28515020 | ||||
| pmid:28515069 | ||||
| pmid:28515269 | ||||
| Maoka T et al. | Carotenoids of Red, Brown, and Black Specimens of Plectropomus leopardus, the Coral Trout (Suziara in Japanese). | 2017 | J Oleo Sci | pmid:28515376 |
| Huang WH et al. | Control of the sodium pump by liponucleotides and unsaturated fatty acids: side-dependent effects in red cells. | 1988 | Prog. Clin. Biol. Res. | pmid:2851818 |
| Kremer JM | Omega-3 fatty acids in rheumatoid arthritis. | 1988 | Del Med J | pmid:2852607 |
| Wang Y et al. | Docosahexaenoyl serotonin emerges as most potent inhibitor of IL-17 and CCL-20 released by blood mononuclear cells from a series of N-acyl serotonins identified in human intestinal tissue. | 2017 | Biochim. Biophys. Acta | pmid:28526351 |
| pmid:28528080 | ||||
| pmid:28529072 | ||||
| pmid:28538876 | ||||
| Luley C et al. | [Fatty acid composition and degree of peroxidation in fish oil and cod liver oil preparations]. | 1988 | Arzneimittelforschung | pmid:2854466 |
| pmid:28566634 | ||||
| pmid:28572562 | ||||
| pmid:28574453 |