Dha is a lipid of Fatty Acyls (FA) class. Dha is associated with abnormalities such as Atherosclerosis, Consumption-archaic term for TB, Chronic disease, Cardiovascular Diseases and Diabetes Mellitus, Non-Insulin-Dependent. The involved functions are known as Inflammation, Oxidation, fatty acid oxidation, Fatty Acid Metabolism and Lipid Metabolism. Dha often locates in Hepatic, Protoplasm, Mucous Membrane, Epithelium and outer membrane. The associated genes with DHA are IMPACT gene, FATE1 gene, GAPDH gene, THOC4 gene and SLC33A1 gene. The related lipids are stearidonic acid, Fatty Acids, Total cholesterol, Lipopolysaccharides and Dietary Fatty Acid. The related experimental models are Mouse Model, Transgenic Model, Animal Disease Models and Arthritis, Experimental.
To understand associated biological information of DHA, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
DHA is suspected in Cardiovascular Diseases, Obesity, Ischemia, Hypertensive disease, Coronary Arteriosclerosis, Cerebrovascular accident and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with DHA
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
Lipid concept | Cross reference | Weighted score | Related literatures |
---|
Gene | Cross reference | Weighted score | Related literatures |
---|
Mouse Model are used in the study 'Homeostatic regulation of photoreceptor cell integrity: significance of the potent mediator neuroprotectin D1 biosynthesized from docosahexaenoic acid: the Proctor Lecture.' (Bazan NG, 2007), Mouse Model are used in the study 'Omega-3 fatty acids EPA and DHA: health benefits throughout life.' (Swanson D et al., 2012), Mouse Model are used in the study 'Docosahexaenoic acid attenuates hepatic inflammation, oxidative stress, and fibrosis without decreasing hepatosteatosis in a Ldlr(-/-) mouse model of western diet-induced nonalcoholic steatohepatitis.' (Depner CM et al., 2013) and Mouse Model are used in the study 'Wax esters from the marine copepod Calanus finmarchicus reduce diet-induced obesity and obesity-related metabolic disorders in mice.' (Höper AC et al., 2014).
Transgenic Model are used in the study 'Loss of MAP function leads to hippocampal synapse loss and deficits in the Morris Water Maze with aging.' (Ma QL et al., 2014).
Animal Disease Models are used in the study 'Fish oil increases muscle protein mass and modulates Akt/FOXO, TLR4, and NOD signaling in weanling piglets after lipopolysaccharide challenge.' (Liu Y et al., 2013).
Model | Cross reference | Weighted score | Related literatures |
---|
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Vreugdenhil M et al. | Polyunsaturated fatty acids modulate sodium and calcium currents in CA1 neurons. | 1996 | Proc. Natl. Acad. Sci. U.S.A. | pmid:8901621 |
Hoshi T et al. | Omega-3 fatty acids lower blood pressure by directly activating large-conductance Ca²âº-dependent K⺠channels. | 2013 | Proc. Natl. Acad. Sci. U.S.A. | pmid:23487785 |
Hoshi T et al. | Mechanism of the modulation of BK potassium channel complexes with different auxiliary subunit compositions by the omega-3 fatty acid DHA. | 2013 | Proc. Natl. Acad. Sci. U.S.A. | pmid:23487786 |
Mukherjee PK et al. | Photoreceptor outer segment phagocytosis attenuates oxidative stress-induced apoptosis with concomitant neuroprotectin D1 synthesis. | 2007 | Proc. Natl. Acad. Sci. U.S.A. | pmid:17670935 |
Scott BL and Bazan NG | Membrane docosahexaenoate is supplied to the developing brain and retina by the liver. | 1989 | Proc. Natl. Acad. Sci. U.S.A. | pmid:2523075 |
Krishnamoorthy S et al. | Resolvin D1 binds human phagocytes with evidence for proresolving receptors. | 2010 | Proc. Natl. Acad. Sci. U.S.A. | pmid:20080636 |
Mukherjee PK et al. | Neuroprotectin D1: a docosahexaenoic acid-derived docosatriene protects human retinal pigment epithelial cells from oxidative stress. | 2004 | Proc. Natl. Acad. Sci. U.S.A. | pmid:15152078 |
Berger A et al. | Anandamide and diet: inclusion of dietary arachidonate and docosahexaenoate leads to increased brain levels of the corresponding N-acylethanolamines in piglets. | 2001 | Proc. Natl. Acad. Sci. U.S.A. | pmid:11353819 |
Corey EJ et al. | Docosahexaenoic acid is a strong inhibitor of prostaglandin but not leukotriene biosynthesis. | 1983 | Proc. Natl. Acad. Sci. U.S.A. | pmid:6304720 |
Kang JX et al. | Free, long-chain, polyunsaturated fatty acids reduce membrane electrical excitability in neonatal rat cardiac myocytes. | 1995 | Proc. Natl. Acad. Sci. U.S.A. | pmid:7732020 |
Akbar M et al. | Docosahexaenoic acid: a positive modulator of Akt signaling in neuronal survival. | 2005 | Proc. Natl. Acad. Sci. U.S.A. | pmid:16040805 |
Ruyle M et al. | Placental transfer of essential fatty acids in humans: venous-arterial difference for docosahexaenoic acid in fetal umbilical erythrocytes. | 1990 | Proc. Natl. Acad. Sci. U.S.A. | pmid:2146677 |
Honoré E et al. | External blockade of the major cardiac delayed-rectifier K+ channel (Kv1.5) by polyunsaturated fatty acids. | 1994 | Proc. Natl. Acad. Sci. U.S.A. | pmid:8127910 |
Bruno MJ et al. | Docosahexaenoic acid alters bilayer elastic properties. | 2007 | Proc. Natl. Acad. Sci. U.S.A. | pmid:17535898 |
Nishio K et al. | Novel water-soluble derivatives of docosahexaenoic acid increase diacylglycerol production mediated by phosphatidylcholine-specific phospholipase C. | 1993 | Proc. Soc. Exp. Biol. Med. | pmid:8389049 |
Engler MM et al. | Docosahexaenoic acid is an antihypertensive nutrient that affects aldosterone production in SHR. | 1999 | Proc. Soc. Exp. Biol. Med. | pmid:10320629 |
Jenski LJ et al. | Omega-3 fatty acid-containing liposomes in cancer therapy. | 1995 | Proc. Soc. Exp. Biol. Med. | pmid:8539260 |
Uauy-Dagach R and Valenzuela A | Marine oils as a source of omega-3 fatty acids in the diet: how to optimize the health benefits. | 1992 | Prog Food Nutr Sci | pmid:1438808 |
Judé S et al. | Dietary long-chain omega-3 fatty acids of marine origin: a comparison of their protective effects on coronary heart disease and breast cancers. | 2006 Jan-Apr | Prog. Biophys. Mol. Biol. | pmid:16005051 |
Wetzel MG et al. | Fatty acid metabolism in normal miniature poodles and those affected with progressive rod-cone degeneration (prcd). | 1989 | Prog. Clin. Biol. Res. | pmid:2532748 |
Karanian JW et al. | Cardiovascular properties of hydroxylated docosahexaenoates. | 1989 | Prog. Clin. Biol. Res. | pmid:2529554 |
Bazan NG | The metabolism of omega-3 polyunsaturated fatty acids in the eye: the possible role of docosahexaenoic acid and docosanoids in retinal physiology and ocular pathology. | 1989 | Prog. Clin. Biol. Res. | pmid:2529559 |
Martinez M | Treatment with docosahexaenoic acid favorably modifies the fatty acid composition of erythrocytes in peroxisomal patients. | 1992 | Prog. Clin. Biol. Res. | pmid:1438383 |
Huang WH et al. | Control of the sodium pump by liponucleotides and unsaturated fatty acids: side-dependent effects in red cells. | 1988 | Prog. Clin. Biol. Res. | pmid:2851818 |
Organisciak DT et al. | Aspects of the ascorbate protective mechanism in retinal light damage of rats with normal and reduced ROS docosahexaenoic acid. | 1987 | Prog. Clin. Biol. Res. | pmid:2960984 |
Barceló-Coblijn G and Murphy EJ | Alpha-linolenic acid and its conversion to longer chain n-3 fatty acids: benefits for human health and a role in maintaining tissue n-3 fatty acid levels. | 2009 | Prog. Lipid Res. | pmid:19619583 |
Frisardi V et al. | Glycerophospholipids and glycerophospholipid-derived lipid mediators: a complex meshwork in Alzheimer's disease pathology. | 2011 | Prog. Lipid Res. | pmid:21703303 |
Cunnane SC et al. | Fish, docosahexaenoic acid and Alzheimer's disease. | 2009 | Prog. Lipid Res. | pmid:19362576 |
Bougnoux P et al. | Fatty acids and breast cancer: sensitization to treatments and prevention of metastatic re-growth. | 2010 | Prog. Lipid Res. | pmid:19715726 |
Valentine RC and Valentine DL | Omega-3 fatty acids in cellular membranes: a unified concept. | 2004 | Prog. Lipid Res. | pmid:15458813 |
Giusto NM et al. | Lipid metabolism in vertebrate retinal rod outer segments. | 2000 | Prog. Lipid Res. | pmid:10856601 |
Elsherbiny ME et al. | Interaction of brain fatty acid-binding protein with the polyunsaturated fatty acid environment as a potential determinant of poor prognosis in malignant glioma. | 2013 | Prog. Lipid Res. | pmid:23981365 |
Poudyal H et al. | Omega-3 fatty acids and metabolic syndrome: effects and emerging mechanisms of action. | 2011 | Prog. Lipid Res. | pmid:21762726 |
Lauritzen L et al. | The essentiality of long chain n-3 fatty acids in relation to development and function of the brain and retina. | 2001 Jan-Mar | Prog. Lipid Res. | pmid:11137568 |
Venegas-Calerón M et al. | An alternative to fish oils: Metabolic engineering of oil-seed crops to produce omega-3 long chain polyunsaturated fatty acids. | 2010 | Prog. Lipid Res. | pmid:19857520 |
Domenichiello AF et al. | Is docosahexaenoic acid synthesis from α-linolenic acid sufficient to supply the adult brain? | 2015 | Prog. Lipid Res. | pmid:25920364 |
Ramos-Loyo J et al. | Sex differences in lipid peroxidation and fatty acid levels in recent onset schizophrenia. | 2013 | Prog. Neuropsychopharmacol. Biol. Psychiatry | pmid:23421976 |
Doornbos B et al. | The development of peripartum depressive symptoms is associated with gene polymorphisms of MAOA, 5-HTT and COMT. | 2009 | Prog. Neuropsychopharmacol. Biol. Psychiatry | pmid:19625011 |
Buydens-Branchey L et al. | Associations between increases in plasma n-3 polyunsaturated fatty acids following supplementation and decreases in anger and anxiety in substance abusers. | 2008 | Prog. Neuropsychopharmacol. Biol. Psychiatry | pmid:18060675 |
Blanchet J et al. | Resveratrol, a red wine polyphenol, protects dopaminergic neurons in MPTP-treated mice. | 2008 | Prog. Neuropsychopharmacol. Biol. Psychiatry | pmid:18471948 |
Doornbos B et al. | Supplementation of a low dose of DHA or DHA+AA does not prevent peripartum depressive symptoms in a small population based sample. | 2009 | Prog. Neuropsychopharmacol. Biol. Psychiatry | pmid:18955102 |
Blachier F et al. | Arachidonic acid metabolism and casein secretion in lactating rabbit mammary epithelial cells: effects of inhibitors of prostaglandins and leukotrienes synthesis. | 1988 | Prostaglandins | pmid:2834771 |
Kim HY and Salem N | Preparation and the structural determination of hydroperoxy derivatives of docosahexaenoic acid and other polyunsaturates by thermospray LC/MS. | 1989 | Prostaglandins | pmid:2541468 |
Mai J et al. | A new prostaglandin, C22-PGF4 alpha, synthesized from docosahexaenoic acid (C22:6n3) by trout gill. | 1981 | Prostaglandins | pmid:6280241 |
Kim HY et al. | Stereochemical analysis of hydroxylated docosahexaenoates produced by human platelets and rat brain homogenate. | 1990 | Prostaglandins | pmid:2147773 |
Kim HY et al. | Formation of 15-lipoxygenase product from docosahexaenoic acid (22:6w3) by human platelets. | 1990 | Prostaglandins | pmid:2147774 |
Fischer S et al. | Dietary docosahexaenoic acid is retroconverted in man to eicosapentaenoic acid, which can be quickly transformed to prostaglandin I3. | 1987 | Prostaglandins | pmid:2829279 |
Hishinuma T et al. | Microdetermination of the thromboxane B3 gas chromatography-selected-ion monitoring using [18O]thromboxane B3 as an internal standard. | 1997 | Prostaglandins | pmid:9261859 |
Claeys M et al. | Diacylglycerols interfere in normal phase HPLC analysis of lipoxygenase products of docosahexaenoic or arachidonic acids. | 1986 | Prostaglandins | pmid:2951768 |
Agren JJ et al. | Hemostatic factors and platelet aggregation after a fish-enriched diet or fish oil or docosahexaenoic acid supplementation. | 1997 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:9430389 |
Reardon HT et al. | Dietary long-chain polyunsaturated fatty acids upregulate expression of FADS3 transcripts. | 2013 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:22398025 |
Chen ZY and Istfan NW | Docosahexaenoic acid, a major constituent of fish oil diets, prevents activation of cyclin-dependent kinases and S-phase entry by serum stimulation in HT-29 cells. | 2001 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:11161587 |
Ott J et al. | Lipids in critical care medicine. | 2011 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:21546231 |
Al-Turkmani MR et al. | Fatty acid alterations and n-3 fatty acid supplementation in cystic fibrosis. | 2007 Nov-Dec | Prostaglandins Leukot. Essent. Fatty Acids | pmid:18036797 |
Brenna T et al. | Docosahexaenoic acid in translational medicine: the Tenth Fatty Acids and Cell Signaling meeting (FACS-10). | 2013 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:23103099 |
Hashimoto M et al. | Effects of aging on the relation of adenyl purine release with plasma membrane fluidity of arterial endothelial cells. | 2005 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:16165346 |
Lii CK et al. | Effect of dietary lipid on gamma-glutamyl transferase-positive foci during hepatocarcinogenesis in rats. | 1998 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:9774170 |
Hsieh AT and Brenna JT | Dietary docosahexaenoic acid but not arachidonic acid influences central nervous system fatty acid status in baboon neonates. | 2009 Aug-Sep | Prostaglandins Leukot. Essent. Fatty Acids | pmid:19524425 |
Whelan J et al. | Docosahexaenoic acid: measurements in food and dietary exposure. | 2009 Aug-Sep | Prostaglandins Leukot. Essent. Fatty Acids | pmid:19493663 |
Makrides M | Is there a dietary requirement for DHA in pregnancy? | 2009 Aug-Sep | Prostaglandins Leukot. Essent. Fatty Acids | pmid:19500960 |
Schuchardt JP et al. | Moderate doses of EPA and DHA from re-esterified triacylglycerols but not from ethyl-esters lower fasting serum triacylglycerols in statin-treated dyslipidemic subjects: Results from a six month randomized controlled trial. | 2011 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:21862301 |
Lien EL | Toxicology and safety of DHA. | 2009 Aug-Sep | Prostaglandins Leukot. Essent. Fatty Acids | pmid:19501496 |
Chen CT et al. | Rapid beta-oxidation of eicosapentaenoic acid in mouse brain: an in situ study. | 2009 Feb-Mar | Prostaglandins Leukot. Essent. Fatty Acids | pmid:19237271 |
Nieminen LR et al. | Relationship between omega-3 fatty acids and plasma neuroactive steroids in alcoholism, depression and controls. | 2006 Oct-Nov | Prostaglandins Leukot. Essent. Fatty Acids | pmid:16959481 |
Marsen TA et al. | Pharmacokinetics of omega-3-fatty acids during ingestion of fish oil preparations. | 1992 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:1387231 |
Kuratko CN and Salem N | Biomarkers of DHA status. | 2009 Aug-Sep | Prostaglandins Leukot. Essent. Fatty Acids | pmid:19545987 |
Holub BJ | Docosahexaenoic acid (DHA) and cardiovascular disease risk factors. | 2009 Aug-Sep | Prostaglandins Leukot. Essent. Fatty Acids | pmid:19545988 |
Lagarde M et al. | Dose-effect and metabolism of docosahexaenoic acid: pathophysiological relevance in blood platelets. | 2013 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:22520055 |
Mohan IK and Das UN | Oxidant stress, anti-oxidants and essential fatty acids in systemic lupus erythematosus. | 1997 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:9089797 |
Russell KL et al. | Low brain DHA content worsens sensorimotor outcomes after TBI and decreases TBI-induced Timp1 expression in juvenile rats. | 2013 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:23796971 |
Horrocks LA and Farooqui AA | Docosahexaenoic acid in the diet: its importance in maintenance and restoration of neural membrane function. | 2004 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:15041028 |
Kurowska EM et al. | Bioavailability of omega-3 essential fatty acids from perilla seed oil. | 2003 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:12591004 |
Erdogan H et al. | Effect of fish oil supplementation on plasma oxidant/antioxidant status in rats. | 2004 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:15253883 |
Krabbendam L et al. | Relationship between DHA status at birth and child problem behaviour at 7 years of age. | 2007 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:17074476 |
Qin X et al. | Brown but not white adipose cells synthesize omega-3 docosahexaenoic acid in culture. | 2016 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:26802938 |
Brenner RR | Hormonal modulation of delta6 and delta5 desaturases: case of diabetes. | 2003 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:12538079 |
Kim HY et al. | Phosphatidylserine-dependent neuroprotective signaling promoted by docosahexaenoic acid. | 2010 Apr-Jun | Prostaglandins Leukot. Essent. Fatty Acids | pmid:20207120 |
Minns LM et al. | Toddler formula supplemented with docosahexaenoic acid (DHA) improves DHA status and respiratory health in a randomized, double-blind, controlled trial of US children less than 3 years of age. | 2010 Apr-Jun | Prostaglandins Leukot. Essent. Fatty Acids | pmid:20207123 |
Sarri KO et al. | Adipose DHA inversely associated with depression as measured by the Beck Depression Inventory. | 2008 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:18258421 |
McPhee S et al. | Prophylactic and therapeutic effects of Mytilus edulis fatty acids on adjuvant-induced arthritis in male Wistar rats. | 2010 Feb-Mar | Prostaglandins Leukot. Essent. Fatty Acids | pmid:20074924 |
Agostoni C et al. | Biochemical effects of supplemented long-chain polyunsaturated fatty acids in hyperphenylalaninemia. | 2001 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:11237478 |
Zhou D et al. | Vitamin A deficiency reduces liver and colon docosahexaenoic acid levels in rats fed high linoleic and low alpha-linolenic acid diet. | 2004 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:15519497 |
Schuchardt JP and Hahn A | Bioavailability of long-chain omega-3 fatty acids. | 2013 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:23676322 |
Kitson AP et al. | Treatment of ovariectomized rats with 17β-estradiol increases hepatic delta-6 desaturase enzyme expression and docosahexaenoic acid levels in hepatic and plasma phospholipids. | 2013 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:23764042 |
Baskaya MK et al. | Enhanced accumulation of free fatty acids in experimental focal cerebral ischemia. | 1996 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:8860103 |
Rapoport SI | Translational studies on regulation of brain docosahexaenoic acid (DHA) metabolism in vivo. | 2013 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:22766388 |
Burdge GC et al. | The effect of altering the 20:5n-3 and 22:6n-3 content of a meal on the postprandial incorporation of n-3 polyunsaturated fatty acids into plasma triacylglycerol and non-esterified fatty acids in humans. | 2007 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:17693069 |
Murali G et al. | Differential effects of eicosapentaenoic acid and docosahexaenoic acid in promoting the differentiation of 3T3-L1 preadipocytes. | 2014 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:24332315 |
Engler MM et al. | The effects of a diet rich in docosahexaenoic acid on organ and vascular fatty acid composition in spontaneously hypertensive rats. | 1999 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:10670690 |
Calder PC | Immunomodulation by omega-3 fatty acids. | 2007 Nov-Dec | Prostaglandins Leukot. Essent. Fatty Acids | pmid:18032006 |
Leaf A | Omega-3 fatty acids and prevention of ventricular fibrillation. | 1995 Feb-Mar | Prostaglandins Leukot. Essent. Fatty Acids | pmid:7784457 |
van Goor SA et al. | Maternal and fetal brain contents of docosahexaenoic acid (DHA) and arachidonic acid (AA) at various essential fatty acid (EFA), DHA and AA dietary intakes during pregnancy in mice. | 2008 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:18343099 |
Helmersson-Karlqvist J et al. | Enhanced prostaglandin F2α formation in human pregnancy and the effect of increased oily fish intake: results from the Salmon in Pregnancy Study. | 2012 Jan-Feb | Prostaglandins Leukot. Essent. Fatty Acids | pmid:22047909 |
Taha AY et al. | Threshold changes in rat brain docosahexaenoic acid incorporation and concentration following graded reductions in dietary alpha-linolenic acid. | 2016 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:26869088 |
Larson MK et al. | Omega-3 fatty acids modulate collagen signaling in human platelets. | 2011 Mar-Apr | Prostaglandins Leukot. Essent. Fatty Acids | pmid:21177087 |
Dhobale MV et al. | Reduced levels of placental long chain polyunsaturated fatty acids in preterm deliveries. | 2011 Sep-Oct | Prostaglandins Leukot. Essent. Fatty Acids | pmid:21816593 |
Harmon SD et al. | Oxygenation of omega-3 fatty acids by human cytochrome P450 4F3B: effect on 20-hydroxyeicosatetraenoic acid production. | 2006 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:16820285 |
Marzo I et al. | Loss of delta6-desaturase activity leads to impaired docosahexaenoic acid synthesis in Y-79 retinoblastoma cells. | 1998 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:9888202 |
Yusof HM et al. | Influence of very long-chain n-3 fatty acids on plasma markers of inflammation in middle-aged men. | 2008 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:18403189 |
Frøyland L et al. | Hypotriacylglycerolemic component of fish oil. | 1997 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:9430383 |