| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hypothyroidism | D007037 | 32 associated lipids |
| Vision Disorders | D014786 | 10 associated lipids |
| Melanoma | D008545 | 69 associated lipids |
| Pain, Postoperative | D010149 | 13 associated lipids |
| Asthma | D001249 | 52 associated lipids |
| Kidney Diseases | D007674 | 29 associated lipids |
| Weight Gain | D015430 | 101 associated lipids |
| Hypersensitivity, Delayed | D006968 | 43 associated lipids |
| Glioma | D005910 | 112 associated lipids |
| Cell Transformation, Neoplastic | D002471 | 126 associated lipids |
DHA
Dha is a lipid of Fatty Acyls (FA) class. Dha is associated with abnormalities such as Atherosclerosis, Consumption-archaic term for TB, Chronic disease, Cardiovascular Diseases and Diabetes Mellitus, Non-Insulin-Dependent. The involved functions are known as Inflammation, Oxidation, fatty acid oxidation, Fatty Acid Metabolism and Lipid Metabolism. Dha often locates in Hepatic, Protoplasm, Mucous Membrane, Epithelium and outer membrane. The associated genes with DHA are IMPACT gene, FATE1 gene, GAPDH gene, THOC4 gene and SLC33A1 gene. The related lipids are stearidonic acid, Fatty Acids, Total cholesterol, Lipopolysaccharides and Dietary Fatty Acid. The related experimental models are Mouse Model, Transgenic Model, Animal Disease Models and Arthritis, Experimental.
Cross Reference
Introduction
To understand associated biological information of DHA, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with DHA?
DHA is suspected in Cardiovascular Diseases, Obesity, Ischemia, Hypertensive disease, Coronary Arteriosclerosis, Cerebrovascular accident and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with DHA
PubChem Associated disorders and diseases
What pathways are associated with DHA
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with DHA?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with DHA?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with DHA?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with DHA?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with DHA?
Mouse Model
Mouse Model are used in the study 'Homeostatic regulation of photoreceptor cell integrity: significance of the potent mediator neuroprotectin D1 biosynthesized from docosahexaenoic acid: the Proctor Lecture.' (Bazan NG, 2007), Mouse Model are used in the study 'Omega-3 fatty acids EPA and DHA: health benefits throughout life.' (Swanson D et al., 2012), Mouse Model are used in the study 'Docosahexaenoic acid attenuates hepatic inflammation, oxidative stress, and fibrosis without decreasing hepatosteatosis in a Ldlr(-/-) mouse model of western diet-induced nonalcoholic steatohepatitis.' (Depner CM et al., 2013) and Mouse Model are used in the study 'Wax esters from the marine copepod Calanus finmarchicus reduce diet-induced obesity and obesity-related metabolic disorders in mice.' (Höper AC et al., 2014).
Transgenic Model
Transgenic Model are used in the study 'Loss of MAP function leads to hippocampal synapse loss and deficits in the Morris Water Maze with aging.' (Ma QL et al., 2014).
Animal Disease Models
Animal Disease Models are used in the study 'Fish oil increases muscle protein mass and modulates Akt/FOXO, TLR4, and NOD signaling in weanling piglets after lipopolysaccharide challenge.' (Liu Y et al., 2013).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with DHA
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Agren JJ et al. | Hemostatic factors and platelet aggregation after a fish-enriched diet or fish oil or docosahexaenoic acid supplementation. | 1997 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:9430389 |
| Chen ZY and Istfan NW | Docosahexaenoic acid, a major constituent of fish oil diets, prevents activation of cyclin-dependent kinases and S-phase entry by serum stimulation in HT-29 cells. | 2001 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:11161587 |
| Yi SH et al. | A randomized, placebo-controlled, double-blind trial of supplemental docosahexaenoic acid on cognitive processing speed and executive function in females of reproductive age with phenylketonuria: A pilot study. | 2011 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:22000478 |
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| Ott J et al. | Lipids in critical care medicine. | 2011 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:21546231 |
| Kuipers RS et al. | High contents of both docosahexaenoic and arachidonic acids in milk of women consuming fish from lake Kitangiri (Tanzania): targets for infant formulae close to our ancient diet? | 2005 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:15763440 |
| An WS et al. | Effect of omega-3 fatty acids on the modification of erythrocyte membrane fatty acid content including oleic acid in peritoneal dialysis patients. | 2012 Jan-Feb | Prostaglandins Leukot. Essent. Fatty Acids | pmid:22071008 |
| Lii CK et al. | Effect of dietary lipid on gamma-glutamyl transferase-positive foci during hepatocarcinogenesis in rats. | 1998 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:9774170 |
| Cunnane SC | Commentary on the workshop statement. Essentiality of and recommended dietary intakes for Omega-6 and Omega-3 fatty acids. | 2000 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:10991770 |
| Burdge GC | Metabolism of alpha-linolenic acid in humans. | 2006 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:16828546 |
| Chen CT et al. | Rapid beta-oxidation of eicosapentaenoic acid in mouse brain: an in situ study. | 2009 Feb-Mar | Prostaglandins Leukot. Essent. Fatty Acids | pmid:19237271 |
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| Marsen TA et al. | Pharmacokinetics of omega-3-fatty acids during ingestion of fish oil preparations. | 1992 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:1387231 |
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| Green P et al. | Arachidonic acid-containing phosphatidylcholine species are increased in selected brain regions of a depressive animal model: implications for pathophysiology. | 2009 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:19342208 |
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| Peet M et al. | Essential fatty acid deficiency in erythrocyte membranes from chronic schizophrenic patients, and the clinical effects of dietary supplementation. | 1996 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:8888126 |
| Mueller MJ | Isoprostane nomenclature: inherent problems may cause setbacks for the development of the isoprostanoid field. | 2010 Feb-Mar | Prostaglandins Leukot. Essent. Fatty Acids | pmid:20034775 |
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| Pottala JV et al. | Red blood cell fatty acids are associated with depression in a case-control study of adolescents. | 2012 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:22464051 |
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| Kuipers RS et al. | Milk in the island of Chole [Tanzania] is high in lauric, myristic, arachidonic and docosahexaenoic acids, and low in linoleic acid reconstructed diet of infants born to our ancestors living in tropical coastal regions. | 2007 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:17383169 |
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| Abbate R et al. | n-3 PUFA supplementation, monocyte PCA expression and interleukin-6 production. | 1996 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:8888356 |
| Marzo I et al. | Loss of delta6-desaturase activity leads to impaired docosahexaenoic acid synthesis in Y-79 retinoblastoma cells. | 1998 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:9888202 |
| Frøyland L et al. | Hypotriacylglycerolemic component of fish oil. | 1997 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:9430383 |