| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hypothyroidism | D007037 | 32 associated lipids |
| Vision Disorders | D014786 | 10 associated lipids |
| Melanoma | D008545 | 69 associated lipids |
| Pain, Postoperative | D010149 | 13 associated lipids |
| Asthma | D001249 | 52 associated lipids |
| Kidney Diseases | D007674 | 29 associated lipids |
| Weight Gain | D015430 | 101 associated lipids |
| Hypersensitivity, Delayed | D006968 | 43 associated lipids |
| Glioma | D005910 | 112 associated lipids |
| Cell Transformation, Neoplastic | D002471 | 126 associated lipids |
DHA
Dha is a lipid of Fatty Acyls (FA) class. Dha is associated with abnormalities such as Atherosclerosis, Consumption-archaic term for TB, Chronic disease, Cardiovascular Diseases and Diabetes Mellitus, Non-Insulin-Dependent. The involved functions are known as Inflammation, Oxidation, fatty acid oxidation, Fatty Acid Metabolism and Lipid Metabolism. Dha often locates in Hepatic, Protoplasm, Mucous Membrane, Epithelium and outer membrane. The associated genes with DHA are IMPACT gene, FATE1 gene, GAPDH gene, THOC4 gene and SLC33A1 gene. The related lipids are stearidonic acid, Fatty Acids, Total cholesterol, Lipopolysaccharides and Dietary Fatty Acid. The related experimental models are Mouse Model, Transgenic Model, Animal Disease Models and Arthritis, Experimental.
Cross Reference
Introduction
To understand associated biological information of DHA, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with DHA?
DHA is suspected in Cardiovascular Diseases, Obesity, Ischemia, Hypertensive disease, Coronary Arteriosclerosis, Cerebrovascular accident and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with DHA
PubChem Associated disorders and diseases
What pathways are associated with DHA
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with DHA?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with DHA?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with DHA?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with DHA?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with DHA?
Mouse Model
Mouse Model are used in the study 'Homeostatic regulation of photoreceptor cell integrity: significance of the potent mediator neuroprotectin D1 biosynthesized from docosahexaenoic acid: the Proctor Lecture.' (Bazan NG, 2007), Mouse Model are used in the study 'Omega-3 fatty acids EPA and DHA: health benefits throughout life.' (Swanson D et al., 2012), Mouse Model are used in the study 'Docosahexaenoic acid attenuates hepatic inflammation, oxidative stress, and fibrosis without decreasing hepatosteatosis in a Ldlr(-/-) mouse model of western diet-induced nonalcoholic steatohepatitis.' (Depner CM et al., 2013) and Mouse Model are used in the study 'Wax esters from the marine copepod Calanus finmarchicus reduce diet-induced obesity and obesity-related metabolic disorders in mice.' (Höper AC et al., 2014).
Transgenic Model
Transgenic Model are used in the study 'Loss of MAP function leads to hippocampal synapse loss and deficits in the Morris Water Maze with aging.' (Ma QL et al., 2014).
Animal Disease Models
Animal Disease Models are used in the study 'Fish oil increases muscle protein mass and modulates Akt/FOXO, TLR4, and NOD signaling in weanling piglets after lipopolysaccharide challenge.' (Liu Y et al., 2013).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with DHA
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Mairesse G et al. | Effects of geographic source, rearing system, and season on the nutritional quality of wild and farmed Perca fluviatilis. | 2006 | Lipids | pmid:16711596 |
| Denys A et al. | Docosahexaenoic acid modulates phorbol ester-induced activation of extracellular signal-regulated kinases 1 and 2 in NIH/3T3 cells. | 2001 | Lipids | pmid:11592732 |
| Grandgirard A et al. | Occurrence of geometrical isomers of eicosapentaenoic and docosahexaenoic acids in liver lipids of rats fed heated linseed oil. | 1989 | Lipids | pmid:2555649 |
| Garrido A et al. | Ingestion of high doses of fish oil increases the susceptibility of cellular membranes to the induction of oxidative stress. | 1989 | Lipids | pmid:2555651 |
| Stamey Lanier J et al. | Mammary uptake of fatty acids supplied by intravenous triacylglycerol infusion to lactating dairy cows. | 2013 | Lipids | pmid:23504269 |
| Tardivel S et al. | Protective effects of EPA and deleterious effects of DHA on eNOS activity in Ea hy 926 cultured with lysophosphatidylcholine. | 2009 | Lipids | pmid:19190950 |
| Pasquier E et al. | Effects of delta5 polyunsaturated fatty acids of maritime pine (Pinus pinaster) seed oil on the fatty acid profile of the developing brain of rats. | 2001 | Lipids | pmid:11485159 |
| Makrides M et al. | Is dietary docosahexaenoic acid essential for term infants? | 1996 | Lipids | pmid:8649228 |
| Weisinger HS et al. | The effect of docosahexaenoic acid on the electroretinogram of the guinea pig. | 1996 | Lipids | pmid:8649236 |
| Carlson SE and Werkman SH | A randomized trial of visual attention of preterm infants fed docosahexaenoic acid until two months. | 1996 | Lipids | pmid:8649239 |
| Werkman SH and Carlson SE | A randomized trial of visual attention of preterm infants fed docosahexaenoic acid until nine months. | 1996 | Lipids | pmid:8649241 |
| Glozman S et al. | Ethyl docosahexaenoic acid administration during intrauterine life enhances prostanoid production and reduces free radicals generation in the fetal rat brain. | 1999 | Lipids | pmid:10419167 |
| Kim HY and Edsall L | The role of docosahexaenoic acid (22:6n-3) in neuronal signaling. | 1999 | Lipids | pmid:10419168 |
| Harris WS | n-3 fatty acids and human lipoprotein metabolism: an update. | 1999 | Lipids | pmid:10419172 |
| Howe PR et al. | Equal antithrombotic and triglyceride-lowering effectiveness of eicosapentaenoic acid-rich and docosahexaenoic acid-rich fish oil supplements. | 1999 | Lipids | pmid:10419186 |
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| Tanaka T et al. | Oral supplementation with dihomo-γ-linolenic acid (DGLA)-enriched oil increases serum DGLA content in healthy adults. | 2012 | Lipids | pmid:22411689 |
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| Degrace P et al. | Intestinal lymph absorption of butter, corn oil, cod liver oil, menhaden oil, and eicosapentaenoic and docosahexaenoic acid ethyl esters in rats. | 1996 | Lipids | pmid:8743053 |
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| Rotstein NP et al. | Effects of aging on the composition and metabolism of docosahexaenoate-containing lipids of retina. | 1987 | Lipids | pmid:2955190 |
| Baybutt RC et al. | The effects of dietary fish oil on alveolar type II cell fatty acids and lung surfactant phospholipids. | 1993 | Lipids | pmid:8464346 |
| Besson N et al. | Selective incorporation of docosahexaenoic acid into lysobisphosphatidic acid in cultured THP-1 macrophages. | 2006 | Lipids | pmid:17707985 |
| Kosugi Y et al. | Esterification of polyunsaturated fatty acids by various forms of immobilized lipase from Rhizomucor miehei. | 2000 | Lipids | pmid:10858032 |
| Tomobe YI et al. | Dietary docosahexaenoic acid suppresses inflammation and immunoresponses in contact hypersensitivity reaction in mice. | 2000 | Lipids | pmid:10695925 |
| Calviello G et al. | Low-dose eicosapentaenoic or docosahexaenoic acid administration modifies fatty acid composition and does not affect susceptibility to oxidative stress in rat erythrocytes and tissues. | 1997 | Lipids | pmid:9358434 |
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| Bell MV et al. | Dietary deficiency of docosahexaenoic acid impairs vision at low light intensities in juvenile herring (Clupea harengus L.). | 1995 | Lipids | pmid:7637565 |
| Oikawa D et al. | Dietary CLA and DHA modify skin properties in mice. | 2003 | Lipids | pmid:12934670 |
| Liu M et al. | Protectin DX, a double lipoxygenase product of DHA, inhibits both ROS production in human neutrophils and cyclooxygenase activities. | 2014 | Lipids | pmid:24254970 |
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