| MeSH term | MeSH ID | Detail |
|---|---|---|
| Dyslexia | D004410 | 3 associated lipids |
| Dysmenorrhea | D004412 | 9 associated lipids |
| Edema | D004487 | 152 associated lipids |
| Encephalomyelitis, Autoimmune, Experimental | D004681 | 26 associated lipids |
| Epilepsy | D004827 | 35 associated lipids |
| Erythema | D004890 | 22 associated lipids |
| Eye Abnormalities | D005124 | 7 associated lipids |
| Fatty Liver | D005234 | 48 associated lipids |
| Fatty Liver, Alcoholic | D005235 | 11 associated lipids |
| Fibrosis | D005355 | 23 associated lipids |
DHA
Dha is a lipid of Fatty Acyls (FA) class. Dha is associated with abnormalities such as Atherosclerosis, Consumption-archaic term for TB, Chronic disease, Cardiovascular Diseases and Diabetes Mellitus, Non-Insulin-Dependent. The involved functions are known as Inflammation, Oxidation, fatty acid oxidation, Fatty Acid Metabolism and Lipid Metabolism. Dha often locates in Hepatic, Protoplasm, Mucous Membrane, Epithelium and outer membrane. The associated genes with DHA are IMPACT gene, FATE1 gene, GAPDH gene, THOC4 gene and SLC33A1 gene. The related lipids are stearidonic acid, Fatty Acids, Total cholesterol, Lipopolysaccharides and Dietary Fatty Acid. The related experimental models are Mouse Model, Transgenic Model, Animal Disease Models and Arthritis, Experimental.
Cross Reference
Introduction
To understand associated biological information of DHA, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with DHA?
DHA is suspected in Cardiovascular Diseases, Obesity, Ischemia, Hypertensive disease, Coronary Arteriosclerosis, Cerebrovascular accident and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with DHA
PubChem Associated disorders and diseases
What pathways are associated with DHA
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with DHA?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with DHA?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with DHA?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with DHA?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with DHA?
Mouse Model
Mouse Model are used in the study 'Homeostatic regulation of photoreceptor cell integrity: significance of the potent mediator neuroprotectin D1 biosynthesized from docosahexaenoic acid: the Proctor Lecture.' (Bazan NG, 2007), Mouse Model are used in the study 'Omega-3 fatty acids EPA and DHA: health benefits throughout life.' (Swanson D et al., 2012), Mouse Model are used in the study 'Docosahexaenoic acid attenuates hepatic inflammation, oxidative stress, and fibrosis without decreasing hepatosteatosis in a Ldlr(-/-) mouse model of western diet-induced nonalcoholic steatohepatitis.' (Depner CM et al., 2013) and Mouse Model are used in the study 'Wax esters from the marine copepod Calanus finmarchicus reduce diet-induced obesity and obesity-related metabolic disorders in mice.' (Höper AC et al., 2014).
Transgenic Model
Transgenic Model are used in the study 'Loss of MAP function leads to hippocampal synapse loss and deficits in the Morris Water Maze with aging.' (Ma QL et al., 2014).
Animal Disease Models
Animal Disease Models are used in the study 'Fish oil increases muscle protein mass and modulates Akt/FOXO, TLR4, and NOD signaling in weanling piglets after lipopolysaccharide challenge.' (Liu Y et al., 2013).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
NCBI Entrez Crosslinks
All references with DHA
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Mustafa M et al. | Resolvin D1 protects periodontal ligament. | 2013 | Am. J. Physiol., Cell Physiol. | pmid:23864609 |
| Fiol-deRoque MA et al. | Cognitive recovery and restoration of cell proliferation in the dentate gyrus in the 5XFAD transgenic mice model of Alzheimer's disease following 2-hydroxy-DHA treatment. | 2013 | Biogerontology | pmid:24114505 |
| Isosapent ethyl (Vascepa) for severe hypertriglyceridemia. | 2013 | Med Lett Drugs Ther | pmid:23836343 | |
| Kasuya F et al. | Effect of the non-steroidal anti-inflammatory drugs on the acyl-CoA synthetase activity toward medium-chain, long-chain and polyunsaturated fatty acids in mitochondria of mouse liver and brain. | 2013 | J Enzyme Inhib Med Chem | pmid:22299587 |
| Sánchez-MartÃn MJ et al. | Improved conformational stability of the visual G protein-coupled receptor rhodopsin by specific interaction with docosahexaenoic acid phospholipid. | 2013 | Chembiochem | pmid:23447332 |
| Dacks PA et al. | Current evidence for the clinical use of long-chain polyunsaturated n-3 fatty acids to prevent age-related cognitive decline and Alzheimer's disease. | 2013 | J Nutr Health Aging | pmid:23459977 |
| Skilton MR et al. | High intake of dietary long-chain ω-3 fatty acids is associated with lower blood pressure in children born with low birth weight: NHANES 2003-2008. | 2013 | Hypertension | pmid:23460284 |
| Raatz SK et al. | Dose-dependent consumption of farmed Atlantic salmon (Salmo salar) increases plasma phospholipid n-3 fatty acids differentially. | 2013 | J Acad Nutr Diet | pmid:23351633 |
| Goustard-Langelier B et al. | Rat neural stem cell proliferation and differentiation are durably altered by the in utero polyunsaturated fatty acid supply. | 2013 | J. Nutr. Biochem. | pmid:23036607 |
| Harris WS et al. | Erythrocyte omega-3 fatty acids increase and linoleic acid decreases with age: observations from 160,000 patients. | 2013 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:23375840 |
| Kaur G et al. | Orally administered [¹â´C]DPA and [¹â´C]DHA are metabolised differently to [¹â´C]EPA in rats. | 2013 | Br. J. Nutr. | pmid:22578196 |
| Saha SS and Ghosh M | Protective effect of conjugated linolenic acid isomers present in vegetable oils against arsenite-induced renal toxicity in rat model. | 2013 | Nutrition | pmid:23422533 |
| Rahman MM et al. | DHA is a more potent inhibitor of breast cancer metastasis to bone and related osteolysis than EPA. | 2013 | Breast Cancer Res. Treat. | pmid:24062211 |
| Wijendran V et al. | Dietary arachidonic acid and docosahexaenoic acid regulate liver fatty acid desaturase (FADS) alternative transcript expression in suckling piglets. | 2013 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:24075244 |
| Liu X et al. | Oxidized fatty acid analysis by charge-switch derivatization, selected reaction monitoring, and accurate mass quantitation. | 2013 | Anal. Biochem. | pmid:23850559 |
| Fedor DM et al. | The effect of docosahexaenoic acid on t10, c12-conjugated linoleic acid-induced changes in fatty acid composition of mouse liver, adipose, and muscle. | 2013 | Metab Syndr Relat Disord | pmid:23170930 |
| Kuratko CN et al. | The relationship of docosahexaenoic acid (DHA) with learning and behavior in healthy children: a review. | 2013 | Nutrients | pmid:23877090 |
| Vigerust NF et al. | Krill oil versus fish oil in modulation of inflammation and lipid metabolism in mice transgenic for TNF-α. | 2013 | Eur J Nutr | pmid:22923017 |
| Marty-Roix R and Lien E | (De-) oiling inflammasomes. | 2013 | Immunity | pmid:23809158 |
| Yan Y et al. | Omega-3 fatty acids prevent inflammation and metabolic disorder through inhibition of NLRP3 inflammasome activation. | 2013 | Immunity | pmid:23809162 |
| Faxén-Irving G et al. | Effects on transthyretin in plasma and cerebrospinal fluid by DHA-rich n - 3 fatty acid supplementation in patients with Alzheimer's disease: the OmegAD study. | 2013 | J. Alzheimers Dis. | pmid:23563245 |
| Arnold C et al. | Macular xanthophylls and ω-3 long-chain polyunsaturated fatty acids in age-related macular degeneration: a randomized trial. | 2013 | JAMA Ophthalmol | pmid:23519529 |
| Guo B et al. | Identification and heterologous expression of a Δ4-fatty acid desaturase gene from Isochrysis sphaerica. | 2013 | J. Microbiol. Biotechnol. | pmid:23851273 |
| Oelrich B et al. | Effect of fish oil supplementation on serum triglycerides, LDL cholesterol and LDL subfractions in hypertriglyceridemic adults. | 2013 | Nutr Metab Cardiovasc Dis | pmid:21924882 |
| GarcÃa-Sastre A | Lessons from lipids in the fight against influenza. | 2013 | Cell | pmid:23827671 |
| Birch DG et al. | Spectral-domain optical coherence tomography measures of outer segment layer progression in patients with X-linked retinitis pigmentosa. | 2013 | JAMA Ophthalmol | pmid:23828615 |
| Aslan M et al. | LC-MS/MS analysis of plasma polyunsaturated fatty acids in type 2 diabetic patients after insulin analog initiation therapy. | 2013 | Lipids Health Dis | pmid:24195588 |
| Chen HF and Su HM | Exposure to a maternal n-3 fatty acid-deficient diet during brain development provokes excessive hypothalamic-pituitary-adrenal axis responses to stress and behavioral indices of depression and anxiety in male rat offspring later in life. | 2013 | J. Nutr. Biochem. | pmid:22818715 |
| Brahmbhatt V et al. | Protective effects of dietary EPA and DHA on ischemia-reperfusion-induced intestinal stress. | 2013 | J. Nutr. Biochem. | pmid:22819560 |
| Morel PC et al. | Effect of lipid type on growth performance, meat quality and the content of long chain n-3 fatty acids in pork meat. | 2013 | Meat Sci. | pmid:23739265 |
| Liu Y et al. | Fish oil increases muscle protein mass and modulates Akt/FOXO, TLR4, and NOD signaling in weanling piglets after lipopolysaccharide challenge. | 2013 | J. Nutr. | pmid:23739309 |
| Parletta N et al. | Effects of fish oil supplementation on learning and behaviour of children from Australian Indigenous remote community schools: a randomised controlled trial. | 2013 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:23756346 |
| Mortensen K and Tawia S | Sustained breastfeeding. | 2013 | Breastfeed Rev | pmid:23600325 |
| Harsløf LB et al. | FADS genotype and diet are important determinants of DHA status: a cross-sectional study in Danish infants. | 2013 | Am. J. Clin. Nutr. | pmid:23636240 |
| Kangari H et al. | Short-term consumption of oral omega-3 and dry eye syndrome. | 2013 | Ophthalmology | pmid:23642375 |
| Adler EM | Of fish oil, rafts, and scrambling things up. | 2013 | J. Gen. Physiol. | pmid:24277599 |
| Hashimoto M et al. | Prescription n-3 fatty acids, but not eicosapentaenoic acid alone, improve reference memory-related learning ability by increasing brain-derived neurotrophic factor levels in SHR.Cg-Lepr(cp)/NDmcr rats, a metabolic syndrome model. | 2013 | Neurochem. Res. | pmid:23963508 |
| Tabbaa M et al. | Docosahexaenoic acid, inflammation, and bacterial dysbiosis in relation to periodontal disease, inflammatory bowel disease, and the metabolic syndrome. | 2013 | Nutrients | pmid:23966110 |
| Crawford MA et al. | A quantum theory for the irreplaceable role of docosahexaenoic acid in neural cell signalling throughout evolution. | 2013 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:23206328 |
| Kim K et al. | A novel fed-batch process based on the biology of Aurantiochytrium sp. KRS101 for the production of biodiesel and docosahexaenoic acid. | 2013 | Bioresour. Technol. | pmid:23206808 |
| Pomponi M et al. | Plasma levels of n-3 fatty acids in bipolar patients: deficit restricted to DHA. | 2013 | J Psychiatr Res | pmid:23207113 |
| Köhnke T et al. | Acetylsalicylic Acid reduces the severity of dextran sodium sulfate-induced colitis and increases the formation of anti-inflammatory lipid mediators. | 2013 | Biomed Res Int | pmid:24083240 |
| LluÃs L et al. | Protective effect of the omega-3 polyunsaturated fatty acids: Eicosapentaenoic acid/Docosahexaenoic acid 1:1 ratio on cardiovascular disease risk markers in rats. | 2013 | Lipids Health Dis | pmid:24083393 |
| Valentine CJ et al. | Randomized controlled trial of docosahexaenoic acid supplementation in midwestern U.S. human milk donors. | 2013 | Breastfeed Med | pmid:22568471 |
| D'Souza V et al. | Counteracting oxidative stress in pregnancy through modulation of maternal micronutrients and omega-3 fatty acids. | 2013 | Curr. Med. Chem. | pmid:24274816 |
| Tomita T et al. | High concentrations of omega-3 fatty acids are associated with the development of atrial fibrillation in the Japanese population. | 2013 | Heart Vessels | pmid:22696184 |
| Bogl LH et al. | Association between habitual dietary intake and lipoprotein subclass profile in healthy young adults. | 2013 | Nutr Metab Cardiovasc Dis | pmid:23333726 |
| Gupta A et al. | Pollen baiting facilitates the isolation of marine thraustochytrids with potential in omega-3 and biodiesel production. | 2013 | J. Ind. Microbiol. Biotechnol. | pmid:23990167 |
| Satkunendrarajah K and Fehlings MG | Do omega-3 polyunsaturated fatty acids ameliorate spinal cord injury?: Commentary on: Lim et al., Improved outcome after spinal cord compression injury in mice treated with docosahexaeonic acid. Exp. Neurol. Jan; 239:13-27. | 2013 | Exp. Neurol. | pmid:23994716 |
| Li Y et al. | Plasticity of leukocytic exudates in resolving acute inflammation is regulated by MicroRNA and proresolving mediators. | 2013 | Immunity | pmid:24238341 |