DHA

Dha is a lipid of Fatty Acyls (FA) class. Dha is associated with abnormalities such as Atherosclerosis, Consumption-archaic term for TB, Chronic disease, Cardiovascular Diseases and Diabetes Mellitus, Non-Insulin-Dependent. The involved functions are known as Inflammation, Oxidation, fatty acid oxidation, Fatty Acid Metabolism and Lipid Metabolism. Dha often locates in Hepatic, Protoplasm, Mucous Membrane, Epithelium and outer membrane. The associated genes with DHA are IMPACT gene, FATE1 gene, GAPDH gene, THOC4 gene and SLC33A1 gene. The related lipids are stearidonic acid, Fatty Acids, Total cholesterol, Lipopolysaccharides and Dietary Fatty Acid. The related experimental models are Mouse Model, Transgenic Model, Animal Disease Models and Arthritis, Experimental.

Cross Reference

Introduction

To understand associated biological information of DHA, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with DHA?

DHA is suspected in Cardiovascular Diseases, Obesity, Ischemia, Hypertensive disease, Coronary Arteriosclerosis, Cerebrovascular accident and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with DHA

MeSH term MeSH ID Detail
Cardiomyopathy, Dilated D002311 15 associated lipids
Uveitis D014605 14 associated lipids
Biliary Atresia D001656 4 associated lipids
Cachexia D002100 21 associated lipids
Arthus Reaction D001183 8 associated lipids
Learning Disorders D007859 11 associated lipids
Retinitis Pigmentosa D012174 6 associated lipids
Angina Pectoris D000787 27 associated lipids
Angina, Unstable D000789 14 associated lipids
Vascular Diseases D014652 16 associated lipids
Pregnancy Complications, Hematologic D011250 11 associated lipids
Heart Defects, Congenital D006330 20 associated lipids
Listeriosis D008088 12 associated lipids
Anemia D000740 21 associated lipids
Infant, Premature, Diseases D007235 7 associated lipids
Hyperlipoproteinemias D006951 15 associated lipids
Fatty Liver, Alcoholic D005235 11 associated lipids
Keratitis D007634 7 associated lipids
Parkinson Disease D010300 53 associated lipids
Down Syndrome D004314 18 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with DHA

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with DHA?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with DHA?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with DHA?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with DHA?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with DHA?

Mouse Model

Mouse Model are used in the study 'Homeostatic regulation of photoreceptor cell integrity: significance of the potent mediator neuroprotectin D1 biosynthesized from docosahexaenoic acid: the Proctor Lecture.' (Bazan NG, 2007), Mouse Model are used in the study 'Omega-3 fatty acids EPA and DHA: health benefits throughout life.' (Swanson D et al., 2012), Mouse Model are used in the study 'Docosahexaenoic acid attenuates hepatic inflammation, oxidative stress, and fibrosis without decreasing hepatosteatosis in a Ldlr(-/-) mouse model of western diet-induced nonalcoholic steatohepatitis.' (Depner CM et al., 2013) and Mouse Model are used in the study 'Wax esters from the marine copepod Calanus finmarchicus reduce diet-induced obesity and obesity-related metabolic disorders in mice.' (Höper AC et al., 2014).

Transgenic Model

Transgenic Model are used in the study 'Loss of MAP function leads to hippocampal synapse loss and deficits in the Morris Water Maze with aging.' (Ma QL et al., 2014).

Animal Disease Models

Animal Disease Models are used in the study 'Fish oil increases muscle protein mass and modulates Akt/FOXO, TLR4, and NOD signaling in weanling piglets after lipopolysaccharide challenge.' (Liu Y et al., 2013).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with DHA

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Per page 10 20 50 100 | Total 7336
Authors Title Published Journal PubMed Link
Benassayag C et al. High polyunsaturated fatty acid, thromboxane A2, and alpha-fetoprotein concentrations at the human feto-maternal interface. 1997 J. Lipid Res. pmid:9162747
Green P et al. Replenishment of docosahexaenoic acid in n-3 fatty acid-deficient fetal rats by intraamniotic ethyl-docosahexaenoate administration. 1997 J. Neurosci. Res. pmid:9160249
Buzzi M et al. Biosynthesis of docosahexaenoic acid in trout hepatocytes proceeds via 24-carbon intermediates. 1997 Comp. Biochem. Physiol. B, Biochem. Mol. Biol. pmid:9159889
Andreassen AK et al. Hypertension prophylaxis with omega-3 fatty acids in heart transplant recipients. 1997 J. Am. Coll. Cardiol. pmid:9137231
Gordon N Nutrition and cognitive function. 1997 Brain Dev. pmid:9134186
Oski FA What we eat may determine who we can be. 1997 Nutrition pmid:9131682
Harris WS n-3 fatty acids and serum lipoproteins: human studies. 1997 Am. J. Clin. Nutr. pmid:9129504
Tamura M and Suzuki H Effect of docosahexaenoic acid and linoleic acid diets on the ultrastructure of liver cells in adult mice. 1997 Int J Vitam Nutr Res pmid:9129257
Heird WC et al. Docosahexaenoic acid and the development and function of the infant retina. 1997 Curr. Opin. Lipidol. pmid:9127705
Khalfoun B et al. In vitro effects of docosahexaenoic and eicosapentaenoic acids in association with cyclosporine A on human lymphocyte proliferation. 1997 Feb-Mar Transplant. Proc. pmid:9123309
Kikugawa K et al. beta-Carotene effectively scavenges toxic nitrogen oxides: nitrogen dioxide and peroxynitrous acid. 1997 FEBS Lett. pmid:9119059
Ndiaye J and Hayashi S Effect of docosahexaenoic acid on lipoprotein synthesis and secretion by cultured eel hepatocytes. 1996 Cell Struct. Funct. pmid:9118236
Mandell IB et al. Effects of fish meal in beef cattle diets on growth performance, carcass characteristics, and fatty acid composition of longissimus muscle. 1997 J. Anim. Sci. pmid:9110201
McKeone BJ et al. Alterations in serum phosphatidylcholine fatty acyl species by eicosapentaenoic and docosahexaenoic ethyl esters in patients with severe hypertriglyceridemia. 1997 J. Lipid Res. pmid:9101424
Rodriguez de Turco EB et al. Post-Golgi vesicles cotransport docosahexaenoyl-phospholipids and rhodopsin during frog photoreceptor membrane biogenesis. 1997 J. Biol. Chem. pmid:9099692
Mohan IK and Das UN Oxidant stress, anti-oxidants and essential fatty acids in systemic lupus erythematosus. 1997 Prostaglandins Leukot. Essent. Fatty Acids pmid:9089797
Bouglé D et al. Relationships between red blood cell vitamin E and polyunsaturated fatty acid in the premature infant. 1996 Ann. Nutr. Metab. pmid:9087310
Conquer JA and Holub BJ Dietary docosahexaenoic acid as a source of eicosapentaenoic acid in vegetarians and omnivores. 1997 Lipids pmid:9076673
Atkinson TG et al. Incorporation of long-chain n-3 fatty acids in tissues and enhanced bone marrow cellularity with docosahexaenoic acid feeding in post-weanling Fischer 344 rats. 1997 Lipids pmid:9076666
Kimura S et al. Dietary docosahexaenoic acid (22: 6n-3) prevents the development of hypertension in SHRSP. 1995 Clin Exp Pharmacol Physiol Suppl pmid:9072405