| MeSH term | MeSH ID | Detail |
|---|---|---|
| Leukemia, Basophilic, Acute | D015471 | 9 associated lipids |
| Bone Diseases, Metabolic | D001851 | 9 associated lipids |
| Retinal Detachment | D012163 | 10 associated lipids |
| Vision Disorders | D014786 | 10 associated lipids |
| Colorectal Neoplasms | D015179 | 10 associated lipids |
| Asthma, Exercise-Induced | D001250 | 10 associated lipids |
| Pneumonia | D011014 | 10 associated lipids |
| Long QT Syndrome | D008133 | 10 associated lipids |
| Dry Eye Syndromes | D015352 | 10 associated lipids |
| Central Nervous System Diseases | D002493 | 10 associated lipids |
DHA
Dha is a lipid of Fatty Acyls (FA) class. Dha is associated with abnormalities such as Atherosclerosis, Consumption-archaic term for TB, Chronic disease, Cardiovascular Diseases and Diabetes Mellitus, Non-Insulin-Dependent. The involved functions are known as Inflammation, Oxidation, fatty acid oxidation, Fatty Acid Metabolism and Lipid Metabolism. Dha often locates in Hepatic, Protoplasm, Mucous Membrane, Epithelium and outer membrane. The associated genes with DHA are IMPACT gene, FATE1 gene, GAPDH gene, THOC4 gene and SLC33A1 gene. The related lipids are stearidonic acid, Fatty Acids, Total cholesterol, Lipopolysaccharides and Dietary Fatty Acid. The related experimental models are Mouse Model, Transgenic Model, Animal Disease Models and Arthritis, Experimental.
Cross Reference
Introduction
To understand associated biological information of DHA, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with DHA?
DHA is suspected in Cardiovascular Diseases, Obesity, Ischemia, Hypertensive disease, Coronary Arteriosclerosis, Cerebrovascular accident and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with DHA
PubChem Associated disorders and diseases
What pathways are associated with DHA
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with DHA?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with DHA?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with DHA?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with DHA?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with DHA?
Mouse Model
Mouse Model are used in the study 'Homeostatic regulation of photoreceptor cell integrity: significance of the potent mediator neuroprotectin D1 biosynthesized from docosahexaenoic acid: the Proctor Lecture.' (Bazan NG, 2007), Mouse Model are used in the study 'Omega-3 fatty acids EPA and DHA: health benefits throughout life.' (Swanson D et al., 2012), Mouse Model are used in the study 'Docosahexaenoic acid attenuates hepatic inflammation, oxidative stress, and fibrosis without decreasing hepatosteatosis in a Ldlr(-/-) mouse model of western diet-induced nonalcoholic steatohepatitis.' (Depner CM et al., 2013) and Mouse Model are used in the study 'Wax esters from the marine copepod Calanus finmarchicus reduce diet-induced obesity and obesity-related metabolic disorders in mice.' (Höper AC et al., 2014).
Transgenic Model
Transgenic Model are used in the study 'Loss of MAP function leads to hippocampal synapse loss and deficits in the Morris Water Maze with aging.' (Ma QL et al., 2014).
Animal Disease Models
Animal Disease Models are used in the study 'Fish oil increases muscle protein mass and modulates Akt/FOXO, TLR4, and NOD signaling in weanling piglets after lipopolysaccharide challenge.' (Liu Y et al., 2013).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with DHA
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Westberg G and Tarkowski A | Effect of MaxEPA in patients with SLE. A double-blind, crossover study. | 1990 | Scand. J. Rheumatol. | pmid:2186476 |
| Thusgaard M et al. | Effect of fish oil (n-3 polyunsaturated fatty acids) on plasma lipids, lipoproteins and inflammatory markers in HIV-infected patients treated with antiretroviral therapy: a randomized, double-blind, placebo-controlled study. | 2009 | Scand. J. Infect. Dis. | pmid:19685375 |
| Khalfoun B et al. | Docosahexaenoic and eicosapentaenoic acids inhibit human lymphoproliferative responses in vitro but not the expression of T cell surface activation markers. | 1996 | Scand. J. Immunol. | pmid:8602457 |
| Solakivi T et al. | Serum fatty acid profile in subjects with irritable bowel syndrome. | 2011 | Scand. J. Gastroenterol. | pmid:21073373 |
| Andersson L et al. | Hydrolysis of phosphatidylethanolamine by human pancreatic phospholipase A2. Effect of bile salts. | 1994 | Scand. J. Gastroenterol. | pmid:8171289 |
| Hexeberg S et al. | Docosahexaenoic acid induces lipid accumulation in myocardial cells of rats. | 1994 | Scand. J. Clin. Lab. Invest. | pmid:7709170 |
| Hagve TA et al. | Membrane fluidity and fatty acid metabolism in kidney cells from rats fed purified eicosapentaenoic acid or purified docosahexaenoic acid. | 1998 | Scand. J. Clin. Lab. Invest. | pmid:9670342 |
| Eritsland J et al. | Long-term effects of n-3 fatty acids on serum lipids and glycaemic control. | 1994 | Scand. J. Clin. Lab. Invest. | pmid:7939369 |
| Foulon T et al. | Effects of fish oil fatty acids on plasma lipids and lipoproteins and oxidant-antioxidant imbalance in healthy subjects. | 1999 | Scand. J. Clin. Lab. Invest. | pmid:10463462 |
| Schjøtt J et al. | Infusion of EPA and DHA lipid emulsions: effects on heart lipids and tolerance to ischaemia-reperfusion in the isolated rat heart. | 1993 | Scand. J. Clin. Lab. Invest. | pmid:8140399 |
| Hagve TA et al. | The decrease in osmotic fragility of erythrocytes during supplementation with n-3 fatty acids is a transient phenomenon. | 1991 | Scand. J. Clin. Lab. Invest. | pmid:1835122 |
| Carvajal O and Angulo O | Effect of n-3 polyunsaturated fatty acids on the lipidic profile of healthy Mexican volunteers. | 1997 May-Jun | Salud Publica Mex | pmid:9304226 |
| Chetty N et al. | Fatty acid composition of some South African fresh-water fish. | 1989 | S. Afr. Med. J. | pmid:2552593 |
| Buznikov GA et al. | [Cholinergic regulation of the sea urchin embryonic and larval development]. | 2001 | Ross Fiziol Zh Im I M Sechenova | pmid:11822358 |
| Cardoso C et al. | Methylmercury risks and EPA + DHA benefits associated with seafood consumption in Europe. | 2010 | Risk Anal. | pmid:20604879 |
| Yazawa K | [Importance of "health foods", EPA and DHA, for preventive medicine]. | 2004 | Rinsho Byori | pmid:15137325 |
| Torres AG and Trugo NM | Evidence of inadequate docosahexaenoic acid status in Brazilian pregnant and lactating women. | 2009 | Rev Saude Publica | pmid:19287877 |
| Wright AK et al. | Slowly progressive dopamine cell loss--a model on which to test neuroprotective strategies for Parkinson's disease? | 2009 | Rev Neurosci | pmid:19774787 |
| Gutiérrez-Mata AP et al. | [Neurological, neuropsychological, and ophthalmological evolution after one year of docosahexaenoic acid supplementation in phenylketonuric patients]. | 2012 | Rev Neurol | pmid:22829083 |
| MartÃnez M et al. | [Treatment of generalized peroxisomal disorders with docosahexaenoic acid ethyl ether]. | 1999 | Rev Neurol | pmid:10778491 |