DHA

Dha is a lipid of Fatty Acyls (FA) class. Dha is associated with abnormalities such as Atherosclerosis, Consumption-archaic term for TB, Chronic disease, Cardiovascular Diseases and Diabetes Mellitus, Non-Insulin-Dependent. The involved functions are known as Inflammation, Oxidation, fatty acid oxidation, Fatty Acid Metabolism and Lipid Metabolism. Dha often locates in Hepatic, Protoplasm, Mucous Membrane, Epithelium and outer membrane. The associated genes with DHA are IMPACT gene, FATE1 gene, GAPDH gene, THOC4 gene and SLC33A1 gene. The related lipids are stearidonic acid, Fatty Acids, Total cholesterol, Lipopolysaccharides and Dietary Fatty Acid. The related experimental models are Mouse Model, Transgenic Model, Animal Disease Models and Arthritis, Experimental.

Cross Reference

Introduction

To understand associated biological information of DHA, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with DHA?

DHA is suspected in Cardiovascular Diseases, Obesity, Ischemia, Hypertensive disease, Coronary Arteriosclerosis, Cerebrovascular accident and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with DHA

MeSH term MeSH ID Detail
Hydroa Vacciniforme D006837 1 associated lipids
Hypercholesterolemia D006937 91 associated lipids
Hyperlipoproteinemia Type II D006938 22 associated lipids
Hyperlipidemias D006949 73 associated lipids
Hyperlipidemia, Familial Combined D006950 9 associated lipids
Hyperlipoproteinemias D006951 15 associated lipids
Hyperlipoproteinemia Type IV D006953 6 associated lipids
Hypersensitivity D006967 22 associated lipids
Hypersensitivity, Delayed D006968 43 associated lipids
Hypertension D006973 115 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with DHA

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with DHA?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with DHA?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with DHA?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with DHA?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with DHA?

Mouse Model

Mouse Model are used in the study 'Homeostatic regulation of photoreceptor cell integrity: significance of the potent mediator neuroprotectin D1 biosynthesized from docosahexaenoic acid: the Proctor Lecture.' (Bazan NG, 2007), Mouse Model are used in the study 'Omega-3 fatty acids EPA and DHA: health benefits throughout life.' (Swanson D et al., 2012), Mouse Model are used in the study 'Docosahexaenoic acid attenuates hepatic inflammation, oxidative stress, and fibrosis without decreasing hepatosteatosis in a Ldlr(-/-) mouse model of western diet-induced nonalcoholic steatohepatitis.' (Depner CM et al., 2013) and Mouse Model are used in the study 'Wax esters from the marine copepod Calanus finmarchicus reduce diet-induced obesity and obesity-related metabolic disorders in mice.' (Höper AC et al., 2014).

Transgenic Model

Transgenic Model are used in the study 'Loss of MAP function leads to hippocampal synapse loss and deficits in the Morris Water Maze with aging.' (Ma QL et al., 2014).

Animal Disease Models

Animal Disease Models are used in the study 'Fish oil increases muscle protein mass and modulates Akt/FOXO, TLR4, and NOD signaling in weanling piglets after lipopolysaccharide challenge.' (Liu Y et al., 2013).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with DHA

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Per page 10 20 50 100 | Total 7336
Authors Title Published Journal PubMed Link
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Blachier F et al. Arachidonic acid metabolism and casein secretion in lactating rabbit mammary epithelial cells: effects of inhibitors of prostaglandins and leukotrienes synthesis. 1988 Prostaglandins pmid:2834771
Kim HY and Salem N Preparation and the structural determination of hydroperoxy derivatives of docosahexaenoic acid and other polyunsaturates by thermospray LC/MS. 1989 Prostaglandins pmid:2541468
Mai J et al. A new prostaglandin, C22-PGF4 alpha, synthesized from docosahexaenoic acid (C22:6n3) by trout gill. 1981 Prostaglandins pmid:6280241
Kim HY et al. Stereochemical analysis of hydroxylated docosahexaenoates produced by human platelets and rat brain homogenate. 1990 Prostaglandins pmid:2147773
Kim HY et al. Formation of 15-lipoxygenase product from docosahexaenoic acid (22:6w3) by human platelets. 1990 Prostaglandins pmid:2147774
Fischer S et al. Dietary docosahexaenoic acid is retroconverted in man to eicosapentaenoic acid, which can be quickly transformed to prostaglandin I3. 1987 Prostaglandins pmid:2829279
Hishinuma T et al. Microdetermination of the thromboxane B3 gas chromatography-selected-ion monitoring using [18O]thromboxane B3 as an internal standard. 1997 Prostaglandins pmid:9261859
Claeys M et al. Diacylglycerols interfere in normal phase HPLC analysis of lipoxygenase products of docosahexaenoic or arachidonic acids. 1986 Prostaglandins pmid:2951768
van de Lagemaat M et al. Post term dietary-induced changes in DHA and AA status relate to gains in weight, length, and head circumference in preterm infants. 2011 Prostaglandins Leukot. Essent. Fatty Acids pmid:21995887
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Kruger MC and Schollum LM Is docosahexaenoic acid more effective than eicosapentaenoic acid for increasing calcium bioavailability? 2005 Prostaglandins Leukot. Essent. Fatty Acids pmid:16154334
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Nyuar KB et al. Regular consumption of Nile river fish could ameliorate the low milk DHA of Southern Sudanese women living in Khartoum City area. 2013 Prostaglandins Leukot. Essent. Fatty Acids pmid:23706881
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Kearns SD and Haag M The effect of omega-3 fatty acids on Ca-ATPase in rat cerebral cortex. 2002 Prostaglandins Leukot. Essent. Fatty Acids pmid:12445489
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Block RC et al. The effects of aspirin on platelet function and lysophosphatidic acids depend on plasma concentrations of EPA and DHA. 2015 Prostaglandins Leukot. Essent. Fatty Acids pmid:25555354
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Makrides M DHA supplementation during the perinatal period and neurodevelopment: Do some babies benefit more than others? 2013 Prostaglandins Leukot. Essent. Fatty Acids pmid:22698951
Van Biervliet S et al. Oral DHA supplementation in DeltaF508 homozygous cystic fibrosis patients. 2008 Prostaglandins Leukot. Essent. Fatty Acids pmid:18276127
Matsumoto K et al. Inhibitory effect of docosahexaenoic acid-containing phospholipids on 5-lipoxygenase in rat basophilic leukemia cells. 1993 Prostaglandins Leukot. Essent. Fatty Acids pmid:8302921
Otto SJ et al. Increased risk of postpartum depressive symptoms is associated with slower normalization after pregnancy of the functional docosahexaenoic acid status. 2003 Prostaglandins Leukot. Essent. Fatty Acids pmid:12907133
Brouwer IA Omega-3 PUFA: good or bad for prostate cancer? 2008 Sep-Nov Prostaglandins Leukot. Essent. Fatty Acids pmid:18951003