| MeSH term | MeSH ID | Detail |
|---|---|---|
| Pulmonary Valve Stenosis | D011666 | 1 associated lipids |
| Cerebrovascular Trauma | D020214 | 1 associated lipids |
| Histiocytoma, Malignant Fibrous | D051677 | 1 associated lipids |
| Hydroa Vacciniforme | D006837 | 1 associated lipids |
| Communication Disorders | D003147 | 1 associated lipids |
| Trophoblastic Tumor, Placental Site | D018245 | 1 associated lipids |
| Geographic Atrophy | D057092 | 1 associated lipids |
| Phenylketonuria, Maternal | D017042 | 1 associated lipids |
| Lordosis | D008141 | 1 associated lipids |
| Refsum Disease, Infantile | D052919 | 1 associated lipids |
DHA
Dha is a lipid of Fatty Acyls (FA) class. Dha is associated with abnormalities such as Atherosclerosis, Consumption-archaic term for TB, Chronic disease, Cardiovascular Diseases and Diabetes Mellitus, Non-Insulin-Dependent. The involved functions are known as Inflammation, Oxidation, fatty acid oxidation, Fatty Acid Metabolism and Lipid Metabolism. Dha often locates in Hepatic, Protoplasm, Mucous Membrane, Epithelium and outer membrane. The associated genes with DHA are IMPACT gene, FATE1 gene, GAPDH gene, THOC4 gene and SLC33A1 gene. The related lipids are stearidonic acid, Fatty Acids, Total cholesterol, Lipopolysaccharides and Dietary Fatty Acid. The related experimental models are Mouse Model, Transgenic Model, Animal Disease Models and Arthritis, Experimental.
Cross Reference
Introduction
To understand associated biological information of DHA, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with DHA?
DHA is suspected in Cardiovascular Diseases, Obesity, Ischemia, Hypertensive disease, Coronary Arteriosclerosis, Cerebrovascular accident and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with DHA
PubChem Associated disorders and diseases
What pathways are associated with DHA
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with DHA?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with DHA?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with DHA?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with DHA?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with DHA?
Mouse Model
Mouse Model are used in the study 'Homeostatic regulation of photoreceptor cell integrity: significance of the potent mediator neuroprotectin D1 biosynthesized from docosahexaenoic acid: the Proctor Lecture.' (Bazan NG, 2007), Mouse Model are used in the study 'Omega-3 fatty acids EPA and DHA: health benefits throughout life.' (Swanson D et al., 2012), Mouse Model are used in the study 'Docosahexaenoic acid attenuates hepatic inflammation, oxidative stress, and fibrosis without decreasing hepatosteatosis in a Ldlr(-/-) mouse model of western diet-induced nonalcoholic steatohepatitis.' (Depner CM et al., 2013) and Mouse Model are used in the study 'Wax esters from the marine copepod Calanus finmarchicus reduce diet-induced obesity and obesity-related metabolic disorders in mice.' (Höper AC et al., 2014).
Transgenic Model
Transgenic Model are used in the study 'Loss of MAP function leads to hippocampal synapse loss and deficits in the Morris Water Maze with aging.' (Ma QL et al., 2014).
Animal Disease Models
Animal Disease Models are used in the study 'Fish oil increases muscle protein mass and modulates Akt/FOXO, TLR4, and NOD signaling in weanling piglets after lipopolysaccharide challenge.' (Liu Y et al., 2013).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with DHA
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Carlson SE | Lessons learned from randomizing infants to marine oil-supplemented formulas in nutrition trials. | 1994 | J. Pediatr. | pmid:7965451 |
| Saito M and Nakatsugawa K | Increased susceptibility of liver to lipid peroxidation after ingestion of a high fish oil diet. | 1994 | Int J Vitam Nutr Res | pmid:7960494 |
| Anti M et al. | Effects of different doses of fish oil on rectal cell proliferation in patients with sporadic colonic adenomas. | 1994 | Gastroenterology | pmid:7958682 |
| Eritsland J et al. | Long-term effects of n-3 fatty acids on serum lipids and glycaemic control. | 1994 | Scand. J. Clin. Lab. Invest. | pmid:7939369 |
| Kang JX and Leaf A | Effects of long-chain polyunsaturated fatty acids on the contraction of neonatal rat cardiac myocytes. | 1994 | Proc. Natl. Acad. Sci. U.S.A. | pmid:7937911 |
| Karanian JW et al. | Inhibitory effects of n-6 and n-3 hydroxy fatty acids on thromboxane (U46619)-induced smooth muscle contraction. | 1994 | J. Pharmacol. Exp. Ther. | pmid:7932158 |
| Ikeda I et al. | alpha-Linolenic, eicosapentaenoic and docosahexaenoic acids affect lipid metabolism differently in rats. | 1994 | J. Nutr. | pmid:7931698 |
| Arm JP et al. | Leukotrienes, fish-oil, and asthma. | 1994 May-Jun | Allergy Proc | pmid:7926711 |
| del Carmen Boyano-Adánez M et al. | Protein kinase C-mediated phospholipase D activity is increased by linolenic acid supplementation in NG 108-15 cells. | 1994 | Biochim. Biophys. Acta | pmid:7918608 |
| Tremoli E et al. | n-3 fatty acid ethyl ester administration to healthy subjects and to hypertriglyceridemic patients reduces tissue factor activity in adherent monocytes. | 1994 | Arterioscler. Thromb. | pmid:7918310 |
| Winters BL et al. | Linolenic acid provides a source of docosahexaenoic acid for artificially reared rat pups. | 1994 | J. Nutr. | pmid:7916377 |
| Makrides M et al. | Fatty acid composition of brain, retina, and erythrocytes in breast- and formula-fed infants. | 1994 | Am. J. Clin. Nutr. | pmid:7913291 |
| Anderson GJ and Connor WE | Accretion of n-3 fatty acids in the brain and retina of chicks fed a low-linolenic acid diet supplemented with docosahexaenoic acid. | 1994 | Am. J. Clin. Nutr. | pmid:7911000 |
| Green P and Yavin E | Elongation, desaturation, and esterification of essential fatty acids by fetal rat brain in vivo. | 1993 | J. Lipid Res. | pmid:7905509 |
| Ghebremeskel K et al. | Fatty acid composition of plasma and red cell phospholipids of preterm babies fed on breast milk and formulae. | 1995 | Eur. J. Pediatr. | pmid:7895755 |
| Karikó K et al. | Stimulatory effect of unsaturated fatty acids on the level of plasminogen activator inhibitor-1 mRNA in cultured human endothelial cells. | 1995 | FEBS Lett. | pmid:7890029 |
| Gibney MJ and Daly E | The incorporation of n-3 polyunsaturated fatty acids into plasma lipid and lipoprotein fractions in the postprandial phase in healthy volunteers. | 1994 | Eur J Clin Nutr | pmid:7889895 |
| Purasiri P et al. | Modulation of cytokine production in vivo by dietary essential fatty acids in patients with colorectal cancer. | 1994 | Clin. Sci. | pmid:7874864 |
| Santos MJ et al. | Influence of dietary supplementation with fish on plasma fatty acid composition in coronary heart disease patients. | 1995 | Ann. Nutr. Metab. | pmid:7872656 |
| Martinez M | Polyunsaturated fatty acids in the developing human brain, red cells and plasma: influence of nutrition and peroxisomal disease. | 1994 | World Rev Nutr Diet | pmid:7871835 |
| von Houwelingen AC and Hornstra G | Trans fatty acids in early human development. | 1994 | World Rev Nutr Diet | pmid:7871822 |
| Anderson RE et al. | The accretion of docosahexaenoic acid in the retina. | 1994 | World Rev Nutr Diet | pmid:7871813 |
| Bazan NG et al. | Docosahexaenoic acid supply to the retina and its conservation in photoreceptor cells by active retinal pigment epithelium-mediated recycling. | 1994 | World Rev Nutr Diet | pmid:7871812 |
| Chen LY et al. | Reduction in human neutrophil superoxide anion generation by n-3 polyunsaturated fatty acids: role of cyclooxygenase products and endothelium-derived relaxing factor. | 1994 | Thromb. Res. | pmid:7871491 |
| Poling JS et al. | Time- and voltage-dependent block of delayed rectifier potassium channels by docosahexaenoic acid. | 1995 | Mol. Pharmacol. | pmid:7870048 |
| Tessier C et al. | Docosahexaenoic acid is a potent inhibitor of rat uterine stromal cell proliferation. | 1995 | Biochem. Biophys. Res. Commun. | pmid:7864887 |
| Al MD et al. | The relationship between the essential fatty acid status of mother and child and the occurrence of pregnancy-induced hypertension. Intermediate results of a prospective longitudinal study. | 1994 | World Rev Nutr Diet | pmid:7856218 |
| Alexander-North LS et al. | Polyunsaturated fatty acids increase lipid radical formation induced by oxidant stress in endothelial cells. | 1994 | J. Lipid Res. | pmid:7852854 |
| Lokesh BR and Kinsella JE | Effects of n-3 polyunsaturated fatty acids on the reacylation of arachidonic acid in peritoneal macrophages. | 1994 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:7846090 |
| Vaidyanathan VV et al. | Regulation of diacylglycerol kinase in rat brain membranes by docosahexaenoic acid. | 1994 | Neurosci. Lett. | pmid:7845615 |
| Yamashiro Y et al. | Docosahexaenoic acid status of patients with extrahepatic biliary atresia. | 1994 | J. Pediatr. Surg. | pmid:7844720 |
| Terasawa F et al. | Effects of dietary casein and soy-protein on metabolic conversion of eicosapentaenoic acid to docosahexaenoic acid in the liver of rat. | 1994 | J. Nutr. Sci. Vitaminol. | pmid:7844642 |
| Popp-Snijders C and Blonk MC | Omega-3 fatty acids in adipose tissue of obese patients with non-insulin-dependent diabetes mellitus reflect long-term dietary intake of eicosapentaenoic and docosahexaenoic acid. | 1995 | Am. J. Clin. Nutr. | pmid:7840075 |
| Kurlandsky LE et al. | The absorption and effect of dietary supplementation with omega-3 fatty acids on serum leukotriene B4 in patients with cystic fibrosis. | 1994 | Pediatr. Pulmonol. | pmid:7838619 |
| Bazan NG and Rodriguez de Turco EB | Review: pharmacological manipulation of docosahexaenoic-phospholipid biosynthesis in photoreceptor cells: implications in retinal degeneration. | 1994 | J Ocul Pharmacol | pmid:7836869 |
| Gazzah N et al. | Decrease of brain phospholipid synthesis in free-moving n-3 fatty acid deficient rats. | 1995 | J. Neurochem. | pmid:7830085 |
| Delton I et al. | Distribution and metabolism of arachidonic and docosahexaenoic acids in rat pineal cells. Effect of norepinephrine. | 1995 | Biochim. Biophys. Acta | pmid:7827119 |
| Christensen MS et al. | Intestinal absorption and lymphatic transport of eicosapentaenoic (EPA), docosahexaenoic (DHA), and decanoic acids: dependence on intramolecular triacylglycerol structure. | 1995 | Am. J. Clin. Nutr. | pmid:7825539 |
| Das UN | Beneficial effect of eicosapentaenoic and docosahexaenoic acids in the management of systemic lupus erythematosus and its relationship to the cytokine network. | 1994 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:7824535 |
| Gazzah N et al. | Evidence for brain docosahexaenoate recycling in the free-moving adult rat: implications for measurement of phospholipid synthesis. | 1994 | Neurosci. Lett. | pmid:7824158 |
| Petroni A et al. | Inhibition by n-3 fatty acids of arachidonic acid metabolism in a primary culture of astroglial cells. | 1994 | Neurochem. Res. | pmid:7824073 |
| Khair-el-Din TA et al. | Docosahexaenoic acid, a major constituent of fetal serum and fish oil diets, inhibits IFN gamma-induced Ia-expression by murine macrophages in vitro. | 1995 | J. Immunol. | pmid:7822798 |
| Roche H and Gibney MJ | The effect of consumption of fish oil-enriched spreadable fats on platelet phospholipid fatty acid composition in human volunteers. | 1994 | Int J Vitam Nutr Res | pmid:7814240 |
| Kim HY et al. | Liquid chromatography/mass spectrometry of phospholipids using electrospray ionization. | 1994 | Anal. Chem. | pmid:7810900 |
| Mallampalli RK et al. | Regulation of CTP:choline-phosphate cytidylyltransferase by polyunsaturated n-3 fatty acids. | 1994 | Am. J. Physiol. | pmid:7810669 |
| Kinoshita K et al. | Inhibitory effects of purified eicosapentaenoic acid and docosahexaenoic acid on growth and metastasis of murine transplantable mammary tumor. | 1994 May-Jun | In Vivo | pmid:7803721 |
| Zerouga M et al. | Comparison of phosphatidylcholines containing one or two docosahexaenoic acyl chains on properties of phospholipid monolayers and bilayers. | 1995 | Biochim. Biophys. Acta | pmid:7794965 |
| Jenski LJ et al. | Docosahexaenoic acid-induced alteration of Thy-1 and CD8 expression on murine splenocytes. | 1995 | Biochim. Biophys. Acta | pmid:7794954 |
| Burdge GC and Postle AD | Effect of maternal ethanol consumption during pregnancy on the phospholipid molecular species composition of fetal guinea-pig brain, liver and plasma. | 1995 | Biochim. Biophys. Acta | pmid:7786898 |
| Shimizu S et al. | omega-Hydroxylation of docosahexaenoic acid or arachidonic acid in human colonic well differentiated adenocarcinoma homogenate. | 1995 | Biochim. Biophys. Acta | pmid:7786890 |