| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hydroa Vacciniforme | D006837 | 1 associated lipids |
| Communication Disorders | D003147 | 1 associated lipids |
| Trophoblastic Tumor, Placental Site | D018245 | 1 associated lipids |
| Geographic Atrophy | D057092 | 1 associated lipids |
| Phenylketonuria, Maternal | D017042 | 1 associated lipids |
| Lordosis | D008141 | 1 associated lipids |
| Refsum Disease, Infantile | D052919 | 1 associated lipids |
| Pulmonary Valve Stenosis | D011666 | 1 associated lipids |
| Cerebrovascular Trauma | D020214 | 1 associated lipids |
| Histiocytoma, Malignant Fibrous | D051677 | 1 associated lipids |
DHA
Dha is a lipid of Fatty Acyls (FA) class. Dha is associated with abnormalities such as Atherosclerosis, Consumption-archaic term for TB, Chronic disease, Cardiovascular Diseases and Diabetes Mellitus, Non-Insulin-Dependent. The involved functions are known as Inflammation, Oxidation, fatty acid oxidation, Fatty Acid Metabolism and Lipid Metabolism. Dha often locates in Hepatic, Protoplasm, Mucous Membrane, Epithelium and outer membrane. The associated genes with DHA are IMPACT gene, FATE1 gene, GAPDH gene, THOC4 gene and SLC33A1 gene. The related lipids are stearidonic acid, Fatty Acids, Total cholesterol, Lipopolysaccharides and Dietary Fatty Acid. The related experimental models are Mouse Model, Transgenic Model, Animal Disease Models and Arthritis, Experimental.
Cross Reference
Introduction
To understand associated biological information of DHA, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with DHA?
DHA is suspected in Cardiovascular Diseases, Obesity, Ischemia, Hypertensive disease, Coronary Arteriosclerosis, Cerebrovascular accident and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with DHA
PubChem Associated disorders and diseases
What pathways are associated with DHA
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with DHA?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with DHA?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with DHA?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with DHA?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with DHA?
Mouse Model
Mouse Model are used in the study 'Homeostatic regulation of photoreceptor cell integrity: significance of the potent mediator neuroprotectin D1 biosynthesized from docosahexaenoic acid: the Proctor Lecture.' (Bazan NG, 2007), Mouse Model are used in the study 'Omega-3 fatty acids EPA and DHA: health benefits throughout life.' (Swanson D et al., 2012), Mouse Model are used in the study 'Docosahexaenoic acid attenuates hepatic inflammation, oxidative stress, and fibrosis without decreasing hepatosteatosis in a Ldlr(-/-) mouse model of western diet-induced nonalcoholic steatohepatitis.' (Depner CM et al., 2013) and Mouse Model are used in the study 'Wax esters from the marine copepod Calanus finmarchicus reduce diet-induced obesity and obesity-related metabolic disorders in mice.' (Höper AC et al., 2014).
Transgenic Model
Transgenic Model are used in the study 'Loss of MAP function leads to hippocampal synapse loss and deficits in the Morris Water Maze with aging.' (Ma QL et al., 2014).
Animal Disease Models
Animal Disease Models are used in the study 'Fish oil increases muscle protein mass and modulates Akt/FOXO, TLR4, and NOD signaling in weanling piglets after lipopolysaccharide challenge.' (Liu Y et al., 2013).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with DHA
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Reardon HT et al. | Dietary long-chain polyunsaturated fatty acids upregulate expression of FADS3 transcripts. | 2013 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:22398025 |
| Lee HJ et al. | Resolvin D1 inhibits TGF-β1-induced epithelial mesenchymal transition of A549 lung cancer cells via lipoxin A4 receptor/formyl peptide receptor 2 and GPR32. | 2013 | Int. J. Biochem. Cell Biol. | pmid:24120851 |
| Offman E et al. | Steady-state bioavailability of prescription omega-3 on a low-fat diet is significantly improved with a free fatty acid formulation compared with an ethyl ester formulation: the ECLIPSE II study. | 2013 | Vasc Health Risk Manag | pmid:24124374 |
| Galvao TF et al. | Marine n3 polyunsaturated fatty acids enhance resistance to mitochondrial permeability transition in heart failure but do not improve survival. | 2013 | Am. J. Physiol. Heart Circ. Physiol. | pmid:23103493 |
| Tsuboi H et al. | Associations of depressive symptoms with serum proportions of palmitic and arachidonic acids, and α-tocopherol effects among male population--a preliminary study. | 2013 | Clin Nutr | pmid:22901744 |
| Lindberg M et al. | Long-term tracking of plasma phospholipid fatty acid concentrations and their correlation with the dietary intake of marine foods in newly diagnosed diabetic patients: results from a follow-up of the HUNT Study, Norway. | 2013 | Br. J. Nutr. | pmid:22846205 |
| Hu Y et al. | 15-Lipoxygenase-1-mediated metabolism of docosahexaenoic acid is required for syndecan-1 signaling and apoptosis in prostate cancer cells. | 2013 | Carcinogenesis | pmid:23066085 |
| Tang Y et al. | Proresolution therapy for the treatment of delayed healing of diabetic wounds. | 2013 | Diabetes | pmid:23043160 |
| Gillingham LG et al. | Dietary oils and FADS1-FADS2 genetic variants modulate [13C]α-linolenic acid metabolism and plasma fatty acid composition. | 2013 | Am. J. Clin. Nutr. | pmid:23221573 |
| Chien KL et al. | A Taiwanese food frequency questionnaire correlates with plasma docosahexaenoic acid but not with plasma eicosapentaenoic acid levels: questionnaires and plasma biomarkers. | 2013 | BMC Med Res Methodol | pmid:23414574 |
| Maskrey BH et al. | Emerging importance of omega-3 fatty acids in the innate immune response: molecular mechanisms and lipidomic strategies for their analysis. | 2013 | Mol Nutr Food Res | pmid:23417926 |
| Hjorth E et al. | Omega-3 fatty acids enhance phagocytosis of Alzheimer's disease-related amyloid-β42 by human microglia and decrease inflammatory markers. | 2013 | J. Alzheimers Dis. | pmid:23481688 |
| Lee MS et al. | Effects of eicosapentaenoic acid and docosahexaenoic acid on uncoupling protein 3 gene expression in C(2)C(12) muscle cells. | 2013 | Nutrients | pmid:23698161 |
| Yamaguchi M et al. | Consumption of seafood, serum liver enzymes, and blood levels of PFOS and PFOA in the Japanese population. | 2013 | J Occup Health | pmid:23574777 |
| Correia M et al. | Crosstalk between Helicobacter pylori and gastric epithelial cells is impaired by docosahexaenoic acid. | 2013 | PLoS ONE | pmid:23577140 |
| Weise C et al. | Dietary polyunsaturated fatty acids and non-digestible oligosaccharides reduce dermatitis in mice. | 2013 | Pediatr Allergy Immunol | pmid:23577592 |
| Araújo JR et al. | Gestational diabetes mellitus decreases placental uptake of long-chain polyunsaturated fatty acids: involvement of long-chain acyl-CoA synthetase. | 2013 | J. Nutr. Biochem. | pmid:23790250 |
| Russell KL et al. | Low brain DHA content worsens sensorimotor outcomes after TBI and decreases TBI-induced Timp1 expression in juvenile rats. | 2013 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:23796971 |
| Xue Z et al. | Production of omega-3 eicosapentaenoic acid by metabolic engineering of Yarrowia lipolytica. | 2013 | Nat. Biotechnol. | pmid:23873085 |
| Emmett R et al. | Expanding awareness of docosahexaenoic acid during pregnancy. | 2013 | Nutrients | pmid:23549329 |
| Haller MJ et al. | Autologous umbilical cord blood infusion followed by oral docosahexaenoic acid and vitamin D supplementation for C-peptide preservation in children with Type 1 diabetes. | 2013 | Biol. Blood Marrow Transplant. | pmid:23611977 |
| Chen J et al. | Docosahexaenoic acid (DHA) ameliorates paraquat-induced pulmonary fibrosis in rats possibly through up-regulation of Smad 7 and SnoN. | 2013 | Food Chem. Toxicol. | pmid:23590892 |
| Dalli J et al. | Novel n-3 immunoresolvents: structures and actions. | 2013 | Sci Rep | pmid:23736886 |
| Finlin BS et al. | Regulation of thrombospondin-1 expression in alternatively activated macrophages and adipocytes: role of cellular cross talk and omega-3 fatty acids. | 2013 | J. Nutr. Biochem. | pmid:23528972 |
| Rashid MA et al. | N-Docosahexaenoylethanolamine is a potent neurogenic factor for neural stem cell differentiation. | 2013 | J. Neurochem. | pmid:23570577 |
| Shiraishi M et al. | Estimation of eicosapentaenoic acid and docosahexaenoic acid intakes in pregnant Japanese women without nausea by using a self-administered diet history questionnaire. | 2013 | Nutr Res | pmid:23746563 |
| Vaezi R et al. | Identification and functional characterization of genes encoding omega-3 polyunsaturated fatty acid biosynthetic activities from unicellular microalgae. | 2013 | Mar Drugs | pmid:24351909 |
| Thomas J et al. | Dietary supplementation with resveratrol and/or docosahexaenoic acid alters hippocampal gene expression in adult C57Bl/6 mice. | 2013 | J. Nutr. Biochem. | pmid:23746933 |
| Jung SB et al. | Docosahexaenoic acid improves vascular function via up-regulation of SIRT1 expression in endothelial cells. | 2013 | Biochem. Biophys. Res. Commun. | pmid:23806688 |
| Decsi T and Boehm G | trans Isomeric fatty acids are inversely related to the availability of long-chain PUFAs in the perinatal period. | 2013 | Am. J. Clin. Nutr. | pmid:23824720 |
| Lundström SL et al. | Lipid mediator serum profiles in asthmatics significantly shift following dietary supplementation with omega-3 fatty acids. | 2013 | Mol Nutr Food Res | pmid:23824870 |
| Kitson AP et al. | Treatment of ovariectomized rats with 17β-estradiol increases hepatic delta-6 desaturase enzyme expression and docosahexaenoic acid levels in hepatic and plasma phospholipids. | 2013 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:23764042 |
| Taha AY et al. | A minimum of 3 months of dietary fish oil supplementation is required to raise amygdaloid afterdischarge seizure thresholds in rats--implications for treating complex partial seizures. | 2013 | Epilepsy Behav | pmid:23376336 |
| Ramkumar HL et al. | Nutrient supplementation with n3 polyunsaturated fatty acids, lutein, and zeaxanthin decrease A2E accumulation and VEGF expression in the retinas of Ccl2/Cx3cr1-deficient mice on Crb1rd8 background. | 2013 | J. Nutr. | pmid:23677863 |
| Nobre ME et al. | Eicosapentaenoic acid and docosahexaenoic acid exert anti-inflammatory and antinociceptive effects in rodents at low doses. | 2013 | Nutr Res | pmid:23684444 |
| Xu ZZ et al. | Neuroprotectin/protectin D1 protects against neuropathic pain in mice after nerve trauma. | 2013 | Ann. Neurol. | pmid:23686636 |
| Begum G et al. | ER stress and effects of DHA as an ER stress inhibitor. | 2013 | Transl Stroke Res | pmid:24323417 |
| Bjorgvinsdottir L et al. | Do high levels of n-3 polyunsaturated fatty acids in cell membranes increase the risk of postoperative atrial fibrillation? | 2013 | Cardiology | pmid:23948862 |
| Lee AL and Park Y | The association between n-3 polyunsaturated fatty acid levels in erythrocytes and the risk of rheumatoid arthritis in Korean women. | 2013 | Ann. Nutr. Metab. | pmid:23949659 |
| Metherel AH et al. | EPA and DHA levels in whole blood decrease more rapidly when stored at -20 °C as compared with room temperature, 4 and -75 °C. | 2013 | Lipids | pmid:23949919 |
| Chung ML et al. | Profiling of oxidized lipid products of marine fish under acute oxidative stress. | 2013 | Food Chem. Toxicol. | pmid:23220612 |
| van der Merwe LF et al. | Long-chain PUFA supplementation in rural African infants: a randomized controlled trial of effects on gut integrity, growth, and cognitive development. | 2013 | Am. J. Clin. Nutr. | pmid:23221579 |
| Betancor MB et al. | Physiological pathways involved in nutritional muscle dystrophy and healing in European sea bass (Dicentrarchus labrax) larvae. | 2013 | Comp. Biochem. Physiol., Part A Mol. Integr. Physiol. | pmid:23202658 |
| Zeilmaker MJ et al. | Fish consumption during child bearing age: a quantitative risk-benefit analysis on neurodevelopment. | 2013 | Food Chem. Toxicol. | pmid:22079313 |
| Wu BT et al. | Low fish intake is associated with low blood concentrations of vitamin D, choline and n-3 DHA in pregnant women. | 2013 | Br. J. Nutr. | pmid:22691303 |
| Marcon R et al. | Maresin 1, a proresolving lipid mediator derived from omega-3 polyunsaturated fatty acids, exerts protective actions in murine models of colitis. | 2013 | J. Immunol. | pmid:24038091 |
| Fontes-Villalba M et al. | African hominin stable isotopic data do not necessarily indicate grass consumption. | 2013 | Proc. Natl. Acad. Sci. U.S.A. | pmid:24062471 |
| Jaudszus A et al. | Evaluation of suppressive and pro-resolving effects of EPA and DHA in human primary monocytes and T-helper cells. | 2013 | J. Lipid Res. | pmid:23349208 |
| Neuhofer A et al. | Impaired local production of proresolving lipid mediators in obesity and 17-HDHA as a potential treatment for obesity-associated inflammation. | 2013 | Diabetes | pmid:23349501 |
| Sofi F et al. | The atherosclerotic risk profile is affected differently by fish flesh with a similar EPA and DHA content but different n-6/n-3 ratio. | 2013 | Asia Pac J Clin Nutr | pmid:23353608 |