| MeSH term | MeSH ID | Detail |
|---|---|---|
| Geographic Atrophy | D057092 | 1 associated lipids |
| Trophoblastic Tumor, Placental Site | D018245 | 1 associated lipids |
| Lordosis | D008141 | 1 associated lipids |
| Phenylketonuria, Maternal | D017042 | 1 associated lipids |
| Refsum Disease, Infantile | D052919 | 1 associated lipids |
| Pulmonary Valve Stenosis | D011666 | 1 associated lipids |
| Cerebrovascular Trauma | D020214 | 1 associated lipids |
| Histiocytoma, Malignant Fibrous | D051677 | 1 associated lipids |
| Hydroa Vacciniforme | D006837 | 1 associated lipids |
| Communication Disorders | D003147 | 1 associated lipids |
DHA
Dha is a lipid of Fatty Acyls (FA) class. Dha is associated with abnormalities such as Atherosclerosis, Consumption-archaic term for TB, Chronic disease, Cardiovascular Diseases and Diabetes Mellitus, Non-Insulin-Dependent. The involved functions are known as Inflammation, Oxidation, fatty acid oxidation, Fatty Acid Metabolism and Lipid Metabolism. Dha often locates in Hepatic, Protoplasm, Mucous Membrane, Epithelium and outer membrane. The associated genes with DHA are IMPACT gene, FATE1 gene, GAPDH gene, THOC4 gene and SLC33A1 gene. The related lipids are stearidonic acid, Fatty Acids, Total cholesterol, Lipopolysaccharides and Dietary Fatty Acid. The related experimental models are Mouse Model, Transgenic Model, Animal Disease Models and Arthritis, Experimental.
Cross Reference
Introduction
To understand associated biological information of DHA, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with DHA?
DHA is suspected in Cardiovascular Diseases, Obesity, Ischemia, Hypertensive disease, Coronary Arteriosclerosis, Cerebrovascular accident and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with DHA
PubChem Associated disorders and diseases
What pathways are associated with DHA
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with DHA?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with DHA?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with DHA?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with DHA?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with DHA?
Mouse Model
Mouse Model are used in the study 'Homeostatic regulation of photoreceptor cell integrity: significance of the potent mediator neuroprotectin D1 biosynthesized from docosahexaenoic acid: the Proctor Lecture.' (Bazan NG, 2007), Mouse Model are used in the study 'Omega-3 fatty acids EPA and DHA: health benefits throughout life.' (Swanson D et al., 2012), Mouse Model are used in the study 'Docosahexaenoic acid attenuates hepatic inflammation, oxidative stress, and fibrosis without decreasing hepatosteatosis in a Ldlr(-/-) mouse model of western diet-induced nonalcoholic steatohepatitis.' (Depner CM et al., 2013) and Mouse Model are used in the study 'Wax esters from the marine copepod Calanus finmarchicus reduce diet-induced obesity and obesity-related metabolic disorders in mice.' (Höper AC et al., 2014).
Transgenic Model
Transgenic Model are used in the study 'Loss of MAP function leads to hippocampal synapse loss and deficits in the Morris Water Maze with aging.' (Ma QL et al., 2014).
Animal Disease Models
Animal Disease Models are used in the study 'Fish oil increases muscle protein mass and modulates Akt/FOXO, TLR4, and NOD signaling in weanling piglets after lipopolysaccharide challenge.' (Liu Y et al., 2013).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with DHA
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Machová E et al. | The increase of choline acetyltransferase activity by docosahexaenoic acid in NG108-15 cells grown in serum-free medium is independent of its effect on cell growth. | 2006 | Neurochem. Res. | pmid:17004129 |
| Hashimoto M et al. | Docosahexaenoic acid-induced protective effect against impaired learning in amyloid beta-infused rats is associated with increased synaptosomal membrane fluidity. | 2006 | Clin. Exp. Pharmacol. Physiol. | pmid:17002670 |
| [Start of insulin therapy. How to ensure patient compliance?]. | 2006 | MMW Fortschr Med | pmid:16995354 | |
| Orikasa Y et al. | Recombinant production of docosahexaenoic acid in a polyketide biosynthesis mode in Escherichia coli. | 2006 | Biotechnol. Lett. | pmid:16988784 |
| Rao JS et al. | Dietary n-3 PUFA deprivation alters expression of enzymes of the arachidonic and docosahexaenoic acid cascades in rat frontal cortex. | 2007 | Mol. Psychiatry | pmid:16983392 |
| Rao JS et al. | n-3 polyunsaturated fatty acid deprivation in rats decreases frontal cortex BDNF via a p38 MAPK-dependent mechanism. | 2007 | Mol. Psychiatry | pmid:16983391 |
| Erkkilä AT et al. | Higher plasma docosahexaenoic acid is associated with reduced progression of coronary atherosclerosis in women with CAD. | 2006 | J. Lipid Res. | pmid:16983146 |
| Kao BT et al. | Mice raised on milk transgenically enriched with n-3 PUFA have increased brain docosahexaenoic acid. | 2006 | Lipids | pmid:16981432 |
| Marosvölgyi T et al. | [Fatty acid composition of human milk in mothers of preterm and full-term infants in the first three weeks of lactation]. | 2006 | Orv Hetil | pmid:16981419 |
| Hacioglu G et al. | Beneficial effects of docosahexaenoic acid on active avoidance performance in 1K-1C hypertensive rats. | 2007 | Neurobiol Learn Mem | pmid:16979916 |
| Yao HT et al. | The inhibitory effect of polyunsaturated fatty acids on human CYP enzymes. | 2006 | Life Sci. | pmid:16978661 |
| Pappas AC et al. | Maternal organo-selenium compounds and polyunsaturated fatty acids affect progeny performance and levels of selenium and docosahexaenoic acid in the chick tissues. | 2006 | Poult. Sci. | pmid:16977847 |
| Egert S et al. | Influence of three rapeseed oil-rich diets, fortified with alpha-linolenic acid, eicosapentaenoic acid or docosahexaenoic acid on the composition and oxidizability of low-density lipoproteins: results of a controlled study in healthy volunteers. | 2007 | Eur J Clin Nutr | pmid:16969378 |
| Yonezawa Y et al. | Inhibitory action of C22-fatty acids on DNA polymerases and DNA topoisomerases. | 2006 | Int. J. Mol. Med. | pmid:16964408 |
| Lee M and Bae MA | Docosahexaenoic acid induces apoptosis in CYP2E1-containing HepG2 cells by activating the c-Jun N-terminal protein kinase related mitochondrial damage. | 2007 | J. Nutr. Biochem. | pmid:16963249 |
| Tavilani H et al. | Decreased polyunsaturated and increased saturated fatty acid concentration in spermatozoa from asthenozoospermic males as compared with normozoospermic males. | 2006 | Andrologia | pmid:16961570 |
| Sanders TA et al. | Effect of varying the ratio of n-6 to n-3 fatty acids by increasing the dietary intake of alpha-linolenic acid, eicosapentaenoic and docosahexaenoic acid, or both on fibrinogen and clotting factors VII and XII in persons aged 45-70 y: the OPTILIP study. | 2006 | Am. J. Clin. Nutr. | pmid:16960164 |
| Nieminen LR et al. | Relationship between omega-3 fatty acids and plasma neuroactive steroids in alcoholism, depression and controls. | 2006 Oct-Nov | Prostaglandins Leukot. Essent. Fatty Acids | pmid:16959481 |
| Xu Y et al. | Di-(2-ethylhexyl)-phthalate affects lipid profiling in fetal rat brain upon maternal exposure. | 2007 | Arch. Toxicol. | pmid:16951938 |
| Morris T et al. | New perspectives on aspirin and the endogenous control of acute inflammatory resolution. | 2006 | ScientificWorldJournal | pmid:16951898 |
| McNamara RK and Carlson SE | Role of omega-3 fatty acids in brain development and function: potential implications for the pathogenesis and prevention of psychopathology. | 2006 Oct-Nov | Prostaglandins Leukot. Essent. Fatty Acids | pmid:16949263 |
| Dangour AD et al. | A randomised controlled trial investigating the effect of n-3 long-chain polyunsaturated fatty acid supplementation on cognitive and retinal function in cognitively healthy older people: the Older People And n-3 Long-chain polyunsaturated fatty acids (OPAL) study protocol [ISRCTN72331636]. | 2006 | Nutr J | pmid:16945130 |
| Mollard RC and Weiler HA | Dietary arachidonic acid and docosahexaenoic acid elevate femur calcium and reduce zinc content in piglets. | 2006 | Pediatr. Res. | pmid:16940244 |
| Kojima Y et al. | Different specificity of two types of Pseudomonas lipases for C20 fatty acids with a Delta5 unsaturated double bond and their application for selective concentration of fatty acids. | 2006 | J. Biosci. Bioeng. | pmid:16935251 |
| Hashimoto M et al. | Docosahexaenoic acid but not eicosapentaenoic acid withstands dietary cholesterol-induced decreases in platelet membrane fluidity. | 2006 | Mol. Cell. Biochem. | pmid:16933035 |
| Isbilen B et al. | Docosahexaenoic acid (omega-3) blocks voltage-gated sodium channel activity and migration of MDA-MB-231 human breast cancer cells. | 2006 | Int. J. Biochem. Cell Biol. | pmid:16931105 |
| Freeman MP | Omega-3 fatty acids and perinatal depression: a review of the literature and recommendations for future research. | 2006 Oct-Nov | Prostaglandins Leukot. Essent. Fatty Acids | pmid:16930971 |
| McNamara RK | The emerging role of omega-3 fatty acids in psychiatry. | 2006 Oct-Nov | Prostaglandins Leukot. Essent. Fatty Acids | pmid:16930969 |
| Serhan CN | Novel chemical mediators in the resolution of inflammation: resolvins and protectins. | 2006 | Anesthesiol Clin | pmid:16927933 |
| Burdge GC et al. | Lack of effect of meal fatty acid composition on postprandial lipid, glucose and insulin responses in men and women aged 50-65 years consuming their habitual diets. | 2006 | Br. J. Nutr. | pmid:16925854 |
| Helland IB et al. | Supplementation of n-3 fatty acids during pregnancy and lactation reduces maternal plasma lipid levels and provides DHA to the infants. | 2006 | J. Matern. Fetal. Neonatal. Med. | pmid:16923694 |
| German OL et al. | Docosahexaenoic acid prevents apoptosis of retina photoreceptors by activating the ERK/MAPK pathway. | 2006 | J. Neurochem. | pmid:16923163 |
| Mori TA | Omega-3 fatty acids and hypertension in humans. | 2006 | Clin. Exp. Pharmacol. Physiol. | pmid:16922818 |
| Hall JA et al. | The (n-3) fatty acid dose, independent of the (n-6) to (n-3) fatty acid ratio, affects the plasma fatty acid profile of normal dogs. | 2006 | J. Nutr. | pmid:16920851 |
| Bays H | Clinical overview of Omacor: a concentrated formulation of omega-3 polyunsaturated fatty acids. | 2006 | Am. J. Cardiol. | pmid:16919519 |
| Kotani S et al. | Dietary supplementation of arachidonic and docosahexaenoic acids improves cognitive dysfunction. | 2006 | Neurosci. Res. | pmid:16905216 |
| Butovich IA et al. | Dihydroxydocosahexaenoic acids of the neuroprotectin D family: synthesis, structure, and inhibition of human 5-lipoxygenase. | 2006 | J. Lipid Res. | pmid:16899822 |
| Bazan NG | The onset of brain injury and neurodegeneration triggers the synthesis of docosanoid neuroprotective signaling. | 2006 Jul-Aug | Cell. Mol. Neurobiol. | pmid:16897369 |
| Li Z et al. | Dehydroepiandrosterone sulfate prevents ischemia-induced impairment of long-term potentiation in rat hippocampal CA1 by up-regulating tyrosine phosphorylation of NMDA receptor. | 2006 | Neuropharmacology | pmid:16895729 |
| Fournier V et al. | Analysis of eicosapentaenoic and docosahexaenoic acid geometrical isomers formed during fish oil deodorization. | 2006 | J Chromatogr A | pmid:16893549 |
| Quilici S et al. | A cost-effectiveness analysis of n-3 PUFA (Omacor) treatment in post-MI patients. | 2006 | Int. J. Clin. Pract. | pmid:16893435 |
| Sliwinski S et al. | Polyunsaturated fatty acids: do they have a role in the pathophysiology of autism? | 2006 | Neuro Endocrinol. Lett. | pmid:16891996 |
| Ding WQ et al. | Clioquinol and docosahexaenoic acid act synergistically to kill tumor cells. | 2006 | Mol. Cancer Ther. | pmid:16891473 |
| Hussar DA | New drugs 06, part II. | 2006 | Nursing | pmid:16888514 |
| Owada Y et al. | Altered emotional behavioral responses in mice lacking brain-type fatty acid-binding protein gene. | 2006 | Eur. J. Neurosci. | pmid:16882015 |
| Jørgensen MH et al. | The composition of polyunsaturated fatty acids in erythrocytes of lactating mothers and their infants. | 2006 | Matern Child Nutr | pmid:16881912 |
| Hacioglu G et al. | The role of docosahexaenoic acid on visual evoked potentials in one kidney-one clip hypertension. | 2006 | Acta Ophthalmol Scand | pmid:16879569 |
| Saraswathy S et al. | Retinal microglial activation and chemotaxis by docosahexaenoic acid hydroperoxide. | 2006 | Invest. Ophthalmol. Vis. Sci. | pmid:16877440 |
| Milne GL et al. | Elevated oxidation of docosahexaenoic acid, 22:6 (n-3), in brain regions of rats undergoing ethanol withdrawal. | 2006 | Neurosci. Lett. | pmid:16875780 |
| Klingler M et al. | The effect of docosahexaenoic acid and folic acid supplementation on placental apoptosis and proliferation. | 2006 | Br. J. Nutr. | pmid:16870008 |
| Ouguerram K et al. | Effect of n-3 fatty acids on metabolism of apoB100-containing lipoprotein in type 2 diabetic subjects. | 2006 | Br. J. Nutr. | pmid:16869997 |
| Bakewell L et al. | Polyunsaturated fatty acid concentrations in young men and women consuming their habitual diets. | 2006 | Br. J. Nutr. | pmid:16869996 |
| Langdon JH | Has an aquatic diet been necessary for hominin brain evolution and functional development? | 2006 | Br. J. Nutr. | pmid:16869985 |
| Kubo K et al. | Induction of multidrug resistance-associated protein MRP3 in the liver of rats fed with docosahexaenoic acid. | 2006 | Biosci. Biotechnol. Biochem. | pmid:16861802 |
| Cao D et al. | Chronic daily administration of ethyl docosahexaenoate protects against gerbil brain ischemic damage through reduction of arachidonic acid liberation and accumulation. | 2007 | J. Nutr. Biochem. | pmid:16860980 |
| Shin SY et al. | Antibacterial activity of bioconverted eicosapentaenoic (EPA) and docosahexaenoic acid (DHA) against foodborne pathogenic bacteria. | 2007 | Int. J. Food Microbiol. | pmid:16860896 |
| Kindler DD et al. | Update on therapies for acute ischemic stroke. | 2000 | Neurosurg Focus | pmid:16859280 |
| Omega-3 fatty acids may prevent sudden cardiac death. | 2006 | Health News | pmid:16858748 | |
| Levant B et al. | Diet (n-3) polyunsaturated fatty acid content and parity interact to alter maternal rat brain phospholipid fatty acid composition. | 2006 | J. Nutr. | pmid:16857847 |
| Bouwstra H et al. | Neurologic condition of healthy term infants at 18 months: positive association with venous umbilical DHA status and negative association with umbilical trans-fatty acids. | 2006 | Pediatr. Res. | pmid:16857765 |
| Khan NA et al. | Docosahexaenoic acid inhibits cancer cell growth via p27Kip1, CDK2, ERK1/ERK2, and retinoblastoma phosphorylation. | 2006 | J. Lipid Res. | pmid:16847309 |
| Carlson SE et al. | Long-term feeding of formulas high in linolenic acid and marine oil to very low birth weight infants: phospholipid fatty acids. | 1991 | Pediatr. Res. | pmid:1684416 |
| Johnson EJ and Schaefer EJ | Potential role of dietary n-3 fatty acids in the prevention of dementia and macular degeneration. | 2006 | Am. J. Clin. Nutr. | pmid:16841859 |
| Breslow JL | n-3 fatty acids and cardiovascular disease. | 2006 | Am. J. Clin. Nutr. | pmid:16841857 |
| Arterburn LM et al. | Distribution, interconversion, and dose response of n-3 fatty acids in humans. | 2006 | Am. J. Clin. Nutr. | pmid:16841856 |
| Cheatham CL et al. | N-3 fatty acids and cognitive and visual acuity development: methodologic and conceptual considerations. | 2006 | Am. J. Clin. Nutr. | pmid:16841855 |
| Yavin E | Versatile roles of docosahexaenoic acid in the prenatal brain: from pro- and anti-oxidant features to regulation of gene expression. | 2006 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:16839753 |
| Ganga R et al. | Modulation of ACTH-induced cortisol release by polyunsaturated fatty acids in interrenal cells from gilthead seabream, Sparus aurata. | 2006 | J. Endocrinol. | pmid:16837609 |
| Murphy KJ et al. | Low dose supplementation with two different marine oils does not reduce pro-inflammatory eicosanoids and cytokines in vivo. | 2006 | Asia Pac J Clin Nutr | pmid:16837436 |
| Polozova A et al. | Effect of docosahexaenoic acid on tissue targeting and metabolism of plasma lipoproteins. | 2006 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:16837179 |
| Abe E et al. | A novel phosphatidylcholine which contains pentadecanoic acid at sn-1 and docosahexaenoic acid at sn-2 in Schizochytrium sp. F26-b. | 2006 | J. Biochem. | pmid:16829536 |
| Namani T et al. | Vesicles from docosahexaenoic acid. | 2007 | Colloids Surf B Biointerfaces | pmid:16829059 |
| Burdge GC | Metabolism of alpha-linolenic acid in humans. | 2006 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:16828546 |
| Weil A | Why I still take my daily fish oil. | 2006 | Time | pmid:16827433 |
| Niu K et al. | Dietary long-chain n-3 fatty acids of marine origin and serum C-reactive protein concentrations are associated in a population with a diet rich in marine products. | 2006 | Am. J. Clin. Nutr. | pmid:16825699 |
| Harmon SD et al. | Oxygenation of omega-3 fatty acids by human cytochrome P450 4F3B: effect on 20-hydroxyeicosatetraenoic acid production. | 2006 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:16820285 |
| GarcÃa-Ródenas CL et al. | Nutritional approach to restore impaired intestinal barrier function and growth after neonatal stress in rats. | 2006 | J. Pediatr. Gastroenterol. Nutr. | pmid:16819372 |
| Schønberg SA et al. | Closely related colon cancer cell lines display different sensitivity to polyunsaturated fatty acids, accumulate different lipid classes and downregulate sterol regulatory element-binding protein 1. | 2006 | FEBS J. | pmid:16817902 |
| Sakurai Y et al. | Effects of long-term continuous use of immune-enhancing enteral formula on nutritional and immunologic status in non-surgical patients. | 2006 Jul-Aug | Nutrition | pmid:16815486 |
| Rhodes PG et al. | Effects of different levels of intravenous alpha-linolenic acid and supplemental breast milk on red blood cell docosahexaenoic acid in very low birth-weight infants. | 1991 | J. Pediatr. Gastroenterol. Nutr. | pmid:1681044 |
| Bitsanis D et al. | Gestational diabetes mellitus enhances arachidonic and docosahexaenoic acids in placental phospholipids. | 2006 | Lipids | pmid:16808147 |
| Bryhn M et al. | The bioavailability and pharmacodynamics of different concentrations of omega-3 acid ethyl esters. | 2006 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:16806871 |
| Amiri-Jami M et al. | Enhancement of polyunsaturated fatty acid production by Tn5 transposon in Shewanella baltica. | 2006 | Biotechnol. Lett. | pmid:16799757 |
| Chiang N and Serhan CN | Cell-cell interaction in the transcellular biosynthesis of novel omega-3-derived lipid mediators. | 2006 | Methods Mol. Biol. | pmid:16799203 |
| Garelli A et al. | Docosahexaenoic acid promotes photoreceptor differentiation without altering Crx expression. | 2006 | Invest. Ophthalmol. Vis. Sci. | pmid:16799048 |
| McGuinness J et al. | Myocardial protection using an omega-3 fatty acid infusion: quantification and mechanism of action. | 2006 | J. Thorac. Cardiovasc. Surg. | pmid:16798305 |
| Roman AS et al. | Omega-3 fatty acids and decidual cell prostaglandin production in response to the inflammatory cytokine IL-1beta. | 2006 | Am. J. Obstet. Gynecol. | pmid:16792994 |
| Weldon SM et al. | Docosahexaenoic acid induces an anti-inflammatory profile in lipopolysaccharide-stimulated human THP-1 macrophages more effectively than eicosapentaenoic acid. | 2007 | J. Nutr. Biochem. | pmid:16781858 |
| Patel JV et al. | Effects of omega-3 polyunsaturated fatty acids on metabolically active hormones in patients post-myocardial infarction. | 2007 | Int. J. Cardiol. | pmid:16781788 |
| Bauer JE et al. | Docosahexaenoic acid accumulates in plasma of canine puppies raised on alpha-linolenic acid-rich milk during suckling but not when fed alpha-linolenic acid-rich diets after weaning. | 2006 | J. Nutr. | pmid:16772507 |
| Walser B et al. | Supplementation with omega-3 polyunsaturated fatty acids augments brachial artery dilation and blood flow during forearm contraction. | 2006 | Eur. J. Appl. Physiol. | pmid:16770472 |
| Wasowska I et al. | Influence of fish oil on ruminal biohydrogenation of C18 unsaturated fatty acids. | 2006 | Br. J. Nutr. | pmid:16768845 |
| Oksman M et al. | Impact of different saturated fatty acid, polyunsaturated fatty acid and cholesterol containing diets on beta-amyloid accumulation in APP/PS1 transgenic mice. | 2006 | Neurobiol. Dis. | pmid:16765602 |
| Morita E et al. | Docosahexaenoic acid production and lipid-body formation in Schizochytrium limacinum SR21. | 2006 May-Jun | Mar. Biotechnol. | pmid:16763939 |
| Hamazaki K et al. | Fish oil reduces tooth loss mainly through its anti-inflammatory effects? | 2006 | Med. Hypotheses | pmid:16759817 |
| Hamam F and Shahidi F | Synthesis of structured lipids containing medium-chain and omega-3 fatty acids. | 2006 | J. Agric. Food Chem. | pmid:16756372 |
| Schwab JM and Serhan CN | Lipoxins and new lipid mediators in the resolution of inflammation. | 2006 | Curr Opin Pharmacol | pmid:16750421 |
| López-Alarcón M et al. | Docosahexaenoic acid administered in the acute phase protects the nutritional status of septic neonates. | 2006 Jul-Aug | Nutrition | pmid:16750345 |
| Sublette ME et al. | Omega-3 polyunsaturated essential fatty acid status as a predictor of future suicide risk. | 2006 | Am J Psychiatry | pmid:16741213 |
| Nemets H et al. | Omega-3 treatment of childhood depression: a controlled, double-blind pilot study. | 2006 | Am J Psychiatry | pmid:16741212 |