DHA
Dha is a lipid of Fatty Acyls (FA) class. Dha is associated with abnormalities such as Atherosclerosis, Consumption-archaic term for TB, Chronic disease, Cardiovascular Diseases and Diabetes Mellitus, Non-Insulin-Dependent. The involved functions are known as Inflammation, Oxidation, fatty acid oxidation, Fatty Acid Metabolism and Lipid Metabolism. Dha often locates in Hepatic, Protoplasm, Mucous Membrane, Epithelium and outer membrane. The associated genes with DHA are IMPACT gene, FATE1 gene, GAPDH gene, THOC4 gene and SLC33A1 gene. The related lipids are stearidonic acid, Fatty Acids, Total cholesterol, Lipopolysaccharides and Dietary Fatty Acid. The related experimental models are Mouse Model, Transgenic Model, Animal Disease Models and Arthritis, Experimental.
Cross Reference
Introduction
To understand associated biological information of DHA, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with DHA?
DHA is suspected in Cardiovascular Diseases, Obesity, Ischemia, Hypertensive disease, Coronary Arteriosclerosis, Cerebrovascular accident and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with DHA
PubChem Associated disorders and diseases
What pathways are associated with DHA
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with DHA?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with DHA?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with DHA?
Related references are published most in these journals:
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What genes are associated with DHA?
Related references are published most in these journals:
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What common seen animal models are associated with DHA?
Mouse Model
Mouse Model are used in the study 'Homeostatic regulation of photoreceptor cell integrity: significance of the potent mediator neuroprotectin D1 biosynthesized from docosahexaenoic acid: the Proctor Lecture.' (Bazan NG, 2007), Mouse Model are used in the study 'Omega-3 fatty acids EPA and DHA: health benefits throughout life.' (Swanson D et al., 2012), Mouse Model are used in the study 'Docosahexaenoic acid attenuates hepatic inflammation, oxidative stress, and fibrosis without decreasing hepatosteatosis in a Ldlr(-/-) mouse model of western diet-induced nonalcoholic steatohepatitis.' (Depner CM et al., 2013) and Mouse Model are used in the study 'Wax esters from the marine copepod Calanus finmarchicus reduce diet-induced obesity and obesity-related metabolic disorders in mice.' (Höper AC et al., 2014).
Transgenic Model
Transgenic Model are used in the study 'Loss of MAP function leads to hippocampal synapse loss and deficits in the Morris Water Maze with aging.' (Ma QL et al., 2014).
Animal Disease Models
Animal Disease Models are used in the study 'Fish oil increases muscle protein mass and modulates Akt/FOXO, TLR4, and NOD signaling in weanling piglets after lipopolysaccharide challenge.' (Liu Y et al., 2013).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with DHA
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Bakker EC et al. | Early nutrition, essential fatty acid status and visual acuity of term infants at 7 months of age. | 1999 | Eur J Clin Nutr | pmid:10557000 |
| Elmore JS et al. | Effect of the polyunsaturated fatty acid composition of beef muscle on the profile of aroma volatiles. | 1999 | J. Agric. Food Chem. | pmid:10564028 |
| Purepa. | 1999 | Drugs R D | pmid:10566043 | |
| Agostoni C et al. | Long-chain polyunsaturated fatty acids in human milk. | 1999 | Acta Paediatr Suppl | pmid:10569226 |
| Freedman SD et al. | A membrane lipid imbalance plays a role in the phenotypic expression of cystic fibrosis in cftr(-/-) mice. | 1999 | Proc. Natl. Acad. Sci. U.S.A. | pmid:10570187 |
| Madsen L et al. | Eicosapentaenoic and docosahexaenoic acid affect mitochondrial and peroxisomal fatty acid oxidation in relation to substrate preference. | 1999 | Lipids | pmid:10574660 |
| Yoshida H et al. | Effect of dietary seal and fish oils on triacylglycerol metabolism in rats. | 1999 | J. Nutr. Sci. Vitaminol. | pmid:10575632 |
| Bisogno T et al. | Biosynthesis and inactivation of N-arachidonoylethanolamine (anandamide) and N-docosahexaenoylethanolamine in bovine retina. | 1999 | Arch. Biochem. Biophys. | pmid:10577359 |
| Jørgensen MH et al. | Does human milk DHA level affect functional outcome in infants? | 1999 | J Hum Lact | pmid:10578769 |
| Samples BL et al. | Polyunsaturated fatty acids enhance the heat induced stress response in rainbow trout (Oncorhynchus mykiss) leukocytes. | 1999 | Comp. Biochem. Physiol. B, Biochem. Mol. Biol. | pmid:10582313 |
| Norrish AE et al. | Prostate cancer risk and consumption of fish oils: a dietary biomarker-based case-control study. | 1999 | Br. J. Cancer | pmid:10584888 |
| Conquer JA et al. | Effect of supplementation with dietary seal oil on selected cardiovascular risk factors and hemostatic variables in healthy male subjects. | 1999 | Thromb. Res. | pmid:10588467 |
| Levy R and Herzberg GR | Hydrolysis of long-chain, n-3 fatty acid enriched chylomicrons by cardiac lipoprotein lipase. | 1999 | Can. J. Physiol. Pharmacol. | pmid:10588486 |
| Senkal M et al. | Outcome and cost-effectiveness of perioperative enteral immunonutrition in patients undergoing elective upper gastrointestinal tract surgery: a prospective randomized study. | 1999 | Arch Surg | pmid:10593328 |
| LeVine SM et al. | Microchemical analysis of retina layers in pigmented and albino rats by Fourier transform infrared microspectroscopy. | 1999 | Biochim. Biophys. Acta | pmid:10594378 |
| Kageyama K et al. | Cytotoxicity of docosahexaenoic acid and eicosapentaenoic acid in tumor cells and the dependence on binding to serum proteins and incorporation into intracellular lipids. | 2000 Jan-Feb | Oncol. Rep. | pmid:10601596 |
| Miyazaki M et al. | Dietary docosahexaenoic acid ameliorates, but rapeseed oil and safflower oil accelerate renal injury in stroke-prone spontaneously hypertensive rats as compared with soybean oil, which is associated with expression for renal transforming growth factor-beta, fibronectin and renin. | 2000 | Biochim. Biophys. Acta | pmid:10601699 |
| Retterstøl K et al. | The pathway from arachidonic to docosapentaenoic acid (20:4n-6 to 22:5n-6) and from eicosapentaenoic to docosahexaenoic acid (20:5n-3 to 22:6n-3) studied in testicular cells from immature rats. | 2000 | Biochim. Biophys. Acta | pmid:10601701 |
| Nitsan Z et al. | Enrichment of poultry products with omega3 fatty acids by dietary supplementation with the alga Nannochloropsis and mantur oil. | 1999 | J. Agric. Food Chem. | pmid:10606584 |
| McGahon BM et al. | Age-related changes in synaptic function: analysis of the effect of dietary supplementation with omega-3 fatty acids. | 1999 | Neuroscience | pmid:10613520 |