| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Stomach Ulcer | D013276 | 75 associated lipids |
| Kidney Failure, Chronic | D007676 | 51 associated lipids |
| Diabetes Mellitus | D003920 | 90 associated lipids |
| Hypoxia | D000860 | 23 associated lipids |
| Arrhythmias, Cardiac | D001145 | 42 associated lipids |
| Neovascularization, Pathologic | D009389 | 39 associated lipids |
| Adenocarcinoma | D000230 | 166 associated lipids |
| Breast Neoplasms | D001943 | 24 associated lipids |
| Pain | D010146 | 64 associated lipids |
DHA
Dha is a lipid of Fatty Acyls (FA) class. Dha is associated with abnormalities such as Atherosclerosis, Consumption-archaic term for TB, Chronic disease, Cardiovascular Diseases and Diabetes Mellitus, Non-Insulin-Dependent. The involved functions are known as Inflammation, Oxidation, fatty acid oxidation, Fatty Acid Metabolism and Lipid Metabolism. Dha often locates in Hepatic, Protoplasm, Mucous Membrane, Epithelium and outer membrane. The associated genes with DHA are IMPACT gene, FATE1 gene, GAPDH gene, THOC4 gene and SLC33A1 gene. The related lipids are stearidonic acid, Fatty Acids, Total cholesterol, Lipopolysaccharides and Dietary Fatty Acid. The related experimental models are Mouse Model, Transgenic Model, Animal Disease Models and Arthritis, Experimental.
Cross Reference
Introduction
To understand associated biological information of DHA, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with DHA?
DHA is suspected in Cardiovascular Diseases, Obesity, Ischemia, Hypertensive disease, Coronary Arteriosclerosis, Cerebrovascular accident and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with DHA
PubChem Associated disorders and diseases
What pathways are associated with DHA
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with DHA?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with DHA?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with DHA?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with DHA?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with DHA?
Mouse Model
Mouse Model are used in the study 'Homeostatic regulation of photoreceptor cell integrity: significance of the potent mediator neuroprotectin D1 biosynthesized from docosahexaenoic acid: the Proctor Lecture.' (Bazan NG, 2007), Mouse Model are used in the study 'Omega-3 fatty acids EPA and DHA: health benefits throughout life.' (Swanson D et al., 2012), Mouse Model are used in the study 'Docosahexaenoic acid attenuates hepatic inflammation, oxidative stress, and fibrosis without decreasing hepatosteatosis in a Ldlr(-/-) mouse model of western diet-induced nonalcoholic steatohepatitis.' (Depner CM et al., 2013) and Mouse Model are used in the study 'Wax esters from the marine copepod Calanus finmarchicus reduce diet-induced obesity and obesity-related metabolic disorders in mice.' (Höper AC et al., 2014).
Transgenic Model
Transgenic Model are used in the study 'Loss of MAP function leads to hippocampal synapse loss and deficits in the Morris Water Maze with aging.' (Ma QL et al., 2014).
Animal Disease Models
Animal Disease Models are used in the study 'Fish oil increases muscle protein mass and modulates Akt/FOXO, TLR4, and NOD signaling in weanling piglets after lipopolysaccharide challenge.' (Liu Y et al., 2013).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
NCBI Entrez Crosslinks
All references with DHA
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Lee HN et al. | Resolution of inflammation as a novel chemopreventive strategy. | 2013 | Semin Immunopathol | pmid:23370700 |
| Schantz MM et al. | Development of botanical and fish oil standard reference materials for fatty acids. | 2013 | Anal Bioanal Chem | pmid:23371533 |
| Teague H et al. | Dendritic cell activation, phagocytosis and CD69 expression on cognate T cells are suppressed by n-3 long-chain polyunsaturated fatty acids. | 2013 | Immunology | pmid:23373457 |
| Umhau JC et al. | Brain docosahexaenoic acid [DHA] incorporation and blood flow are increased in chronic alcoholics: a positron emission tomography study corrected for cerebral atrophy. | 2013 | PLoS ONE | pmid:24098376 |
| Renganathan K et al. | CEP biomarkers as potential tools for monitoring therapeutics. | 2013 | PLoS ONE | pmid:24098476 |
| Teague H et al. | DHA-fluorescent probe is sensitive to membrane order and reveals molecular adaptation of DHA in ordered lipid microdomains. | 2013 | J. Nutr. Biochem. | pmid:22841541 |
| Zong G et al. | Effects of flaxseed supplementation on erythrocyte fatty acids and multiple cardiometabolic biomarkers among Chinese with risk factors of metabolic syndrome. | 2013 | Eur J Nutr | pmid:23179200 |
| Meher AP et al. | Preconceptional omega-3 fatty acid supplementation on a micronutrient-deficient diet improves the reproductive cycle in Wistar rats. | 2013 | Reprod. Fertil. Dev. | pmid:23137932 |
| Betancor MB et al. | Oxidative status and histological changes in sea bass larvae muscle in response to high dietary content of docosahexaenoic acid DHA. | 2013 | J. Fish Dis. | pmid:23167568 |
| Herba CM et al. | Breastfeeding and early brain development: the Generation R study. | 2013 | Matern Child Nutr | pmid:23167730 |
| Hoshi T et al. | Mechanism of the modulation of BK potassium channel complexes with different auxiliary subunit compositions by the omega-3 fatty acid DHA. | 2013 | Proc. Natl. Acad. Sci. U.S.A. | pmid:23487786 |
| Gerstenblith AT et al. | Electroretinographic effects of omega-3 Fatty Acid supplementation on dry age-related macular degeneration. | 2013 | JAMA Ophthalmol | pmid:23494041 |
| Ramos-Loyo J et al. | Sex differences in lipid peroxidation and fatty acid levels in recent onset schizophrenia. | 2013 | Prog. Neuropsychopharmacol. Biol. Psychiatry | pmid:23421976 |
| Dallaire R et al. | Exposure to organochlorines and mercury through fish and marine mammal consumption: associations with growth and duration of gestation among Inuit newborns. | 2013 | Environ Int | pmid:23422685 |
| Nordgren TM et al. | Maresin-1 reduces the pro-inflammatory response of bronchial epithelial cells to organic dust. | 2013 | Respir. Res. | pmid:23663457 |
| Izquierdo MS et al. | Effects of dietary DHA and α-tocopherol on bone development, early mineralisation and oxidative stress in Sparus aurata (Linnaeus, 1758) larvae. | 2013 | Br. J. Nutr. | pmid:23046500 |
| Hara M et al. | Low levels of serum n-3 polyunsaturated fatty acids are associated with worse heart failure-free survival in patients after acute myocardial infarction. | 2013 | Circ. J. | pmid:23047296 |
| McNamara RK et al. | Lower docosahexaenoic acid concentrations in the postmortem prefrontal cortex of adult depressed suicide victims compared with controls without cardiovascular disease. | 2013 | J Psychiatr Res | pmid:23759469 |
| Ruiz-Lopez N et al. | Reconstitution of EPA and DHA biosynthesis in arabidopsis: iterative metabolic engineering for the synthesis of n-3 LC-PUFAs in transgenic plants. | 2013 | Metab. Eng. | pmid:23500000 |
| Recchiuti A | Resolvin D1 and its GPCRs in resolution circuits of inflammation. | 2013 | Prostaglandins Other Lipid Mediat. | pmid:23500003 |
| Gladyshev MI et al. | Production of EPA and DHA in aquatic ecosystems and their transfer to the land. | 2013 | Prostaglandins Other Lipid Mediat. | pmid:23500063 |
| Zhuang W et al. | Omega-3 polyunsaturated fatty acids reduce vascular endothelial growth factor production and suppress endothelial wound repair. | 2013 | J Cardiovasc Transl Res | pmid:22993129 |
| Moallem U et al. | Dietary α-linolenic acid from flaxseed oil improved folliculogenesis and IVF performance in dairy cows, similar to eicosapentaenoic and docosahexaenoic acids from fish oil. | 2013 | Reproduction | pmid:24062566 |
| Pacetti D et al. | Effect of spawning on furan fatty acid profile of edible muscle and organ tissues from sardine (Sardina pilchardus) and anchovy (Engraulis encrasicolus). | 2013 | J. Agric. Food Chem. | pmid:23531042 |
| Mozurkewich EL et al. | The Mothers, Omega-3, and Mental Health Study: a double-blind, randomized controlled trial. | 2013 | Am. J. Obstet. Gynecol. | pmid:23531328 |
| Romero VC et al. | Developmental programming for allergy: a secondary analysis of the Mothers, Omega-3, and Mental Health Study. | 2013 | Am. J. Obstet. Gynecol. | pmid:23531329 |
| Gao F et al. | Aging decreases rate of docosahexaenoic acid synthesis-secretion from circulating unesterified α-linolenic acid by rat liver. | 2013 | Age (Dordr) | pmid:22388930 |
| Erken HA et al. | Exercise and DHA prevent the negative effects of hypoxia on EEG and nerve conduction velocity. | 2013 | High Alt. Med. Biol. | pmid:24377343 |
| Tapsell LC et al. | Foods, nutrients or whole diets: effects of targeting fish and LCn3PUFA consumption in a 12mo weight loss trial. | 2013 | BMC Public Health | pmid:24369765 |
| van Valenberg HJ et al. | Concentrations of n-3 and n-6 fatty acids in Dutch bovine milk fat and their contribution to human dietary intake. | 2013 | J. Dairy Sci. | pmid:23664339 |
| Markhus MW et al. | Low omega-3 index in pregnancy is a possible biological risk factor for postpartum depression. | 2013 | PLoS ONE | pmid:23844041 |
| Brouwer IA et al. | Effect of alpha linolenic acid supplementation on serum prostate specific antigen (PSA): results from the alpha omega trial. | 2013 | PLoS ONE | pmid:24349086 |
| Zhang L et al. | Improving docosahexaenoic acid productivity of Schizochytrium sp. by a two-stage AEMR/shake mixed culture mode. | 2013 | Bioresour. Technol. | pmid:23751810 |
| Janczyk W et al. | Omega-3 fatty acids for treatment of non-alcoholic fatty liver disease: design and rationale of randomized controlled trial. | 2013 | BMC Pediatr | pmid:23702094 |
| Cortina MS et al. | Neuroprotectin D1 restores corneal nerve integrity and function after damage from experimental surgery. | 2013 | Invest. Ophthalmol. Vis. Sci. | pmid:23702780 |
| Hara M and Sakata Y | Polyunsaturated fatty acids in heart failure: reply. | 2013 | Circ. J. | pmid:23628916 |
| Chouinard-Watkins R et al. | Disturbance in uniformly 13C-labelled DHA metabolism in elderly human subjects carrying the apoE ε4 allele. | 2013 | Br. J. Nutr. | pmid:23631810 |
| Meyer BJ et al. | Assessing long-chain ω-3 polyunsaturated fatty acids: a tailored food-frequency questionnaire is better. | 2013 | Nutrition | pmid:22929186 |
| Kusunoki C et al. | Omega-3 polyunsaturated fatty acid has an anti-oxidant effect via the Nrf-2/HO-1 pathway in 3T3-L1 adipocytes. | 2013 | Biochem. Biophys. Res. Commun. | pmid:23131562 |
| Li C et al. | High efficient treatment of citric acid effluent by Chlorella vulgaris and potential biomass utilization. | 2013 | Bioresour. Technol. | pmid:23131649 |
| Lovegrove JA and Griffin BA | The acute and long-term effects of dietary fatty acids on vascular function in health and disease. | 2013 | Curr Opin Clin Nutr Metab Care | pmid:23299700 |
| Sadli N et al. | Effect of DHA and coenzymeQ10 against Aβ- and zinc-induced mitochondrial dysfunction in human neuronal cells. | 2013 | Cell. Physiol. Biochem. | pmid:23942088 |
| Rajasagi NK et al. | Neuroprotectin D1 reduces the severity of herpes simplex virus-induced corneal immunopathology. | 2013 | Invest. Ophthalmol. Vis. Sci. | pmid:23942967 |
| Chaung HC et al. | Docosahexaenoic acid and phosphatidylserine improves the antioxidant activities in vitro and in vivo and cognitive functions of the developing brain. | 2013 | Food Chem | pmid:23265497 |
| Akanbi TO et al. | Selective concentration of EPA and DHA using Thermomyces lanuginosus lipase is due to fatty acid selectivity and not regioselectivity. | 2013 | Food Chem | pmid:23265531 |
| Alicandro G et al. | A randomized placebo-controlled study on high-dose oral algal docosahexaenoic acid supplementation in children with cystic fibrosis. | 2013 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:23266209 |
| Orr SK et al. | Unesterified docosahexaenoic acid is protective in neuroinflammation. | 2013 | J. Neurochem. | pmid:23919613 |
| Stanley WC et al. | Evaluation of docosahexaenoic acid in a dog model of hypertension induced left ventricular hypertrophy. | 2013 | J Cardiovasc Transl Res | pmid:24065618 |
| Xiao G et al. | Eicosapentaenoic acid enhances heat stress-impaired intestinal epithelial barrier function in Caco-2 cells. | 2013 | PLoS ONE | pmid:24066055 |
| Delplanque B et al. | A dairy fat matrix providing alpha-linolenic acid (ALA) is better than a vegetable fat mixture to increase brain DHA accretion in young rats. | 2013 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:22884780 |