| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Stomach Ulcer | D013276 | 75 associated lipids |
| Kidney Failure, Chronic | D007676 | 51 associated lipids |
| Diabetes Mellitus | D003920 | 90 associated lipids |
| Hypoxia | D000860 | 23 associated lipids |
| Arrhythmias, Cardiac | D001145 | 42 associated lipids |
| Neovascularization, Pathologic | D009389 | 39 associated lipids |
| Adenocarcinoma | D000230 | 166 associated lipids |
| Breast Neoplasms | D001943 | 24 associated lipids |
| Pain | D010146 | 64 associated lipids |
DHA
Dha is a lipid of Fatty Acyls (FA) class. Dha is associated with abnormalities such as Atherosclerosis, Consumption-archaic term for TB, Chronic disease, Cardiovascular Diseases and Diabetes Mellitus, Non-Insulin-Dependent. The involved functions are known as Inflammation, Oxidation, fatty acid oxidation, Fatty Acid Metabolism and Lipid Metabolism. Dha often locates in Hepatic, Protoplasm, Mucous Membrane, Epithelium and outer membrane. The associated genes with DHA are IMPACT gene, FATE1 gene, GAPDH gene, THOC4 gene and SLC33A1 gene. The related lipids are stearidonic acid, Fatty Acids, Total cholesterol, Lipopolysaccharides and Dietary Fatty Acid. The related experimental models are Mouse Model, Transgenic Model, Animal Disease Models and Arthritis, Experimental.
Cross Reference
Introduction
To understand associated biological information of DHA, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with DHA?
DHA is suspected in Cardiovascular Diseases, Obesity, Ischemia, Hypertensive disease, Coronary Arteriosclerosis, Cerebrovascular accident and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with DHA
PubChem Associated disorders and diseases
What pathways are associated with DHA
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with DHA?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with DHA?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with DHA?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with DHA?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with DHA?
Mouse Model
Mouse Model are used in the study 'Homeostatic regulation of photoreceptor cell integrity: significance of the potent mediator neuroprotectin D1 biosynthesized from docosahexaenoic acid: the Proctor Lecture.' (Bazan NG, 2007), Mouse Model are used in the study 'Omega-3 fatty acids EPA and DHA: health benefits throughout life.' (Swanson D et al., 2012), Mouse Model are used in the study 'Docosahexaenoic acid attenuates hepatic inflammation, oxidative stress, and fibrosis without decreasing hepatosteatosis in a Ldlr(-/-) mouse model of western diet-induced nonalcoholic steatohepatitis.' (Depner CM et al., 2013) and Mouse Model are used in the study 'Wax esters from the marine copepod Calanus finmarchicus reduce diet-induced obesity and obesity-related metabolic disorders in mice.' (Höper AC et al., 2014).
Transgenic Model
Transgenic Model are used in the study 'Loss of MAP function leads to hippocampal synapse loss and deficits in the Morris Water Maze with aging.' (Ma QL et al., 2014).
Animal Disease Models
Animal Disease Models are used in the study 'Fish oil increases muscle protein mass and modulates Akt/FOXO, TLR4, and NOD signaling in weanling piglets after lipopolysaccharide challenge.' (Liu Y et al., 2013).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with DHA
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| pmid:26219922 | ||||
| pmid:26222126 | ||||
| Qin Y et al. | Fish Oil Supplements Lower Serum Lipids and Glucose in Correlation with a Reduction in Plasma Fibroblast Growth Factor 21 and Prostaglandin E2 in Nonalcoholic Fatty Liver Disease Associated with Hyperlipidemia: A Randomized Clinical Trial. | 2015 | PLoS ONE | pmid:26226139 |
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| pmid:26236990 | ||||
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| pmid:26247960 | ||||
| Valenzuela R et al. | Modification of Docosahexaenoic Acid Composition of Milk from Nursing Women Who Received Alpha Linolenic Acid from Chia Oil during Gestation and Nursing. | 2015 | Nutrients | pmid:26247968 |
| pmid:26248129 | ||||
| pmid:26249019 | ||||
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| pmid:26268080 | ||||
| pmid:26268328 | ||||
| Wijendran V et al. | Long-chain polyunsaturated fatty acids attenuate the IL-1β-induced proinflammatory response in human fetal intestinal epithelial cells. | 2015 | Pediatr. Res. | pmid:26270575 |
| pmid:26272430 | ||||
| pmid:26272871 | ||||
| pmid:26276744 | ||||
| pmid:26282164 | ||||
| Mason JK et al. | α-linolenic acid and docosahexaenoic acid, alone and combined with trastuzumab, reduce HER2-overexpressing breast cancer cell growth but differentially regulate HER2 signaling pathways. | 2015 | Lipids Health Dis | pmid:26282560 |
| pmid:26283657 | ||||
| Lehmann C et al. | Lipoxin and resolvin biosynthesis is dependent on 5-lipoxygenase activating protein. | 2015 | FASEB J. | pmid:26289316 |
| Stein K et al. | A role for 12/15-lipoxygenase-derived proresolving mediators in postoperative ileus: protectin DX-regulated neutrophil extravasation. | 2016 | J. Leukoc. Biol. | pmid:26292977 |
| pmid:26295255 | ||||
| pmid:26298403 | ||||
| pmid:26299378 | ||||
| Schwager J et al. | ω-3 PUFAs and Resveratrol Differently Modulate Acute and Chronic Inflammatory Processes. | 2015 | Biomed Res Int | pmid:26301248 |
| Cotogni P et al. | The Omega-3 Fatty Acid Docosahexaenoic Acid Modulates Inflammatory Mediator Release in Human Alveolar Cells Exposed to Bronchoalveolar Lavage Fluid of ARDS Patients. | 2015 | Biomed Res Int | pmid:26301250 |
| Croasdell A et al. | Resolvins attenuate inflammation and promote resolution in cigarette smoke-exposed human macrophages. | 2015 | Am. J. Physiol. Lung Cell Mol. Physiol. | pmid:26301452 |
| pmid:26303404 | ||||
| Lehtonen A et al. | The effect of the short-term administration of fish oil on serum lipoproteins in old people. | 1989 | Gerontology | pmid:2630386 |
| pmid:26305645 | ||||
| Chew EY et al. | Effect of Omega-3 Fatty Acids, Lutein/Zeaxanthin, or Other Nutrient Supplementation on Cognitive Function: The AREDS2 Randomized Clinical Trial. | 2015 | JAMA | pmid:26305649 |
| pmid:26307979 | ||||
| pmid:26315048 | ||||
| Cox R et al. | Resolvins Decrease Oxidative Stress Mediated Macrophage and Epithelial Cell Interaction through Decreased Cytokine Secretion. | 2015 | PLoS ONE | pmid:26317859 |
| pmid:26318978 | ||||
| Hiram R et al. | Resolvin E1 normalizes contractility, Ca2+ sensitivity and smooth muscle cell migration rate in TNF-α- and IL-6-pretreated human pulmonary arteries. | 2015 | Am. J. Physiol. Lung Cell Mol. Physiol. | pmid:26320154 |
| pmid:26320676 | ||||
| pmid:26321578 | ||||
| pmid:26322917 | ||||
| pmid:26325092 | ||||
| Mansara PP et al. | Differential Ratios of Omega Fatty Acids (AA/EPA+DHA) Modulate Growth, Lipid Peroxidation and Expression of Tumor Regulatory MARBPs in Breast Cancer Cell Lines MCF7 and MDA-MB-231. | 2015 | PLoS ONE | pmid:26325577 |
| pmid:26327595 | ||||
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| pmid:26335394 | ||||
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| pmid:26338174 | ||||
| pmid:26338453 | ||||
| Taylan A et al. | S1000A12, Chitotriosidase, and Resolvin D1 as Potential Biomarkers of Familial Mediterranean Fever. | 2015 | J. Korean Med. Sci. | pmid:26339162 |
| pmid:26339588 | ||||
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| Lim JY et al. | Biological Roles of Resolvins and Related Substances in the Resolution of Pain. | 2015 | Biomed Res Int | pmid:26339646 |
| pmid:26340264 | ||||
| Bobiński R and Mikulska M | The ins and outs of maternal-fetal fatty acid metabolism. | 2015 | Acta Biochim. Pol. | pmid:26345097 |
| pmid:26345987 | ||||
| pmid:26347247 | ||||
| pmid:26350999 | ||||
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| pmid:26361877 | ||||
| Bernhard W et al. | Developmental changes in polyunsaturated fetal plasma phospholipids and feto-maternal plasma phospholipid ratios and their association with bronchopulmonary dysplasia. | 2016 | Eur J Nutr | pmid:26363610 |
| pmid:26364855 | ||||
| pmid:26369878 | ||||
| pmid:26371149 | ||||
| Maekawa T et al. | Antagonistic effects of IL-17 and D-resolvins on endothelial Del-1 expression through a GSK-3β-C/EBPβ pathway. | 2015 | Nat Commun | pmid:26374165 |
| pmid:26374481 | ||||
| pmid:26377463 | ||||
| pmid:26378118 | ||||
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| pmid:26381084 | ||||
| Medema S et al. | Levels of Red Blood Cell Fatty Acids in Patients With Psychosis, Their Unaffected Siblings, and Healthy Controls. | 2016 | Schizophr Bull | pmid:26385764 |
| pmid:26386577 | ||||
| pmid:26388399 | ||||
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| pmid:26395388 | ||||
| Wang H et al. | Potential serum biomarkers from a metabolomics study of autism. | 2016 | J Psychiatry Neurosci | pmid:26395811 |
| pmid:26400435 | ||||
| Ross AB et al. | Herring and Beef Meals Lead to Differences in Plasma 2-Aminoadipic Acid, β-Alanine, 4-Hydroxyproline, Cetoleic Acid, and Docosahexaenoic Acid Concentrations in Overweight Men. | 2015 | J. Nutr. | pmid:26400963 |
| pmid:26401936 | ||||
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| Li R et al. | Enzymatic Synthesis of Refined Olive Oil-Based Structured Lipid Containing Omega -3 and -6 Fatty Acids for Potential Application in Infant Formula. | 2015 | J. Food Sci. | pmid:26408984 |
| pmid:26409038 |