| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Stomach Ulcer | D013276 | 75 associated lipids |
| Kidney Failure, Chronic | D007676 | 51 associated lipids |
| Diabetes Mellitus | D003920 | 90 associated lipids |
| Hypoxia | D000860 | 23 associated lipids |
| Arrhythmias, Cardiac | D001145 | 42 associated lipids |
| Neovascularization, Pathologic | D009389 | 39 associated lipids |
| Adenocarcinoma | D000230 | 166 associated lipids |
| Breast Neoplasms | D001943 | 24 associated lipids |
| Pain | D010146 | 64 associated lipids |
DHA
Dha is a lipid of Fatty Acyls (FA) class. Dha is associated with abnormalities such as Atherosclerosis, Consumption-archaic term for TB, Chronic disease, Cardiovascular Diseases and Diabetes Mellitus, Non-Insulin-Dependent. The involved functions are known as Inflammation, Oxidation, fatty acid oxidation, Fatty Acid Metabolism and Lipid Metabolism. Dha often locates in Hepatic, Protoplasm, Mucous Membrane, Epithelium and outer membrane. The associated genes with DHA are IMPACT gene, FATE1 gene, GAPDH gene, THOC4 gene and SLC33A1 gene. The related lipids are stearidonic acid, Fatty Acids, Total cholesterol, Lipopolysaccharides and Dietary Fatty Acid. The related experimental models are Mouse Model, Transgenic Model, Animal Disease Models and Arthritis, Experimental.
Cross Reference
Introduction
To understand associated biological information of DHA, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with DHA?
DHA is suspected in Cardiovascular Diseases, Obesity, Ischemia, Hypertensive disease, Coronary Arteriosclerosis, Cerebrovascular accident and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with DHA
PubChem Associated disorders and diseases
What pathways are associated with DHA
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with DHA?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with DHA?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with DHA?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with DHA?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with DHA?
Mouse Model
Mouse Model are used in the study 'Homeostatic regulation of photoreceptor cell integrity: significance of the potent mediator neuroprotectin D1 biosynthesized from docosahexaenoic acid: the Proctor Lecture.' (Bazan NG, 2007), Mouse Model are used in the study 'Omega-3 fatty acids EPA and DHA: health benefits throughout life.' (Swanson D et al., 2012), Mouse Model are used in the study 'Docosahexaenoic acid attenuates hepatic inflammation, oxidative stress, and fibrosis without decreasing hepatosteatosis in a Ldlr(-/-) mouse model of western diet-induced nonalcoholic steatohepatitis.' (Depner CM et al., 2013) and Mouse Model are used in the study 'Wax esters from the marine copepod Calanus finmarchicus reduce diet-induced obesity and obesity-related metabolic disorders in mice.' (Höper AC et al., 2014).
Transgenic Model
Transgenic Model are used in the study 'Loss of MAP function leads to hippocampal synapse loss and deficits in the Morris Water Maze with aging.' (Ma QL et al., 2014).
Animal Disease Models
Animal Disease Models are used in the study 'Fish oil increases muscle protein mass and modulates Akt/FOXO, TLR4, and NOD signaling in weanling piglets after lipopolysaccharide challenge.' (Liu Y et al., 2013).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with DHA
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| pmid:26638987 | ||||
| Gao J et al. | Neuroprotective effects of docosahexaenoic acid on hippocampal cell death and learning and memory impairments in a valproic acid-induced rat autism model. | 2016 | Int. J. Dev. Neurosci. | pmid:26639559 |
| pmid:26640797 | ||||
| pmid:26642316 | ||||
| pmid:26646031 | ||||
| pmid:26646102 | ||||
| Abdulnour RE et al. | Aspirin-triggered resolvin D1 is produced during self-resolving gram-negative bacterial pneumonia and regulates host immune responses for the resolution of lung inflammation. | 2016 | Mucosal Immunol | pmid:26647716 |
| pmid:26655290 | ||||
| Wang ZQ et al. | Docosahexaenoic Acid Attenuates Doxorubicin-induced Cytotoxicity and Inflammation by Suppressing NF-κB/iNOS/NO Signaling Pathway Activation in H9C2 Cardiac Cells. | 2016 | J. Cardiovasc. Pharmacol. | pmid:26657886 |
| pmid:26658738 | ||||
| pmid:26658812 | ||||
| pmid:26662260 | ||||
| pmid:26662863 | ||||
| Berge RK et al. | Krill oil reduces plasma triacylglycerol level and improves related lipoprotein particle concentration, fatty acid composition and redox status in healthy young adults - a pilot study. | 2015 | Lipids Health Dis | pmid:26666303 |
| Wang CW et al. | Maresin 1 Biosynthesis and Proresolving Anti-infective Functions with Human-Localized Aggressive Periodontitis Leukocytes. | 2015 | Infect. Immun. | pmid:26667839 |
| pmid:26671842 | ||||
| Gupta AK et al. | Double-blind, placebo-controlled study to evaluate the efficacy of fish oil and low-dose UVB in the treatment of psoriasis. | 1989 | Br. J. Dermatol. | pmid:2667615 |
| pmid:26679630 | ||||
| pmid:26682998 | ||||
| pmid:26683215 | ||||
| pmid:26685193 | ||||
| pmid:26687697 | ||||
| pmid:26687809 | ||||
| pmid:26689718 | ||||
| pmid:26690180 | ||||
| pmid:26694605 | ||||
| pmid:26697137 | ||||
| pmid:26697998 | ||||
| Liu Y et al. | Resolvin D1 protects against inflammation in experimental acute pancreatitis and associated lung injury. | 2016 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:26702138 |
| pmid:26703213 | ||||
| pmid:26705667 | ||||
| pmid:26707342 | ||||
| pmid:26707393 | ||||
| pmid:26709472 | ||||
| Lu Y et al. | Impedance spectroscopy analysis of human odorant binding proteins immobilized on nanopore arrays for biochemical detection. | 2016 | Biosens Bioelectron | pmid:26710343 |
| pmid:26710988 | ||||
| pmid:26714774 | ||||
| López-Luna P et al. | Fate of orally administered radioactive fatty acids in the late-pregnant rat. | 2016 | Am. J. Physiol. Endocrinol. Metab. | pmid:26714850 |
| pmid:26715431 | ||||
| pmid:26718448 | ||||
| pmid:26724495 | ||||
| pmid:26739870 | ||||
| pmid:26740205 | ||||
| pmid:26742060 | ||||
| pmid:26742061 | ||||
| Abeywardena MY et al. | Rise in DPA Following SDA-Rich Dietary Echium Oil Less Effective in Affording Anti-Arrhythmic Actions Compared to High DHA Levels Achieved with Fish Oil in Sprague-Dawley Rats. | 2016 | Nutrients | pmid:26742064 |
| Cerf ME and Herrera E | High Fat Diet Administration during Specific Periods of Pregnancy Alters Maternal Fatty Acid Profiles in the Near-Term Rat. | 2016 | Nutrients | pmid:26742067 |
| pmid:26743932 | ||||
| Jory J | Abnormal fatty acids in Canadian children with autism. | 2016 | Nutrition | pmid:26746679 |
| pmid:26747719 | ||||
| pmid:26748347 | ||||
| pmid:26749585 | ||||
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| pmid:26761122 | ||||
| pmid:26763196 | ||||
| pmid:26763232 | ||||
| Liu Q et al. | Dietary n-6:n-3 ratio and Vitamin E improve motility characteristics in association with membrane properties of boar spermatozoa. | 2017 Mar-Apr | Asian J. Androl. | pmid:26763547 |
| pmid:26765633 | ||||
| Bassuk SS et al. | Baseline characteristics of participants in the VITamin D and OmegA-3 TriaL (VITAL). | 2016 | Contemp Clin Trials | pmid:26767629 |
| pmid:26771636 | ||||
| pmid:26774753 | ||||
| pmid:26776055 | ||||
| pmid:26776249 | ||||
| pmid:26780261 | ||||
| pmid:26782308 | ||||
| Gold DR et al. | Lung VITAL: Rationale, design, and baseline characteristics of an ancillary study evaluating the effects of vitamin D and/or marine omega-3 fatty acid supplements on acute exacerbations of chronic respiratory disease, asthma control, pneumonia and lung function in adults. | 2016 | Contemp Clin Trials | pmid:26784651 |
| pmid:26790145 | ||||
| pmid:26791554 | ||||
| Georgieva R et al. | Phospholipase A2-Induced Remodeling Processes on Liquid-Ordered/Liquid-Disordered Membranes Containing Docosahexaenoic or Oleic Acid: A Comparison Study. | 2016 | Langmuir | pmid:26794691 |
| pmid:26796668 | ||||
| Seeger DR and Murphy EJ | Mouse Strain Impacts Fatty Acid Uptake and Trafficking in Liver, Heart, and Brain: A Comparison of C57BL/6 and Swiss Webster Mice. | 2016 | Lipids | pmid:26797754 |
| pmid:26802936 | ||||
| pmid:26802937 | ||||
| Qin X et al. | Brown but not white adipose cells synthesize omega-3 docosahexaenoic acid in culture. | 2016 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:26802938 |
| pmid:26803595 | ||||
| pmid:26805387 | ||||
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| pmid:26830472 |