| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Stomach Ulcer | D013276 | 75 associated lipids |
| Kidney Failure, Chronic | D007676 | 51 associated lipids |
| Diabetes Mellitus | D003920 | 90 associated lipids |
| Hypoxia | D000860 | 23 associated lipids |
| Arrhythmias, Cardiac | D001145 | 42 associated lipids |
| Neovascularization, Pathologic | D009389 | 39 associated lipids |
| Adenocarcinoma | D000230 | 166 associated lipids |
| Breast Neoplasms | D001943 | 24 associated lipids |
| Pain | D010146 | 64 associated lipids |
DHA
Dha is a lipid of Fatty Acyls (FA) class. Dha is associated with abnormalities such as Atherosclerosis, Consumption-archaic term for TB, Chronic disease, Cardiovascular Diseases and Diabetes Mellitus, Non-Insulin-Dependent. The involved functions are known as Inflammation, Oxidation, fatty acid oxidation, Fatty Acid Metabolism and Lipid Metabolism. Dha often locates in Hepatic, Protoplasm, Mucous Membrane, Epithelium and outer membrane. The associated genes with DHA are IMPACT gene, FATE1 gene, GAPDH gene, THOC4 gene and SLC33A1 gene. The related lipids are stearidonic acid, Fatty Acids, Total cholesterol, Lipopolysaccharides and Dietary Fatty Acid. The related experimental models are Mouse Model, Transgenic Model, Animal Disease Models and Arthritis, Experimental.
Cross Reference
Introduction
To understand associated biological information of DHA, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with DHA?
DHA is suspected in Cardiovascular Diseases, Obesity, Ischemia, Hypertensive disease, Coronary Arteriosclerosis, Cerebrovascular accident and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with DHA
PubChem Associated disorders and diseases
What pathways are associated with DHA
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with DHA?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with DHA?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with DHA?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with DHA?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with DHA?
Mouse Model
Mouse Model are used in the study 'Homeostatic regulation of photoreceptor cell integrity: significance of the potent mediator neuroprotectin D1 biosynthesized from docosahexaenoic acid: the Proctor Lecture.' (Bazan NG, 2007), Mouse Model are used in the study 'Omega-3 fatty acids EPA and DHA: health benefits throughout life.' (Swanson D et al., 2012), Mouse Model are used in the study 'Docosahexaenoic acid attenuates hepatic inflammation, oxidative stress, and fibrosis without decreasing hepatosteatosis in a Ldlr(-/-) mouse model of western diet-induced nonalcoholic steatohepatitis.' (Depner CM et al., 2013) and Mouse Model are used in the study 'Wax esters from the marine copepod Calanus finmarchicus reduce diet-induced obesity and obesity-related metabolic disorders in mice.' (Höper AC et al., 2014).
Transgenic Model
Transgenic Model are used in the study 'Loss of MAP function leads to hippocampal synapse loss and deficits in the Morris Water Maze with aging.' (Ma QL et al., 2014).
Animal Disease Models
Animal Disease Models are used in the study 'Fish oil increases muscle protein mass and modulates Akt/FOXO, TLR4, and NOD signaling in weanling piglets after lipopolysaccharide challenge.' (Liu Y et al., 2013).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with DHA
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Bourre JM et al. | Fatty acid alterations in liver peroxisomes from n-3-deficient mice. | 2006 | Ann. Nutr. Metab. | pmid:16407648 |
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| Flachs P et al. | Polyunsaturated fatty acids of marine origin induce adiponectin in mice fed a high-fat diet. | 2006 | Diabetologia | pmid:16397791 |
| Onuki Y et al. | Docosahexaenoic acid and eicosapentaenoic acid induce changes in the physical properties of a lipid bilayer model membrane. | 2006 | Chem. Pharm. Bull. | pmid:16394552 |
| Higuchi T et al. | Reduction in plasma glucose after lipid changes in mice fed fish oil, docosahexaenoic acid, and eicosapentaenoic acid diets. | 2006 | Ann. Nutr. Metab. | pmid:16391470 |
| Butovich IA | A one-step method of 10,17-dihydro(pero)xydocosahexa-4Z,7Z,11E,13Z,15E,19Z-enoic acid synthesis by soybean lipoxygenase. | 2006 | J. Lipid Res. | pmid:16391324 |
| Kulkarni A et al. | Successful outcome of pregnancy in a patient with familial hypertriglyceridaemia. | 2006 | J Obstet Gynaecol | pmid:16390715 |
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| Sørensen BM et al. | Storage lipid accumulation and acyltransferase action in developing flaxseed. | 2005 | Lipids | pmid:16382576 |
| Bryan DL et al. | Modulation of respiratory syncytial virus-induced prostaglandin E2 production by n-3 long-chain polyunsaturated fatty acids in human respiratory epithelium. | 2005 | Lipids | pmid:16382572 |
| Hussar DA | New drugs: pregabalin and omega-3-acid ethyl esters. | 2005 Nov-Dec | J Am Pharm Assoc (2003) | pmid:16381426 |
| Kumon Y et al. | A new labyrinthulid isolate that produces only docosahexaenoic acid. | 2006 Mar-Apr | Mar. Biotechnol. | pmid:16380808 |
| Birch DG | A randomized placebo-controlled clinical trial of docosahexaenoic acid (DHA) supplementation for X-linked retinitis pigmentosa. | 2005 | Retina (Philadelphia, Pa.) | pmid:16374336 |
| Robert SS | Production of eicosapentaenoic and docosahexaenoic acid-containing oils in transgenic land plants for human and aquaculture nutrition. | 2006 Mar-Apr | Mar. Biotechnol. | pmid:16372159 |
| Vaughan DK et al. | Light-induced exacerbation of retinal degeneration in a rat model of Smith-Lemli-Opitz syndrome. | 2006 | Exp. Eye Res. | pmid:16360150 |
| Song C et al. | Existence of lipid microdomains in bilayer of dipalmitoyl phosphatidylcholine (DPPC) and 1-stearoyl-2-docosahexenoyl phosphatidylserine (SDPS) and their perturbation by chlorpromazine: a 13C and 31P solid-state NMR study. | 2006 | Biophys. Chem. | pmid:16356624 |
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| Chen W et al. | Anti-inflammatory effect of docosahexaenoic acid on cytokine-induced adhesion molecule expression in human retinal vascular endothelial cells. | 2005 | Invest. Ophthalmol. Vis. Sci. | pmid:16249517 |
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| Lukiw WJ et al. | A role for docosahexaenoic acid-derived neuroprotectin D1 in neural cell survival and Alzheimer disease. | 2005 | J. Clin. Invest. | pmid:16151530 |
| Butovich IA | On the structure and synthesis of neuroprotectin D1, a novel anti-inflammatory compound of the docosahexaenoic acid family. | 2005 | J. Lipid Res. | pmid:16150835 |
| Kraffe E et al. | Docosahexaenoic acid- and eicosapentaenoic acid-enriched cardiolipin in the Manila clam Ruditapes philippinarum. | 2005 | Lipids | pmid:16149741 |
| Dalfó E et al. | Evidence of oxidative stress in the neocortex in incidental Lewy body disease. | 2005 | J. Neuropathol. Exp. Neurol. | pmid:16141792 |
| Machida T et al. | Docosahexaenoic acid enhances cyclooxygenase-2 induction by facilitating p44/42, but not p38, mitogen-activated protein kinase activation in rat vascular smooth muscle cells. | 2005 | J. Pharmacol. Sci. | pmid:16141635 |
| Decsi T et al. | Effect of N-3 polyunsaturated fatty acid supplementation in pregnancy: the Nuheal trial. | 2005 | Adv. Exp. Med. Biol. | pmid:16137113 |
| Lim SY et al. | An extraordinary degree of structural specificity is required in neural phospholipids for optimal brain function: n-6 docosapentaenoic acid substitution for docosahexaenoic acid leads to a loss in spatial task performance. | 2005 | J. Neurochem. | pmid:16135079 |
| Taha AY et al. | Despite transient ketosis, the classic high-fat ketogenic diet induces marked changes in fatty acid metabolism in rats. | 2005 | Metab. Clin. Exp. | pmid:16125522 |
| Esquenazi S et al. | Topical combination of NGF and DHA increases rabbit corneal nerve regeneration after photorefractive keratectomy. | 2005 | Invest. Ophthalmol. Vis. Sci. | pmid:16123410 |
| Thiébaut AC et al. | [Unsaturated fatty acids intake and breast cancer risk: epidemiological data review]. | 2005 | Bull Cancer | pmid:16123005 |
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