TRIPALMITIN is a lipid of Glycerolipids (GL) class. Tripalmitin is associated with abnormalities such as Atherosclerosis, Hypoalphalipoproteinemias, Cystic Fibrosis, PARKINSON DISEASE, LATE-ONSET and Obesity. The involved functions are known as 5-(carboxyamino)imidazole ribonucleotide mutase activity, Certification, phosphatidylcholine-sterol O-acyltransferase activity, Regulation and Uptake. Tripalmitin often locates in Blood, Hepatic, Body tissue, Gastric mucosa and Biopsy sample. The associated genes with TRIPALMITIN are PON1 gene, very high density lipoproteins, THEMIS gene, HEPATIC PROTEIN and chylomicron remnant. The related lipids are Fatty Acids, Total cholesterol, Nonesterified Fatty Acids, Palmitates and tristearin.
To understand associated biological information of TRIPALMITIN, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
TRIPALMITIN is suspected in Atherosclerosis, Fatty Liver, Cystic Fibrosis, Hypoalphalipoproteinemias, PARKINSON DISEASE, LATE-ONSET, Obesity and other diseases in descending order of the highest number of associated sentences.
| Disease | Cross reference | Weighted score | Related literature |
|---|
We collected disease MeSH terms mapped to the references associated with TRIPALMITIN
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Leishmaniasis, Visceral | D007898 | 13 associated lipids |
| Respiratory Distress Syndrome, Newborn | D012127 | 5 associated lipids |
| Cystic Fibrosis | D003550 | 65 associated lipids |
| Malabsorption Syndromes | D008286 | 16 associated lipids |
| HIV-Associated Lipodystrophy Syndrome | D039682 | 3 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
|---|
| Function | Cross reference | Weighted score | Related literatures |
|---|
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
| Gene | Cross reference | Weighted score | Related literatures |
|---|
There are no associated biomedical information in the current reference collection.
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| pmid: | ||||
| Reddy LH et al. | Etoposide-incorporated tripalmitin nanoparticles with different surface charge: formulation, characterization, radiolabeling, and biodistribution studies. | 2004 | AAPS J | pmid:15760108 |
| Kann B and Windbergs M | Chemical imaging of drug delivery systems with structured surfaces-a combined analytical approach of confocal raman microscopy and optical profilometry. | 2013 | AAPS J | pmid:23358922 |
| Windbergs M et al. | Two-step solid lipid extrusion as a process to modify dissolution behavior. | 2010 | AAPS PharmSciTech | pmid:20309654 |
| Iima R et al. | Thermal Behavior of F Nuclear Magnetic Resonance Signal of F-Containing Compound in Lipid Nano-Emulsion for Potential Tumor Diagnosis. | 2018 | AAPS PharmSciTech | pmid:29943279 |
| Vijayakumar A et al. | Quercetin-Loaded Solid Lipid Nanoparticle Dispersion with Improved Physicochemical Properties and Cellular Uptake. | 2017 | AAPS PharmSciTech | pmid:27368922 |
| Zimowski J et al. | Enzymatic synthesis of wax esters by cell-free preparations from Sinapis alba L roots. | 1982 | Acta Biochim. Pol. | pmid:7180324 |
| Szakonyi G and Zelkó R | [Taste-masking possibilities in solid dosage forms]. | 2012 | Acta Pharm Hung | pmid:22870781 |
| Lo CW et al. | Breath tests: principles, problems, and promise. | 1982 | Adv Pediatr | pmid:7180696 |
| Chattopadhyay P et al. | Production of solid lipid nanoparticle suspensions using supercritical fluid extraction of emulsions (SFEE) for pulmonary delivery using the AERx system. | 2007 | Adv. Drug Deliv. Rev. | pmid:17582648 |
| Sekhar RV et al. | Severely dysregulated disposal of postprandial triacylglycerols exacerbates hypertriacylglycerolemia in HIV lipodystrophy syndrome. | 2005 | Am. J. Clin. Nutr. | pmid:15941894 |
| KINSELL LW et al. | STUDIES WITH FAT EMULSIONS: METABOLISM OF INTRAVENOUSLY ADMINISTERED C14-TRIPALMITIN. | 1965 | Am. J. Clin. Nutr. | pmid:14270405 |
| Coniglio JG and Cate DL | Intestinal absorption of C14-palmitic acid and C14-tripalmitin in the rat. | Am. J. Clin. Nutr. | pmid:13811510 | |
| Meeker HE et al. | Clinical Experiences in 14C-tripalmitin breath test for fat malabsorption. | 1980 | Am. J. Gastroenterol. | pmid:7405923 |
| Bergstedt SE et al. | Effects of glycerol tripalmitate and glycerol trioleate on intestinal absorption of glycerol tristearate. | 1991 | Am. J. Physiol. | pmid:1872393 |
| McNamara JP et al. | Lipoprotein lipase and lipid metabolism in muscle and adipose tissues of Zucker rats. | 1982 | Am. J. Physiol. | pmid:7114287 |
| Vaidyanathan V et al. | Selective cannabinoid-1 receptor blockade benefits fatty acid and triglyceride metabolism significantly in weight-stable nonhuman primates. | 2012 | Am. J. Physiol. Endocrinol. Metab. | pmid:22761159 |
| King DM et al. | Bulk shear viscosities of endogenous and exogenous lung surfactants. | 2002 | Am. J. Physiol. Lung Cell Mol. Physiol. | pmid:11792632 |
| Pynn CJ et al. | Myristate is selectively incorporated into surfactant and decreases dipalmitoylphosphatidylcholine without functional impairment. | 2010 | Am. J. Physiol. Regul. Integr. Comp. Physiol. | pmid:20811010 |
| Jansen MA et al. | Evolving neural network optimization of cholesteryl ester separation by reversed-phase HPLC. | 2010 | Anal Bioanal Chem | pmid:20490467 |
| Lohninger A et al. | Determination of triacylglycerols in serum by capillary gas chromatography with trinonadecanoylglycerol as internal standard. | 1988 | Anal. Biochem. | pmid:3407934 |
| Gillin JS et al. | Malabsorption and mucosal abnormalities of the small intestine in the acquired immunodeficiency syndrome. | 1985 | Ann. Intern. Med. | pmid:3985513 |
| Pförringer D et al. | Antimicrobial Formulations of Absorbable Bone Substitute Materials as Drug Carriers Based on Calcium Sulfate. | 2016 | Antimicrob. Agents Chemother. | pmid:27067337 |
| Collins-Thompson DL et al. | Glycerol Ester Hydrolase Activity of Microbacterium thermosphactum. | 1971 | Appl Microbiol | pmid:16349896 |
| de Paula AV et al. | Screening of food grade lipases to be used in esterification and interesterification reactions of industrial interest. | 2010 | Appl. Biochem. Biotechnol. | pmid:19263247 |
| Yassin AA et al. | Effect of enzymatic interesterification on melting point of palm olein. | 2003 | Appl. Biochem. Biotechnol. | pmid:12909731 |
| Reis P et al. | Lipase-catalyzed reactions at interfaces of two-phase systems and microemulsions. | 2009 | Appl. Biochem. Biotechnol. | pmid:18795240 |
| Sebastian J and Kolattukudy PE | Purification and characterization of cutinase from a fluorescent Pseudomonas putida bacterial strain isolated from phyllosphere. | 1988 | Arch. Biochem. Biophys. | pmid:3130804 |
| Murphy JL et al. | Metabolic handling of 13C labelled tripalmitin in healthy controls and patients with cystic fibrosis. | 1998 | Arch. Dis. Child. | pmid:9771251 |
| Bennett AJ et al. | Regulation of hamster hepatic microsomal triglyceride transfer protein mRNA levels by dietary fats. | 1995 | Biochem. Biophys. Res. Commun. | pmid:7626061 |
| Banno Y et al. | Targeting of asialofetuin sugar chain-bearing liposomes to liver lysosomes. | 1983 | Biochem. Int. | pmid:6207826 |
| Needs EC and Welch VA | Intermolecular specificity of pancreatic lipase in the lipolysis of triacylglycerols containing phytanic acid. | 1978 | Biochem. J. | pmid:736903 |
| Griffiths LA and Smith GE | Metabolism of myricetin and related compounds in the rat. Metabolite formation in vivo and by the intestinal microflora in vitro. | 1972 | Biochem. J. | pmid:4655415 |
| Sakayama K et al. | Recombinant human tumour necrosis factor-alpha suppresses synthesis, activity and secretion of lipoprotein lipase in cultures of a human osteosarcoma cell line. | 1996 | Biochem. J. | pmid:8670156 |
| Bennett AJ et al. | Modulation of hepatic apolipoprotein B, 3-hydroxy-3-methylglutaryl-CoA reductase and low-density lipoprotein receptor mRNA and plasma lipoprotein concentrations by defined dietary fats. Comparison of trimyristin, tripalmitin, tristearin and triolein. | 1995 | Biochem. J. | pmid:7575449 |
| Han X et al. | Diabetes-induced changes in specific lipid molecular species in rat myocardium. | 2000 | Biochem. J. | pmid:11062060 |
| Salter AM et al. | Interactive effects of dietary cholesterol and saturated fat on low density lipoprotein cholesterol. | 1996 | Biochem. Soc. Trans. | pmid:8736838 |
| Bennoson J et al. | Influence of lipid content of testmeal on gastrointestinal handling and metabolic partitioning of dietary lipid in young men. | 1998 | Biochem. Soc. Trans. | pmid:9649863 |
| Hamilton JA | Interactions of triglycerides with phospholipids: incorporation into the bilayer structure and formation of emulsions. | 1989 | Biochemistry | pmid:2730879 |
| Uzawa H et al. | Determination of the lipase stereoselectivities using circular dichroism (CD); lipases produce chiral di-O-acylglycerols from achiral tri-O-acylglycerols. | 1993 | Biochim. Biophys. Acta | pmid:8323964 |
| Arrol S et al. | Lipoprotein secretion by the human hepatoma cell line Hep G2: differential rates of accumulation of apolipoprotein B and lipoprotein lipids in tissue culture media in response to albumin, glucose and oleate. | 1991 | Biochim. Biophys. Acta | pmid:1954247 |
| Kyriakides EC et al. | Alterations in phosphatidylcholine species and their reversal in pulmonary surfactant during essential fatty-acid deficiency. | 1976 | Biochim. Biophys. Acta | pmid:988841 |
| Paznokas JL and Kaplan A | Purification and properties of a triacylglycerol lipase from Mycobacterium phlei. | 1977 | Biochim. Biophys. Acta | pmid:18200 |
| Antony P et al. | Micro-scale flow cytometry-based and biochemical analysis of lipid signaling in primary B cell subpopulations. | 2007 | Biol Proced Online | pmid:18385809 |
| Erni C et al. | Evaluation of cationic solid lipid microparticles as synthetic carriers for the targeted delivery of macromolecules to phagocytic antigen-presenting cells. | 2002 | Biomaterials | pmid:12322988 |
| Hu WW et al. | Morphology and functions of astrocytes cultured on water-repellent fractal tripalmitin surfaces. | 2014 | Biomaterials | pmid:24894646 |
| Rago G et al. | CARS microscopy for the visualization of micrometer-sized iron oxide MRI contrast agents in living cells. | 2011 | Biomed Opt Express | pmid:21991541 |
| Wong PT et al. | Effect of cholesterol on structural and dynamic properties of tripalmitoyl glyceride. A high-pressure infrared spectroscopic study. | 1989 | Biophys. J. | pmid:2605300 |
| Baumeister W et al. | Radiation damage in tripalmitin layers studied by means of infrared spectroscopy and electron microscopy. | 1976 | Biophys. J. | pmid:938719 |
| Goodrum JW and Geller DP | Rapid thermogravimetric measurements of boiling points and vapor pressure of saturated medium- and long-chain triglycerides. | 2002 | Bioresour. Technol. | pmid:12137273 |