TRIPALMITIN is a lipid of Glycerolipids (GL) class. Tripalmitin is associated with abnormalities such as Atherosclerosis, Hypoalphalipoproteinemias, Cystic Fibrosis, PARKINSON DISEASE, LATE-ONSET and Obesity. The involved functions are known as 5-(carboxyamino)imidazole ribonucleotide mutase activity, Certification, phosphatidylcholine-sterol O-acyltransferase activity, Regulation and Uptake. Tripalmitin often locates in Blood, Hepatic, Body tissue, Gastric mucosa and Biopsy sample. The associated genes with TRIPALMITIN are PON1 gene, very high density lipoproteins, THEMIS gene, HEPATIC PROTEIN and chylomicron remnant. The related lipids are Fatty Acids, Total cholesterol, Nonesterified Fatty Acids, Palmitates and tristearin.
To understand associated biological information of TRIPALMITIN, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
TRIPALMITIN is suspected in Atherosclerosis, Fatty Liver, Cystic Fibrosis, Hypoalphalipoproteinemias, PARKINSON DISEASE, LATE-ONSET, Obesity and other diseases in descending order of the highest number of associated sentences.
| Disease | Cross reference | Weighted score | Related literature |
|---|
We collected disease MeSH terms mapped to the references associated with TRIPALMITIN
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Leishmaniasis, Visceral | D007898 | 13 associated lipids |
| Respiratory Distress Syndrome, Newborn | D012127 | 5 associated lipids |
| Cystic Fibrosis | D003550 | 65 associated lipids |
| Malabsorption Syndromes | D008286 | 16 associated lipids |
| HIV-Associated Lipodystrophy Syndrome | D039682 | 3 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
|---|
| Function | Cross reference | Weighted score | Related literatures |
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| Lipid concept | Cross reference | Weighted score | Related literatures |
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| Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Kuo YC and Chung CY | Solid lipid nanoparticles comprising internal Compritol 888 ATO, tripalmitin and cacao butter for encapsulating and releasing stavudine, delavirdine and saquinavir. | 2011 | Colloids Surf B Biointerfaces | pmid:21865017 |
| Kato T et al. | Palmitate impairs and eicosapentaenoate restores insulin secretion through regulation of SREBP-1c in pancreatic islets. | 2008 | Diabetes | pmid:18458149 |
| Moffitt JH et al. | Adverse physicochemical properties of tripalmitin in beta cells lead to morphological changes and lipotoxicity in vitro. | 2005 | Diabetologia | pmid:16094531 |
| Collins SC et al. | Long-term exposure of mouse pancreatic islets to oleate or palmitate results in reduced glucose-induced somatostatin and oversecretion of glucagon. | 2008 | Diabetologia | pmid:18622593 |
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| Witzleb R et al. | Solid lipid extrusion with small die diameters--electrostatic charging, taste masking and continuous production. | 2011 | Eur J Pharm Biopharm | pmid:20940049 |
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| Windbergs M et al. | Influence of structural variations on drug release from lipid/polyethylene glycol matrices. | 2009 | Eur J Pharm Sci | pmid:19406229 |
| Lopes R et al. | Lipid nanoparticles containing oryzalin for the treatment of leishmaniasis. | 2012 | Eur J Pharm Sci | pmid:21983568 |
| Cavalli R et al. | Preparation and characterization of solid lipid nanospheres containing paclitaxel. | 2000 | Eur J Pharm Sci | pmid:10838020 |
| Noiriel A et al. | Expression in yeast of a novel phospholipase A1 cDNA from Arabidopsis thaliana. | 2004 | Eur. J. Biochem. | pmid:15355352 |
| Royter M et al. | Thermostable lipases from the extreme thermophilic anaerobic bacteria Thermoanaerobacter thermohydrosulfuricus SOL1 and Caldanaerobacter subterraneus subsp. tengcongensis. | 2009 | Extremophiles | pmid:19579003 |
| Kornblatt JA et al. | Structure-activity relationships of wheat flavone O-methyltransferase: a homodimer of convenience. | 2008 | FEBS J. | pmid:18397325 |