7-octadecynoic acid

7-octadecynoic acid is a lipid of Fatty Acyls (FA) class.

Cross Reference

There are no associated biomedical information in the current reference collection.

Current reference collection contains 19785 references associated with 7-octadecynoic acid in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.


Here are additional resources we collected from PubChem and MeSH for 7-octadecynoic acid

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 7-octadecynoic acid

MeSH term MeSH ID Detail
Atrial Remodeling D064752 1 associated lipids
Vascular Calcification D061205 1 associated lipids
Angina, Stable D060050 2 associated lipids
Bisphosphonate-Associated Osteonecrosis of the Jaw D059266 1 associated lipids
Osteoporotic Fractures D058866 1 associated lipids
Peripheral Arterial Disease D058729 7 associated lipids
Plaque, Atherosclerotic D058226 7 associated lipids
Peri-Implantitis D057873 1 associated lipids
Primary Myelofibrosis D055728 6 associated lipids
Chronic Periodontitis D055113 1 associated lipids
Osteophyte D054850 2 associated lipids
Hyperphosphatemia D054559 1 associated lipids
Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative D054438 1 associated lipids
No-Reflow Phenomenon D054318 2 associated lipids
Acute Coronary Syndrome D054058 11 associated lipids
Hypercalciuria D053565 4 associated lipids
Renal Insufficiency, Chronic D051436 9 associated lipids
Fractures, Bone D050723 4 associated lipids
Arteriolosclerosis D050379 1 associated lipids
Atherosclerosis D050197 85 associated lipids
Dyslipidemias D050171 7 associated lipids
Hashimoto Disease D050031 1 associated lipids
Hyperparathyroidism, Primary D049950 1 associated lipids
Diabetes Complications D048909 4 associated lipids
Hypertension, Pregnancy-Induced D046110 2 associated lipids
Scleroderma, Limited D045745 1 associated lipids
Glucose Metabolism Disorders D044882 3 associated lipids
Malnutrition D044342 6 associated lipids
Irritable Bowel Syndrome D043183 8 associated lipids
Mastocytoma D034801 3 associated lipids
Hearing Loss D034381 3 associated lipids
Pulmonary Disease, Chronic Obstructive D029424 16 associated lipids
Spondylarthropathies D025242 1 associated lipids
Spondylarthritis D025241 1 associated lipids
Metabolic Syndrome D024821 44 associated lipids
Coronary Stenosis D023921 6 associated lipids
Carcinoma, Pancreatic Ductal D021441 6 associated lipids
Multiple Sclerosis, Relapsing-Remitting D020529 7 associated lipids
Multiple Sclerosis, Chronic Progressive D020528 3 associated lipids
Brain Infarction D020520 17 associated lipids
Osteoarthritis, Knee D020370 13 associated lipids
Lithiasis D020347 2 associated lipids
Ventricular Remodeling D020257 28 associated lipids
Tooth Ankylosis D020254 1 associated lipids
Venous Thrombosis D020246 11 associated lipids
Intracranial Hemorrhage, Traumatic D020198 1 associated lipids
Sleep Apnea, Obstructive D020181 9 associated lipids
Genetic Predisposition to Disease D020022 24 associated lipids
Hepatitis C, Chronic D019698 12 associated lipids
Hot Flashes D019584 5 associated lipids
Bone Marrow Neoplasms D019046 2 associated lipids
Myositis, Inclusion Body D018979 3 associated lipids
Sepsis D018805 11 associated lipids
Arthralgia D018771 8 associated lipids
Systemic Inflammatory Response Syndrome D018746 4 associated lipids
Breast Neoplasms, Male D018567 1 associated lipids
Bone Demineralization, Pathologic D018488 1 associated lipids
Ventricular Dysfunction, Left D018487 33 associated lipids
Cholesteatoma, Middle Ear D018424 2 associated lipids
Foot Injuries D018409 1 associated lipids
Alphavirus Infections D018354 1 associated lipids
Hemangioma, Capillary D018324 1 associated lipids
Neoplasms, Squamous Cell D018307 1 associated lipids
Carcinoma, Neuroendocrine D018278 2 associated lipids
Carcinoma, Medullary D018276 2 associated lipids
Carcinoma, Lobular D018275 4 associated lipids
Carcinoma, Ductal, Breast D018270 19 associated lipids
Adrenocortical Adenoma D018246 1 associated lipids
Fibroma, Ossifying D018214 1 associated lipids
Giant Cell Tumor of Bone D018212 1 associated lipids
Lymphangioleiomyomatosis D018192 1 associated lipids
Bone Cysts, Aneurysmal D017824 2 associated lipids
Diabetic Foot D017719 1 associated lipids
Periodontal Attachment Loss D017622 7 associated lipids
Microvascular Angina D017566 2 associated lipids
Aortic Aneurysm, Abdominal D017544 5 associated lipids
Myocardial Ischemia D017202 11 associated lipids
beta-Thalassemia D017086 5 associated lipids
Arthritis, Reactive D016918 3 associated lipids
Carotid Stenosis D016893 15 associated lipids
POEMS Syndrome D016878 1 associated lipids
Pasteurellaceae Infections D016871 2 associated lipids
Bacteroidaceae Infections D016866 2 associated lipids
Leishmaniasis, Cutaneous D016773 6 associated lipids
Diabetes, Gestational D016640 8 associated lipids
Severe Combined Immunodeficiency D016511 1 associated lipids
Peripheral Vascular Diseases D016491 8 associated lipids
Bacteremia D016470 9 associated lipids
Prosthesis-Related Infections D016459 7 associated lipids
Alveolar Bone Loss D016301 10 associated lipids
Fractures, Stress D015775 2 associated lipids
Mammary Neoplasms, Animal D015674 27 associated lipids
Osteoporosis, Postmenopausal D015663 4 associated lipids
HIV Infections D015658 20 associated lipids
Histiocytosis, Non-Langerhans-Cell D015616 4 associated lipids
Hyperostosis D015576 1 associated lipids
Arthritis, Psoriatic D015535 3 associated lipids
Leukemia, Lymphocytic, Chronic, B-Cell D015451 25 associated lipids
Weight Loss D015431 56 associated lipids
Weight Gain D015430 101 associated lipids
Per page 10 20 50 100 | Total 298

All references with 7-octadecynoic acid

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Authors Title Published Journal PubMed Link
Sakiyama H et al. Establishment and characterization of macrophage-like cell lines expressing osteoclast-specific markers. 2001 J. Bone Miner. Metab. pmid:11448014
Choi Y et al. Osteoclastogenesis is enhanced by activated B cells but suppressed by activated CD8(+) T cells. 2001 Eur. J. Immunol. pmid:11449372
Kanzaki H et al. Dual regulation of osteoclast differentiation by periodontal ligament cells through RANKL stimulation and OPG inhibition. 2001 J. Dent. Res. pmid:11379890
Hein GE [Pathophysiology of bone loss in rheumatic diseases--do bone markers help in monitoring?]. 2001 Z Rheumatol pmid:11383046
Morony S et al. Osteoprotegerin inhibits osteolysis and decreases skeletal tumor burden in syngeneic and nude mouse models of experimental bone metastasis. 2001 Cancer Res. pmid:11389072
Kim KJ et al. Osteoprotegerin inhibits in vitro mouse osteoclast formation induced by joint fluid from failed total hip arthroplasty. 2001 J. Biomed. Mater. Res. pmid:11410897
Abu-Amer Y IL-4 abrogates osteoclastogenesis through STAT6-dependent inhibition of NF-kappaB. 2001 J. Clin. Invest. pmid:11390419
Kon T et al. Expression of osteoprotegerin, receptor activator of NF-kappaB ligand (osteoprotegerin ligand) and related proinflammatory cytokines during fracture healing. 2001 J. Bone Miner. Res. pmid:11393777
Fazzalari NL et al. The ratio of messenger RNA levels of receptor activator of nuclear factor kappaB ligand to osteoprotegerin correlates with bone remodeling indices in normal human cancellous bone but not in osteoarthritis. 2001 J. Bone Miner. Res. pmid:11393778
Bekker PJ et al. The effect of a single dose of osteoprotegerin in postmenopausal women. 2001 J. Bone Miner. Res. pmid:11204435
Kikuchi T et al. Gene expression of osteoclast differentiation factor is induced by lipopolysaccharide in mouse osteoblasts via Toll-like receptors. 2001 J. Immunol. pmid:11207318
O'Brien EA et al. Osteoprotegerin is produced when prostaglandin synthesis is inhibited causing osteoclasts to detach from the surface of mouse parietal bone and attach to the endocranial membrane. 2001 Bone pmid:11182380
Zhang YH et al. Tumor necrosis factor-alpha (TNF) stimulates RANKL-induced osteoclastogenesis via coupling of TNF type 1 receptor and RANK signaling pathways. 2001 J. Biol. Chem. pmid:11032840
Goltzman D Osteolysis and cancer. 2001 J. Clin. Invest. pmid:11375409
Zhang J et al. Osteoprotegerin inhibits prostate cancer-induced osteoclastogenesis and prevents prostate tumor growth in the bone. 2001 J. Clin. Invest. pmid:11375413
Kostenuik PJ and Shalhoub V Osteoprotegerin: a physiological and pharmacological inhibitor of bone resorption. 2001 Curr. Pharm. Des. pmid:11375772
Stejskal D et al. Osteoprotegerin, RANK, RANKL. 2001 Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub pmid:12426773
Stejskal D et al. Osteoprotegerin and bone density. 2001 Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub pmid:12426776
Takemura M et al. Relationship between osteoprotegerin/osteoclastogenesis inhibitory factor concentration in synovial fluid and disease severity in individuals with osteoarthritis of the knee. 2001 Metab. Clin. Exp. pmid:11172466
Gravallese EM et al. The role of TNF-receptor family members and other TRAF-dependent receptors in bone resorption. 2001 Arthritis Res. pmid:11178122
Makiishi-Shimobayashi C et al. Interleukin-18 up-regulates osteoprotegerin expression in stromal/osteoblastic cells. 2001 Biochem. Biophys. Res. Commun. pmid:11181055
Lories RJ and Luyten FP Osteoprotegerin and osteoprotegerin-ligand balance: a new paradigm in bone metabolism providing new therapeutic targets. 2001 Clin. Rheumatol. pmid:11254237
Wan M et al. Transcriptional mechanisms of bone morphogenetic protein-induced osteoprotegrin gene expression. 2001 J. Biol. Chem. pmid:11139569
Browner WS et al. Associations of serum osteoprotegerin levels with diabetes, stroke, bone density, fractures, and mortality in elderly women. 2001 J. Clin. Endocrinol. Metab. pmid:11158021
Hofbauer LC and Heufelder AE [Osteoprotegerin ligand and osteoprotegerin: new concepts of the pathogenesis and therapy of metabolic bone diseases]. 2001 Dtsch. Med. Wochenschr. pmid:11233883
Bolon B et al. Adenoviral delivery of osteoprotegerin ameliorates bone resorption in a mouse ovariectomy model of osteoporosis. 2001 Mol. Ther. pmid:11237676
Sasaki N et al. Glucocorticoid decreases circulating osteoprotegerin (OPG): possible mechanism for glucocorticoid induced osteoporosis. 2001 Nephrol. Dial. Transplant. pmid:11239019
Takeuchi T et al. Adrenergic stimulation of osteoclastogenesis mediated by expression of osteoclast differentiation factor in MC3T3-E1 osteoblast-like cells. 2001 Biochem. Pharmacol. pmid:11239501
Mori K et al. Cross-talk between RANKL and FRP-1/CD98 Systems: RANKL-mediated osteoclastogenesis is suppressed by an inhibitory anti-CD98 heavy chain mAb and CD98-mediated osteoclastogenesis is suppressed by osteoclastogenesis inhibitory factor. 2001 Cell. Immunol. pmid:11243701
Hofbauer LC et al. Effects of immunosuppressants on receptor activator of NF-kappaB ligand and osteoprotegerin production by human osteoblastic and coronary artery smooth muscle cells. 2001 Biochem. Biophys. Res. Commun. pmid:11162519
Nemec K and Schubert-Zsilavecz M [Future therapies for metabolic bone diseases. New concepts and targets]. 2001 Pharm Unserer Zeit pmid:11715689
Kuntz KA et al. An immunohistochemical study of osteoprotegerin in the human dental pulp. 2001 J Endod pmid:11716077
Hofbauer LC and Schoppet M Serum measurement of osteoprotegerin--clinical relevance and potential applications. 2001 Eur. J. Endocrinol. pmid:11720890
Ueland T et al. Increased serum osteoprotegerin in disorders characterized by persistent immune activation or glucocorticoid excess--possible role in bone homeostasis. 2001 Eur. J. Endocrinol. pmid:11720891
Chikazu D et al. Regulation of osteoclast differentiation by fibroblast growth factor 2: stimulation of receptor activator of nuclear factor kappaB ligand/osteoclast differentiation factor expression in osteoblasts and inhibition of macrophage colony-stimulating factor function in osteoclast precursors. 2001 J. Bone Miner. Res. pmid:11697804
Khosla S Minireview: the OPG/RANKL/RANK system. 2001 Endocrinology pmid:11713196
Seidel C et al. Serum osteoprotegerin levels are reduced in patients with multiple myeloma with lytic bone disease. 2001 Blood pmid:11568016
Fukagawa M et al. Skeletal resistance to pth as a basic abnormality underlying uremic bone diseases. 2001 Am. J. Kidney Dis. pmid:11576943
Sato T et al. Osteoprotegerin levels before and after renal transplantation. 2001 Am. J. Kidney Dis. pmid:11576949
Feuerherm AJ et al. Elevated levels of osteoprotegerin (OPG) and hepatocyte growth factor (HGF) in rheumatoid arthritis. 2001 Scand. J. Rheumatol. pmid:11578019
Sakai E et al. Characterization of phagosomal subpopulations along endocytic routes in osteoclasts and macrophages. 2001 J. Biochem. pmid:11726283
Quinn JM et al. Transforming growth factor beta affects osteoclast differentiation via direct and indirect actions. 2001 J. Bone Miner. Res. pmid:11585342
Choi SJ et al. Osteoclast inhibitory peptide 2 inhibits osteoclast formation via its C-terminal fragment. 2001 J. Bone Miner. Res. pmid:11585344
Miyamoto T et al. Bifurcation of osteoclasts and dendritic cells from common progenitors. 2001 Blood pmid:11588053
Pearse RN et al. Multiple myeloma disrupts the TRANCE/ osteoprotegerin cytokine axis to trigger bone destruction and promote tumor progression. 2001 Proc. Natl. Acad. Sci. U.S.A. pmid:11562486
Kostenuik PJ et al. OPG and PTH-(1-34) have additive effects on bone density and mechanical strength in osteopenic ovariectomized rats. 2001 Endocrinology pmid:11564687
Marco-Mingot M et al. Lack of mutations in the RANK gene in Spanish patients with Paget disease of bone. 2001 Clin. Genet. pmid:11531977
Raffai RL et al. Introduction of human apolipoprotein E4 "domain interaction" into mouse apolipoprotein E. 2001 Proc. Natl. Acad. Sci. U.S.A. pmid:11553788
Hofbauer LC and Schoppet M Osteoprotegerin: a link between osteoporosis and arterial calcification? 2001 Lancet pmid:11498208
Sakai A et al. 1alpha-Hydroxyvitamin D3 suppresses trabecular bone resorption by inhibiting osteoclastogenic potential in bone marrow cells after ovariectomy in mice. 2001 J. Bone Miner. Metab. pmid:11498729
Ikeda T et al. Expression profiles of receptor activator of nuclear factor kappaB ligand, receptor activator of nuclear factor kappaB, and osteoprotegerin messenger RNA in aged and ovariectomized rat bones. 2001 J. Bone Miner. Res. pmid:11499864
Thomas GP et al. Changing RANKL/OPG mRNA expression in differentiating murine primary osteoblasts. 2001 J. Endocrinol. pmid:11479141
Allan GF et al. Induction of the progesterone receptor gene in estrogen target cells monitored by branched DNA signal amplification. 2001 Steroids pmid:11546554
Feige U Osteoprotegerin. 2001 Ann. Rheum. Dis. pmid:11890662
Dhore CR et al. Differential expression of bone matrix regulatory proteins in human atherosclerotic plaques. 2001 Arterioscler. Thromb. Vasc. Biol. pmid:11742876
Ramalho AC et al. Effect of oestradiol on cytokine production in immortalized human marrow stromal cell lines. 2001 Cytokine pmid:11792122
Yano K et al. Synovial cells from a patient with rheumatoid arthritis produce osteoclastogenesis inhibitory factor/osteoprotegerin: reciprocal regulation of the production by inflammatory cytokines and basic fibroblast growth factor. 2001 J. Bone Miner. Metab. pmid:11685652
Kawahara N et al. Two novel cucurbitacins, neocucurbitacins A and B, from the Brazilian folk medicine "Buchinha" (Luffa operculata) and their effect on PEBP2alphaA and OCIF gene expression in a human osteoblast-like Saos-2 cell line. 2001 Chem. Pharm. Bull. pmid:11605678
Boissy P et al. RANKL induces formation of avian osteoclasts from macrophages but not from macrophage polykaryons. 2001 Biochem. Biophys. Res. Commun. pmid:11606048
Wise GE et al. Effects of dexamethasone on tooth eruption in rats: differences in incisor and molar eruption. 2001 Clin Anat pmid:11301468
Atkins GJ et al. Osteoprotegerin inhibits osteoclast formation and bone resorbing activity in giant cell tumors of bone. 2001 Bone pmid:11336917
Komine M et al. Tumor necrosis factor-alpha cooperates with receptor activator of nuclear factor kappaB ligand in generation of osteoclasts in stromal cell-depleted rat bone marrow cell culture. 2001 Bone pmid:11344046
Chen D et al. ELISA methodology for detection of modified osteoprotegerin in clinical studies. 2001 Clin. Chem. pmid:11274028
Collin-Osdoby P et al. Receptor activator of NF-kappa B and osteoprotegerin expression by human microvascular endothelial cells, regulation by inflammatory cytokines, and role in human osteoclastogenesis. 2001 J. Biol. Chem. pmid:11274143
Brown JM et al. Osteoprotegerin and rank ligand expression in prostate cancer. 2001 Urology pmid:11306358
Fukagawa M et al. [PTH and bone metabolism in chronic dialysis patients]. 2001 Rinsho Byori pmid:11307321
Horowitz MC et al. Control of osteoclastogenesis and bone resorption by members of the TNF family of receptors and ligands. 2001 Cytokine Growth Factor Rev. pmid:11312114
Lin DL et al. Bone metastatic LNCaP-derivative C4-2B prostate cancer cell line mineralizes in vitro. 2001 Prostate pmid:11351351
Sparks AB et al. Mutation screening of the TNFRSF11A gene encoding receptor activator of NF kappa B (RANK) in familial and sporadic Paget's disease of bone and osteosarcoma. 2001 Calcif. Tissue Int. pmid:11351498
Yan T et al. Regulation of osteoclastogenesis and RANK expression by TGF-beta1. 2001 Aug 1-9 J. Cell. Biochem. pmid:11573248
Rosa-Rañal M et al. [New paradigms in the regulation of bone metabolism]. 2001 Jul-Aug Rev. Invest. Clin. pmid:11599485
Sakata M et al. Osteoprotegerin levels increased by interleukin-1beta in human periodontal ligament cells are suppressed through prostaglandin E(2) synthesized de novo. 2002 Cytokine pmid:12126649
Petersson M et al. Oxytocin stimulates proliferation of human osteoblast-like cells. 2002 Peptides pmid:12126740
Cundy T et al. A mutation in the gene TNFRSF11B encoding osteoprotegerin causes an idiopathic hyperphosphatasia phenotype. 2002 Hum. Mol. Genet. pmid:12189164
Williamson E et al. Regulation of mucosal dendritic cell function by receptor activator of NF-kappa B (RANK)/RANK ligand interactions: impact on tolerance induction. 2002 J. Immunol. pmid:12244151
Lee SK et al. 1,25(OH)2 vitamin D3-stimulated osteoclast formation in spleen-osteoblast cocultures is mediated in part by enhanced IL-1 alpha and receptor activator of NF-kappa B ligand production in osteoblasts. 2002 J. Immunol. pmid:12193704
Chen XW et al. Isoflavones regulate interleukin-6 and osteoprotegerin synthesis during osteoblast cell differentiation via an estrogen-receptor-dependent pathway. 2002 Biochem. Biophys. Res. Commun. pmid:12150965
Katagiri T and Takahashi N Regulatory mechanisms of osteoblast and osteoclast differentiation. 2002 Oral Dis pmid:12108759
Li X et al. Effects of prostaglandin E2 on gene expression in primary osteoblastic cells from prostaglandin receptor knockout mice. 2002 Bone pmid:11934647
Jiang Y et al. Bacteria induce osteoclastogenesis via an osteoblast-independent pathway. 2002 Infect. Immun. pmid:12011008
Granchi D et al. Bone cement extracts modulate the osteoprotegerin/osteoprotegerin-ligand expression in MG63 osteoblast-like cells. 2002 Biomaterials pmid:12013183
Li X et al. Prostaglandin receptor EP2 mediates PGE2 stimulated hypercalcemia in mice in vivo. 2002 Prostaglandins Other Lipid Mediat. pmid:12013525
Bosshart H Expression of survival receptors in Hodgkin disease cell lines. 2002 Blood pmid:12001908
Ono K et al. Involvement of cyclo-oxygenase-2 in osteoclast formation and bone destruction in bone metastasis of mammary carcinoma cell lines. 2002 J. Bone Miner. Res. pmid:12009007
Palenzuela L et al. Familial expansile osteolysis in a large Spanish kindred resulting from an insertion mutation in the TNFRSF11A gene. 2002 J. Med. Genet. pmid:12362049
Fu Q et al. Parathyroid hormone stimulates receptor activator of NFkappa B ligand and inhibits osteoprotegerin expression via protein kinase A activation of cAMP-response element-binding protein. 2002 J. Biol. Chem. pmid:12364326
Rogers A et al. Circulating estradiol and osteoprotegerin as determinants of bone turnover and bone density in postmenopausal women. 2002 J. Clin. Endocrinol. Metab. pmid:12364420
Romas E et al. Osteoprotegerin reduces osteoclast numbers and prevents bone erosion in collagen-induced arthritis. 2002 Am. J. Pathol. pmid:12368214
Standal T et al. Osteoprotegerin is bound, internalized, and degraded by multiple myeloma cells. 2002 Blood pmid:12351414
Sandor M et al. A novel polyethylene depot device for the study of PLGA and P(FASA) microspheres in vitro and in vivo. 2002 Biomaterials pmid:12219832
Shiotani A et al. Regulation of osteoclast differentiation and function by receptor activator of NFkB ligand and osteoprotegerin. 2002 Anat. Rec. pmid:12221720
Cremer I et al. Long-lived immature dendritic cells mediated by TRANCE-RANK interaction. 2002 Blood pmid:12393586
Giuliani N et al. Human myeloma cells stimulate the receptor activator of nuclear factor-kappa B ligand (RANKL) in T lymphocytes: a potential role in multiple myeloma bone disease. 2002 Blood pmid:12393684
Liao EY et al. Comparison of the effects of 17beta-E2 and progesterone on the expression of osteoprotegerin in normal human osteoblast-like cells. 2002 J. Endocrinol. Invest. pmid:12398237
Kazama JJ et al. Circulating osteoprotegerin is not removed through haemodialysis membrane. 2002 Nephrol. Dial. Transplant. pmid:12271009
Roux S et al. RANK (receptor activator of nuclear factor-kappaB) and RANKL expression in multiple myeloma. 2002 Br. J. Haematol. pmid:11918537
Lee SW et al. TAK1-dependent activation of AP-1 and c-Jun N-terminal kinase by receptor activator of NF-kappaB. 2002 J. Biochem. Mol. Biol. pmid:12296995
Oshiro T et al. Osteoclast induction in periodontal tissue during experimental movement of incisors in osteoprotegerin-deficient mice. 2002 Anat. Rec. pmid:11920384
Redlich K et al. Tumor necrosis factor alpha-mediated joint destruction is inhibited by targeting osteoclasts with osteoprotegerin. 2002 Arthritis Rheum. pmid:11920416
Bengtsson AK and Ryan EJ Immune function of the decoy receptor osteoprotegerin. 2002 Crit. Rev. Immunol. pmid:12498383

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