7-octadecynoic acid

7-octadecynoic acid is a lipid of Fatty Acyls (FA) class.

Cross Reference

There are no associated biomedical information in the current reference collection.

Current reference collection contains 19785 references associated with 7-octadecynoic acid in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.


Here are additional resources we collected from PubChem and MeSH for 7-octadecynoic acid

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 7-octadecynoic acid

MeSH term MeSH ID Detail
Jaw, Edentulous, Partially D007576 1 associated lipids
Bone Diseases, Endocrine D001849 1 associated lipids
Hyperphosphatemia D054559 1 associated lipids
Osteopetrosis D010022 1 associated lipids
Tooth Resorption D014091 1 associated lipids
Vascular Calcification D061205 1 associated lipids
Angioid Streaks D000793 1 associated lipids
Atrial Remodeling D064752 1 associated lipids
Chondroblastoma D002804 1 associated lipids
Rupture, Spontaneous D012422 1 associated lipids
Malocclusion, Angle Class I D008311 1 associated lipids
Hyperostosis D015576 1 associated lipids
Hip Dislocation D006617 1 associated lipids
Hyperparathyroidism, Primary D049950 1 associated lipids
Breast Neoplasms, Male D018567 1 associated lipids
Severe Combined Immunodeficiency D016511 1 associated lipids
Peri-Implantitis D057873 1 associated lipids
Adrenocortical Adenoma D018246 1 associated lipids
Bone Demineralization, Pathologic D018488 1 associated lipids
Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative D054438 1 associated lipids
Per page 10 20 50 100 | Total 298

All references with 7-octadecynoic acid

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Authors Title Published Journal PubMed Link
Nabipour I et al. Relationships among serum receptor of nuclear factor-kappaB ligand, osteoprotegerin, high-sensitivity C-reactive protein, and bone mineral density in postmenopausal women: osteoimmunity versus osteoinflammatory. 2009 Sep-Oct Menopause pmid:19387415
Pineda B et al. Effects of administration of hormone therapy or raloxifene on the immune system and on biochemical markers of bone remodeling. 2012 Menopause pmid:22067277
Lee HJ et al. Association between polymorphisms in leptin, leptin receptor, and β-adrenergic receptor genes and bone mineral density in postmenopausal Korean women. 2014 Menopause pmid:23760429
Prezelj J et al. Cathepsin K predicts femoral neck bone mineral density change in nonosteoporotic peri- and early postmenopausal women. 2008 Mar-Apr Menopause pmid:17882010
Kim JG et al. Changes in the serum levels of osteoprotegerin and soluble receptor activator for nuclear factor kappaB ligand after estrogen-progestogen therapy and their relationships with changes in bone mass in postmenopausal women. 2008 Mar-Apr Menopause pmid:17925661
Kim H et al. Association between Wnt signaling pathway gene polymorphisms and bone response to hormone therapy in postmenopausal Korean women. 2011 Menopause pmid:21471826
Reyes-García R et al. Effects of alendronate treatment on serum levels of osteoprotegerin and total receptor activator of nuclear factor kappaB in women with postmenopausal osteoporosis. 2010 Jan-Feb Menopause pmid:19574937
Tyagi AM et al. Formononetin reverses established osteopenia in adult ovariectomized rats. 2012 Menopause pmid:22781783
Zhang ZG et al. Therapeutic effect of aqueous extract from Ecliptae herba on bone metabolism of ovariectomized rats. 2013 Menopause pmid:23096243
McClung MR Looking for answers in all the wrong places. 2007 Jan-Feb Menopause pmid:17194959
Kim JG et al. Association between osteoprotegerin (OPG), receptor activator of nuclear factor-kappaB (RANK), and RANK ligand (RANKL) gene polymorphisms and circulating OPG, soluble RANKL levels, and bone mineral density in Korean postmenopausal women. 2007 Sep-Oct Menopause pmid:17667143
Oh ES et al. Circulating osteoprotegerin levels are associated with age, waist-to-hip ratio, serum total cholesterol, and low-density lipoprotein cholesterol levels in healthy Korean women. 2005 Metab. Clin. Exp. pmid:15562379
Nabipour I et al. Osteoprotegerin in relation to type 2 diabetes mellitus and the metabolic syndrome in postmenopausal women. 2010 Metab. Clin. Exp. pmid:19922962
Ostergård T et al. Endothelial function and biochemical vascular markers in first-degree relatives of type 2 diabetic patients: the effect of exercise training. 2006 Metab. Clin. Exp. pmid:17046554
O'Sullivan EP et al. A comparison of osteoprotegerin with adiponectin and high-sensitivity C-reactive protein (hsCRP) as a marker for insulin resistance. 2013 Metab. Clin. Exp. pmid:22841521
Siepi D et al. Preclinical vascular damage in white postmenopausal women: the relevance of osteoprotegerin. 2008 Metab. Clin. Exp. pmid:18249202
Maïmoun L et al. Peripubertal female athletes in high-impact sports show improved bone mass acquisition and bone geometry. 2013 Metab. Clin. Exp. pmid:23490587
Ashley DT et al. Similar to adiponectin, serum levels of osteoprotegerin are associated with obesity in healthy subjects. 2011 Metab. Clin. Exp. pmid:21087777
Wieczorek-Baranowska A et al. Osteocalcin and glucose metabolism in postmenopausal women subjected to aerobic training program for 8 weeks. 2012 Metab. Clin. Exp. pmid:22000586
Takemura M et al. Relationship between osteoprotegerin/osteoclastogenesis inhibitory factor concentration in synovial fluid and disease severity in individuals with osteoarthritis of the knee. 2001 Metab. Clin. Exp. pmid:11172466
Giusti M et al. Serum osteoprotegerin and soluble receptor activator of nuclear factor kappaB ligand levels in patients with a history of differentiated thyroid carcinoma: a case-controlled cohort study. 2007 Metab. Clin. Exp. pmid:17445547
Chang YH et al. Serum osteoprotegerin and tumor necrosis factor related apoptosis inducing-ligand (TRAIL) are elevated in type 2 diabetic patients with albuminuria and serum osteoprotegerin is independently associated with the severity of diabetic nephropathy. 2011 Metab. Clin. Exp. pmid:21251686
Ziegler S et al. Endurance running acutely raises plasma osteoprotegerin and lowers plasma receptor activator of nuclear factor kappa B ligand. 2005 Metab. Clin. Exp. pmid:15988704
Krause U et al. Assays of osteogenic differentiation by cultured human mesenchymal stem cells. 2011 Methods Mol. Biol. pmid:21431522
Nimmanapalli R and Bhalla K Targets in apoptosis signaling: promise of selective anticancer therapy. 2003 Methods Mol. Biol. pmid:12777745
Belibasakis GN et al. Oral biofilm challenge regulates the RANKL-OPG system in periodontal ligament and dental pulp cells. 2011 Microb. Pathog. pmid:21075196
Belibasakis GN et al. Regulation of RANKL and OPG gene expression in human gingival fibroblasts and periodontal ligament cells by Porphyromonas gingivalis: a putative role of the Arg-gingipains. 2007 Microb. Pathog. pmid:17448630
Reddi D et al. Porphyromonas gingivalis regulates the RANKL-OPG system in bone marrow stromal cells. 2008 Nov-Dec Microbes Infect. pmid:18789397
Sasaki T Differentiation and functions of osteoclasts and odontoclasts in mineralized tissue resorption. 2003 Microsc. Res. Tech. pmid:12879416
Helfrich MH Osteoclast diseases. 2003 Microsc. Res. Tech. pmid:12879419
Kobayashi-Sakamoto M et al. Role of alphav integrin in osteoprotegerin-induced endothelial cell migration and proliferation. 2008 Microvasc. Res. pmid:18656492
Aydin H et al. Effect of oxidative stress on aorta and tibia osteoprotegerin gene expression in ovariectomized rats. 2011 Minerva Endocrinol. pmid:21519319
Mirzaei K et al. Potential role of OPG/RANKL system and FokI genotypes in pathogenesis and clinical manifestations in multiple sclerosis. 2012 Minerva Med. pmid:22805623
Asanuma YF et al. Serum osteoprotegerin concentration is associated with carotid atherosclerotic plaque in patients with rheumatoid arthritis. 2013 Mod Rheumatol pmid:22584471
Tanishima S et al. Minodronic acid influences receptor activator of nuclear factor kappaB ligand expression and suppresses bone resorption by osteoclasts in rats with collagen-induced arthritis. 2007 Mod Rheumatol pmid:17564774
Wang Y et al. A theoretical model for simulating effect of parathyroid hormone on bone metabolism at cellular level. 2009 Mol Cell Biomech pmid:19496258
Zheleznyak A et al. Integrin α(v)β₃ as a PET imaging biomarker for osteoclast number in mouse models of negative and positive osteoclast regulation. 2012 Mol Imaging Biol pmid:21853370
Zhou QL et al. Polydatin possesses notable anti‑osteoporotic activity via regulation of OPG, RANKL and β‑catenin. 2016 Mol Med Rep pmid:27357904
Li J et al. Effect of gallium nitrate on the expression of osteoprotegerin and receptor activator of nuclear factor‑κB ligand in osteoblasts in vivo and in vitro. 2016 Mol Med Rep pmid:26647856
Ren H et al. Effects of intermedin on proliferation, apoptosis and the expression of OPG/RANKL/M-CSF in the MC3T3-E1 osteoblast cell line. 2015 Mol Med Rep pmid:26398911
Joo MK et al. The effect of a proton pump inhibitor on bone metabolism in ovariectomized rats. 2013 Mol Med Rep pmid:23426758
Ye M et al. Prednisone inhibits the focal adhesion kinase/receptor activator of NF-κB ligand/mitogen-activated protein kinase signaling pathway in rats with adriamycin-induced nephropathy. 2015 Mol Med Rep pmid:26459042
Ma Y et al. Effects of brucine on bone metabolism in multiple myeloma. 2012 Mol Med Rep pmid:22614932
Xu F et al. Adipocytes regulate the bone marrow microenvironment in a mouse model of obesity. 2013 Mol Med Rep pmid:23835909
Wei J et al. Effectiveness of combined salmon calcitonin and aspirin therapy for osteoporosis in ovariectomized rats. 2015 Mol Med Rep pmid:25891179
Wang XF et al. The role of the serum RANKL/OPG ratio in the healing of intertrochanteric fractures in elderly patients. 2013 Mol Med Rep pmid:23440406
Kuroyanagi G et al. Resveratrol amplifies BMP-4-stimulated osteoprotegerin synthesis via p38 MAP kinase in osteoblasts. 2015 Mol Med Rep pmid:26044505
Jia J et al. Estrogen stimulates osteoprotegerin expression via the suppression of miR-145 expression in MG-63 cells. 2017 Mol Med Rep pmid:28260003
Feng ZY et al. Osteoprotegerin promotes the proliferation of chondrocytes and affects the expression of ADAMTS-5 and TIMP-4 through MEK/ERK signaling. 2013 Mol Med Rep pmid:24126801
Pei Z et al. Effect of icariin on cell proliferation and the expression of bone resorption/formation-related markers in human periodontal ligament cells. 2013 Mol Med Rep pmid:24065204
Kainuma S et al. Regulation by AMP-activated protein kinase of PGE2-induced osteoprotegerin synthesis in osteoblasts. 2016 Mol Med Rep pmid:26935864
Qian H et al. FSH aggravates bone loss in ovariectomised rats with experimental periapical periodontitis. 2016 Mol Med Rep pmid:27510616
He M et al. Effect of glucocorticoids on osteoclast function in a mouse model of bone necrosis. 2016 Mol Med Rep pmid:27277157
Crosley LK et al. The single-nucleotide polymorphism (GPX4c718t) in the glutathione peroxidase 4 gene influences endothelial cell function: interaction with selenium and fatty acids. 2013 Mol Nutr Food Res pmid:23934705
Nash LA et al. Rooibos flavonoids, orientin and luteolin, stimulate mineralization in human osteoblasts through the Wnt pathway. 2015 Mol Nutr Food Res pmid:25488131
Sänger N et al. OPG and PgR show similar cohort specific effects as prognostic factors in ER positive breast cancer. 2014 Mol Oncol pmid:24785095
Jung YJ et al. Tannerella forsythia GroEL induces inflammatory bone resorption and synergizes with interleukin-17. 2017 Mol Oral Microbiol pmid:27484636
Watkins M et al. Osteoblast connexin43 modulates skeletal architecture by regulating both arms of bone remodeling. 2011 Mol. Biol. Cell pmid:21346198
Pritzker LB et al. The role of osteoprotegerin and tumor necrosis factor-related apoptosis-inducing ligand in human microvascular endothelial cell survival. 2004 Mol. Biol. Cell pmid:15064358
Hussien YM et al. Polymorphism in vitamin D receptor and osteoprotegerin genes in Egyptian rheumatoid arthritis patients with and without osteoporosis. 2013 Mol. Biol. Rep. pmid:23271131
Lee YH et al. Associations between osteoprotegerin polymorphisms and bone mineral density: a meta-analysis. 2010 Mol. Biol. Rep. pmid:19642016
Xiao HL et al. Oral administration activity determination of recombinant osteoprotegerin from silkworm larvae. 2007 Mol. Biotechnol. pmid:17435284
Weichhaus M et al. Osteoprotegerin in breast cancer: beyond bone remodeling. 2015 Mol. Cancer pmid:26054853
Fujita K and Janz S Attenuation of WNT signaling by DKK-1 and -2 regulates BMP2-induced osteoblast differentiation and expression of OPG, RANKL and M-CSF. 2007 Mol. Cancer pmid:17971207
Arrigoni C et al. Direct but not indirect co-culture with osteogenically differentiated human bone marrow stromal cells increases RANKL/OPG ratio in human breast cancer cells generating bone metastases. 2014 Mol. Cancer pmid:25335447
Reid PE et al. Breast cancer cells stimulate osteoprotegerin (OPG) production by endothelial cells through direct cell contact. 2009 Mol. Cancer pmid:19604388
Chung ST et al. Osteoprotegerin mediates tumor-promoting effects of Interleukin-1beta in breast cancer cells. 2017 Mol. Cancer pmid:28143606
Cao Y et al. The osterix transcription factor down-regulates interleukin-1 alpha expression in mouse osteosarcoma cells. 2008 Mol. Cancer Res. pmid:18234967
Higgs JT et al. Variants of Osteoprotegerin Lacking TRAIL Binding for Therapeutic Bone Remodeling in Osteolytic Malignancies. 2015 Mol. Cancer Res. pmid:25636966
Locklin RM et al. Selective targeting of death receptor 5 circumvents resistance of MG-63 osteosarcoma cells to TRAIL-induced apoptosis. 2007 Mol. Cancer Ther. pmid:18065493
Miller RE et al. RANK ligand inhibition plus docetaxel improves survival and reduces tumor burden in a murine model of prostate cancer bone metastasis. 2008 Mol. Cancer Ther. pmid:18606716
Rani CS and MacDougall M Dental cells express factors that regulate bone resorption. 2000 Mol. Cell Biol. Res. Commun. pmid:10860862
Yamaguchi M et al. Effect of zinc on gene expression in osteoblastic MC3T3-E1 cells: enhancement of Runx2, OPG, and regucalcin mRNA expressions. 2008 Mol. Cell. Biochem. pmid:18327666
Guo D et al. Bone morphogenetic protein 4 (BMP4) is required for migration and invasion of breast cancer. 2012 Mol. Cell. Biochem. pmid:22167620
Osorio A et al. Biochemical markers of vascular calcification in elderly hemodialysis patients. 2013 Mol. Cell. Biochem. pmid:23124853
Geoffroy V et al. High bone resorption in adult aging transgenic mice overexpressing cbfa1/runx2 in cells of the osteoblastic lineage. 2002 Mol. Cell. Biol. pmid:12167715
Mizukami J et al. Receptor activator of NF-kappaB ligand (RANKL) activates TAK1 mitogen-activated protein kinase kinase kinase through a signaling complex containing RANK, TAB2, and TRAF6. 2002 Mol. Cell. Biol. pmid:11809792
Subramaniam M et al. TIEG1 null mouse-derived osteoblasts are defective in mineralization and in support of osteoclast differentiation in vitro. 2005 Mol. Cell. Biol. pmid:15657444
Wang Y et al. LC, a novel estrone-rhein hybrid compound, concurrently stimulates osteoprotegerin and inhibits receptor activator of NF-κB ligand (RANKL) and interleukin-6 production by human osteoblastic cells. 2011 Mol. Cell. Endocrinol. pmid:21291955
Olesen M et al. No influence of OPG and its ligands, RANKL and TRAIL, on proliferation and regulation of the calcification process in primary human vascular smooth muscle cells. 2012 Mol. Cell. Endocrinol. pmid:22698523
Kühn MC et al. Adipocyte-secreted factors increase osteoblast proliferation and the OPG/RANKL ratio to influence osteoclast formation. 2012 Mol. Cell. Endocrinol. pmid:22040599
Tsubaki M et al. Bisphosphonate- and statin-induced enhancement of OPG expression and inhibition of CD9, M-CSF, and RANKL expressions via inhibition of the Ras/MEK/ERK pathway and activation of p38MAPK in mouse bone marrow stromal cell line ST2. 2012 Mol. Cell. Endocrinol. pmid:22579611
Welldon KJ et al. Calcium induces pro-anabolic effects on human primary osteoblasts associated with acquisition of mature osteocyte markers. 2013 Mol. Cell. Endocrinol. pmid:23791847
Ma Y et al. Acetylcholine affects osteocytic MLO-Y4 cells via acetylcholine receptors. 2014 Mol. Cell. Endocrinol. pmid:24508663
Oostra DR et al. Association of osteoprotegerin and bone loss after adjuvant chemotherapy in early-stage breast cancer. 2015 Mol. Cell. Endocrinol. pmid:25575458
Toffoli B et al. Osteoprotegerin induces morphological and functional alterations in mouse pancreatic islets. 2011 Mol. Cell. Endocrinol. pmid:20832449
Gutiérrez-Rojas I et al. Amylin exerts osteogenic actions with different efficacy depending on the diabetic status. 2013 Mol. Cell. Endocrinol. pmid:23178165
Shin J et al. Structure-function of the TNF receptor-like cysteine-rich domain of osteoprotegerin. 2008 Mol. Cells pmid:18443424
Kang HS et al. Receptor activator of nuclear factor-kappaB is induced by a rottlerin-sensitive and p38 MAP kinase-dependent pathway during monocyte differentiation. 2004 Mol. Cells pmid:15232218
Naranjo-Suarez S et al. Regulation of HIF-1α activity by overexpression of thioredoxin is independent of thioredoxin reductase status. 2013 Mol. Cells pmid:23912593
Wang N et al. Reduced bone turnover in mice lacking the P2Y13 receptor of ADP. 2012 Mol. Endocrinol. pmid:22108801
Spelsberg TC et al. The actions and interactions of sex steroids and growth factors/cytokines on the skeleton. 1999 Mol. Endocrinol. pmid:10379881
Dey P et al. Estrogen receptors β1 and β2 have opposing roles in regulating proliferation and bone metastasis genes in the prostate cancer cell line PC3. 2012 Mol. Endocrinol. pmid:23028063
Yamada Y et al. Association of polymorphisms of the osteoprotegerin gene with bone mineral density in Japanese women but not men. 2003 Mol. Genet. Metab. pmid:14680982
Yen ML et al. TNF-related apoptosis-inducing ligand (TRAIL) induces osteoclast differentiation from monocyte/macrophage lineage precursor cells. 2008 Mol. Immunol. pmid:18206242
Doschak MR et al. Improved bone delivery of osteoprotegerin by bisphosphonate conjugation in a rat model of osteoarthritis. 2009 Mar-Apr Mol. Pharm. pmid:19718808
Lee JH et al. Epigallocatechin-3-gallate inhibits osteoclastogenesis by down-regulating c-Fos expression and suppressing the nuclear factor-kappaB signal. 2010 Mol. Pharmacol. pmid:19828731
Lee ZH et al. Activation of c-Jun N-terminal kinase and activator protein 1 by receptor activator of nuclear factor kappaB. 2000 Mol. Pharmacol. pmid:11093794
Bolon B et al. Adenoviral delivery of osteoprotegerin ameliorates bone resorption in a mouse ovariectomy model of osteoporosis. 2001 Mol. Ther. pmid:11237676
Chanda D et al. Systemic osteoprotegerin gene therapy restores tumor-induced bone loss in a therapeutic model of breast cancer bone metastasis. 2008 Mol. Ther. pmid:18388919

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