Mackie PS et al. |
Bisphosphonates regulate cell growth and gene expression in the UMR 106-01 clonal rat osteosarcoma cell line. |
2001 |
Br. J. Cancer |
pmid:11286476
|
Hofbauer LC et al. |
Osteoprotegerin, RANK, and RANK ligand: the good, the bad, and the ugly in rheumatoid arthritis. |
2001 |
J. Rheumatol. |
pmid:11327234
|
Hofbauer LC and Heufelder AE |
The role of osteoprotegerin and receptor activator of nuclear factor kappaB ligand in the pathogenesis and treatment of rheumatoid arthritis. |
2001 |
Arthritis Rheum. |
pmid:11229454
|
Leach RJ et al. |
The genetics of Paget's disease of the bone. |
2001 |
J. Clin. Endocrinol. Metab. |
pmid:11231972
|
Luger NM et al. |
Osteoprotegerin diminishes advanced bone cancer pain. |
2001 |
Cancer Res. |
pmid:11358823
|
Haynes DR et al. |
Osteoprotegerin and receptor activator of nuclear factor kappaB ligand (RANKL) regulate osteoclast formation by cells in the human rheumatoid arthritic joint. |
2001 |
Rheumatology (Oxford) |
pmid:11426018
|
Szulc P et al. |
Osteoprotegerin serum levels in men: correlation with age, estrogen, and testosterone status. |
2001 |
J. Clin. Endocrinol. Metab. |
pmid:11443182
|
Sakiyama H et al. |
Establishment and characterization of macrophage-like cell lines expressing osteoclast-specific markers. |
2001 |
J. Bone Miner. Metab. |
pmid:11448014
|
Choi Y et al. |
Osteoclastogenesis is enhanced by activated B cells but suppressed by activated CD8(+) T cells. |
2001 |
Eur. J. Immunol. |
pmid:11449372
|
Kanzaki H et al. |
Dual regulation of osteoclast differentiation by periodontal ligament cells through RANKL stimulation and OPG inhibition. |
2001 |
J. Dent. Res. |
pmid:11379890
|
Hein GE |
[Pathophysiology of bone loss in rheumatic diseases--do bone markers help in monitoring?]. |
2001 |
Z Rheumatol |
pmid:11383046
|
Morony S et al. |
Osteoprotegerin inhibits osteolysis and decreases skeletal tumor burden in syngeneic and nude mouse models of experimental bone metastasis. |
2001 |
Cancer Res. |
pmid:11389072
|
Kim KJ et al. |
Osteoprotegerin inhibits in vitro mouse osteoclast formation induced by joint fluid from failed total hip arthroplasty. |
2001 |
J. Biomed. Mater. Res. |
pmid:11410897
|
Abu-Amer Y |
IL-4 abrogates osteoclastogenesis through STAT6-dependent inhibition of NF-kappaB. |
2001 |
J. Clin. Invest. |
pmid:11390419
|
Kon T et al. |
Expression of osteoprotegerin, receptor activator of NF-kappaB ligand (osteoprotegerin ligand) and related proinflammatory cytokines during fracture healing. |
2001 |
J. Bone Miner. Res. |
pmid:11393777
|
Fazzalari NL et al. |
The ratio of messenger RNA levels of receptor activator of nuclear factor kappaB ligand to osteoprotegerin correlates with bone remodeling indices in normal human cancellous bone but not in osteoarthritis. |
2001 |
J. Bone Miner. Res. |
pmid:11393778
|
Bekker PJ et al. |
The effect of a single dose of osteoprotegerin in postmenopausal women. |
2001 |
J. Bone Miner. Res. |
pmid:11204435
|
Kikuchi T et al. |
Gene expression of osteoclast differentiation factor is induced by lipopolysaccharide in mouse osteoblasts via Toll-like receptors. |
2001 |
J. Immunol. |
pmid:11207318
|
O'Brien EA et al. |
Osteoprotegerin is produced when prostaglandin synthesis is inhibited causing osteoclasts to detach from the surface of mouse parietal bone and attach to the endocranial membrane. |
2001 |
Bone |
pmid:11182380
|
Thirunavukkarasu K et al. |
Stimulation of osteoprotegerin (OPG) gene expression by transforming growth factor-beta (TGF-beta). Mapping of the OPG promoter region that mediates TGF-beta effects. |
2001 |
J. Biol. Chem. |
pmid:11451955
|
Yun TJ et al. |
Osteoprotegerin, a crucial regulator of bone metabolism, also regulates B cell development and function. |
2001 |
J. Immunol. |
pmid:11160187
|
Stejskal D et al. |
Osteoprotegerin, RANK, RANKL. |
2001 |
Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub |
pmid:12426773
|
Stejskal D et al. |
Osteoprotegerin and bone density. |
2001 |
Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub |
pmid:12426776
|
Takemura M et al. |
Relationship between osteoprotegerin/osteoclastogenesis inhibitory factor concentration in synovial fluid and disease severity in individuals with osteoarthritis of the knee. |
2001 |
Metab. Clin. Exp. |
pmid:11172466
|
Gravallese EM et al. |
The role of TNF-receptor family members and other TRAF-dependent receptors in bone resorption. |
2001 |
Arthritis Res. |
pmid:11178122
|
Makiishi-Shimobayashi C et al. |
Interleukin-18 up-regulates osteoprotegerin expression in stromal/osteoblastic cells. |
2001 |
Biochem. Biophys. Res. Commun. |
pmid:11181055
|
Lories RJ and Luyten FP |
Osteoprotegerin and osteoprotegerin-ligand balance: a new paradigm in bone metabolism providing new therapeutic targets. |
2001 |
Clin. Rheumatol. |
pmid:11254237
|
Wan M et al. |
Transcriptional mechanisms of bone morphogenetic protein-induced osteoprotegrin gene expression. |
2001 |
J. Biol. Chem. |
pmid:11139569
|
Lean JM et al. |
FLT3 ligand can substitute for macrophage colony-stimulating factor in support of osteoclast differentiation and function. |
2001 |
Blood |
pmid:11675341
|
Fiumara P et al. |
Functional expression of receptor activator of nuclear factor kappaB in Hodgkin disease cell lines. |
2001 |
Blood |
pmid:11675352
|
Satoh K et al. |
Tumor necrosis factor-related apoptosis-inducing ligand and its receptor expression and the pathway of apoptosis in human pancreatic cancer. |
2001 |
Pancreas |
pmid:11590320
|
Yano K et al. |
Immunological study on circulating murine osteoprotegerin/osteoclastogenesis inhibitory factor (OPG/OCIF): possible role of OPG/OCIF in the prevention of osteoporosis in pregnancy. |
2001 |
Biochem. Biophys. Res. Commun. |
pmid:11594776
|
Brown JM et al. |
Serum osteoprotegerin levels are increased in patients with advanced prostate cancer. |
2001 |
Clin. Cancer Res. |
pmid:11595685
|
Price PA et al. |
Osteoprotegerin inhibits artery calcification induced by warfarin and by vitamin D. |
2001 |
Arterioscler. Thromb. Vasc. Biol. |
pmid:11597934
|
Nemec K and Schubert-Zsilavecz M |
[Future therapies for metabolic bone diseases. New concepts and targets]. |
2001 |
Pharm Unserer Zeit |
pmid:11715689
|
Kuntz KA et al. |
An immunohistochemical study of osteoprotegerin in the human dental pulp. |
2001 |
J Endod |
pmid:11716077
|
Hofbauer LC and Schoppet M |
Serum measurement of osteoprotegerin--clinical relevance and potential applications. |
2001 |
Eur. J. Endocrinol. |
pmid:11720890
|
Ueland T et al. |
Increased serum osteoprotegerin in disorders characterized by persistent immune activation or glucocorticoid excess--possible role in bone homeostasis. |
2001 |
Eur. J. Endocrinol. |
pmid:11720891
|
Chikazu D et al. |
Regulation of osteoclast differentiation by fibroblast growth factor 2: stimulation of receptor activator of nuclear factor kappaB ligand/osteoclast differentiation factor expression in osteoblasts and inhibition of macrophage colony-stimulating factor function in osteoclast precursors. |
2001 |
J. Bone Miner. Res. |
pmid:11697804
|
Khosla S |
Minireview: the OPG/RANKL/RANK system. |
2001 |
Endocrinology |
pmid:11713196
|
Seidel C et al. |
Serum osteoprotegerin levels are reduced in patients with multiple myeloma with lytic bone disease. |
2001 |
Blood |
pmid:11568016
|
Fukagawa M et al. |
Skeletal resistance to pth as a basic abnormality underlying uremic bone diseases. |
2001 |
Am. J. Kidney Dis. |
pmid:11576943
|
Sato T et al. |
Osteoprotegerin levels before and after renal transplantation. |
2001 |
Am. J. Kidney Dis. |
pmid:11576949
|
Feuerherm AJ et al. |
Elevated levels of osteoprotegerin (OPG) and hepatocyte growth factor (HGF) in rheumatoid arthritis. |
2001 |
Scand. J. Rheumatol. |
pmid:11578019
|
Sakai E et al. |
Characterization of phagosomal subpopulations along endocytic routes in osteoclasts and macrophages. |
2001 |
J. Biochem. |
pmid:11726283
|
Burguera B et al. |
Leptin reduces ovariectomy-induced bone loss in rats. |
2001 |
Endocrinology |
pmid:11459801
|
Yamagishi T et al. |
Reciprocal control of expression of mRNAs for osteoclast differentiation factor and OPG in osteogenic stromal cells by genistein: evidence for the involvement of topoisomerase II in osteoclastogenesis. |
2001 |
Endocrinology |
pmid:11459812
|
Ma YL et al. |
Catabolic effects of continuous human PTH (1--38) in vivo is associated with sustained stimulation of RANKL and inhibition of osteoprotegerin and gene-associated bone formation. |
2001 |
Endocrinology |
pmid:11517184
|
Bateman TA et al. |
Osteoprotegerin ameliorates sciatic nerve crush induced bone loss. |
2001 |
J. Orthop. Res. |
pmid:11518255
|
Myoung H et al. |
Effects of a bisphosphonate on the expression of bone specific genes after autogenous free bone grafting in rats. |
2001 |
J. Periodont. Res. |
pmid:11519698
|
Haynes DR et al. |
The osteoclastogenic molecules RANKL and RANK are associated with periprosthetic osteolysis. |
2001 |
J Bone Joint Surg Br |
pmid:11521937
|
Hofbauer LC and Schoppet M |
Osteoprotegerin: a link between osteoporosis and arterial calcification? |
2001 |
Lancet |
pmid:11498208
|
Sakai A et al. |
1alpha-Hydroxyvitamin D3 suppresses trabecular bone resorption by inhibiting osteoclastogenic potential in bone marrow cells after ovariectomy in mice. |
2001 |
J. Bone Miner. Metab. |
pmid:11498729
|
Ikeda T et al. |
Expression profiles of receptor activator of nuclear factor kappaB ligand, receptor activator of nuclear factor kappaB, and osteoprotegerin messenger RNA in aged and ovariectomized rat bones. |
2001 |
J. Bone Miner. Res. |
pmid:11499864
|
Thomas GP et al. |
Changing RANKL/OPG mRNA expression in differentiating murine primary osteoblasts. |
2001 |
J. Endocrinol. |
pmid:11479141
|
Allan GF et al. |
Induction of the progesterone receptor gene in estrogen target cells monitored by branched DNA signal amplification. |
2001 |
Steroids |
pmid:11546554
|
Feige U |
Osteoprotegerin. |
2001 |
Ann. Rheum. Dis. |
pmid:11890662
|
Chung H et al. |
Deflazacort increases osteoclast formation in mouse bone marrow culture and the ratio of RANKL/OPG mRNA expression in marrow stromal cells. |
2001 |
J. Korean Med. Sci. |
pmid:11748360
|
Komuro H et al. |
The osteoprotegerin/receptor activator of nuclear factor kappaB/receptor activator of nuclear factor kappaB ligand system in cartilage. |
2001 |
Arthritis Rheum. |
pmid:11762937
|
Lindberg MK et al. |
Estrogen receptor alpha, but not estrogen receptor beta, is involved in the regulation of the OPG/RANKL (osteoprotegerin/receptor activator of NF-kappa B ligand) ratio and serum interleukin-6 in male mice. |
2001 |
J. Endocrinol. |
pmid:11739008
|
Giuliani N et al. |
Myeloma cells induce imbalance in the osteoprotegerin/osteoprotegerin ligand system in the human bone marrow environment. |
2001 |
Blood |
pmid:11739153
|
Croucher PI et al. |
Osteoprotegerin inhibits the development of osteolytic bone disease in multiple myeloma. |
2001 |
Blood |
pmid:11739154
|
Dhore CR et al. |
Differential expression of bone matrix regulatory proteins in human atherosclerotic plaques. |
2001 |
Arterioscler. Thromb. Vasc. Biol. |
pmid:11742876
|
Ramalho AC et al. |
Effect of oestradiol on cytokine production in immortalized human marrow stromal cell lines. |
2001 |
Cytokine |
pmid:11792122
|
Yano K et al. |
Synovial cells from a patient with rheumatoid arthritis produce osteoclastogenesis inhibitory factor/osteoprotegerin: reciprocal regulation of the production by inflammatory cytokines and basic fibroblast growth factor. |
2001 |
J. Bone Miner. Metab. |
pmid:11685652
|
Kawahara N et al. |
Two novel cucurbitacins, neocucurbitacins A and B, from the Brazilian folk medicine "Buchinha" (Luffa operculata) and their effect on PEBP2alphaA and OCIF gene expression in a human osteoblast-like Saos-2 cell line. |
2001 |
Chem. Pharm. Bull. |
pmid:11605678
|
Boissy P et al. |
RANKL induces formation of avian osteoclasts from macrophages but not from macrophage polykaryons. |
2001 |
Biochem. Biophys. Res. Commun. |
pmid:11606048
|
Wise GE et al. |
Effects of dexamethasone on tooth eruption in rats: differences in incisor and molar eruption. |
2001 |
Clin Anat |
pmid:11301468
|
Atkins GJ et al. |
Osteoprotegerin inhibits osteoclast formation and bone resorbing activity in giant cell tumors of bone. |
2001 |
Bone |
pmid:11336917
|
Yan T et al. |
Regulation of osteoclastogenesis and RANK expression by TGF-beta1. |
2001 Aug 1-9 |
J. Cell. Biochem. |
pmid:11573248
|
Rosa-Rañal M et al. |
[New paradigms in the regulation of bone metabolism]. |
2001 Jul-Aug |
Rev. Invest. Clin. |
pmid:11599485
|
Geoffroy V et al. |
High bone resorption in adult aging transgenic mice overexpressing cbfa1/runx2 in cells of the osteoblastic lineage. |
2002 |
Mol. Cell. Biol. |
pmid:12167715
|
Uemura H et al. |
Serum osteoprotegerin/osteoclastogenesis-inhibitory factor during pregnancy and lactation and the relationship with calcium-regulating hormones and bone turnover markers. |
2002 |
J. Endocrinol. |
pmid:12176675
|
Ragab AA et al. |
Cytokines synergistically induce osteoclast differentiation: support by immortalized or normal calvarial cells. |
2002 |
Am. J. Physiol., Cell Physiol. |
pmid:12176725
|
Whyte MP et al. |
Osteoprotegerin deficiency and juvenile Paget's disease. |
2002 |
N. Engl. J. Med. |
pmid:12124406
|
Inoue D and Matsumoto T |
[Recent advances in basic research of bone metabolism]. |
2002 |
Nippon Rinsho |
pmid:11979916
|
Suzuki Y et al. |
[Bone destruction and bone loss in rheumatoid arthritis--mechanism, prevention and treatment]. |
2002 |
Nippon Rinsho |
pmid:11979937
|
Inoue D |
[Recent advances in research of bone resorption]. |
2002 |
Nippon Rinsho |
pmid:11979946
|
Udagawa N and Takahashi N |
[Possible role of receptor activator of NF-kappa B ligand(RANKL) in osteoclast differentiation and function]. |
2002 |
Nippon Rinsho |
pmid:11979968
|
Tsuda E |
[Osteoclastogenesis inhibitory factor (OCIF)/OPG (a novel therapeutic candidate for the treatment of metabolic bone diseases)]. |
2002 |
Nippon Rinsho |
pmid:11979969
|
Fu M et al. |
Activation of peroxisome proliferator-activated receptor gamma inhibits osteoprotegerin gene expression in human aortic smooth muscle cells. |
2002 |
Biochem. Biophys. Res. Commun. |
pmid:12056809
|
Kim YH et al. |
Inhibitory action of bisphosphonates on bone resorption does not involve the regulation of RANKL and OPG expression. |
2002 |
Exp. Mol. Med. |
pmid:12085990
|
Khosla S et al. |
Correlates of osteoprotegerin levels in women and men. |
2002 |
Osteoporos Int |
pmid:12086350
|
Ueland T et al. |
Effects of 12 months of GH treatment on cortical and trabecular bone content of IGFs and OPG in adults with acquired GH deficiency: a double-blind, randomized, placebo-controlled study. |
2002 |
J. Clin. Endocrinol. Metab. |
pmid:12050246
|
Sasaki N et al. |
Changes in osteoprotegerin and markers of bone metabolism during glucocorticoid treatment in patients with chronic glomerulonephritis. |
2002 |
Bone |
pmid:12052453
|
Kudo O et al. |
Proinflammatory cytokine (TNFalpha/IL-1alpha) induction of human osteoclast formation. |
2002 |
J. Pathol. |
pmid:12237882
|
Hofbauer LC et al. |
High bone density due to a mutation in LDL-receptor-related protein 5. |
2002 |
N. Engl. J. Med. |
pmid:12240686
|
Okada Y et al. |
Cell-to-Cell adhesion via intercellular adhesion molecule-1 and leukocyte function-associated antigen-1 pathway is involved in 1alpha,25(OH)2D3, PTH and IL-1alpha-induced osteoclast differentiation and bone resorption. |
2002 |
Endocr. J. |
pmid:12402981
|
Roodman GD |
Role of the bone marrow microenvironment in multiple myeloma. |
2002 |
J. Bone Miner. Res. |
pmid:12412796
|
Ito S et al. |
Crystal structure of the extracellular domain of mouse RANK ligand at 2.2-A resolution. |
2002 |
J. Biol. Chem. |
pmid:11733492
|
Buckley KA and Fraser WD |
Receptor activator for nuclear factor kappaB ligand and osteoprotegerin: regulators of bone physiology and immune responses/potential therapeutic agents and biochemical markers. |
2002 |
Ann. Clin. Biochem. |
pmid:12564836
|
Viereck V et al. |
Bisphosphonates pamidronate and zoledronic acid stimulate osteoprotegerin production by primary human osteoblasts. |
2002 |
Biochem. Biophys. Res. Commun. |
pmid:11855844
|
Romas E et al. |
Involvement of receptor activator of NFkappaB ligand and tumor necrosis factor-alpha in bone destruction in rheumatoid arthritis. |
2002 |
Bone |
pmid:11856640
|
Viereck V et al. |
Phytoestrogen genistein stimulates the production of osteoprotegerin by human trabecular osteoblasts. |
2002 |
J. Cell. Biochem. |
pmid:11835398
|
Wise GE et al. |
Inhibition of osteoclastogenesis by the secretion of osteoprotegerin in vitro by rat dental follicle cells and its implications for tooth eruption. |
2002 |
Arch. Oral Biol. |
pmid:11839361
|
Faucheux C et al. |
Nuclear localization of type I parathyroid hormone/parathyroid hormone-related protein receptors in deer antler osteoclasts: evidence for parathyroid hormone-related protein and receptor activator of NF-kappaB-dependent effects on osteoclast formation in regenerating mammalian bone. |
2002 |
J. Bone Miner. Res. |
pmid:11874237
|
Bolon B et al. |
Duration of bone protection by a single osteoprotegerin injection in rats with adjuvant-induced arthritis. |
2002 |
Cell. Mol. Life Sci. |
pmid:12440777
|
David JP et al. |
JNK1 modulates osteoclastogenesis through both c-Jun phosphorylation-dependent and -independent mechanisms. |
2002 |
J. Cell. Sci. |
pmid:12376563
|
Jones DH et al. |
Role of RANKL and RANK in bone loss and arthritis. |
2002 |
Ann. Rheum. Dis. |
pmid:12379618
|
Gravallese EM |
Bone destruction in arthritis. |
2002 |
Ann. Rheum. Dis. |
pmid:12379632
|