7-octadecynoic acid

7-octadecynoic acid is a lipid of Fatty Acyls (FA) class.

Cross Reference

There are no associated biomedical information in the current reference collection.

Current reference collection contains 19785 references associated with 7-octadecynoic acid in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.


Here are additional resources we collected from PubChem and MeSH for 7-octadecynoic acid

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 7-octadecynoic acid

MeSH term MeSH ID Detail
Vestibulocochlear Nerve Diseases D000160 1 associated lipids
Acromegaly D000172 6 associated lipids
Actinobacillus Infections D000189 4 associated lipids
Actinomycosis D000196 2 associated lipids
Addison Disease D000224 3 associated lipids
Adenocarcinoma D000230 166 associated lipids
Adrenal Hyperplasia, Congenital D000312 2 associated lipids
Albuminuria D000419 18 associated lipids
Alzheimer Disease D000544 76 associated lipids
Angina, Unstable D000789 14 associated lipids
Per page 10 20 50 100 | Total 298

All references with 7-octadecynoic acid

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Authors Title Published Journal PubMed Link
Qiang YW et al. Myeloma-derived Dickkopf-1 disrupts Wnt-regulated osteoprotegerin and RANKL production by osteoblasts: a potential mechanism underlying osteolytic bone lesions in multiple myeloma. 2008 Blood pmid:18305214
Sauer AV et al. ADA-deficient SCID is associated with a specific microenvironment and bone phenotype characterized by RANKL/OPG imbalance and osteoblast insufficiency. 2009 Blood pmid:19633200
Chagraoui H et al. Stimulation of osteoprotegerin production is responsible for osteosclerosis in mice overexpressing TPO. 2003 Blood pmid:12506018
Kastritis E et al. Osteoprotegerin is a significant prognostic factor for overall survival in patients with primary systemic amyloidosis independent of the Mayo staging. 2015 Blood Cancer J pmid:26047389
Nihrane A et al. Depletion of the Shwachman-Diamond syndrome gene product, SBDS, leads to growth inhibition and increased expression of OPG and VEGF-A. 2009 Jan-Feb Blood Cells Mol. Dis. pmid:19014892
Brändström H et al. A single nucleotide polymorphism in the promoter region of the osteoprotegerin gene is related to intima-media thickness of the carotid artery in hypertensive patients. The Swedish Irbesartan Left Ventricular Hypertrophy Investigation vs Atenolol (SILVHIA). 2004 Blood Press. pmid:15223723
Tsirpanlis G Is inflammation the link between atherosclerosis and vascular calcification in chronic kidney disease? 2007 Blood Purif. pmid:17261926
Cianciolo G et al. Coronary calcifications in end-stage renal disease patients: a new link between osteoprotegerin, diabetes and body mass index? 2010 Blood Purif. pmid:19816015
Cozzolino M Emerging roles for osteoprotegerin and receptor activator of nuclear factor-kappaB in the vascular system. 2009 Blood Purif. pmid:19729903
Lee JH et al. Tumor necrosis factor-α converting enzyme (TACE) increases RANKL expression in osteoblasts and serves as a potential biomarker of periodontitis. 2011 BMB Rep pmid:21777519
Narita N et al. A genetic polymorphism of the osteoprotegerin gene is associated with an increased risk of advanced prostate cancer. 2008 BMC Cancer pmid:18684318
Goswami S and Sharma-Walia N Osteoprotegerin secreted by inflammatory and invasive breast cancer cells induces aneuploidy, cell proliferation and angiogenesis. 2015 BMC Cancer pmid:26608463
Ney JT et al. Genetic polymorphism of the OPG gene associated with breast cancer. 2013 BMC Cancer pmid:23369128
Niu Y et al. Association of plasma osteoprotegerin levels with the severity of lower extremity arterial disease in patients with type 2 diabetes. 2015 BMC Cardiovasc Disord pmid:26260869
Sponder M et al. Endurance training significantly increases serum endocan but not osteoprotegerin levels: a prospective observational study. 2017 BMC Cardiovasc Disord pmid:28056805
Nagy EE et al. High circulating osteoprotegerin levels are associated with non-zero blood groups. 2016 BMC Cardiovasc Disord pmid:27387019
Liu M et al. Semen Astragali Complanati- and Rhizoma Cibotii-enhanced bone formation in osteoporosis rats. 2013 BMC Complement Altern Med pmid:23782721
Fathilah SN et al. Labisia pumila regulates bone-related genes expressions in postmenopausal osteoporosis model. 2013 BMC Complement Altern Med pmid:24007208
Wei CC et al. Total glucosides of paeony prevents juxta-articular bone loss in experimental arthritis. 2013 BMC Complement Altern Med pmid:23870279
Shen Y et al. (5R)-5-Hydroxytriptolide (LLDT-8) inhibits osteoclastogenesis via RANKL/RANK/OPG signaling pathway. 2015 BMC Complement Altern Med pmid:25887296
Shuid AN et al. Eurycoma longifolia upregulates osteoprotegerin gene expression in androgen- deficient osteoporosis rat model. 2012 BMC Complement Altern Med pmid:22967165
Niu Y et al. Association of osteoprotegerin with impaired glucose regulation and microalbuminuria: the REACTION study. 2015 BMC Endocr Disord pmid:26626139
Fortner RT et al. Osteoprotegerin and breast cancer risk by hormone receptor subtype: a nested case-control study in the EPIC cohort. 2017 BMC Med pmid:28173834
Piedra M et al. "Single nucleotide polymorphisms of the OPG/RANKL system genes in primary hyperparathyroidism and their relationship with bone mineral density". 2011 BMC Med. Genet. pmid:22185226
Kulcsar-Jakab E et al. Cystatin C as a potential predictor of osteoprotegerin levels in healthy men, a cross-sectional, observational study. 2015 BMC Musculoskelet Disord pmid:26311162
Kauther MD et al. Calcitonin substitution in calcitonin deficiency reduces particle-induced osteolysis. 2011 BMC Musculoskelet Disord pmid:21843355
Kim CH et al. Effects of high frequency loading on RANKL and OPG mRNA expression in ST-2 murine stromal cells. 2009 BMC Musculoskelet Disord pmid:19728893
Evans CE et al. Age of donor alters the effect of cyclic hydrostatic pressure on production by human macrophages and osteoblasts of sRANKL, OPG and RANK. 2006 BMC Musculoskelet Disord pmid:16519799
Lv Y et al. Effects of pamidronate disodium on the loss of osteoarthritic subchondral bone and the expression of cartilaginous and subchondral osteoprotegerin and RANKL in rabbits. 2014 BMC Musculoskelet Disord pmid:25377946
Ma J et al. Up-regulation of multiple proteins and biological processes during maxillary expansion in rats. 2008 BMC Musculoskelet Disord pmid:18366685
Zhou DA et al. Influence of glucocorticoids on the osteogenic differentiation of rat bone marrow-derived mesenchymal stem cells. 2014 BMC Musculoskelet Disord pmid:25027542
Taylan A et al. Biomarkers and cytokines of bone turnover: extensive evaluation in a cohort of patients with ankylosing spondylitis. 2012 BMC Musculoskelet Disord pmid:23025387
Pateinakis P et al. Associations of fetuin-A and osteoprotegerin with arterial stiffness and early atherosclerosis in chronic hemodialysis patients. 2013 BMC Nephrol pmid:23758931
Janda K et al. Cardiovascular risk in chronic kidney disease patients: intima-media thickness predicts the incidence and severity of histologically assessed medial calcification in radial arteries. 2015 BMC Nephrol pmid:26037625
Rzepka R et al. Soluble receptors for advanced glycation end products and receptor activator of NF-κB ligand serum levels as markers of premature labor. 2015 BMC Pregnancy Childbirth pmid:26059227
Jiang H et al. A randomized controlled trial of pre-conception treatment for periodontal disease to improve periodontal status during pregnancy and birth outcomes. 2013 BMC Pregnancy Childbirth pmid:24321402
Duan P et al. Gene polymorphisms in RANKL/RANK/OPG pathway are associated with ages at menarche and natural menopause in Chinese women. 2015 BMC Womens Health pmid:25884698
Pivonka P et al. Model structure and control of bone remodeling: a theoretical study. 2008 Bone pmid:18514606
Asaba Y et al. Urinary gamma-glutamyltransferase (GGT) as a potential marker of bone resorption. 2006 Bone pmid:16942925
O'Connor RD et al. Mecp2 deficiency decreases bone formation and reduces bone volume in a rodent model of Rett syndrome. 2009 Bone pmid:19414073
O'Brien EA et al. Osteoprotegerin is produced when prostaglandin synthesis is inhibited causing osteoclasts to detach from the surface of mouse parietal bone and attach to the endocranial membrane. 2001 Bone pmid:11182380
Bendre MS et al. Interleukin-8 stimulation of osteoclastogenesis and bone resorption is a mechanism for the increased osteolysis of metastatic bone disease. 2003 Bone pmid:12919697
Bi Y et al. Biglycan deficiency increases osteoclast differentiation and activity due to defective osteoblasts. 2006 Bone pmid:16364709
Ralston SH Pathogenesis of Paget's disease of bone. 2008 Bone pmid:18672105
Bateman TA et al. Osteoprotegerin mitigates tail suspension-induced osteopenia. 2000 Bone pmid:10773583
Canon J et al. Inhibition of RANKL increases the anti-tumor effect of the EGFR inhibitor panitumumab in a murine model of bone metastasis. 2010 Bone pmid:20215062
Verdrengh M et al. RANKL-targeted therapy inhibits bone resorption in experimental Staphylococcus aureus-induced arthritis. 2010 Bone pmid:19879986
Zhang Y et al. Differential mRNA expression profiles in proximal tibia of aged rats in response to ovariectomy and low-Ca diet. 2009 Bone pmid:18848653
Gruber R et al. Platelet-released supernatants stimulate formation of osteoclast-like cells through a prostaglandin/RANKL-dependent mechanism. 2002 Bone pmid:11996911
Proposed standard nomenclature for new tumor necrosis factor members involved in the regulation of bone resorption. The American Society for Bone and Mineral Research President's Committee on Nomenclature. 2000 Bone pmid:11113385
Silva HC et al. Higher prevalence of morphometric vertebral fractures in patients with recent coronary events independently of BMD measurements. 2013 Bone pmid:23142805
Kanematsu M et al. Vector-averaged gravity regulates gene expression of receptor activator of NF-kappaB (RANK) ligand and osteoprotegerin in bone marrow stromal cells via cyclic AMP/protein kinase A pathway. 2002 Bone pmid:11934645
Li X et al. Effects of prostaglandin E2 on gene expression in primary osteoblastic cells from prostaglandin receptor knockout mice. 2002 Bone pmid:11934647
Seriwatanachai D et al. Prolactin directly enhances bone turnover by raising osteoblast-expressed receptor activator of nuclear factor kappaB ligand/osteoprotegerin ratio. 2008 Bone pmid:18166509
Vanella L et al. HO-1 expression increases mesenchymal stem cell-derived osteoblasts but decreases adipocyte lineage. 2010 Bone pmid:19853072
Ueland T et al. No associations between OPG gene polymorphisms or serum levels and measures of osteoporosis in elderly Australian women. 2007 Bone pmid:16949901
Walker CG et al. Osteopontin is required for unloading-induced osteoclast recruitment and modulation of RANKL expression during tooth drift-associated bone remodeling, but not for super-eruption. 2010 Bone pmid:20828639
El-Hoss J et al. Modulation of endochondral ossification by MEK inhibitors PD0325901 and AZD6244 (Selumetinib). 2014 Bone pmid:24269278
Zheng Y et al. Inhibition of bone resorption, rather than direct cytotoxicity, mediates the anti-tumour actions of ibandronate and osteoprotegerin in a murine model of breast cancer bone metastasis. 2007 Bone pmid:17092788
Sasaki N et al. Changes in osteoprotegerin and markers of bone metabolism during glucocorticoid treatment in patients with chronic glomerulonephritis. 2002 Bone pmid:12052453
Peng S et al. The cross-talk between osteoclasts and osteoblasts in response to strontium treatment: involvement of osteoprotegerin. 2011 Bone pmid:21925296
Xu M et al. Basal bone phenotype and increased anabolic responses to intermittent parathyroid hormone in healthy male COX-2 knockout mice. 2010 Bone pmid:20471507
Zheng D et al. The beneficial effect of Icariin on bone is diminished in osteoprotegerin-deficient mice. 2012 Bone pmid:22551876
Uemura H et al. Circulating osteoprotegerin in women during GnRH-agonist treatment and their relationships with mineral components and biomarkers of bone turnover. 2003 Bone pmid:14623063
Liu J et al. Comparison of the effects of genistein and zoledronic acid on the bone loss in OPG-deficient mice. 2008 Bone pmid:18337202
Ostrowska Z et al. RANKL/RANK/OPG system and bone status in females with anorexia nervosa. 2012 Bone pmid:22001124
Saidenberg-Kermanac'h N et al. TNF-alpha antibodies and osteoprotegerin decrease systemic bone loss associated with inflammation through distinct mechanisms in collagen-induced arthritis. 2004 Bone pmid:15542046
Ho TY et al. Effects of relaxin and estrogens on bone remodeling markers, receptor activator of NF-kB ligand (RANKL) and osteoprotegerin (OPG), in rat adjuvant-induced arthritis. 2011 Bone pmid:21419242
Ueland T et al. Growth hormone substitution increases gene expression of members of the IGF family in cortical bone from women with adult onset growth hormone deficiency--relationship with bone turn-over. 2003 Bone pmid:14555269
Nagata N et al. Inhibition of RANKL-induced osteoclast formation in mouse bone marrow cells by IL-12: involvement of IFN-gamma possibly induced from non-T cell population. 2003 Bone pmid:14555278
LaCroix AZ et al. OPG and sRANKL serum levels and incident hip fracture in postmenopausal Caucasian women in the Women's Health Initiative Observational Study. 2013 Bone pmid:23735608
Bord S et al. The effects of estrogen on osteoprotegerin, RANKL, and estrogen receptor expression in human osteoblasts. 2003 Bone pmid:12633785
Reginster JY et al. Strontium ranelate treatment increases osteoprotegerin serum levels in postmenopausal osteoporotic women. 2012 Bone pmid:22270053
Wada N et al. Lipopolysaccharide stimulates expression of osteoprotegerin and receptor activator of NF-kappa B ligand in periodontal ligament fibroblasts through the induction of interleukin-1 beta and tumor necrosis factor-alpha. 2004 Bone pmid:15336598
Kacena MA et al. Megakaryocyte-mediated inhibition of osteoclast development. 2006 Bone pmid:16782418
Bataille C et al. Different sympathetic pathways control the metabolism of distinct bone envelopes. 2012 Bone pmid:22326888
Wuyts W et al. Evaluation of the role of RANK and OPG genes in Paget's disease of bone. 2001 Bone pmid:11165949
Ren W et al. Effect of oral erythromycin therapy in patients with aseptic loosening of joint prostheses. 2009 Bone pmid:19154802
Liang QQ et al. The expression of osteoprotegerin is required for maintaining the intervertebral disc endplate of aged mice. 2011 Bone pmid:21466864
Kiviranta R et al. Impaired bone resorption in cathepsin K-deficient mice is partially compensated for by enhanced osteoclastogenesis and increased expression of other proteases via an increased RANKL/OPG ratio. 2005 Bone pmid:15664014
Mulcahy LE et al. RANKL and OPG activity is regulated by injury size in networks of osteocyte-like cells. 2011 Bone pmid:20854946
Aspenberg P et al. Targeting RANKL for reduction of bone loss around unstable implants: OPG-Fc compared to alendronate in a model for mechanically induced loosening. 2011 Bone pmid:20858557
Mossetti G et al. Interleukin-6 and osteoprotegerin systems in Paget's disease of bone: relationship to risedronate treatment. 2005 Bone pmid:15777635
Janssens K et al. An intermediate form of juvenile Paget's disease caused by a truncating TNFRSF11B mutation. 2005 Bone pmid:15777670
Valenta A et al. Combined treatment with PTH (1-34) and OPG increases bone volume and uniformity of mineralization in aged ovariectomized rats. 2005 Bone pmid:15869920
Fukushima H et al. IL-1-induced receptor activator of NF-kappa B ligand in human periodontal ligament cells involves ERK-dependent PGE2 production. 2005 Bone pmid:15780952
Regmi A et al. Suramin interacts with RANK and inhibits RANKL-induced osteoclast differentiation. 2005 Bone pmid:15780954
Irie A et al. Heparin enhances osteoclastic bone resorption by inhibiting osteoprotegerin activity. 2007 Bone pmid:17560185
Abrahamsen B et al. Circulating amounts of osteoprotegerin and RANK ligand: genetic influence and relationship with BMD assessed in female twins. 2005 Bone pmid:15781001
Dunn MD et al. Local delivery of osteoprotegerin inhibits mechanically mediated bone modeling in orthodontic tooth movement. 2007 Bone pmid:17588510
Balga R et al. Tumor necrosis factor-alpha: alternative role as an inhibitor of osteoclast formation in vitro. 2006 Bone pmid:16580896
Bord S et al. Megakaryocytes modulate osteoblast synthesis of type-l collagen, osteoprotegerin, and RANKL. 2005 Bone pmid:15794927
Dimitri P et al. Adipokines, bone-derived factors and bone turnover in obese children; evidence for altered fat-bone signalling resulting in reduced bone mass. 2011 Bone pmid:20932948
Ulrich-Vinther M et al. Gene therapy with human osteoprotegerin decreases callus remodeling with limited effects on biomechanical properties. 2005 Bone pmid:16169783
Romas E et al. Involvement of receptor activator of NFkappaB ligand and tumor necrosis factor-alpha in bone destruction in rheumatoid arthritis. 2002 Bone pmid:11856640
Fahrleitner A et al. Serum osteoprotegerin is a major determinant of bone density development and prevalent vertebral fracture status following cardiac transplantation. 2003 Bone pmid:12584041
Buckley KA et al. Adenosine triphosphate stimulates human osteoclast activity via upregulation of osteoblast-expressed receptor activator of nuclear factor-kappa B ligand. 2002 Bone pmid:12477572
Atkins GJ et al. Osteoprotegerin inhibits osteoclast formation and bone resorbing activity in giant cell tumors of bone. 2001 Bone pmid:11336917
Komine M et al. Tumor necrosis factor-alpha cooperates with receptor activator of nuclear factor kappaB ligand in generation of osteoclasts in stromal cell-depleted rat bone marrow cell culture. 2001 Bone pmid:11344046
Mori K et al. DU145 human prostate cancer cells express functional receptor activator of NFkappaB: new insights in the prostate cancer bone metastasis process. 2007 Bone pmid:17196895

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