7-octadecynoic acid

7-octadecynoic acid is a lipid of Fatty Acyls (FA) class.

Cross Reference

There are no associated biomedical information in the current reference collection.

Current reference collection contains 19785 references associated with 7-octadecynoic acid in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.


Here are additional resources we collected from PubChem and MeSH for 7-octadecynoic acid

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 7-octadecynoic acid

MeSH term MeSH ID Detail
Vestibulocochlear Nerve Diseases D000160 1 associated lipids
Acromegaly D000172 6 associated lipids
Actinobacillus Infections D000189 4 associated lipids
Actinomycosis D000196 2 associated lipids
Addison Disease D000224 3 associated lipids
Adenocarcinoma D000230 166 associated lipids
Adrenal Hyperplasia, Congenital D000312 2 associated lipids
Albuminuria D000419 18 associated lipids
Alzheimer Disease D000544 76 associated lipids
Angina, Unstable D000789 14 associated lipids
Per page 10 20 50 100 | Total 298

All references with 7-octadecynoic acid

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Authors Title Published Journal PubMed Link
Mandelin J et al. Human osteoblasts produce cathepsin K. 2006 Bone pmid:16337236
You L et al. Osteocytes as mechanosensors in the inhibition of bone resorption due to mechanical loading. 2008 Bone pmid:17997378
Bi Y et al. Biglycan deficiency increases osteoclast differentiation and activity due to defective osteoblasts. 2006 Bone pmid:16364709
García-Hernández A et al. High glucose concentrations alter the biomineralization process in human osteoblastic cells. 2012 Bone pmid:22086137
Bougioukli S et al. Combination therapy with BMP-2 and a systemic RANKL inhibitor enhances bone healing in a mouse critical-sized femoral defect. 2016 Bone pmid:26723577
West SL et al. The effect of exercise and estrogen on osteoprotegerin in premenopausal women. 2009 Bone pmid:18929691
Bateman TA et al. Osteoprotegerin mitigates tail suspension-induced osteopenia. 2000 Bone pmid:10773583
Seriwatanachai D et al. Prolactin directly enhances bone turnover by raising osteoblast-expressed receptor activator of nuclear factor kappaB ligand/osteoprotegerin ratio. 2008 Bone pmid:18166509
Vanella L et al. HO-1 expression increases mesenchymal stem cell-derived osteoblasts but decreases adipocyte lineage. 2010 Bone pmid:19853072
Walker CG et al. Osteopontin is required for unloading-induced osteoclast recruitment and modulation of RANKL expression during tooth drift-associated bone remodeling, but not for super-eruption. 2010 Bone pmid:20828639
Sato M et al. New 19-nor-(20S)-1alpha,25-dihydroxyvitamin D3 analogs strongly stimulate osteoclast formation both in vivo and in vitro. 2007 Bone pmid:17070129
Zheng Y et al. Inhibition of bone resorption, rather than direct cytotoxicity, mediates the anti-tumour actions of ibandronate and osteoprotegerin in a murine model of breast cancer bone metastasis. 2007 Bone pmid:17092788
Peng S et al. The cross-talk between osteoclasts and osteoblasts in response to strontium treatment: involvement of osteoprotegerin. 2011 Bone pmid:21925296
Khoshniat S et al. Phosphate-dependent stimulation of MGP and OPN expression in osteoblasts via the ERK1/2 pathway is modulated by calcium. 2011 Bone pmid:21147284
Zheng D et al. The beneficial effect of Icariin on bone is diminished in osteoprotegerin-deficient mice. 2012 Bone pmid:22551876
Liu J et al. Comparison of the effects of genistein and zoledronic acid on the bone loss in OPG-deficient mice. 2008 Bone pmid:18337202
Buijs JT et al. Inhibition of bone resorption and growth of breast cancer in the bone microenvironment. 2009 Bone pmid:19041433
Kido S et al. Expression of RANK is dependent upon differentiation into the macrophage/osteoclast lineage: induction by 1alpha,25-dihydroxyvitamin D3 and TPA in a human myelomonocytic cell line, HL60. 2003 Bone pmid:12810169
Ho TY et al. Effects of relaxin and estrogens on bone remodeling markers, receptor activator of NF-kB ligand (RANKL) and osteoprotegerin (OPG), in rat adjuvant-induced arthritis. 2011 Bone pmid:21419242
Kudlacek S et al. Serum levels of osteoprotegerin increase with age in a healthy adult population. 2003 Bone pmid:12810175
Yasuda H et al. A novel molecular mechanism modulating osteoclast differentiation and function. 1999 Bone pmid:10423033
Ueland T et al. Growth hormone substitution increases gene expression of members of the IGF family in cortical bone from women with adult onset growth hormone deficiency--relationship with bone turn-over. 2003 Bone pmid:14555269
Nagata N et al. Inhibition of RANKL-induced osteoclast formation in mouse bone marrow cells by IL-12: involvement of IFN-gamma possibly induced from non-T cell population. 2003 Bone pmid:14555278
LaCroix AZ et al. OPG and sRANKL serum levels and incident hip fracture in postmenopausal Caucasian women in the Women's Health Initiative Observational Study. 2013 Bone pmid:23735608
Bord S et al. The effects of estrogen on osteoprotegerin, RANKL, and estrogen receptor expression in human osteoblasts. 2003 Bone pmid:12633785
Reginster JY et al. Strontium ranelate treatment increases osteoprotegerin serum levels in postmenopausal osteoporotic women. 2012 Bone pmid:22270053
Kacena MA et al. Megakaryocyte-mediated inhibition of osteoclast development. 2006 Bone pmid:16782418
Wuyts W et al. Evaluation of the role of RANK and OPG genes in Paget's disease of bone. 2001 Bone pmid:11165949
Ren W et al. Effect of oral erythromycin therapy in patients with aseptic loosening of joint prostheses. 2009 Bone pmid:19154802
Naot D et al. Molecular mechanisms involved in the mitogenic effect of lactoferrin in osteoblasts. 2011 Bone pmid:21515435
Matsuzaki E et al. Sphingosine-1-phosphate promotes the nuclear translocation of β-catenin and thereby induces osteoprotegerin gene expression in osteoblast-like cell lines. 2013 Bone pmid:23612487
Liang QQ et al. The expression of osteoprotegerin is required for maintaining the intervertebral disc endplate of aged mice. 2011 Bone pmid:21466864
Mossetti G et al. Interleukin-6 and osteoprotegerin systems in Paget's disease of bone: relationship to risedronate treatment. 2005 Bone pmid:15777635
Janssens K et al. An intermediate form of juvenile Paget's disease caused by a truncating TNFRSF11B mutation. 2005 Bone pmid:15777670
Fukushima H et al. IL-1-induced receptor activator of NF-kappa B ligand in human periodontal ligament cells involves ERK-dependent PGE2 production. 2005 Bone pmid:15780952
Regmi A et al. Suramin interacts with RANK and inhibits RANKL-induced osteoclast differentiation. 2005 Bone pmid:15780954
Irie A et al. Heparin enhances osteoclastic bone resorption by inhibiting osteoprotegerin activity. 2007 Bone pmid:17560185
Dimitri P et al. Adipokines, bone-derived factors and bone turnover in obese children; evidence for altered fat-bone signalling resulting in reduced bone mass. 2011 Bone pmid:20932948
Shahnazari M et al. Bone turnover markers in peripheral blood and marrow plasma reflect trabecular bone loss but not endocortical expansion in aging mice. 2012 Bone pmid:22154841
Ulrich-Vinther M et al. Gene therapy with human osteoprotegerin decreases callus remodeling with limited effects on biomechanical properties. 2005 Bone pmid:16169783
Buckley KA et al. Adenosine triphosphate stimulates human osteoclast activity via upregulation of osteoblast-expressed receptor activator of nuclear factor-kappa B ligand. 2002 Bone pmid:12477572
Baek KH et al. Changes in the serum sex steroids, IL-7 and RANKL-OPG system after bone marrow transplantation: influences on bone and mineral metabolism. 2006 Bone pmid:16905375
Mori K et al. DU145 human prostate cancer cells express functional receptor activator of NFkappaB: new insights in the prostate cancer bone metastasis process. 2007 Bone pmid:17196895
Tanaka M et al. Alteration of Dickkopf-1 and receptor activator of nuclear factor-κB ligand during PBSC mobilization in healthy donors by G-CSF. 2012 Bone Marrow Transplant. pmid:22120987
Estanislau IM et al. Pleiotropic effects of statins on the treatment of chronic periodontitis--a systematic review. 2015 Br J Clin Pharmacol pmid:25444240
Mackie PS et al. Bisphosphonates regulate cell growth and gene expression in the UMR 106-01 clonal rat osteosarcoma cell line. 2001 Br. J. Cancer pmid:11286476
Beuselinck B et al. RANK/OPG ratio of expression in primary clear-cell renal cell carcinoma is associated with bone metastasis and prognosis in patients treated with anti-VEGFR-TKIs. 2015 Br. J. Cancer pmid:26528707
Lau YS et al. Malignant melanoma and bone resorption. 2006 Br. J. Cancer pmid:16641914
Lau YS et al. Cellular and humoral mechanisms of osteoclast formation in Ewing's sarcoma. 2007 Br. J. Cancer pmid:17533390
Pepe J et al. Lumbar bone mineral density as the major factor determining increased prevalence of vertebral fractures in monoclonal gammopathy of undetermined significance. 2006 Br. J. Haematol. pmid:16848794
Haaber J et al. Myeloma cell expression of 10 candidate genes for osteolytic bone disease. Only overexpression of DKK1 correlates with clinical bone involvement at diagnosis. 2008 Br. J. Haematol. pmid:18005268
Magal I et al. Serum levels of osteoprotegerin and osteoprotegerin polymorphisms in Gaucher disease. 2006 Br. J. Haematol. pmid:16512834
Shalhoub V et al. Characterization of osteoclast precursors in human blood. 2000 Br. J. Haematol. pmid:11122091
Terpos E et al. New insights into the pathophysiology and management of bone disease in multiple myeloma. 2003 Br. J. Haematol. pmid:14632767
Chollet ME et al. Evidence of a colocalisation of osteoprotegerin (OPG) with von Willebrand factor (VWF) in platelets and megakaryocytes alpha granules. Studies from normal and grey platelets. 2010 Br. J. Haematol. pmid:19958354
Terpos E et al. Bortezomib reduces serum dickkopf-1 and receptor activator of nuclear factor-kappaB ligand concentrations and normalises indices of bone remodelling in patients with relapsed multiple myeloma. 2006 Br. J. Haematol. pmid:17107351
Voskaridou E et al. Pamidronate is an effective treatment for osteoporosis in patients with beta-thalassaemia. 2003 Br. J. Haematol. pmid:14616979
Politou M et al. Role of receptor activator of nuclear factor-kappa B ligand (RANKL), osteoprotegerin and macrophage protein 1-alpha (MIP-1a) in monoclonal gammopathy of undetermined significance (MGUS). 2004 Br. J. Haematol. pmid:15327520
Depil S et al. Evaluation and prognostic value of serum osteoprotegerin in multiple myeloma. 2005 Br. J. Haematol. pmid:15916694
Bord S et al. Synthesis of osteoprotegerin and RANKL by megakaryocytes is modulated by oestrogen. 2004 Br. J. Haematol. pmid:15238146
Roux S et al. RANK (receptor activator of nuclear factor-kappaB) and RANKL expression in multiple myeloma. 2002 Br. J. Haematol. pmid:11918537
Bock O et al. Osteosclerosis in advanced chronic idiopathic myelofibrosis is associated with endothelial overexpression of osteoprotegerin. 2005 Br. J. Haematol. pmid:15982347
Chen WF et al. Total flavonoid fraction of the Herba epimedii extract suppresses urinary calcium excretion and improves bone properties in ovariectomised mice. 2011 Br. J. Nutr. pmid:20815976
Zhao H et al. Long-term resveratrol treatment prevents ovariectomy-induced osteopenia in rats without hyperplastic effects on the uterus. 2014 Br. J. Nutr. pmid:24073920
Karieb S and Fox SW Zinc modifies the effect of phyto-oestrogens on osteoblast and osteoclast differentiation in vitro. 2012 Br. J. Nutr. pmid:22289672
Zhang Y et al. Erythrina variegata extract exerts osteoprotective effects by suppression of the process of bone resorption. 2010 Br. J. Nutr. pmid:20487580
Hooshmand S et al. The effect of dried plum on serum levels of receptor activator of NF-κB ligand, osteoprotegerin and sclerostin in osteopenic postmenopausal women: a randomised controlled trial. 2014 Br. J. Nutr. pmid:24780728
Chen WF and Wong MS Genistein modulates the effects of parathyroid hormone in human osteoblastic SaOS-2 cells. 2006 Br. J. Nutr. pmid:16768824
Wong KC et al. Drynaria fortunei-derived total flavonoid fraction and isolated compounds exert oestrogen-like protective effects in bone. 2013 Br. J. Nutr. pmid:23302510
Mok SK et al. Icariin protects against bone loss induced by oestrogen deficiency and activates oestrogen receptor-dependent osteoblastic functions in UMR 106 cells. 2010 Br. J. Pharmacol. pmid:20128811
Brennan TC et al. Osteoblasts play key roles in the mechanisms of action of strontium ranelate. 2009 Br. J. Pharmacol. pmid:19563530
Michael H et al. Differential effects of selective oestrogen receptor modulators (SERMs) tamoxifen, ospemifene and raloxifene on human osteoclasts in vitro. 2007 Br. J. Pharmacol. pmid:17420779
Liu W et al. Polymorphisms in three genes are associated with hemorrhagic stroke. 2015 Brain Behav pmid:26664786
Petri AD et al. Effects of low-level laser therapy on human osteoblastic cells grown on titanium. 2010 Braz Dent J pmid:21271038
Tera Tde M et al. The RANK/ RANKL/ OPG interaction in the repair of autogenous bone grafts in female rats with estrogen deficiency. 2014 Braz Oral Res pmid:25229791
Zhang L et al. Effects of IL-10 and glucose on expression of OPG and RANKL in human periodontal ligament fibroblasts. 2016 Braz. J. Med. Biol. Res. pmid:27074164
Taveira AT et al. Longitudinal evaluation of hepatic osteodystrophy in children and adolescents with chronic cholestatic liver disease. 2010 Braz. J. Med. Biol. Res. pmid:21049245
Nascimento MM et al. Elevated levels of plasma osteoprotegerin are associated with all-cause mortality risk and atherosclerosis in patients with stages 3 to 5 chronic kidney disease. 2014 Braz. J. Med. Biol. Res. pmid:25296363
Bezerra MC et al. RANK, RANKL and osteoprotegerin in arthritic bone loss. 2005 Braz. J. Med. Biol. Res. pmid:15785827
Mariúba MV et al. Effect of triiodothyronine on the maxilla and masseter muscles of the rat stomatognathic system. 2011 Braz. J. Med. Biol. Res. pmid:21584440
Rachner TD et al. Dickkopf-1 is regulated by the mevalonate pathway in breast cancer. 2014 Breast Cancer Res. pmid:24528599
Canon J et al. RANKL inhibition combined with tamoxifen treatment increases anti-tumor efficacy and prevents tumor-induced bone destruction in an estrogen receptor-positive breast cancer bone metastasis model. 2012 Breast Cancer Res. Treat. pmid:22926264
Holen I et al. Osteoprotegerin (OPG) expression by breast cancer cells in vitro and breast tumours in vivo--a role in tumour cell survival? 2005 Breast Cancer Res. Treat. pmid:16155791
Jacot W et al. Increased prevalence of vitamin D insufficiency in patients with breast cancer after neoadjuvant chemotherapy. 2012 Breast Cancer Res. Treat. pmid:22562178
Neville-Webbe HL et al. Osteoprotegerin (OPG) produced by bone marrow stromal cells protects breast cancer cells from TRAIL-induced apoptosis. 2004 Breast Cancer Res. Treat. pmid:15567943
Bénard J [From metastatic osteolysis a painful message: beginning to understand with osteoprotegerin? 2000 Bull Cancer pmid:11184451
Clézardin P [The role of RANK/RANKL/osteoprotegerin (OPG) triad in cancer-induced bone diseases: physiopathology and clinical implications]. 2011 Bull Cancer pmid:21700551
Sawajiri M et al. Different effects of carbon ion and gamma-irradiation on expression of receptor activator of NF-kB ligand in MC3T3-E1 osteoblast cells. 2006 Bull. Exp. Biol. Med. pmid:17415477
Callaci JJ et al. Binge alcohol-induced bone damage is accompanied by differential expression of bone remodeling-related genes in rat vertebral bone. 2009 Calcif. Tissue Int. pmid:19330277
Bae YJ and Kim MH Calcium and Magnesium Supplementation Improves Serum OPG/RANKL in Calcium-Deficient Ovariectomized Rats. 2010 Calcif. Tissue Int. pmid:20811796
Rendina D et al. Bone turnover and the osteoprotegerin-RANKL pathway in tumor-induced osteomalacia: a longitudinal study of five cases. 2009 Calcif. Tissue Int. pmid:19763378
Brändström H et al. Single nucleotide polymorphisms in the human gene for osteoprotegerin are not related to bone mineral density or fracture in elderly women. 2004 Calcif. Tissue Int. pmid:14508625
Valero C et al. Osteoprotegerin and bone mass in squamous cell head and neck cancer patients. 2006 Calcif. Tissue Int. pmid:16830204
Brabnikova Maresova K et al. Acute effects of glucocorticoids on serum markers of osteoclasts, osteoblasts, and osteocytes. 2013 Calcif. Tissue Int. pmid:23247536
de Souza Faloni AP et al. Jaw and long bone marrows have a different osteoclastogenic potential. 2011 Calcif. Tissue Int. pmid:20862464
Dong SS et al. Association analyses of RANKL/RANK/OPG gene polymorphisms with femoral neck compression strength index variation in Caucasians. 2009 Calcif. Tissue Int. pmid:19458885
Varga F et al. Triiodothyronine (T3) and 1,25-dihydroxyvitamin D3 (1,25D3) inversely regulate OPG gene expression in dependence of the osteoblastic phenotype. 2004 Calcif. Tissue Int. pmid:15255076
Tabuchi M et al. Enhancement of crude bone morphogenetic protein-induced new bone formation and normalization of endochondral ossification by bisphosphonate treatment in osteoprotegerin-deficient mice. 2005 Calcif. Tissue Int. pmid:16193235
Ichinose Y et al. Osteoclastogenesis inhibitory factor/osteoprotegerin reduced bone loss induced by mechanical unloading. 2004 Calcif. Tissue Int. pmid:15549649
Rude RK et al. Magnesium deficiency: effect on bone and mineral metabolism in the mouse. 2003 Calcif. Tissue Int. pmid:12370796

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