Luger NM et al. |
Osteoprotegerin diminishes advanced bone cancer pain. |
2001 |
Cancer Res. |
pmid:11358823
|
Haynes DR et al. |
Osteoprotegerin and receptor activator of nuclear factor kappaB ligand (RANKL) regulate osteoclast formation by cells in the human rheumatoid arthritic joint. |
2001 |
Rheumatology (Oxford) |
pmid:11426018
|
Szulc P et al. |
Osteoprotegerin serum levels in men: correlation with age, estrogen, and testosterone status. |
2001 |
J. Clin. Endocrinol. Metab. |
pmid:11443182
|
Sakiyama H et al. |
Establishment and characterization of macrophage-like cell lines expressing osteoclast-specific markers. |
2001 |
J. Bone Miner. Metab. |
pmid:11448014
|
Choi Y et al. |
Osteoclastogenesis is enhanced by activated B cells but suppressed by activated CD8(+) T cells. |
2001 |
Eur. J. Immunol. |
pmid:11449372
|
Kanzaki H et al. |
Dual regulation of osteoclast differentiation by periodontal ligament cells through RANKL stimulation and OPG inhibition. |
2001 |
J. Dent. Res. |
pmid:11379890
|
Hein GE |
[Pathophysiology of bone loss in rheumatic diseases--do bone markers help in monitoring?]. |
2001 |
Z Rheumatol |
pmid:11383046
|
Morony S et al. |
Osteoprotegerin inhibits osteolysis and decreases skeletal tumor burden in syngeneic and nude mouse models of experimental bone metastasis. |
2001 |
Cancer Res. |
pmid:11389072
|
Kim KJ et al. |
Osteoprotegerin inhibits in vitro mouse osteoclast formation induced by joint fluid from failed total hip arthroplasty. |
2001 |
J. Biomed. Mater. Res. |
pmid:11410897
|
Abu-Amer Y |
IL-4 abrogates osteoclastogenesis through STAT6-dependent inhibition of NF-kappaB. |
2001 |
J. Clin. Invest. |
pmid:11390419
|
Kon T et al. |
Expression of osteoprotegerin, receptor activator of NF-kappaB ligand (osteoprotegerin ligand) and related proinflammatory cytokines during fracture healing. |
2001 |
J. Bone Miner. Res. |
pmid:11393777
|
Fazzalari NL et al. |
The ratio of messenger RNA levels of receptor activator of nuclear factor kappaB ligand to osteoprotegerin correlates with bone remodeling indices in normal human cancellous bone but not in osteoarthritis. |
2001 |
J. Bone Miner. Res. |
pmid:11393778
|
Bekker PJ et al. |
The effect of a single dose of osteoprotegerin in postmenopausal women. |
2001 |
J. Bone Miner. Res. |
pmid:11204435
|
Kikuchi T et al. |
Gene expression of osteoclast differentiation factor is induced by lipopolysaccharide in mouse osteoblasts via Toll-like receptors. |
2001 |
J. Immunol. |
pmid:11207318
|
O'Brien EA et al. |
Osteoprotegerin is produced when prostaglandin synthesis is inhibited causing osteoclasts to detach from the surface of mouse parietal bone and attach to the endocranial membrane. |
2001 |
Bone |
pmid:11182380
|
Zhang YH et al. |
Tumor necrosis factor-alpha (TNF) stimulates RANKL-induced osteoclastogenesis via coupling of TNF type 1 receptor and RANK signaling pathways. |
2001 |
J. Biol. Chem. |
pmid:11032840
|
Thirunavukkarasu K et al. |
Stimulation of osteoprotegerin (OPG) gene expression by transforming growth factor-beta (TGF-beta). Mapping of the OPG promoter region that mediates TGF-beta effects. |
2001 |
J. Biol. Chem. |
pmid:11451955
|
Yun TJ et al. |
Osteoprotegerin, a crucial regulator of bone metabolism, also regulates B cell development and function. |
2001 |
J. Immunol. |
pmid:11160187
|
Stejskal D et al. |
Osteoprotegerin, RANK, RANKL. |
2001 |
Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub |
pmid:12426773
|
Stejskal D et al. |
Osteoprotegerin and bone density. |
2001 |
Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub |
pmid:12426776
|
Takemura M et al. |
Relationship between osteoprotegerin/osteoclastogenesis inhibitory factor concentration in synovial fluid and disease severity in individuals with osteoarthritis of the knee. |
2001 |
Metab. Clin. Exp. |
pmid:11172466
|
Gravallese EM et al. |
The role of TNF-receptor family members and other TRAF-dependent receptors in bone resorption. |
2001 |
Arthritis Res. |
pmid:11178122
|
Makiishi-Shimobayashi C et al. |
Interleukin-18 up-regulates osteoprotegerin expression in stromal/osteoblastic cells. |
2001 |
Biochem. Biophys. Res. Commun. |
pmid:11181055
|
Brändström H et al. |
Regulation of osteoprotegerin secretion from primary cultures of human bone marrow stromal cells. |
2001 |
Biochem. Biophys. Res. Commun. |
pmid:11162596
|
Wuyts W et al. |
Evaluation of the role of RANK and OPG genes in Paget's disease of bone. |
2001 |
Bone |
pmid:11165949
|
Michigami T et al. |
Receptor activator of nuclear factor kappaB ligand (RANKL) is a key molecule of osteoclast formation for bone metastasis in a newly developed model of human neuroblastoma. |
2001 |
Cancer Res. |
pmid:11245477
|
Wada N et al. |
Periodontal ligament cells secrete the factor that inhibits osteoclastic differentiation and function: the factor is osteoprotegerin/osteoclastogenesis inhibitory factor. |
2001 |
J. Periodont. Res. |
pmid:11246705
|
Jung K et al. |
Osteoprotegerin in serum as a novel marker of bone metastatic spread in prostate cancer. |
2001 |
Clin. Chem. |
pmid:11673385
|
Lean JM et al. |
FLT3 ligand can substitute for macrophage colony-stimulating factor in support of osteoclast differentiation and function. |
2001 |
Blood |
pmid:11675341
|
Fiumara P et al. |
Functional expression of receptor activator of nuclear factor kappaB in Hodgkin disease cell lines. |
2001 |
Blood |
pmid:11675352
|
Satoh K et al. |
Tumor necrosis factor-related apoptosis-inducing ligand and its receptor expression and the pathway of apoptosis in human pancreatic cancer. |
2001 |
Pancreas |
pmid:11590320
|
Yano K et al. |
Immunological study on circulating murine osteoprotegerin/osteoclastogenesis inhibitory factor (OPG/OCIF): possible role of OPG/OCIF in the prevention of osteoporosis in pregnancy. |
2001 |
Biochem. Biophys. Res. Commun. |
pmid:11594776
|
Brown JM et al. |
Serum osteoprotegerin levels are increased in patients with advanced prostate cancer. |
2001 |
Clin. Cancer Res. |
pmid:11595685
|
Price PA et al. |
Osteoprotegerin inhibits artery calcification induced by warfarin and by vitamin D. |
2001 |
Arterioscler. Thromb. Vasc. Biol. |
pmid:11597934
|
Nemec K and Schubert-Zsilavecz M |
[Future therapies for metabolic bone diseases. New concepts and targets]. |
2001 |
Pharm Unserer Zeit |
pmid:11715689
|
Kuntz KA et al. |
An immunohistochemical study of osteoprotegerin in the human dental pulp. |
2001 |
J Endod |
pmid:11716077
|
Hofbauer LC and Schoppet M |
Serum measurement of osteoprotegerin--clinical relevance and potential applications. |
2001 |
Eur. J. Endocrinol. |
pmid:11720890
|
Ueland T et al. |
Increased serum osteoprotegerin in disorders characterized by persistent immune activation or glucocorticoid excess--possible role in bone homeostasis. |
2001 |
Eur. J. Endocrinol. |
pmid:11720891
|
Chikazu D et al. |
Regulation of osteoclast differentiation by fibroblast growth factor 2: stimulation of receptor activator of nuclear factor kappaB ligand/osteoclast differentiation factor expression in osteoblasts and inhibition of macrophage colony-stimulating factor function in osteoclast precursors. |
2001 |
J. Bone Miner. Res. |
pmid:11697804
|
Khosla S |
Minireview: the OPG/RANKL/RANK system. |
2001 |
Endocrinology |
pmid:11713196
|
Seidel C et al. |
Serum osteoprotegerin levels are reduced in patients with multiple myeloma with lytic bone disease. |
2001 |
Blood |
pmid:11568016
|
Hocking LJ et al. |
Genomewide search in familial Paget disease of bone shows evidence of genetic heterogeneity with candidate loci on chromosomes 2q36, 10p13, and 5q35. |
2001 |
Am. J. Hum. Genet. |
pmid:11555792
|
Hofbauer LC et al. |
Receptor activator of nuclear factor-kappaB ligand and osteoprotegerin: potential implications for the pathogenesis and treatment of malignant bone diseases. |
2001 |
Cancer |
pmid:11505389
|
Hofbauer LC and Heufelder AE |
Role of receptor activator of nuclear factor-kappaB ligand and osteoprotegerin in bone cell biology. |
2001 |
J. Mol. Med. |
pmid:11485016
|
Furuya D et al. |
Immuno-PCR assay for homodimeric osteoprotegerin. |
2001 |
Clin. Chem. |
pmid:11468243
|
Seck T et al. |
Serum parathyroid hormone, but not menopausal status, is associated with the expression of osteoprotegerin and RANKL mRNA in human bone samples. |
2001 |
Eur. J. Endocrinol. |
pmid:11454517
|
Burguera B et al. |
Leptin reduces ovariectomy-induced bone loss in rats. |
2001 |
Endocrinology |
pmid:11459801
|
Yamagishi T et al. |
Reciprocal control of expression of mRNAs for osteoclast differentiation factor and OPG in osteogenic stromal cells by genistein: evidence for the involvement of topoisomerase II in osteoclastogenesis. |
2001 |
Endocrinology |
pmid:11459812
|
Ma YL et al. |
Catabolic effects of continuous human PTH (1--38) in vivo is associated with sustained stimulation of RANKL and inhibition of osteoprotegerin and gene-associated bone formation. |
2001 |
Endocrinology |
pmid:11517184
|
Bateman TA et al. |
Osteoprotegerin ameliorates sciatic nerve crush induced bone loss. |
2001 |
J. Orthop. Res. |
pmid:11518255
|
Myoung H et al. |
Effects of a bisphosphonate on the expression of bone specific genes after autogenous free bone grafting in rats. |
2001 |
J. Periodont. Res. |
pmid:11519698
|
Haynes DR et al. |
The osteoclastogenic molecules RANKL and RANK are associated with periprosthetic osteolysis. |
2001 |
J Bone Joint Surg Br |
pmid:11521937
|
Hofbauer LC and Schoppet M |
Osteoprotegerin: a link between osteoporosis and arterial calcification? |
2001 |
Lancet |
pmid:11498208
|
Sakai A et al. |
1alpha-Hydroxyvitamin D3 suppresses trabecular bone resorption by inhibiting osteoclastogenic potential in bone marrow cells after ovariectomy in mice. |
2001 |
J. Bone Miner. Metab. |
pmid:11498729
|
Ikeda T et al. |
Expression profiles of receptor activator of nuclear factor kappaB ligand, receptor activator of nuclear factor kappaB, and osteoprotegerin messenger RNA in aged and ovariectomized rat bones. |
2001 |
J. Bone Miner. Res. |
pmid:11499864
|
Thomas GP et al. |
Changing RANKL/OPG mRNA expression in differentiating murine primary osteoblasts. |
2001 |
J. Endocrinol. |
pmid:11479141
|
Allan GF et al. |
Induction of the progesterone receptor gene in estrogen target cells monitored by branched DNA signal amplification. |
2001 |
Steroids |
pmid:11546554
|
Feige U |
Osteoprotegerin. |
2001 |
Ann. Rheum. Dis. |
pmid:11890662
|
Halladay DL et al. |
Identification of signal transduction pathways and promoter sequences that mediate parathyroid hormone 1-38 inhibition of osteoprotegerin gene expression. |
2001 |
J. Cell. Biochem. |
pmid:11746511
|
Cao Y et al. |
IKKalpha provides an essential link between RANK signaling and cyclin D1 expression during mammary gland development. |
2001 |
Cell |
pmid:11747812
|
Chung H et al. |
Deflazacort increases osteoclast formation in mouse bone marrow culture and the ratio of RANKL/OPG mRNA expression in marrow stromal cells. |
2001 |
J. Korean Med. Sci. |
pmid:11748360
|
Komuro H et al. |
The osteoprotegerin/receptor activator of nuclear factor kappaB/receptor activator of nuclear factor kappaB ligand system in cartilage. |
2001 |
Arthritis Rheum. |
pmid:11762937
|
Lindberg MK et al. |
Estrogen receptor alpha, but not estrogen receptor beta, is involved in the regulation of the OPG/RANKL (osteoprotegerin/receptor activator of NF-kappa B ligand) ratio and serum interleukin-6 in male mice. |
2001 |
J. Endocrinol. |
pmid:11739008
|
Giuliani N et al. |
Myeloma cells induce imbalance in the osteoprotegerin/osteoprotegerin ligand system in the human bone marrow environment. |
2001 |
Blood |
pmid:11739153
|
Croucher PI et al. |
Osteoprotegerin inhibits the development of osteolytic bone disease in multiple myeloma. |
2001 |
Blood |
pmid:11739154
|
Dhore CR et al. |
Differential expression of bone matrix regulatory proteins in human atherosclerotic plaques. |
2001 |
Arterioscler. Thromb. Vasc. Biol. |
pmid:11742876
|
Ramalho AC et al. |
Effect of oestradiol on cytokine production in immortalized human marrow stromal cell lines. |
2001 |
Cytokine |
pmid:11792122
|
Yano K et al. |
Synovial cells from a patient with rheumatoid arthritis produce osteoclastogenesis inhibitory factor/osteoprotegerin: reciprocal regulation of the production by inflammatory cytokines and basic fibroblast growth factor. |
2001 |
J. Bone Miner. Metab. |
pmid:11685652
|
Kawahara N et al. |
Two novel cucurbitacins, neocucurbitacins A and B, from the Brazilian folk medicine "Buchinha" (Luffa operculata) and their effect on PEBP2alphaA and OCIF gene expression in a human osteoblast-like Saos-2 cell line. |
2001 |
Chem. Pharm. Bull. |
pmid:11605678
|
Yan T et al. |
Regulation of osteoclastogenesis and RANK expression by TGF-beta1. |
2001 Aug 1-9 |
J. Cell. Biochem. |
pmid:11573248
|
Rosa-Rañal M et al. |
[New paradigms in the regulation of bone metabolism]. |
2001 Jul-Aug |
Rev. Invest. Clin. |
pmid:11599485
|
Whyte MP et al. |
Osteoprotegerin deficiency and juvenile Paget's disease. |
2002 |
N. Engl. J. Med. |
pmid:12124406
|
Krane SM |
Genetic control of bone remodeling--insights from a rare disease. |
2002 |
N. Engl. J. Med. |
pmid:12124412
|
Ziolkowska M et al. |
High levels of osteoprotegerin and soluble receptor activator of nuclear factor kappa B ligand in serum of rheumatoid arthritis patients and their normalization after anti-tumor necrosis factor alpha treatment. |
2002 |
Arthritis Rheum. |
pmid:12124857
|
Campagnuolo G et al. |
Kinetics of bone protection by recombinant osteoprotegerin therapy in Lewis rats with adjuvant arthritis. |
2002 |
Arthritis Rheum. |
pmid:12124878
|
Sakata M et al. |
Osteoprotegerin levels increased by interleukin-1beta in human periodontal ligament cells are suppressed through prostaglandin E(2) synthesized de novo. |
2002 |
Cytokine |
pmid:12126649
|
Tsuda E |
[Osteoclastogenesis inhibitory factor (OCIF)/OPG (a novel therapeutic candidate for the treatment of metabolic bone diseases)]. |
2002 |
Nippon Rinsho |
pmid:11979969
|
Koshihara Y |
[Recent progress of bone cell culture system (review)]. |
2002 |
Nippon Rinsho |
pmid:11979973
|
Khosla S et al. |
Effect of estrogen versus testosterone on circulating osteoprotegerin and other cytokine levels in normal elderly men. |
2002 |
J. Clin. Endocrinol. Metab. |
pmid:11932280
|
Kanematsu M et al. |
Vector-averaged gravity regulates gene expression of receptor activator of NF-kappaB (RANK) ligand and osteoprotegerin in bone marrow stromal cells via cyclic AMP/protein kinase A pathway. |
2002 |
Bone |
pmid:11934645
|
Li X et al. |
Effects of prostaglandin E2 on gene expression in primary osteoblastic cells from prostaglandin receptor knockout mice. |
2002 |
Bone |
pmid:11934647
|
Sasaki N et al. |
Changes in osteoprotegerin and markers of bone metabolism during glucocorticoid treatment in patients with chronic glomerulonephritis. |
2002 |
Bone |
pmid:12052453
|
Palenzuela L et al. |
Familial expansile osteolysis in a large Spanish kindred resulting from an insertion mutation in the TNFRSF11A gene. |
2002 |
J. Med. Genet. |
pmid:12362049
|
Roodman GD |
Role of the bone marrow microenvironment in multiple myeloma. |
2002 |
J. Bone Miner. Res. |
pmid:12412796
|
Hegedus D et al. |
Decreased bone density, elevated serum osteoprotegerin, and beta-cross-laps in Wilson disease. |
2002 |
J. Bone Miner. Res. |
pmid:12412803
|
Zhao S et al. |
MLO-Y4 osteocyte-like cells support osteoclast formation and activation. |
2002 |
J. Bone Miner. Res. |
pmid:12412815
|
Hu Y and Yu S |
Gene expression of osteoprotegerin and osteoclast differentiation factor in giant cell tumor. |
2002 |
Zhonghua Bing Li Xue Za Zhi |
pmid:12419159
|
Sandor M et al. |
A novel polyethylene depot device for the study of PLGA and P(FASA) microspheres in vitro and in vivo. |
2002 |
Biomaterials |
pmid:12219832
|
Ito S et al. |
Crystal structure of the extracellular domain of mouse RANK ligand at 2.2-A resolution. |
2002 |
J. Biol. Chem. |
pmid:11733492
|
Holen I et al. |
Osteoprotegerin (OPG) is a survival factor for human prostate cancer cells. |
2002 |
Cancer Res. |
pmid:11912131
|
Mori H et al. |
RANK ligand, RANK, and OPG expression in type II collagen-induced arthritis mouse. |
2002 |
Histochem. Cell Biol. |
pmid:11914926
|
Scatena M and Giachelli C |
The alpha(v)beta3 integrin, NF-kappaB, osteoprotegerin endothelial cell survival pathway. Potential role in angiogenesis. |
2002 |
Trends Cardiovasc. Med. |
pmid:11852256
|
Hofbauer LC and Kühne CA |
Cytokine inhibition: a new therapeutic avenue for skeletal diseases. |
2002 |
Drug Discov. Today |
pmid:11854049
|
Viereck V et al. |
Bisphosphonates pamidronate and zoledronic acid stimulate osteoprotegerin production by primary human osteoblasts. |
2002 |
Biochem. Biophys. Res. Commun. |
pmid:11855844
|
Whyte MP and Hughes AE |
Expansile skeletal hyperphosphatasia is caused by a 15-base pair tandem duplication in TNFRSF11A encoding RANK and is allelic to familial expansile osteolysis. |
2002 |
J. Bone Miner. Res. |
pmid:11771666
|
Gravallese EM |
Bone destruction in arthritis. |
2002 |
Ann. Rheum. Dis. |
pmid:12379632
|
Spyrou P et al. |
Cytokine release by osteoblast-like cells cultured on implant discs of varying alloy compositions. |
2002 |
Clin Oral Implants Res |
pmid:12519337
|
Berenson JR |
Advances in the biology and treatment of myeloma bone disease. |
2002 |
Semin. Oncol. |
pmid:12520479
|
Woo KM et al. |
Osteoprotegerin is present on the membrane of osteoclasts isolated from mouse long bones. |
2002 |
Exp. Mol. Med. |
pmid:12526098
|
Bengtsson AK and Ryan EJ |
Immune function of the decoy receptor osteoprotegerin. |
2002 |
Crit. Rev. Immunol. |
pmid:12498383
|