17-octadecynoic acid is a lipid of Fatty Acyls (FA) class. 17-octadecynoic acid is associated with abnormalities such as Renal tubular disorder, Hypertensive disease, abnormal fragmented structure, Blood Clot and Subarachnoid Hemorrhage. The involved functions are known as Hypoxia, Pathological Dilatation, Anabolism, Biochemical Pathway and Stimulus. 17-octadecynoic acid often locates in Endothelium, Muscle, Protoplasm, Microsomes and Membrane. The associated genes with 17-octadecynoic acid are P4HTM gene, EDNRA gene, Gene Family, IMPACT gene and PPP1R1A gene. The related lipids are 17-octadecynoic acid, Fatty Acids, 1-oleoyl-2-acetoyl-sn-glycerol and fatty acid analog.
To understand associated biological information of 17-octadecynoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
17-octadecynoic acid is suspected in Hypertensive disease, Renal tubular disorder, Blood Clot, Subarachnoid Hemorrhage, Renal vascular disorder and other diseases in descending order of the highest number of associated sentences.
| Disease | Cross reference | Weighted score | Related literature |
|---|
We collected disease MeSH terms mapped to the references associated with 17-octadecynoic acid
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Body Weight | D001835 | 333 associated lipids |
| Hyperthyroidism | D006980 | 12 associated lipids |
| Cicatrix | D002921 | 9 associated lipids |
| Glioblastoma | D005909 | 27 associated lipids |
| Corneal Neovascularization | D016510 | 8 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
|---|
| Function | Cross reference | Weighted score | Related literatures |
|---|
| Lipid concept | Cross reference | Weighted score | Related literatures |
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| Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Kunert MP et al. | Cytochrome P-450 omega-hydroxylase: a potential O(2) sensor in rat arterioles and skeletal muscle cells. | 2001 | Am. J. Physiol. Heart Circ. Physiol. | pmid:11247799 |
| Chlopicki S et al. | Initial and sustained phases of myogenic response of rat mesenteric small arteries. | 2001 | Am. J. Physiol. Heart Circ. Physiol. | pmid:11668080 |
| Hoepfl B et al. | EDHF, but not NO or prostaglandins, is critical to evoke a conducted dilation upon ACh in hamster arterioles. | 2002 | Am. J. Physiol. Heart Circ. Physiol. | pmid:12181129 |
| Kehl F et al. | 20-HETE contributes to the acute fall in cerebral blood flow after subarachnoid hemorrhage in the rat. | 2002 | Am. J. Physiol. Heart Circ. Physiol. | pmid:11893593 |
| Hatoum OA et al. | Role of hydrogen peroxide in ACh-induced dilation of human submucosal intestinal microvessels. | 2005 | Am. J. Physiol. Heart Circ. Physiol. | pmid:15345486 |
| Karamsetty MR et al. | EDHF contributes to strain-related differences in pulmonary arterial relaxation in rats. | 2001 | Am. J. Physiol. Lung Cell Mol. Physiol. | pmid:11159029 |
| Alvarez DF et al. | Role of EETs in regulation of endothelial permeability in rat lung. | 2004 | Am. J. Physiol. Lung Cell Mol. Physiol. | pmid:14578116 |
| Lee SJ et al. | Cytochrome P-450 metabolites in endothelin-stimulated cardiac hormone secretion. | 2004 | Am. J. Physiol. Regul. Integr. Comp. Physiol. | pmid:14715489 |
| Alonso-Galicia M et al. | Role of 20-hydroxyeicosatetraenoic acid in the renal and vasoconstrictor actions of angiotensin II. | 2002 | Am. J. Physiol. Regul. Integr. Comp. Physiol. | pmid:12069931 |
| Wang X et al. | Determinants of renal afferent arteriolar actions of bradykinin: evidence that multiple pathways mediate responses attributed to EDHF. | 2003 | Am. J. Physiol. Renal Physiol. | pmid:12734100 |