17-octadecynoic acid is a lipid of Fatty Acyls (FA) class. 17-octadecynoic acid is associated with abnormalities such as Renal tubular disorder, Hypertensive disease, abnormal fragmented structure, Blood Clot and Subarachnoid Hemorrhage. The involved functions are known as Hypoxia, Pathological Dilatation, Anabolism, Biochemical Pathway and Stimulus. 17-octadecynoic acid often locates in Endothelium, Muscle, Protoplasm, Microsomes and Membrane. The associated genes with 17-octadecynoic acid are P4HTM gene, EDNRA gene, Gene Family, IMPACT gene and PPP1R1A gene. The related lipids are 17-octadecynoic acid, Fatty Acids, 1-oleoyl-2-acetoyl-sn-glycerol and fatty acid analog.
To understand associated biological information of 17-octadecynoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
17-octadecynoic acid is suspected in Hypertensive disease, Renal tubular disorder, Blood Clot, Subarachnoid Hemorrhage, Renal vascular disorder and other diseases in descending order of the highest number of associated sentences.
| Disease | Cross reference | Weighted score | Related literature |
|---|
We collected disease MeSH terms mapped to the references associated with 17-octadecynoic acid
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Body Weight | D001835 | 333 associated lipids |
| Hyperthyroidism | D006980 | 12 associated lipids |
| Cicatrix | D002921 | 9 associated lipids |
| Glioblastoma | D005909 | 27 associated lipids |
| Corneal Neovascularization | D016510 | 8 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
|---|
| Function | Cross reference | Weighted score | Related literatures |
|---|
| Lipid concept | Cross reference | Weighted score | Related literatures |
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| Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Kunert MP et al. | Cytochrome P-450 omega-hydroxylase: a potential O(2) sensor in rat arterioles and skeletal muscle cells. | 2001 | Am. J. Physiol. Heart Circ. Physiol. | pmid:11247799 |
| Kohagura K et al. | Involvement of cytochrome P450 metabolites in the vascular action of angiotensin II on the afferent arterioles. | 2001 | Hypertens. Res. | pmid:11675950 |
| Grainger J and Boachie-Ansah G | Anandamide-induced relaxation of sheep coronary arteries: the role of the vascular endothelium, arachidonic acid metabolites and potassium channels. | 2001 | Br. J. Pharmacol. | pmid:11682448 |
| Chlopicki S et al. | Initial and sustained phases of myogenic response of rat mesenteric small arteries. | 2001 | Am. J. Physiol. Heart Circ. Physiol. | pmid:11668080 |
| Kunert MP et al. | Differential effect of cytochrome P-450 omega-hydroxylase inhibition on O2-induced constriction of arterioles in SHR with early and established hypertension. | 2001 | Microcirculation | pmid:11781816 |
| Edwards G et al. | Further investigations into the endothelium-dependent hyperpolarizing effects of bradykinin and substance P in porcine coronary artery. | 2001 | Br. J. Pharmacol. | pmid:11487526 |
| Hii CS et al. | Activation of the phosphatidylinositol 3-kinase-Akt/protein kinase B signaling pathway in arachidonic acid-stimulated human myeloid and endothelial cells: involvement of the ErbB receptor family. | 2001 | J. Biol. Chem. | pmid:11359783 |
| Ungvari Z and Koller A | Mediation of EDHF-induced reduction of smooth muscle [Ca(2+)](i) and arteriolar dilation by K(+) channels, 5,6-EET, and gap junctions. | 2001 | Microcirculation | pmid:11528534 |
| Frisbee JC et al. | Role of prostanoids and 20-HETE in mediating oxygen-induced constriction of skeletal muscle resistance arteries. | 2001 | Microvasc. Res. | pmid:11678630 |
| Alexander LD et al. | Arachidonic acid directly activates members of the mitogen-activated protein kinase superfamily in rabbit proximal tubule cells. | 2001 | Kidney Int. | pmid:11380805 |