MeSH term | MeSH ID | Detail |
---|---|---|
Hemolysis | D006461 | 131 associated lipids |
Arrhythmias, Cardiac | D001145 | 42 associated lipids |
Diabetes Mellitus, Type 1 | D003922 | 56 associated lipids |
1-Palmitoyl-sn-glycero-3-phosphocholine is a lipid of Glycerophospholipids (GP) class. 1-palmitoyl-sn-glycero-3-phosphocholine is associated with abnormalities such as Intrahepatic Cholestasis and Dysentery, Shigella dysenteriae. The involved functions are known as Homeostasis, Signal Transduction, Saturated, mRNA Expression and Synthesis. 1-palmitoyl-sn-glycero-3-phosphocholine often locates in Hepatic. The associated genes with 1-Palmitoyl-sn-glycero-3-phosphocholine are PPARA gene, TGFBR2 gene, SMAD3 gene and PLA2G6 gene. The related lipids are Fatty Acids, palmitoyl lysophosphatidylcholine, LYSO-PC and 1-palmitoyl-2-hydroxy-sn-glycero-3-phosphocholine.
To understand associated biological information of 1-Palmitoyl-sn-glycero-3-phosphocholine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
1-Palmitoyl-sn-glycero-3-phosphocholine is suspected in Intrahepatic Cholestasis, Dysentery, Shigella dysenteriae and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with 1-Palmitoyl-sn-glycero-3-phosphocholine
MeSH term | MeSH ID | Detail |
---|---|---|
Hemolysis | D006461 | 131 associated lipids |
Arrhythmias, Cardiac | D001145 | 42 associated lipids |
Diabetes Mellitus, Type 1 | D003922 | 56 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
Lipid concept | Cross reference | Weighted score | Related literatures |
---|
Gene | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Alonso A et al. | Lipids favoring inverted phase enhance the ability of aerolysin to permeabilize liposome bilayers. | 2000 | Biochemistry | pmid:11087349 |
Shi A et al. | Lysophosphatidylcholine molecular species in low density lipoprotein and high density lipoprotein in alloxan-induced diabetic rats: effect of probucol. | 1999 | Exp. Clin. Endocrinol. Diabetes | pmid:10543409 |
Grossmann G et al. | Experimental neonatal respiratory failure induced by lysophosphatidylcholine: effect of surfactant treatment. | 1999 | J. Appl. Physiol. | pmid:9931201 |
Arbibe L et al. | Generation of lyso-phospholipids from surfactant in acute lung injury is mediated by type-II phospholipase A2 and inhibited by a direct surfactant protein A-phospholipase A2 protein interaction. | 1998 | J. Clin. Invest. | pmid:9739049 |
Wenk MR and Seelig J | Proton induced vesicle fusion and the isothermal lalpha-->HII phase transition of lipid bilayers: a 31P-NMR and titration calorimetry study. | 1998 | Biochim. Biophys. Acta | pmid:9675291 |
Henshaw JB et al. | Definition of the specific roles of lysolecithin and palmitic acid in altering the susceptibility of dipalmitoylphosphatidylcholine bilayers to phospholipase A2. | 1998 | Biochemistry | pmid:9692961 |
Okajima F et al. | Stimulatory and inhibitory actions of lysophosphatidylcholine, depending on its fatty acid residue, on the phospholipase C/Ca2+ system in HL-60 leukaemia cells. | 1998 | Biochem. J. | pmid:9820828 |
O'Hare MM et al. | Lyso-phosphatidylcholine and outcome of preterm babies with respiratory distress syndrome treated with surfactant. | 1997 | Early Hum. Dev. | pmid:9226120 |
Minami T et al. | Phospholipase A2 stimulates rat gastric epithelial cell line (RGM-1) migration. | 1997 | Inflamm. Res. | pmid:9098723 |
Lee YP et al. | Analysis of human lecithin-cholesterol acyltransferase activity by carboxyl-terminal truncation. | 1997 | Biochim. Biophys. Acta | pmid:9059515 |