1-Palmitoyl-sn-glycero-3-phosphocholine

1-Palmitoyl-sn-glycero-3-phosphocholine is a lipid of Glycerophospholipids (GP) class. 1-palmitoyl-sn-glycero-3-phosphocholine is associated with abnormalities such as Intrahepatic Cholestasis and Dysentery, Shigella dysenteriae. The involved functions are known as Homeostasis, Signal Transduction, Saturated, mRNA Expression and Synthesis. 1-palmitoyl-sn-glycero-3-phosphocholine often locates in Hepatic. The associated genes with 1-Palmitoyl-sn-glycero-3-phosphocholine are PPARA gene, TGFBR2 gene, SMAD3 gene and PLA2G6 gene. The related lipids are Fatty Acids, palmitoyl lysophosphatidylcholine, LYSO-PC and 1-palmitoyl-2-hydroxy-sn-glycero-3-phosphocholine.

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Introduction

To understand associated biological information of 1-Palmitoyl-sn-glycero-3-phosphocholine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with 1-Palmitoyl-sn-glycero-3-phosphocholine?

1-Palmitoyl-sn-glycero-3-phosphocholine is suspected in Intrahepatic Cholestasis, Dysentery, Shigella dysenteriae and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 1-Palmitoyl-sn-glycero-3-phosphocholine

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Arrhythmias, Cardiac D001145 42 associated lipids
Diabetes Mellitus, Type 1 D003922 56 associated lipids
Total 3

PubChem Associated disorders and diseases

What pathways are associated with 1-Palmitoyl-sn-glycero-3-phosphocholine

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with 1-Palmitoyl-sn-glycero-3-phosphocholine?

Related references are published most in these journals:

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What functions are associated with 1-Palmitoyl-sn-glycero-3-phosphocholine?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with 1-Palmitoyl-sn-glycero-3-phosphocholine?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with 1-Palmitoyl-sn-glycero-3-phosphocholine?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with 1-Palmitoyl-sn-glycero-3-phosphocholine?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with 1-Palmitoyl-sn-glycero-3-phosphocholine

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Authors Title Published Journal PubMed Link
Alonso A et al. Lipids favoring inverted phase enhance the ability of aerolysin to permeabilize liposome bilayers. 2000 Biochemistry pmid:11087349
Shi A et al. Lysophosphatidylcholine molecular species in low density lipoprotein and high density lipoprotein in alloxan-induced diabetic rats: effect of probucol. 1999 Exp. Clin. Endocrinol. Diabetes pmid:10543409
Grossmann G et al. Experimental neonatal respiratory failure induced by lysophosphatidylcholine: effect of surfactant treatment. 1999 J. Appl. Physiol. pmid:9931201
Arbibe L et al. Generation of lyso-phospholipids from surfactant in acute lung injury is mediated by type-II phospholipase A2 and inhibited by a direct surfactant protein A-phospholipase A2 protein interaction. 1998 J. Clin. Invest. pmid:9739049
Wenk MR and Seelig J Proton induced vesicle fusion and the isothermal lalpha-->HII phase transition of lipid bilayers: a 31P-NMR and titration calorimetry study. 1998 Biochim. Biophys. Acta pmid:9675291
Henshaw JB et al. Definition of the specific roles of lysolecithin and palmitic acid in altering the susceptibility of dipalmitoylphosphatidylcholine bilayers to phospholipase A2. 1998 Biochemistry pmid:9692961
Okajima F et al. Stimulatory and inhibitory actions of lysophosphatidylcholine, depending on its fatty acid residue, on the phospholipase C/Ca2+ system in HL-60 leukaemia cells. 1998 Biochem. J. pmid:9820828
O'Hare MM et al. Lyso-phosphatidylcholine and outcome of preterm babies with respiratory distress syndrome treated with surfactant. 1997 Early Hum. Dev. pmid:9226120
Minami T et al. Phospholipase A2 stimulates rat gastric epithelial cell line (RGM-1) migration. 1997 Inflamm. Res. pmid:9098723
Lee YP et al. Analysis of human lecithin-cholesterol acyltransferase activity by carboxyl-terminal truncation. 1997 Biochim. Biophys. Acta pmid:9059515