Lysoplasmenylcholine

Lysoplasmenylcholine is a lipid of Glycerophospholipids (GP) class. Lysoplasmenylcholine is associated with abnormalities such as Ischemia, Congenital Abnormality and Myocardial Ischemia. The involved functions are known as membrane activity, Action Potentials, Hypoxia, Energy Absorption and Cell Death. Lysoplasmenylcholine often locates in Myocardium, Membrane, Extracellular, Axon and Sarcolemma. The associated genes with Lysoplasmenylcholine are THOC4 gene, POLE gene, SFLL and CA1 gene. The related lipids are Plasmalogens, Phosphatidylserines, Lysophospholipids, plasmenylcholine and lysoplasmenylcholine.

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Introduction

To understand associated biological information of Lysoplasmenylcholine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Lysoplasmenylcholine?

Lysoplasmenylcholine is suspected in Myocardial Ischemia, Ischemia, Congenital Abnormality and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Lysoplasmenylcholine

MeSH term MeSH ID Detail
Coronary Disease D003327 70 associated lipids
Coronary Artery Disease D003324 47 associated lipids
Total 2

PubChem Associated disorders and diseases

What pathways are associated with Lysoplasmenylcholine

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Lysoplasmenylcholine?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Lysoplasmenylcholine?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Lysoplasmenylcholine?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Lysoplasmenylcholine?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Lysoplasmenylcholine?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Lysoplasmenylcholine

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Authors Title Published Journal PubMed Link
Williams SD and Ford DA Calcium-independent phospholipase A(2) mediates CREB phosphorylation and c-fos expression during ischemia. 2001 Am. J. Physiol. Heart Circ. Physiol. pmid:11406482
Albert CJ et al. Reactive chlorinating species produced by myeloperoxidase target the vinyl ether bond of plasmalogens: identification of 2-chlorohexadecanal. 2001 J. Biol. Chem. pmid:11301330
Jurkowitz MS et al. Identification and characterization of alkenyl hydrolase (lysoplasmalogenase) in microsomes and identification of a plasmalogen-active phospholipase A2 in cytosol of small intestinal epithelium. 1999 Biochim. Biophys. Acta pmid:10064898
Caldwell RA and Baumgarten CM Plasmalogen-derived lysolipid induces a depolarizing cation current in rabbit ventricular myocytes. 1998 Circ. Res. pmid:9734476
McHowat J et al. Selective hydrolysis of plasmalogen phospholipids by Ca2+-independent PLA2 in hypoxic ventricular myocytes. 1998 Am. J. Physiol. pmid:9611139
Creer MH and McHowat J Selective hydrolysis of plasmalogens in endothelial cells following thrombin stimulation. 1998 Am. J. Physiol. pmid:9843711
Williams SD and Ford DA Activation of myocardial cAMP-dependent protein kinase by lysoplasmenylcholine. 1997 FEBS Lett. pmid:9450545
Reiss D et al. Delayed oxidative degradation of polyunsaturated diacyl phospholipids in the presence of plasmalogen phospholipids in vitro. 1997 Biochem. J. pmid:9169616
Schonefeld M et al. Hypoxia-induced amphiphiles inhibit renal Na+, K(+)-ATPase. 1996 Kidney Int. pmid:8731093
Turini ME and Holub BJ Eicosanoid/thromboxane A2-independent and -dependent generation of lysoplasmenylethanolamine via phospholipase A2 in collagen-stimulated human platelets. 1993 Biochem. J. pmid:8435063