| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Colonic Neoplasms | D003110 | 161 associated lipids |
| Alcoholism | D000437 | 27 associated lipids |
| Neoplasms, Glandular and Epithelial | D009375 | 12 associated lipids |
Total
4
4-methylthio-2-oxobutanoic acid
4-methylthio-2-oxobutanoic acid is a lipid of Fatty Acyls (FA) class. The involved functions are known as polyamine biosynthetic process, Anabolism, enzyme activity, enzyme pathway and Process. The associated genes with 4-methylthio-2-oxobutanoic acid are 2-keto-4-methylthiobutyric acid, MTAP gene, Homologous Gene, 2-keto-4-thiomethylbutyrate and Alleles. The related lipids are alpha-ketocaproic acid.
Cross Reference
Introduction
To understand associated biological information of 4-methylthio-2-oxobutanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with 4-methylthio-2-oxobutanoic acid?
There are no associated biomedical information in the current reference collection.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with 4-methylthio-2-oxobutanoic acid
PubChem Associated disorders and diseases
What pathways are associated with 4-methylthio-2-oxobutanoic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with 4-methylthio-2-oxobutanoic acid?
There are no associated biomedical information in the current reference collection.
What functions are associated with 4-methylthio-2-oxobutanoic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with 4-methylthio-2-oxobutanoic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with 4-methylthio-2-oxobutanoic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with 4-methylthio-2-oxobutanoic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with 4-methylthio-2-oxobutanoic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Sumner ET et al. | Transforming activity and therapeutic targeting of C-terminal-binding protein 2 in Apc-mutated neoplasia. | 2017 | Oncogene | pmid:28414304 |
| Korwar S et al. | Design, synthesis, and biological evaluation of substrate-competitive inhibitors of C-terminal Binding Protein (CtBP). | 2016 | Bioorg. Med. Chem. | pmid:27156192 |
| Jia KZ et al. | Clonostachys rosea demethiolase STR3 controls the conversion of methionine into methanethiol. | 2016 | Sci Rep | pmid:26902928 |
| Wang L et al. | CtBP maintains cancer cell growth and metabolic homeostasis via regulating SIRT4. | 2015 | Cell Death Dis | pmid:25633289 |
| Hossain GS et al. | One-step biosynthesis of α-keto-γ-methylthiobutyric acid from L-methionine by an Escherichia coli whole-cell biocatalyst expressing an engineered L-amino acid deaminase from Proteus vulgaris. | 2014 | PLoS ONE | pmid:25531756 |
| Hilbert BJ et al. | Crystal structures of human CtBP in complex with substrate MTOB reveal active site features useful for inhibitor design. | 2014 | FEBS Lett. | pmid:24657618 |
| Nakano T et al. | MtnBD is a multifunctional fusion enzyme in the methionine salvage pathway of Tetrahymena thermophila. | 2013 | PLoS ONE | pmid:23840871 |
| Stankiewicz TR et al. | C-terminal binding proteins are essential pro-survival factors that undergo caspase-dependent downregulation during neuronal apoptosis. | 2013 | Mol. Cell. Neurosci. | pmid:23859824 |
| May T et al. | BRCA1 expression is epigenetically repressed in sporadic ovarian cancer cells by overexpression of C-terminal binding protein 2. | 2013 | Neoplasia | pmid:23730208 |
| Zheng Z et al. | Coordination of auxin and ethylene biosynthesis by the aminotransferase VAS1. | 2013 | Nat. Chem. Biol. | pmid:23377040 |