Iodoacetic acid

Iodoacetic acid is a lipid of Fatty Acyls (FA) class. Iodoacetic acid is associated with abnormalities such as Photoreceptor degeneration and Post MI. The involved functions are known as Hypoxia, Glycolysis, Metabolic Inhibition, Oxidation and PTPS activity. Iodoacetic acid often locates in Extracellular, Muscle, Mitochondria, Cytoplasmic matrix and Tissue membrane. The associated genes with Iodoacetic acid are SLC33A1 gene, GTF2I gene, Mutant Proteins, TRIM33 gene and oxytocin, 1-desamino-(O-Et-Tyr)(2)-.

Cross Reference

Introduction

To understand associated biological information of Iodoacetic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Iodoacetic acid?

Iodoacetic acid is suspected in Photoreceptor degeneration, Post MI and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Iodoacetic acid

MeSH term MeSH ID Detail
Temporomandibular Joint Disorders D013705 4 associated lipids
Arthralgia D018771 8 associated lipids
Osteophyte D054850 2 associated lipids
Glycogen Storage Disease D006008 4 associated lipids
Hypertrophy, Left Ventricular D017379 12 associated lipids
Retinitis D012173 4 associated lipids
Theileriasis D013801 7 associated lipids
Muscle Cramp D009120 3 associated lipids
Rigor Mortis D012298 1 associated lipids
Thrombophilia D019851 6 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Iodoacetic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Iodoacetic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Iodoacetic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Iodoacetic acid?

There are no associated biomedical information in the current reference collection.

What genes are associated with Iodoacetic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Iodoacetic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Iodoacetic acid

Download all related citations
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Authors Title Published Journal PubMed Link
Wei Y et al. Transient Receptor Potential Vanilloid 5 Mediates Ca2+ Influx and Inhibits Chondrocyte Autophagy in a Rat Osteoarthritis Model. 2017 Cell. Physiol. Biochem. pmid:28535500
McDougall JJ et al. Lysophosphatidic acid provides a missing link between osteoarthritis and joint neuropathic pain. 2017 Osteoarthr. Cartil. pmid:27651153
Thirunavukkarasu K et al. Identification and pharmacological characterization of a novel inhibitor of autotaxin in rodent models of joint pain. 2017 Osteoarthr. Cartil. pmid:27638130
Burston JJ et al. Robust anti-nociceptive effects of monoacylglycerol lipase inhibition in a model of osteoarthritis pain. 2016 Br. J. Pharmacol. pmid:27501482
Otis C et al. Concurrent validity of different functional and neuroproteomic pain assessment methods in the rat osteoarthritis monosodium iodoacetate (MIA) model. 2016 Arthritis Res. Ther. pmid:27338815
Pitcher T et al. The Monoiodoacetate Model of Osteoarthritis Pain in the Mouse. 2016 J Vis Exp pmid:27214709
Ziaei A et al. Preliminary investigation of the effects of topical mixture of Lawsonia inermis L. and Ricinus communis L. leaves extract in treatment of osteoarthritis using MIA model in rats. 2016 Daru pmid:27142000
Abaei M et al. Neural correlates of hyperalgesia in the monosodium iodoacetate model of osteoarthritis pain. 2016 Mol Pain pmid:27068285
Miyamoto S et al. Intra-articular injection of mono-iodoacetate induces osteoarthritis of the hip in rats. 2016 BMC Musculoskelet Disord pmid:26992380
Nwosu LN et al. Blocking the tropomyosin receptor kinase A (TrkA) receptor inhibits pain behaviour in two rat models of osteoarthritis. 2016 Ann. Rheum. Dis. pmid:26286016