Itaconic acid

Itaconic acid is a lipid of Fatty Acyls (FA) class. Itaconic acid is associated with abnormalities such as Tuberculosis and Bacterial Infections. The involved functions are known as Metabolic Inhibition, Gene Expression, Anabolism, Citric Acid Cycle and physiological aspects. Itaconic acid often locates in Protoplasm and Chromosomes, Human, Pair 13. The associated genes with Itaconic acid are Homologous Gene, IRG1 gene and Genome, Human. The related lipids are Propionate and Lipopolysaccharides.

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Introduction

To understand associated biological information of Itaconic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Itaconic acid?

Itaconic acid is suspected in Tuberculosis, Bacterial Infections and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Itaconic acid

PubChem Associated disorders and diseases

What pathways are associated with Itaconic acid

Lipid pathways are not clear in current pathway databases. We organized associated pathways with Itaconic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
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PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Itaconic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Itaconic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Itaconic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Itaconic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Itaconic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Itaconic acid

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Authors Title Published Journal PubMed Link
Farmer TJ et al. Synthesis of Unsaturated Polyester Resins from Various Bio-Derived Platform Molecules. 2015 Int J Mol Sci pmid:26147423
Kronen M et al. Mesaconase Activity of Class I Fumarase Contributes to Mesaconate Utilization by Burkholderia xenovorans. 2015 Appl. Environ. Microbiol. pmid:26070669
Kyzas GZ et al. Poly(itaconic acid)-grafted chitosan adsorbents with different cross-linking for Pb(II) and Cd(II) uptake. 2014 Langmuir pmid:24011255
Moynihan MM and Murkin AS Cysteine is the general base that serves in catalysis by isocitrate lyase and in mechanism-based inhibition by 3-nitropropionate. 2014 Biochemistry pmid:24354272
Zhang M et al. The preparation of magnetic molecularly imprinted nanoparticles for the recognition of bovine hemoglobin. 2014 Talanta pmid:24468385
Sasikaran J et al. Bacterial itaconate degradation promotes pathogenicity. 2014 Nat. Chem. Biol. pmid:24657929
van der Straat L et al. Expression of the Aspergillus terreus itaconic acid biosynthesis cluster in Aspergillus niger. 2014 Microb. Cell Fact. pmid:24438100
Huang X et al. Cloning, characterization and application of a glyceraldehyde-3-phosphate dehydrogenase promoter from Aspergillus terreus. 2014 J. Ind. Microbiol. Biotechnol. pmid:24306453
Okamoto S et al. Production of itaconic acid using metabolically engineered Escherichia coli. 2014 J. Gen. Appl. Microbiol. pmid:25420424
Huang X et al. Improving itaconic acid production through genetic engineering of an industrial Aspergillus terreus strain. 2014 Microb. Cell Fact. pmid:25162789