erythromycin

erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.

Cross Reference

Introduction

To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with erythromycin?

erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with erythromycin

MeSH term MeSH ID Detail
Hematemesis D006396 1 associated lipids
Carbuncle D002270 1 associated lipids
Gastric Outlet Obstruction D017219 1 associated lipids
Gas Gangrene D005738 1 associated lipids
Sebaceous Gland Diseases D012625 1 associated lipids
Atrioventricular Block D054537 1 associated lipids
Erysipelas D004886 1 associated lipids
Endocarditis, Subacute Bacterial D004698 1 associated lipids
Lacrimal Duct Obstruction D007767 1 associated lipids
Choanal Atresia D002754 1 associated lipids
Scarlet Fever D012541 1 associated lipids
Dacryocystitis D003607 1 associated lipids
Erythrasma D004894 1 associated lipids
Granuloma, Respiratory Tract D015769 1 associated lipids
Pilonidal Sinus D010864 1 associated lipids
Postoperative Nausea and Vomiting D020250 1 associated lipids
Vagus Nerve Injuries D061223 1 associated lipids
Focal Infection, Dental D005491 1 associated lipids
Maxillofacial Injuries D008446 1 associated lipids
Sialadenitis D012793 1 associated lipids
Jaw Abnormalities D007569 1 associated lipids
Lymphoma, B-Cell, Marginal Zone D018442 1 associated lipids
Pericarditis, Constrictive D010494 1 associated lipids
Microphthalmos D008850 1 associated lipids
Peritonsillar Abscess D000039 1 associated lipids
Staphylococcal Scalded Skin Syndrome D013206 1 associated lipids
Actinomycosis, Cervicofacial D000197 1 associated lipids
Ophthalmia Neonatorum D009878 1 associated lipids
Peliosis Hepatis D010382 1 associated lipids
Epidural Abscess D020802 1 associated lipids
Skin Diseases, Vascular D017445 1 associated lipids
Angiomatosis D000798 1 associated lipids
Syphilis, Cardiovascular D013589 1 associated lipids
Chalazion D017043 1 associated lipids
Parapsoriasis D010267 1 associated lipids
Stomatognathic Diseases D009057 1 associated lipids
Typhus, Epidemic Louse-Borne D014438 1 associated lipids
Myiasis D009198 1 associated lipids
Keratoderma, Palmoplantar D007645 1 associated lipids
Splenic Infarction D013159 1 associated lipids
Thyroid Crisis D013958 1 associated lipids
Trench Fever D014205 1 associated lipids
Papillon-Lefevre Disease D010214 1 associated lipids
Meningitis, Listeria D008584 1 associated lipids
Digestive System Abnormalities D004065 1 associated lipids
Occupational Injuries D060051 1 associated lipids
Hereditary Sensory and Autonomic Neuropathies D009477 1 associated lipids
Megacolon D008531 1 associated lipids
Syphilis, Cutaneous D013591 1 associated lipids
Pneumonia, Ventilator-Associated D053717 1 associated lipids
Spider Bites D001098 1 associated lipids
Choroiditis D002833 1 associated lipids
Epidermitis, Exudative, of Swine D004818 1 associated lipids
Heart Murmurs D006337 1 associated lipids
Prolapse D011391 1 associated lipids
Compartment Syndromes D003161 1 associated lipids
Fecal Incontinence D005242 1 associated lipids
Rat-Bite Fever D011906 1 associated lipids
Pelvic Infection D034161 1 associated lipids
Nasopharyngeal Diseases D009302 2 associated lipids
Rickettsiaceae Infections D012288 2 associated lipids
Pneumonia, Staphylococcal D011023 2 associated lipids
Gardner Syndrome D005736 2 associated lipids
Bile Reflux D001655 2 associated lipids
Wounds, Gunshot D014948 2 associated lipids
Granuloma, Lethal Midline D006103 2 associated lipids
Rubella D012409 2 associated lipids
Seroma D049291 2 associated lipids
Furunculosis D005667 2 associated lipids
Porphyrias D011164 2 associated lipids
Periodontal Abscess D010508 2 associated lipids
Hyperemesis Gravidarum D006939 2 associated lipids
Pancreatic Fistula D010185 2 associated lipids
Bites, Human D001734 2 associated lipids
Hearing Loss, Conductive D006314 2 associated lipids
Pericoronitis D010497 2 associated lipids
Herpes Zoster Ophthalmicus D006563 2 associated lipids
Abdominal Abscess D018784 2 associated lipids
Protein-Losing Enteropathies D011504 2 associated lipids
Hypoventilation D007040 2 associated lipids
Uterine Cervical Erosion D002579 2 associated lipids
Duodenogastric Reflux D004383 2 associated lipids
Neuroaspergillosis D020953 2 associated lipids
Common Cold D003139 2 associated lipids
Chlamydiaceae Infections D002694 2 associated lipids
Hyperhidrosis D006945 2 associated lipids
Lupus Erythematosus, Cutaneous D008178 2 associated lipids
Empyema, Pleural D016724 2 associated lipids
Tooth Diseases D014076 2 associated lipids
Animal Diseases D000820 2 associated lipids
Angiomatosis, Bacillary D016917 2 associated lipids
Torsades de Pointes D016171 2 associated lipids
Granulomatosis, Orofacial D051261 2 associated lipids
Hemoglobin SC Disease D006450 2 associated lipids
Dental Enamel Hypoplasia D003744 2 associated lipids
Auditory Diseases, Central D001304 2 associated lipids
Skin Diseases, Papulosquamous D017444 2 associated lipids
Granuloma, Pyogenic D017789 2 associated lipids
Diphtheria D004165 2 associated lipids
Granuloma Inguinale D006100 2 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with erythromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with erythromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with erythromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with erythromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with erythromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with erythromycin?

Mouse Model

Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).

Knock-out

Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with erythromycin

Download all related citations
Per page 10 20 50 100 | Total 13660
Authors Title Published Journal PubMed Link
Khair OA et al. Effect of erythromycin on Haemophilus influenzae endotoxin-induced release of IL-6, IL-8 and sICAM-1 by cultured human bronchial epithelial cells. 1995 Eur. Respir. J. pmid:8575568
Kerr JR and Moore JE Potential for erythromycin resistance in porcine Campylobacter species. 1995 Trends Microbiol. pmid:8574518
Lynch HC and Bushell ME The physiology of erythromycin biosynthesis in cyclic fed batch culture. 1995 Microbiology (Reading, Engl.) pmid:8574403
Goswami BB et al. Physico-chemical properties and biological activities of erythromycin nalidixate. 1995 Arzneimittelforschung pmid:8573228
Roberts MC et al. Transferable erythromycin resistance in Listeria spp. isolated from food. 1996 Appl. Environ. Microbiol. pmid:8572704
Ishiura Y et al. Additive effect of continuous low-dose ofloxacin on erythromycin therapy for sinobronchial syndrome. 1995 Respir Med pmid:8570882
Tait A and Knowles JK Characterization of mitochondrial and cytoplasmic ribosomes from Paramecium aurelia. 1977 J. Cell Biol. pmid:856828
Christie CD et al. Containment of pertussis in the regional pediatric hospital during the Greater Cincinnati epidemic of 1993. 1995 Infect Control Hosp Epidemiol pmid:8568199
Cherry JD Nosocomial pertussis in the nineties. 1995 Infect Control Hosp Epidemiol pmid:8568198
Leyh F [Syphilis therapy--results of an inquiry]. 1977 Hautarzt pmid:856770
Martins C et al. Allergic contact dermatitis from erythromycin. 1995 Contact Derm. pmid:8565504
Kelly DJ et al. Rickettsia tsutsugamushi infection in cell culture: antibiotic susceptibility determined by flow cytometry. 1995 Am. J. Trop. Med. Hyg. pmid:8561261
Arroyo J and Medoff G Mycobacterium chelonei infection: successful treatment based on a radiometric susceptibility test. 1977 Antimicrob. Agents Chemother. pmid:856032
Allen NE Macrolide resistance in Staphylococcus aureus: inducers of macrolide resistance. 1977 Antimicrob. Agents Chemother. pmid:856018
Moriyama H et al. Evaluation of endoscopic sinus surgery for chronic sinusitis: post-operative erythromycin therapy. 1995 Rhinology pmid:8560171
Mitsuyama T et al. Inhibition by erythromycin of superoxide anion production by human polymorphonuclear leukocytes through the action of cyclic AMP-dependent protein kinase. 1995 Respiration pmid:8560094
Tauch A et al. The Corynebacterium xerosis composite transposon Tn5432 consists of two identical insertion sequences, designated IS1249, flanking the erythromycin resistance gene ermCX. 1995 Plasmid pmid:8559800
Tateishi T et al. Omeprazole does not affect measured CYP3A4 activity using the erythromycin breath test. 1995 Br J Clin Pharmacol pmid:8554946
Fujii T et al. Long term effect of erythromycin therapy in patients with chronic Pseudomonas aeruginosa infection. 1995 Thorax pmid:8553295
Kawahara S et al. Inhibitory effect of ofloxacin on acute exacerbations of chronic respiratory tract infections in comparison with erythromycin. 1995 Drugs pmid:8549382
Fujimura M et al. Additive effect of continuous low dose ofloxacin on erythromycin therapy for sinobronchial syndrome. 1995 Drugs pmid:8549380
Saito A and Gaja M In vitro and in vivo activities of sparfloxacin in Legionella infections. 1995 Drugs pmid:8549320
Morrissey I and Smith JT Activity of new 4-quinolones in combination with erythromycin or tetracycline against S. pneumoniae. 1995 Drugs pmid:8549311
Bojar RA et al. Direct analysis of resistance in the cutaneous microflora during treatment of acne vulgaris with topical 1% nadifloxacin and 2% erythromycin. 1995 Drugs pmid:8549289
Stein CM et al. Comparison of the dapsone recovery ratio and the erythromycin breath test as in vivo probes of CYP3A activity in patients with rheumatoid arthritis receiving cyclosporine. 1996 Clin. Pharmacol. Ther. pmid:8549033
Brown GR Erythromycin-induced hypotension. 1995 Ann Pharmacother pmid:8547744
Ducloux D et al. [Pseudo-cholangitis, a form of erythromycin-induced hepatitis]. 1995 Presse Med pmid:8545387
Kenney DG et al. Development of reactive arthritis and resistance to erythromycin and rifampin in a foal during treatment for Rhodococcus equi pneumonia. 1994 Equine Vet. J. pmid:8542848
Tissi L et al. In vivo efficacy of azithromycin in treatment of systemic infection and septic arthritis induced by type IV group B Streptococcus strains in mice: comparative study with erythromycin and penicillin G. 1995 Antimicrob. Agents Chemother. pmid:8540695
Veber B and Pocidalo JJ [The particular case of azalides: antibiotic diapedesis. Experimental data from a murine model of pneumococcal pneumonia]. 1995 Pathol. Biol. pmid:8539075
Lagrange PH [Azithromycin, pharmacodynamic evaluation in animal models]. 1995 Pathol. Biol. pmid:8539074
Philippon A et al. [Azithromycin: critical points]. 1995 Pathol. Biol. pmid:8539070
Pechère JC [Effect of the molecular structure of azithromycin on pharmacokinetics and the antimicrobial activity]. 1995 Pathol. Biol. pmid:8539069
Littenberg B et al. A randomized controlled trial of oral albuterol in acute cough. 1996 J Fam Pract pmid:8537805
Hosie J et al. A comparison of 5 days of dirithromycin and 7 days of clarithromycin in acute bacterial exacerbation of chronic bronchitis. 1995 J. Antimicrob. Chemother. pmid:8537264
Doucet-Populaire F et al. Acquired resistance in Mycobacterium avium complex strains isolated from AIDS patients and beige mice during treatment with clarithromycin. 1995 J. Antimicrob. Chemother. pmid:8537260
Shiba Y et al. Effect of nonpeptide motilin agonist EM523 on release of gut and pancreatic hormones in conscious dogs. 1996 Gastroenterology pmid:8536863
Hoppe JE and Tschirner T Comparison of media for agar dilution susceptibility testing of Bordetella pertussis and Bordetella parapertussis. 1995 Eur. J. Clin. Microbiol. Infect. Dis. pmid:8536725
Izumikawa K et al. [The therapeutic effect of doxycycline (Vibramycin) on pneumonia due to mycoplasma pneumoniae (author's transl)]. 1977 Jpn J Antibiot pmid:853569
Benzamycin gel for acne. 1995 Drug Ther Bull pmid:8529541
Lestico MR and Smith AD Stevens-Johnson syndrome following erythromycin administration. 1995 Am J Health Syst Pharm pmid:8528839
Tee W et al. Emergence of multidrug resistance in Campylobacter jejuni isolates from three patients infected with human immunodeficiency virus. 1995 Clin. Infect. Dis. pmid:8527556
Kelentey BA and Kelentey BJ [Excretion of erythromycin, clindamycin and lincomycin into the saliva]. 1995 Fogorv Sz pmid:8522016
González Carro P et al. [Acute pancreatitis and erythromycin]. 1995 Rev Esp Enferm Dig pmid:8519548
Baird RM Antimicrobial drug use in hospitals. 1977 Can Med Assoc J pmid:851926
Suriñach JM et al. [Acute pancreatitis from erythromycin]. 1993 Rev Clin Esp pmid:8516513
Nakata M et al. Synthetic studies of erythromycin derivatives. Synthesis and antimicrobial activities of 3''-EPI-erythromycin A and (9S)-11-dehydroxy-9-deoxo-9-hydroxy-11- oxoerythromycin A. 1993 J. Antibiot. pmid:8514636
Kepczyk T et al. Effect of intravenous erythromycin on gastric emptying. 1993 May-Jun Gastrointest. Endosc. pmid:8514093
Narchi P et al. Interactions of pre-operative erythromycin administration with general anaesthesia. 1993 Can J Anaesth pmid:8513524
Suata K et al. Antimicrobial susceptibility patterns and resistance transferability among Bacteroides fragilis group isolates from patients with appendicitis in Bali, Indonesia. 1993 Clin. Infect. Dis. pmid:8513066
Siminoski K Persistent fever due to occult dental infection: case report and review. 1993 Clin. Infect. Dis. pmid:8513063
Varga DW Learning in the real world. 1993 J Ky Med Assoc pmid:8509688
Roberts GA et al. Heterologous expression in Escherichia coli of an intact multienzyme component of the erythromycin-producing polyketide synthase. 1993 Eur. J. Biochem. pmid:8508800
Kawamura O et al. Effect of erythromycin derivative EM523L on human interdigestive gastrointestinal tract. 1993 Dig. Dis. Sci. pmid:8508696
Lemaire F et al. [Erythromycin therapy of incidences of superinfection in chronic respiratory insufficiency]. 1977 Nouv Presse Med pmid:850633
Altemeir WA and Ayoub EM Erythromycin prophylaxis for pertussis. 1977 Pediatrics pmid:850603
Danielson ND et al. Simple methods for the qualitative identification and quantitative determination of macrolide antibiotics. 1993 J Pharm Biomed Anal pmid:8504183
Sacristán JA et al. Ototoxicity of erythromycin in man: electrophysiologic approach. 1993 Am J Otol pmid:8503495
Oğünç G et al. [Legionnaires' disease following kidney transplantation]. 1993 Mikrobiyol Bul pmid:8502185
Faghin R et al. Acid degradation studies of 6-deoxyerythromycin A. 1993 J. Antibiot. pmid:8501017
Watanabe Y et al. Chemical modification of erythromycins. IX. Selective methylation at the C-6 hydroxyl group of erythromycin A oxime derivatives and preparation of clarithromycin. 1993 J. Antibiot. pmid:8501007
Levison ME et al. In vitro activity and clinical efficacy of clindamycin in the treatment of infections due to anaerobic bacteria. 1977 J. Infect. Dis. pmid:850091
Iino Y et al. Erythromycin therapy for otitis media with effusion in sinobronchial syndrome. 1993 Arch. Otolaryngol. Head Neck Surg. pmid:8499096
Prather CM et al. Gastric axial forces in experimentally delayed and accelerated gastric emptying. 1993 Am. J. Physiol. pmid:8498519
Tredaniel J et al. Diffuse panbronchiolitis: efficacy of low-dose erythromycin. 1993 Respir Med pmid:8497706
Edelstein PH and Edelstein MA In vitro activity of RP 74501-RP 74502, a novel streptogramin antimicrobial mixture, against clinical isolates of Legionella species. 1993 Antimicrob. Agents Chemother. pmid:8494390
Foweraker JE et al. Ecology of Haemophilus influenzae and Haemophilus parainfluenzae in sputum and saliva and effects of antibiotics on their distribution in patients with lower respiratory tract infections. 1993 Antimicrob. Agents Chemother. pmid:8494378
Tankovic J et al. Antimicrobial susceptibility of Pediococcus spp. and genetic basis of macrolide resistance in Pediococcus acidilactici HM3020. 1993 Antimicrob. Agents Chemother. pmid:8494376
Tateda K et al. Effects of sub-MICs of erythromycin and other macrolide antibiotics on serum sensitivity of Pseudomonas aeruginosa. 1993 Antimicrob. Agents Chemother. pmid:8494362
Piras G et al. Cloning and sequencing of the low-affinity penicillin-binding protein 3r-encoding gene of Enterococcus hirae S185: modular design and structural organization of the protein. 1993 J. Bacteriol. pmid:8491705
Grøndahl TO and Langmoen IA Epileptogenic effect of antibiotic drugs. 1993 J. Neurosurg. pmid:8487076
Soriano F and Fernández-Roblas R High rates of erythromycin-resistant Streptococcus pneumoniae among penicillin-resistant strains. 1993 J. Antimicrob. Chemother. pmid:8486579
Savolainen S et al. Peritonsillar abscess. Clinical and microbiologic aspects and treatment regimens. 1993 Arch. Otolaryngol. Head Neck Surg. pmid:8484941
Doménech J et al. [Evaluation of the possible ototoxicity of josamycin by high frequency audiometry]. 1993 An Otorrinolaringol Ibero Am pmid:8484488
Rathore MH and Jenkins SG Group A beta-hemolytic Streptococcus: issue of resistance. 1993 Pediatr. Infect. Dis. J. pmid:8483636
Gustafsson BE et al. Prolonged induction of germfree bile acid pattern in conventional rats by antibiotics. 1977 Acta Med Scand pmid:848350
Orr PH et al. Randomized placebo-controlled trials of antibiotics for acute bronchitis: a critical review of the literature. 1993 J Fam Pract pmid:8482934
Ohtawa M et al. Mechanism of gastroprokinetic effect of EM523, an erythromycin derivative, in dogs. 1993 Gastroenterology pmid:8482446
Kawamura O et al. Effect of erythromycin on interdigestive gastrointestinal contractile activity and plasma motilin concentration in humans. 1993 Dig. Dis. Sci. pmid:8482186
Derby LE et al. Erythromycin-associated cholestatic hepatitis. 1993 Med. J. Aust. pmid:8479375
Müller O and Wettich K Clinical efficacy of dirithromycin in pharyngitis and tonsillitis. 1993 J. Antimicrob. Chemother. pmid:8478316
Derriennic M et al. Dirithromycin in the treatment of streptococcal pharyngitis. 1993 J. Antimicrob. Chemother. pmid:8478315
Bergogne-Bérézin E Tissue distribution of dirithromycin: comparison with erythromycin. 1993 J. Antimicrob. Chemother. pmid:8478314
Sides GD et al. Pharmacokinetics of dirithromycin. 1993 J. Antimicrob. Chemother. pmid:8478313
Labro MT et al. Modulation of human polymorphonuclear neutrophil function by macrolides: preliminary data concerning dirithromycin. 1993 J. Antimicrob. Chemother. pmid:8478312
Bauernfeind A In-vitro activity of dirithromycin in comparison with other new and established macrolides. 1993 J. Antimicrob. Chemother. pmid:8478311
Barry AL et al. Dirithromycin disc susceptibility tests: interpretative criteria and quality control parameters. 1993 J. Antimicrob. Chemother. pmid:8478310
Sides GD and Conforti PM Safety profile of dirithromycin. 1993 J. Antimicrob. Chemother. pmid:8478309
Varanese L Pharmacokinetics and safety of dirithromycin in the elderly. 1993 J. Antimicrob. Chemother. pmid:8478308
Derriennic M and Escande JP Dirithromycin in the treatment of skin and skin structure infections. 1993 J. Antimicrob. Chemother. pmid:8478307
Pozzi E Clinical efficacy of dirithromycin versus miocamycin in the treatment of acute bronchitis or acute exacerbations of chronic bronchitis. 1993 J. Antimicrob. Chemother. pmid:8478306
Gaillat J A multicentre study comparing the safety and efficacy of dirithromycin with erythromycin in the treatment of bronchitis. 1993 J. Antimicrob. Chemother. pmid:8478305
Sides GD Clinical efficacy of dirithromycin in acute exacerbations of chronic bronchitis. 1993 J. Antimicrob. Chemother. pmid:8478304
Jacobson K Clinical efficacy of dirithromycin in pneumonia. 1993 J. Antimicrob. Chemother. pmid:8478303
Ruggiero G et al. Clinical efficacy of dirithromycin versus miocamycin in tonsillopharyngitis. 1993 J. Antimicrob. Chemother. pmid:8478300
Endou K et al. Implication of cohesive binding of a macrolide antibiotic, rokitamycin, to ribosomes from Staphylococcus aureus. 1993 J. Antibiot. pmid:8478265
Husfeldt P et al. Antibiotic treatment of sinusitis in general practice. A double-blind study comparing ofloxacin and erythromycin. 1993 Eur Arch Otorhinolaryngol pmid:8476582
Gannon H Ureaplasma urealyticum and its role in neonatal lung disease. 1993 Neonatal Netw pmid:8474408
Garlaschi ML et al. Antimicrobial resistance among clinical isolates of Haemophilus influenzae in northern Italy. Collaborative Study on Pediatric Infectious Diseases. 1993 Eur. J. Epidemiol. pmid:8472803
Smith GR and Thornton EA Effect of disturbance of the gastrointestinal microflora on the faecal excretion of Fusobacterium necrophorum biovar A. 1993 Epidemiol. Infect. pmid:8472777